1 | FNTA, FNTB
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| Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit.
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| Hagemann A, Müller G, Manthey I, Bachmann HS.
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| FEBS Lett 591(21):3637-3648. doi: 10.1002/1873-3468.12862. Epub 2017 Oct 11.
2017
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2 | FNTB
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| Farnesyltransferase regulates neutrophil recruitment and tissue damage in acute pancreatitis.
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| Merza M, Awla D, Hwaiz R, Rahman M, Appelros S, Abdulla A, Regner S, Thorlacius H.
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| Pancreas 43(3):427-35. doi: 10.1097/MPA.0000000000000041.
2014
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3 | FNTB
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| Expansion of protein farnesyltransferase specificity using "tunable" active site interactions: development of bioengineered prenylation pathways.
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| Hougland JL, Gangopadhyay SA, Fierke CA.
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| J Biol Chem 287(45):38090-100. doi: 10.1074/jbc.M112.404954. Epub 2012 Sep 19.
2012
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4 | FNTB, PGGT1B
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| Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases.
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| Yang SH, Chang SY, Tu Y, Lawson GW, Bergo MO, Fong LG, Young SG.
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| J Lipid Res 53(1):77-86. doi: 10.1194/jlr.M021220. Epub 2011 Oct 28.
2012
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5 | FNTB, PGGT1B
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| Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.
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| Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG.
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| Hum Mol Genet 19(8):1603-17. Epub 2010 Jan 27.
2010
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6 | FNTA, FNTB, HDAC6
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| The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner.
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| Zhou J, Vos CC, Gjyrezi A, Yoshida M, Khuri FR, Tamanoi F, Giannakakou P.
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| J Biol Chem 284(15):9648-55. Epub 2009 Feb 18. 2009
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7 | FNTB
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| Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development.
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| Mijimolle N, Velasco J, Dubus P, Guerra C, Weinbaum CA, Casey PJ, Campuzano V, Barbacid M.
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| Cancer Cell 7(4):313-24.
2005
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8 | FNTB
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| Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.
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| deSolms SJ, Ciccarone TM, MacTough SC, Shaw AW, Buser CA, Ellis-Hutchings M, Fernandes C, Hamilton KA, Huber HE, Kohl NE, Lobell RB, Robinson RG, Tsou NN, Walsh ES, Graham SL, Beese LS, Taylor JS.
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| J Med Chem 46(14):2973-84.
2003
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9 | FNTB
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| Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
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| Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.
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| Cancer Res 61(24):8758-68.
2001
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10 | GBP1, FNTB
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| Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
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| Prakash B, Praefcke GJ, Renault L, Wittinghofer A, Herrmann C.
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| Nature 403(6769):567-71. 2000
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11 | FNTAL1, FNTAL2, FNTBL1, FNTA, FNTB
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| cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences.
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| Andres DA, et al.
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| Genomics 18(1):105-12. 1993
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