Citations for
1FOXP1, GPR132, IKZF1
Direct interaction of Ikaros and Foxp1 modulates expression of the G protein-coupled receptor G2A in B-lymphocytes and acute lymphoblastic leukemia.
Bond J, Domaschenz R, Roman-Trufero M, Sabbattini P, Ferreiros-Vidal I, Gerrard G, Asnafi V, Macintyre E, Merkenschlager M, Dillon N.
Oncotarget ncotarget. 2016 Aug 30. doi: 10.18632/oncotarget.11688. [Epub ahead of print] 2016
2ESR1, FOXP1
The expression and correlation between the transcription factor FOXP1 and estrogen receptors in epithelial ovarian cancer.
Hu Z, Zhu L, Tan M, Cai M, Deng L, Yu G, Liu D, Liu J, Lin B.
Biochimie 109:42-8. doi: 10.1016/j.biochi.2014.12.001. Epub 2014 Dec 10. 2015
3FOXP1
FOXP1 inhibits cell growth and attenuates tumorigenicity of neuroblastoma.
Ackermann S, Kocak H, Hero B, Ehemann V, Kahlert Y, Oberthuer A, Roels F, Theißen J, Odenthal M, Berthold F, Fischer M.
BMC Cancer 14:840. doi: 10.1186/1471-2407-14-840. 2014
4FOXP1
FOXP1 directly represses transcription of proapoptotic genes and cooperates with NF-κB to promote survival of human B cells.
van Keimpema M, Grüneberg LJ, Mokry M, van Boxtel R, Koster J, Coffer PJ, Pals ST, Spaargaren M.
Blood 124(23):3431-40. doi: 10.1182/blood-2014-01-553412. Epub 2014 Sep 29. 2014
5FOXP1
Brain-specific Foxp1 deletion impairs neuronal development and causes autistic-like behaviour.
Bacon C, Schneider M, Le Magueresse C, Froehlich H, Sticht C, Gluch C, Monyer H, Rappold GA.
Mol Psychiatry ol Psychiatry. 2014 Sep 30. doi: 10.1038/mp.2014.116. [Epub ahead of print] 2014
6DLCRM, EIF4A3, FOXP1
Delineation of the 3p14.1p13 microdeletion associated with syndromic distal limb contractures.
Thevenon J, Monnier N, Callier P, Dieterich K, Francoise M, Montgomery T, Kjaergaard S, Neas K, Dixon J, Dahm TL, Huet F, Ragon C, Mosca-Boidron AL, Marle N, Duplomb L, Aubriot-Lorton MH, Mugneret F, Vokes SA, Tucker HW, Lunardi J, Faivre L, Jouk PS, Thauvin-Robinet C.
Am J Med Genet A 164A(12):3027-34. doi: 10.1002/ajmg.a.36751. Epub 2014 Sep 24. 2014
7FOXP1
The transcription factor Foxp1 is a critical negative regulator of the differentiation of follicular helper T cells.
Wang H, Geng J, Wen X, Bi E, Kossenkov AV, Wolf AI, Tas J, Choi YS, Takata H, Day TJ, Chang LY, Sprout SL, Becker EK, Willen J, Tian L, Wang X, Xiao C, Jiang P, Crotty S, Victora GD, Showe LC, Tucker HO, Erikson J, Hu H.
Nat Immunol 15(7):667-75. doi: 10.1038/ni.2890. Epub 2014 May 25. 2014
8FOXP1, MRLA
FOXP1 mutations cause intellectual disability and a recognizable phenotype.
Le Fevre AK, Taylor S, Malek NH, Horn D, Carr CW, Abdul-Rahman OA, O'Donnell S, Burgess T, Shaw M, Gecz J, Bain N, Fagan K, Hunter MF.
Am J Med Genet A 161A(12):3166-75. doi: 10.1002/ajmg.a.36174. Epub 2013 Sep 24. 2013
9FOXP1, SEMA5B
FoxP1 stimulates angiogenesis by repressing the inhibitory guidance protein semaphorin 5B in endothelial cells.
Grundmann S, Lindmayer C, Hans FP, Hoefer I, Helbing T, Pasterkamp G, Bode C, de Kleijn D, Moser M.
PLoS One 8(9):e70873. doi: 10.1371/journal.pone.0070873. eCollection 2013. 2013
10FGF18, FOXP1
Foxp1 maintains hair follicle stem cell quiescence through regulation of Fgf18.
Leishman E, Howard JM, Garcia GE, Miao Q, Ku AT, Dekker JD, Tucker H, Nguyen H.
Development 140(18):3809-18. doi: 10.1242/dev.097477. Epub 2013 Aug 14. 2013
11FOXP1
FOXP1 acts through a negative feedback loop to suppress FOXO-induced apoptosis.
van Boxtel R, Gomez-Puerto C, Mokry M, Eijkelenboom A, van der Vos KE, Nieuwenhuis EE, Burgering BM, Lam EW, Coffer PJ.
