| 1 | FOXA1, SMARCD3
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| Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma.
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| Ferguson LP, Gatchalian J, McDermott ML, Nakamura M, Chambers K, Rajbhandari N, Lytle NK, Rosenthal SB, Hamilton M, Albini S, Wartenberg M, Zlobec I, Galván JA, Karamitopoulou E, Vavinskaya V, Wascher A, Lowy AM, Schürch CM, Puri PL, Bruneau BG, Hargreaves DC, Reya T.
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| Nat Commun. Jan 18;14(1):292. doi: 10.1038/s41467-023-35796-7. 2023
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| 2 | AR, FOXA1, GATA2, SEMA3C
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| Androgen receptor transcriptionally regulates semaphorin 3C in a GATA2-dependent manner.
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| Tam KJ, Dalal K, Hsing M, Cheng CW, Khosravi S, Yenki P, Tse C, Peacock JW, Sharma A, Chiang YT, Wang Y, Cherkasov A, Rennie PS, Gleave ME, Ong CJ.
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| Oncotarget 8(6):9617-9633. doi: 10.18632/oncotarget.14168.
2017
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| 3 | FOXA1, KMT2C
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| FOXA1 Directs H3K4 Monomethylation at Enhancers via Recruitment of the Methyltransferase MLL3.
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| Jozwik KM, Chernukhin I, Serandour AA, Nagarajan S, Carroll JS.
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| Cell Rep 17(10):2715-2723. doi: 10.1016/j.celrep.2016.11.028.
2016
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| 4 | CDKN1A, FOXA1, NR5A2
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| LRH-1 controls proliferation in breast tumor cells by regulating CDKN1A gene expression.
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| Bianco S, Jangal M, Garneau D, Gévry N.
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| Oncogene 34(34):4509-18. doi: 10.1038/onc.2014.382. Epub 2014 Dec 1.
2015
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| 5 | FOXA1, GATA3, KDM5B
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| Histone demethylase jumonji AT-rich interactive domain 1B (JARID1B) controls mammary gland development by regulating key developmental and lineage specification genes.
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| Zou MR, Cao J, Liu Z, Huh SJ, Polyak K, Yan Q.
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| J Biol Chem 289(25):17620-33. doi: 10.1074/jbc.M114.570853. Epub 2014 May 6.
2014
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| 6 | FOXA1, FOXA2
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| Foxa1 and Foxa2 regulate α-cell differentiation, glucagon biosynthesis, and secretion.
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| Heddad Masson M, Poisson C, Guérardel A, Mamin A, Philippe J, Gosmain Y.
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| Endocrinology 155(10):3781-92. doi: 10.1210/en.2013-1843. Epub 2014 Jul 24.
2014
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| 7 | FOXA1
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| FOXA1 mediates p16(INK4a) activation during cellular senescence.
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| Li Q, Zhang Y, Fu J, Han L, Xue L, Lv C, Wang P, Li G, Tong T.
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| EMBO J 32(6):858-73. doi: 10.1038/emboj.2013.35. Epub 2013 Feb 26.
2013
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| 8 | FOXA1
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| FOXA1 mutations in hormone-dependent cancers.
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| Robinson JL, Holmes KA, Carroll JS.
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| Front Oncol 3:20. doi: 10.3389/fonc.2013.00020. Epub 2013 Feb 14.
2013
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| 9 | FOXA1, FOXA2
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| Foxa1 and foxa2 are required for the maintenance of dopaminergic properties in ventral midbrain neurons at late embryonic stages.
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| Stott SR, Metzakopian E, Lin W, Kaestner KH, Hen R, Ang SL.
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| J Neurosci 33(18):8022-34. doi: 10.1523/JNEUROSCI.4774-12.2013.
2013
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| 10 | FOXA1, FOXA2
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| Foxa1 and Foxa2 are required for formation of the intervertebral discs.
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| Maier JA, Lo Y, Harfe BD.
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| PLoS One 8(1):e55528. doi: 10.1371/journal.pone.0055528. Epub 2013 Jan 31.
2013
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| 11 | AHR, CCNG2, FOXA1
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| FOXA1 is essential for aryl hydrocarbon receptor-dependent regulation of cyclin G2.
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| Ahmed S, Al-Saigh S, Matthews J.
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| Mol Cancer Res 10(5):636-48.
