| 1 | FOXN1, WHN
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| Heterozygous FOXN1 Variants Cause Low TRECs and Severe T Cell Lymphopenia, Revealing a Crucial Role of FOXN1 in Supporting Early Thymopoiesis.
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| Bosticardo M, Yamazaki Y, Cowan J, Giardino G, Corsino C, Scalia G, Prencipe R, Ruffner M, Hill DA, Sakovich I, Yemialyanava I, Tam JS, Padem N, Elder ME, Sleasman JW, Perez E, Niebur H, Seroogy CM, Sharapova S, Gebbia J, Kleiner GI, Peake J, Abbott JK, Gelfand EW, Crestani E, Biggs C, Butte MJ, Hartog N, Hayward A, Chen K, Heimall J, Seeborg F, Bartnikas LM, Cooper MA, Pignata C, Bhandoola A, Notarangelo LD.
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| Am J Hum Genet 105(3):549-561. doi: 10.1016/j.ajhg.2019.07.014. Epub 2019 Aug 22.
2019
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| 2 | FOXN1, WHN
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| FOXN1 compound heterozygous mutations cause selective thymic hypoplasia in humans.
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| Du Q, Huynh LK, Coskun F, Molina E, King MA, Raj P, Khan S, Dozmorov I, Seroogy CM, Wysocki CA, Padron GT, Yates TR, Markert ML, de la Morena MT, van Oers NS.
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| J Clin Invest Clin Invest. 2019 Sep 30. pii: 127565. doi: 10.1172/JCI127565. [Epub ahead of print]
2019
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| 3 | FOXN1
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| FoxN1 mediates thymic cortex-medulla differentiation through modifying a developmental pattern based on epithelial tubulogenesis.
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| Muñoz JJ, Tobajas E, Juara S, Montero S, Zapata AG.
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| Histochem Cell Biol istochem Cell Biol. 2019 Sep 24. doi: 10.1007/s00418-019-01818-z. [Epub ahead of print]
2019
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| 4 | FOXN1
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| Identification of an Intronic Regulatory Element Necessary for Tissue-Specific Expression of Foxn1 in Thymic Epithelial Cells.
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| Larsen BM, Cowan JE, Wang Y, Tanaka Y, Zhao Y, Voisin B, Constantinides MG, Nagao K, Belkaid Y, Awasthi P, Takahama Y, Bhandoola A.
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| J Immunol 203(3):686-695. doi: 10.4049/jimmunol.1801540. Epub 2019 Jun 26.
2019
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| 5 | FOXN1, WHN
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| A Novel FOXN1 Variant Is Identified in Two Siblings with Nude Severe Combined Immunodeficiency.
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| Firtina S, Cipe F, Ng YY, Kiykim A, Ng OH, Sudutan T, Aydogmus C, Baris S, Ozturk G, Aydiner E, Ozen A, Sayitoglu M.
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| J Clin Immunol 39(2):144-147. doi: 10.1007/s10875-019-00615-6. Epub 2019 Mar 22. No abstract available.
2019
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| 6 | FOXN1
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| FoxN1-dependent thymic epithelial cells promote T-cell leukemia development.
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| Ghezzo MN, Fernandes MT, Pacheco-Leyva I, Rodrigues PM, Machado RS, Araújo MAS, Kalathur RK, Futschik ME, Alves NL, Dos Santos NR.
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| Carcinogenesis 39(12):1463-1476. doi: 10.1093/carcin/bgy127.
2018
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| 7 | FOXN1
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| Foxn1 and Mmp-9 expression in intact skin and during excisional wound repair in young, adult, and old C57Bl/6 mice.
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| Kopcewicz MM, Kur-Piotrowska A, Bukowska J, Gimble JM, Gawronska-Kozak B.
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| Wound Repair Regen 25(2):248-259. doi: 10.1111/wrr.12524. Epub 2017 Apr 19.
2017
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| 8 | FOXN1
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| Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells.
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| Žuklys S, Handel A, Zhanybekova S, Govani F, Keller M, Maio S, Mayer CE, Teh HY, Hafen K, Gallone G, Barthlott T, Ponting CP, Holländer GA.
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| Nat Immunol 17(10):1206-1215. doi: 10.1038/ni.3537. Epub 2016 Aug 22.