Cell Death Differ 20(9):1219-29. doi: 10.1038/cdd.2013.81. Epub 2013 Jul 5. 2013
12FOXP1
Downregulation of FOXP1 is required during germinal center B-cell function.
Sagardoy A, Martinez-Ferrandis JI, Roa S, Bunting KL, Aznar MA, Elemento O, Shaknovich R, Fontán L, Fresquet V, Perez-Roger I, Robles EF, De Smedt L, Sagaert X, Melnick A, Martinez-Climent JA.
Blood 121(21):4311-20. doi: 10.1182/blood-2012-10-462846. Epub 2013 Apr 11. 2013
13FOXP1
Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.
Tang B, Becanovic K, Desplats PA, Spencer B, Hill AM, Connolly C, Masliah E, Leavitt BR, Thomas EA.
Hum Mol Genet 21(14):3097-111. doi: 10.1093/hmg/dds132. Epub 2012 Apr 6. 2012
14FOXP1, FOXP2
The distinct and overlapping phenotypic spectra of FOXP1 and FOXP2 in cognitive disorders.
Bacon C, Rappold GA.
Hum Genet 131(11):1687-98. doi: 10.1007/s00439-012-1193-z. Epub 2012 Jun 27. Review. 2012
15FOXP1, GRIN2B, LAMC3, SCN1A
Exome sequencing in sporadic autism spectrum disorders identifies severe de novo mutations.
O'Roak BJ, Deriziotis P, Lee C, Vives L, Schwartz JJ, Girirajan S, Karakoc E, Mackenzie AP, Ng SB, Baker C, Rieder MJ, Nickerson DA, Bernier R, Fisher SE, Shendure J, Eichler EE.
Nat Genet 43(6):585-9. Epub 2011 May 15. 2011
16FOXP1, MKI67
Expression of the Forkhead transcription factor FOXP1 is associated with tumor grade and Ki67 expression in clear cell renal cell carcinoma.
Toma MI, Weber T, Meinhardt M, Zastrow S, Grimm MO, Füssel S, Wirth MP, Baretton GB.
Cancer Invest 29(2):123-9. Epub 2011 Jan 6. 2011
17FOXP1
An alternative splicing switch regulates embryonic stem cell pluripotency and reprogramming.
Gabut M, Samavarchi-Tehrani P, Wang X, Slobodeniuc V, O'Hanlon D, Sung HK, Alvarez M, Talukder S, Pan Q, Mazzoni EO, Nedelec S, Wichterle H, Woltjen K, Hughes TR, Zandstra PW, Nagy A, Wrana JL, Blencowe BJ.
Cell 147(1):132-46. Epub 2011 Sep 15. 2011
18FOXP1, PAX5
FOXP1 and PAX5 are rare but recurrent translocations partners in acute lymphoblastic leukemia.
Put N, Deeren D, Michaux L, Vandenberghe P.
Cancer Genet 204(8):462-4. 2011
19FOXP1, NFATC4
Opposing roles of FoxP1 and Nfat3 in transcriptional control of cardiomyocyte hypertrophy.
Bai S, Kerppola TK.
Mol Cell Biol 31(14):3068-80. Epub 2011 May 23. 2011
20ABL1, FOXP1, SNX2
Identification of FOXP1 and SNX2 as novel ABL1 fusion partners in acute lymphoblastic leukaemia.
Ernst T, Score J, Deininger M, Hidalgo-Curtis C, Lackie P, Ershler WB, Goldman JM, Cross NC, Grand F.
Br J Haematol 153(1):43-6. doi: 10.1111/j.1365-2141.2010.08457.x. Epub 2011 Feb 1. 2011
21CCR6, FOXP1
Common variants in FOXP1 are associated with generalized vitiligo.
Jin Y, Birlea SA, Fain PR, Mailloux CM, Riccardi SL, Gowan K, Holland PJ, Bennett DC, Wallace MR, McCormack WT, Kemp EH, Gawkrodger DJ, Weetman AP, Picardo M, Leone G, Taďeb A, Jouary T, Ezzedine K, van Geel N, Lambert J, Overbeck A, Spritz RA.
Nat Genet 42(7):576-8. Epub 2010 Jun 6.PMID: 20526340 2010
22FOXP1, MRLA
De novo mutations in FOXP1 in cases with intellectual disability, autism, and language impairment.
Hamdan FF, Daoud H, Rochefort D, Piton A, Gauthier J, Langlois M, Foomani G, Dobrzeniecka S, Krebs MO, Joober R, Lafreničre RG, Lacaille JC, Mottron L, Drapeau P, Beauchamp MH, Phillips MS, Fombonne E, Rouleau GA, Michaud JL.
Am J Hum Genet 87(5):671-8. Epub 2010 Oct 14.PMID: 20950788 2010
23FOXP1, MRLA
Chiari I malformation, delayed gross motor skills, severe speech delay, and epileptiform discharges in a child with FOXP1 haploinsufficiency.