2012
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| 12 | FOXA1
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| Foxa1 reduces lipid accumulation in human hepatocytes and is down-regulated in nonalcoholic fatty liver.
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| Moya M, Benet M, Guzmán C, Tolosa L, García-Monzón C, Pareja E, Castell JV, Jover R.
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| PLoS One 7(1):e30014. doi: 10.1371/journal.pone.0030014. Epub 2012 Jan 6.
2012
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| 13 | FOXA1
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| FOXA1: a transcription factor with parallel functions in development and cancer.
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| Bernardo GM, Keri RA.
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| Biosci Rep 32(2):113-30. doi: 10.1042/BSR20110046. Review.
2012
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| 14 | FOXA1, NR3C1
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| FoxA1 and glucocorticoid receptor crosstalk via histone H4K16 acetylation at a hormone regulated enhancer.
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| Belikov S, Holmqvist PH, Astrand C, Wrange Ö.
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| Exp Cell Res 318(1):61-74. doi: 10.1016/j.yexcr.2011.09.016. Epub 2011 Oct 6.
2012
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| 15 | FOXA1
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| FOXA1 and breast cancer risk.
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| Meyer KB, Carroll JS.
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| Nat Genet 44(11):1176-7. doi: 10.1038/ng.2449.
2012
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| 16 | FOXA1, NKX3-1, RAB3B
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| Integration of regulatory networks by NKX3-1 promotes androgen-dependent prostate cancer survival.
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| Tan PY, Chang CW, Chng KR, Wansa KD, Sung WK, Cheung E.
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| Mol Cell Biol 32(2):399-414. doi: 10.1128/MCB.05958-11. Epub 2011 Nov 14.
2012
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| 17 | FOXA1, MED12, SPOP
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| Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer.
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| Barbieri CE, Baca SC, Lawrence MS, Demichelis F, Blattner M, Theurillat JP, White TA, Stojanov P, Van Allen E, Stransky N, Nickerson E, Chae SS, Boysen G, Auclair D, Onofrio RC, Park K, Kitabayashi N, MacDonald TY, Sheikh K, Vuong T, Guiducci C, Cibulskis K, Sivachenko A, Carter SL, Saksena G, Voet D, Hussain WM, Ramos AH, Winckler W, Redman MC, Ardlie K, Tewari AK, Mosquera JM, Rupp N, Wild PJ, Moch H, Morrissey C, Nelson PS, Kantoff PW, Gabriel SB, Golub TR, Meyerson M, Lander ES, Getz G, Rubin MA, Garraway LA.
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| Nat Genet 44(6):685-9. doi: 10.1038/ng.2279.
2012
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| 18 | BEST2, FOXA1, SLC12A2
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| Forkhead transcription factor FoxA1 regulates sweat secretion through Bestrophin 2 anion channel and Na-K-Cl cotransporter 1
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| Cui CY, Childress V, Piao Y, Michel M, Johnson AA, Kunisada M, Ko MS, Kaestner KH, Marmorstein AD, Schlessinger D.
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| Proc Natl Acad Sci U S A an 24;109(4):1199-203. doi: 10.1073/pnas.1117213109. Epub 2012 Jan 5 2012
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| 19 | CTCF, FOXA1
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| FOXA1 is a key determinant of estrogen receptor function and endocrine response.
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| Hurtado A, Holmes KA, Ross-Innes CS, Schmidt D, Carroll JS.
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| Nat Genet 43(1):27-33. Epub 2010 Dec 12.
2011
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| 20 | CEBPB, FOXA1
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| Forkhead transcription factor Foxa1 is a novel target gene of C/EBPβ and suppresses the early phase of adipogenesis.
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| Fujimori K, Amano F.
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| Gene 473(2):150-6. Epub 2010 Dec 15.
2011
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| 21 | FOXA1
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| FOXA1: master of steroid receptor function in cancer.
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| Augello MA, Hickey TE, Knudsen KE.
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| EMBO J 30(19):3885-94. doi: 10.1038/emboj.2011.340. Review.
2011
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| 22 | FOXA1
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| Dual role of FoxA1 in androgen receptor binding to chromatin, androgen signalling and prostate cancer.
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| Sahu B, Laakso M, Ovaska K, Mirtti T, Lundin J, Rannikko A, Sankila A, Turunen JP, Lundin M, Konsti J, Vesterinen T, Nordling S, Kallioniemi O, Hautaniemi S, Jänne OA.