2016
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| 9 | FOXN1
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| Foxn1 Transcription Factor Regulates Wound Healing of Skin through Promoting Epithelial-Mesenchymal Transition.
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| Gawronska-Kozak B, Grabowska A, Kur-Piotrowska A, Kopcewicz M.
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| PLoS One 11(3):e0150635. doi: 10.1371/journal.pone.0150635. eCollection 2016.
2016
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| 10 | FOXN1
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| Changing in lipid profile induced by the mutation of Foxn1 gene: A lipidomic analysis of Nude mice skin.
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| Lanzini J, Dargère D, Regazzetti A, Tebani A, Laprévote O, Auzeil N.
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| Biochimie 118:234-43. doi: 10.1016/j.biochi.2015.09.029. Epub 2015 Sep 30.
2015
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| 11 | FOXN1, FOXN4
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| Conversion of the thymus into a bipotent lymphoid organ by replacement of FOXN1 with its paralog, FOXN4.
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| Swann JB, Weyn A, Nagakubo D, Bleul CC, Toyoda A, Happe C, Netuschil N, Hess I, Haas-Assenbaum A, Taniguchi Y, Schorpp M, Boehm T.
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| Cell Rep 8(4):1184-97. doi: 10.1016/j.celrep.2014.07.017. Epub 2014 Aug 14.
2014
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| 12 | FOXN1
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| Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice.
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| Ruan L, Zhang Z, Mu L, Burnley P, Wang L, Coder B, Zhuge Q, Su DM.
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| Cell Death Dis 5:e1457. doi: 10.1038/cddis.2014.432.
2014
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| 13 | FOXN1, WHN
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| Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice.
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| Ruan L, Zhang Z, Mu L, Burnley P, Wang L, Coder B, Zhuge Q, Su DM.
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| Cell Death Dis 5:e1457. doi: 10.1038/cddis.2014.432.
2014
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| 14 | FOXN1, RORA
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| The retinoid-related orphan receptor RORα promotes keratinocyte differentiation via FOXN1.
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| Dai J, Brooks Y, Lefort K, Getsios S, Dotto GP.
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| PLoS One 8(7):e70392. doi: 10.1371/journal.pone.0070392. Print 2013.
2013
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| 15 | FOXN1
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| Enhancing T lineage production in aged mice: a novel function of Foxn1 in the bone marrow niche.
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| Zook EC, Zhang S, Gerstein RM, Witte PL, Le PT.
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| J Immunol 191(11):5583-93. doi: 10.4049/jimmunol.1202278. Epub 2013 Nov 1.
2013
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| 16 | FOXN1
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| Deletion of FoxN1 in the thymic medullary epithelium reduces peripheral T cell responses to infection and mimics changes of aging.
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| Guo J, Feng Y, Barnes P, Huang FF, Idell S, Su DM, Shams H.
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| PLoS One 7(4):e34681. doi: 10.1371/journal.pone.0034681. Epub 2012 Apr 13.
2012
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| 17 | FOXN1
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| FOXN1 mutation abrogates prenatal T-cell development in humans.
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| Vigliano I, Gorrese M, Fusco A, Vitiello L, Amorosi S, Panico L, Ursini MV, Calcagno G, Racioppi L, Del Vecchio L, Pignata C.
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| J Med Genet 48(6):413-6. Epub 2011 Apr 19.
2011
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| 18 | FOXN1
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| Foxn1 regulates lineage progression in cortical and medullary thymic epithelial cells but is dispensable for medullary sublineage divergence.
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| Nowell CS, Bredenkamp N, Tetélin S, Jin X, Tischner C, Vaidya H, Sheridan JM, Stenhouse FH, Heussen R, Smith AJ, Blackburn CC.
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| PLoS Genet 7(11):e1002348. Epub 2011 Nov 3.
2011
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| 19 | FOXN1, MSX2
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| Msx2 and Foxn1 regulate nail homeostasis.
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| Cai J, Ma L.
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| Genesis 49(6):449-59. doi: 10.1002/dvg.20744. Epub 2011 May 31.
2011
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| 20 | FOXN1, HOXC13
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| The nude mutant gene Foxn1 is a HOXC13 regulatory target during hair follicle and nail differentiation.
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| Potter CS, Pruett ND, Kern MJ, Baybo MA, Godwin AR, Potter KA, Peterson RL, Sundberg JP, Awgulewitsch A.