Carr CW, Moreno-De-Luca D, Parker C, Zimmerman HH, Ledbetter N, Martin CL, Dobyns WB, Abdul-Rahman OA.
Eur J Hum Genet 18(11):1216-20. Epub 2010 Jun 23. 2010
24FOXP1, MRLA
Identification of FOXP1 deletions in three unrelated patients with mental retardation and significant speech and language deficits.
Horn D, Kapeller J, Rivera-Brugués N, Moog U, Lorenz-Depiereux B, Eck S, Hempel M, Wagenstaller J, Gawthrope A, Monaco AP, Bonin M, Riess O, Wohlleber E, Illig T, Bezzina CR, Franke A, Spranger S, Villavicencio-Lorini P, Seifert W, Rosenfeld J, Klopocki E, Rappold GA, Strom TM.
Hum Mutat 31(11):E1851-60. 2010
25FOXP1
Foxp1 is an essential transcriptional regulator for the generation of quiescent naive T cells during thymocyte development.
Feng X, Ippolito GC, Tian L, Wiehagen K, Oh S, Sambandam A, Willen J, Bunte RM, Maika SD, Harriss JV, Caton AJ, Bhandoola A, Tucker PW, Hu H.
Blood 115(3):510-8. Epub 2009 Nov 12. 2010
26FOXP1, PITX3
FoxP1 promotes midbrain identity in embryonic stem cell-derived dopamine neurons by regulating Pitx3.
Konstantoulas CJ, Parmar M, Li M.
J Neurochem 113(4):836-47. doi: 10.1111/j.1471-4159.2010.06650.x. Epub 2010 Feb 19. 2010
27DEL3P14, FOXP1
A 785kb deletion of 3p14.1p13, including the FOXP1 gene, associated with speech delay, contractures, hypertonia and blepharophimosis.
Pariani MJ, Spencer A, Graham JM Jr, Rimoin DL.
Eur J Med Genet 52(2-3):123-7. Epub 2009 Mar 28. 2009
28FOXP1, FOXP2
Characterization of Foxp2-expressing cells in the developing spinal cord.
Morikawa Y, Hisaoka T, Senba E.
Neuroscience 162(4):1150-62. Epub 2009 May 20. 2009
29FOXP1
FOXP1 status in splenic marginal zone lymphoma: a fluorescence in situ hybridization and immunohistochemistry approach.
Baró C, Espinet B, Salido M, Colomo L, Luńo E, Florensa L, Ferrer A, Salar A, Campo E, Serrano S, Solé F.
Histol Histopathol 24(11):1399-404. 2009
30FOXP1
FOXP1 is an androgen-responsive transcription factor that negatively regulates androgen receptor signaling in prostate cancer cells.
Takayama K, Horie-Inoue K, Ikeda K, Urano T, Murakami K, Hayashizaki Y, Ouchi Y, Inoue S.
Biochem Biophys Res Commun 374(2):388-93. Epub 2008 Jul 18. 2008
31FOXP1, NCOR2
Cooperative regulation in development by SMRT and FOXP1.
Jepsen K, Gleiberman AS, Shi C, Simon DI, Rosenfeld MG.
Genes Dev 22(6):740-5. 2008
32MALT1, BCL10, FOXP1, MALTLY, MALTL
MALT1, BCL10 and FOXP1 in salivary gland mucosa-associated lymphoid tissue lymphomas.
Borovecki A, Korac P, Ventura RA, Perisa MM, Banham AH, Dominis M.
Pathol Int 57(1):47-51. 2007
33FOXP1, FOXP2
Foxp2 and Foxp1 cooperatively regulate lung and esophagus development.
Shu W, Lu MM, Zhang Y, Tucker PW, Zhou D, Morrisey EE.
Development 134(10):1991-2000. Epub 2007 Apr 11. 2007
34ETV6, FOXP1, PAX5, PML, ZNF521
Identification of PML as novel PAX5 fusion partner in childhood acute lymphoblastic leukaemia.
Nebral K, König M, Harder L, Siebert R, Haas OA, Strehl S.
Br J Haematol 139(2):269-74. 2007
35FOXP1, IGHA1
t(3;14)(p14;q32) results in aberrant expression of FOXP1 in a case of diffuse large B-cell lymphoma.
Fenton JA, Schuuring E, Barrans SL, Banham AH, Rollinson SJ, Morgan GJ, Jack AS, van Krieken JH, Kluin PM.
Genes Chromosomes Cancer 45(2):164-8. 2006
36FOXP1, IGHG1, MALT
T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma.
Streubel B, Vinatzer U, Lamprecht A, Raderer M, Chott A.
Leukemia 19(4):652-8. 2005
37FOXP1
The FOXP1 winged helix transcription factor is a novel candidate tumor suppressor gene on chromosome 3p.
Banham AH, Beasley N, Campo E, Fernandez PL, Fidler C, Gatter K, Jones M, Mason DY, Prime JE, Trougouboff P, Wood K, Cordell JL.
Cancer Res 61(24):8820-9. 2001