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| EMBO J 30(19):3962-76. doi: 10.1038/emboj.2011.328.
2011
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| 23 | FOXA1, HDAC7, RPRM
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| Histone deacetylase 7 and FoxA1 in estrogen-mediated repression of RPRM.
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| Malik S, Jiang S, Garee JP, Verdin E, Lee AV, O'Malley BW, Zhang M, Belaguli NS, Oesterreich S.
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| Mol Cell Biol 30(2):399-412. Epub 2009 Nov 16.PMID: 19917725 2010
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| 24 | FOXA1, HOXB13
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| A FOXA1-binding enhancer regulates Hoxb13 expression in the prostate gland.
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| McMullin RP, Dobi A, Mutton LN, Orosz A, Maheshwari S, Shashikant CS, Bieberich CJ.
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| Proc Natl Acad Sci U S A 107(1):98-103. Epub 2009 Dec 14.PMID: 20018680 2010
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| 25 | FOXA1, FOXA2, FOXA3, FOXC1, FOXC2, FOXO1, FOXO3, FOXO4, FOXP2, FOXP3
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| The evolution of Fox genes and their role in development and disease.
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| Hannenhalli S, Kaestner KH.
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| Nat Rev Genet 10(4):233-40. Review. 2009
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| 26 | FOXA1, HSPA1A
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| Up-regulation of the HSP72 by Foxa1 in MCF-7 human breast cancer cell line.
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| Song L, Xu Z, Zhang C, Qiao X, Huang C.
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| Biochem Biophys Res Commun 386(1):30-4. Epub 2009 May 30.
2009
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| 27 | FOXA1, USF2
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| Upstream stimulatory factor 2, a novel FoxA1-interacting protein, is involved in prostate-specific gene expression.
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| Sun Q, Yu X, Degraff DJ, Matusik RJ.
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| Mol Endocrinol 23(12):2038-47. Epub 2009 Oct 21.PMID: 19846536 2009
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| 28 | FOXA1, FOXA2, MUC2
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| Forkhead box transcription factors Foxa1 and Foxa2 are important regulators of Muc2 mucin expression in intestinal epithelial cells.
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| van der Sluis M, Vincent A, Bouma J, Male AK, van Goudoever JB, Renes IB, Van Seuningen I.
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| Biochem Biophys Res Commun 369(4):1108-13. Epub 2008 Mar 10. 2008
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| 29 | FOXA1, FOXA2, PDX1
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| Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development.
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| Gao N, LeLay J, Vatamaniuk MZ, Rieck S, Friedman JR, Kaestner KH.
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| Genes Dev 22(24):3435-48.
2008
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| 30 | FOXA1
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| Forkhead-box A1 (FOXA1) expression in breast cancer and its prognostic significance.
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| Habashy HO, Powe DG, Rakha EA, Ball G, Paish C, Gee J, Nicholson RI, Ellis IO.
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| Eur J Cancer 44(11):1541-51. Epub 2008 Jun 4.
2008
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| 31 | FOXA1, NKX2-1
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| Physical and functional interactions between homeodomain NKX2.1 and winged helix/forkhead FOXA1 in lung epithelial cells.
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| Minoo P, Hu L, Xing Y, Zhu NL, Chen H, Li M, Borok Z, Li C.
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| Mol Cell Biol 27(6):2155-65. Epub 2007 Jan 12.
2007
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| 32 | FOXA1
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| FOXA1 expression in breast cancer--correlation with luminal subtype A and survival.
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| Badve S, Turbin D, Thorat MA, Morimiya A, Nielsen TO, Perou CM, Dunn S, Huntsman DG, Nakshatri H.
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| Clin Cancer Res 13(15 Pt 1):4415-21.
2007
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| 33 | FOXA1
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| FOXA1 as a therapeutic target for breast cancer.
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| Nakshatri H, Badve S.
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| Expert Opin Ther Targets 11(4):507-14. Review.
2007
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| 34 | FOXA1, FOXA2
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| Foxa1 and Foxa2 regulate multiple phases of midbrain dopaminergic neuron development in a dosage-dependent manner.
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| Ferri AL, Lin W, Mavromatakis YE, Wang JC, Sasaki H, Whitsett JA, Ang SL.