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| J Invest Dermatol 131(4):828-37. Epub 2010 Dec 30.
2011
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| 21 | FOXN1
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| Postnatal tissue-specific disruption of transcription factor FoxN1 triggers acute thymic atrophy.
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| Cheng L, Guo J, Sun L, Fu J, Barnes PF, Metzger D, Chambon P, Oshima RG, Amagai T, Su DM.
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| J Biol Chem 285(8):5836-47. Epub 2009 Dec 2.
2010
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| 22 | FOXN1, WHN
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| Human clinical phenotype associated with FOXN1 mutations.
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| Pignata C, Fusco A, Amorosi S.
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| Adv Exp Med Biol 665:195-206. Review.
2009
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| 23 | FOXN1, MSX2
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| Genetic interplays between Msx2 and Foxn1 are required for Notch1 expression and hair shaft differentiation.
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| Cai J, Lee J, Kopan R, Ma L.
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| Dev Biol 326(2):420-30. Epub 2008 Dec 7.
2009
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| 24 | FOXN1, WHN
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| FOXN1 homozygous mutation associated with anencephaly and severe neural tube defect in human athymic Nude/SCID fetus.
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| Amorosi S, D'Armiento M, Calcagno G, Russo I, Adriani M, Christiano AM, Weiner L, Brissette JL, Pignata C.
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| Clin Genet 73(4):380-4. 2008
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| 25 | FOXN1
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| Dedicated epithelial recipient cells determine pigmentation patterns.
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| Weiner L, Han R, Scicchitano BM, Li J, Hasegawa K, Grossi M, Lee D, Brissette JL.
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| Cell 130(5):932-42. 2007
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| 26 | FOXN1
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| Foxn1 promotes keratinocyte differentiation by regulating the activity of protein kinase C.
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| Li J, Baxter RM, Weiner L, Goetinck PF, Calautti E, Brissette JL.
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| Differentiation 75(8):694-701. Epub 2007 Apr 25.
2007
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| 27 | FOXC2, LPDD,FOXC1, FOXE1, FOXE3, FOXL2, FOXN1, FOXP2, FOXP3, YNS
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| The establishment of a predictive mutational model of the forkhead domain through the analyses of FOXC2 missense mutations identified in patients with hereditary lymphedema with distichiasis.
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| Berry FB, Tamimi Y, Carle MV, Lehmann OJ, Walter MA.
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| Hum Mol Genet 14(18):2619-27. Epub 2005 Aug 4. 2005
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| 28 | FOXN1, WHN
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| Ancestral Founder Mutation of the Nude (FOXN1) Gene in Congenital Severe Combined Immunodeficiency Associated with Alopecia in Southern Italy Population.
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| Adriani M, Martinez-Mir A, Fusco F, Busiello R, Frank J, Telese S, Matrecano E, Ursini MV, Christiano AM, Pignata C.
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| Ann Hum Genet 68(Pt 3):265-8. 2004
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| 29 | FOXN1
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| A domain of Foxn1 required for crosstalk-dependent thymic epithelial cell differentiation.
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| Su DM, Navarre S, Oh WJ, Condie BG, Manley NR.
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| Nat Immunol 4(11):1128-35. Epub 2003 Oct 5. 2003
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| 30 | FOXN1
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| Exposing the human nude phenotype.
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| Frank J, et al.
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| Nature 398(6727):473-4. No abstract available 1999
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| 31 | FOXN1
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| Mapping of human WHN gene in a 17q11.2 YAC contig and identification of an intragenic STR.
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| Corrado L, et al.
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| Mol Cell Probes 13(3):199-202 1999
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| 32 | FOXN1
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| Characterization of mouse and human nude genes.
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| Schorpp M, Hofmann M, Dear TN, Boehm T.
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| Immunogenetics 46 : 509-515. 1997
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| 33 | SUPT6H, FOXN1, KCTD2, MDC1, KIAA0182
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| Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h.
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| Chiang PW, Wang S, Smithivas P, Song WJ, Ramamoorthy S, Hillman J, PuettS, Van Keuren ML, Crombez E, Kumar A, Glover TW, Miller DE, Tsai CH, BlackburnCC, Chen XN, Sun Z, Cheng JF, Korenberg JR, Kurnit DM.
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| Genomics 34(3):328-33. 1996
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