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| Development 134(15):2761-9. Epub 2007 Jun 27.
2007
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| 35 | FOXA1, FOXA2
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| The initiation of liver development is dependent on Foxa transcription factors.
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| Lee CS, Friedman JR, Fulmer JT, Kaestner KH.
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| Nature 435(7044):944-7. 2005
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| 36 | C21orf129, ESR1, FOXA1
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| Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.
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| Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M.
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| Cell 122(1):33-43. 2005
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| 37 | TRPS1, IRX5, CYP4Z1, FSIP1, FOXA1, ANKRD30A
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| The gene associated with trichorhinophalangeal syndrome in humans is overexpressed in breast cancer.
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| Radvanyi L, Singh-Sandhu D, Gallichan S, Lovitt C, Pedyczak A, Mallo G, Gish K, Kwok K, Hanna W, Zubovits J, Armes J, Venter D, Hakimi J, Shortreed J, Donovan M, Parrington M, Dunn P, Oomen R, Tartaglia J, Berinstein NL.
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| Proc Natl Acad Sci U S A 102(31):11005-10. Epub 2005 Jul 25. 2005
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| 38 | FOXA1, ESR1, TFF1
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| From the Cover: Location analysis of estrogen receptor {alpha} target promoters reveals that FOXA1 defines a domain of the estrogen response.
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| Laganiere J, Deblois G, Lefebvre C, Bataille AR, Robert F, Giguere V.
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| Proc Natl Acad Sci U S A 102(33):11651-6. Epub 2005 Aug 8. 2005
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| 39 | FOXA1, GCG, FOXA2
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| Characterization of a novel Foxa (hepatocyte nuclear factor-3) site in the glucagon promoter that is conserved between rodents and humans.
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| Sharma SK, Leinemann U, Ratke R, Oetjen E, Blume R, Dickel C, Knepel W.
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| Biochem J 389(Pt 3):831-41. 2005
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| 40 | NOXO1, FOXO1, FOXA1
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| NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain.
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| Cheng G, Lambeth JD.
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| J Biol Chem 279(6):4737-42. Epub 2003 Nov 14. 2004
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| 41 | FOXA1, FOXA2, FOXA3
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| The Human HNF-3 Genes: Cloning, Partial Sequence and Mutation Screening in Patients with Impaired Glucose Homeostasis.
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| Navas MA, Vaisse C, Boger S, Heimesaat M, Kollee LA, Stoffel M.
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| Hum Hered 50(6):370-381. 2000
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| 42 | FOXA1, FOXA2, FOXA3
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| Assignment of the human genes for hepatocyte nuclear factor 3-alpha, -beta, and -gamma (HNF3A, HNF3B, HNF3G) to 14q12-q13, 20p11, and 19q13.2-q13.4.
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| Mincheva A, et al.
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| Genomics 39 : 417-419. 1997
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| 43 | FOXA1, FOXA2, FOXA3, HNF4A, HNF4G, ONECUT1
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| Pancreatic islet expression studies and polymorphic DNA markers in the genes encoding hepatocyte nuclear factor-3alpha, -3beta, -3gamma, -4gamma, and -6.
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| Vaisse C, Kim J, Espinosa R 3rd, Le Beau MM, Stoffel M.
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| Diabetes 46(8):1364-7. 1997
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| 44 | FOXA1, FOXA2, FOXA3
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| In vivo protein-DNA interactions on a glucocorticoid response unit of a liver-specific gene: hormone-induced transcription factor binding to constitutively open chromatin.
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| Zimmermann PL, et al.
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| DNA Cell Biol 16(6):713-23 1997
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| 45 | FOXA1, FOXA2, FOXM1
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| Hepatocyte nuclear factor 3/fork head homolog 11 is expressed in proliferating epithelial and mesenchymal cells of embryonic and adult tissues.
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| Ye H, Kelly TF, Samadani U, Lim L, Rubio S, Overdier DG, Roebuck KA, Costa RH.
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| Mol Cell Biol 17(3):1626-41. 1997
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| 46 | FOXA1
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| Molecular cloning of the forkhead transcription factor HNF-3 alpha from a human pulmonary adenocarcinoma cell line.
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| Bingle CD, Gowan S.
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| Biochim Biophys Acta 1307(1):17-20. 1996
|