Citations for
1FNTA, FNTB
Exploring the putative self-binding property of the human farnesyltransferase alpha-subunit.
Hagemann A, Müller G, Manthey I, Bachmann HS.
FEBS Lett 591(21):3637-3648. doi: 10.1002/1873-3468.12862. Epub 2017 Oct 11. 2017
2FNTB
Farnesyltransferase regulates neutrophil recruitment and tissue damage in acute pancreatitis.
Merza M, Awla D, Hwaiz R, Rahman M, Appelros S, Abdulla A, Regner S, Thorlacius H.
Pancreas 43(3):427-35. doi: 10.1097/MPA.0000000000000041. 2014
3FNTB
Expansion of protein farnesyltransferase specificity using "tunable" active site interactions: development of bioengineered prenylation pathways.
Hougland JL, Gangopadhyay SA, Fierke CA.
J Biol Chem 287(45):38090-100. doi: 10.1074/jbc.M112.404954. Epub 2012 Sep 19. 2012
4FNTB, PGGT1B
Severe hepatocellular disease in mice lacking one or both CaaX prenyltransferases.
Yang SH, Chang SY, Tu Y, Lawson GW, Bergo MO, Fong LG, Young SG.
J Lipid Res 53(1):77-86. doi: 10.1194/jlr.M021220. Epub 2011 Oct 28. 2012
5FNTB, PGGT1B
Genetic studies on the functional relevance of the protein prenyltransferases in skin keratinocytes.
Lee R, Chang SY, Trinh H, Tu Y, White AC, Davies BS, Bergo MO, Fong LG, Lowry WE, Young SG.
Hum Mol Genet 19(8):1603-17. Epub 2010 Jan 27. 2010
6FNTA, FNTB, HDAC6
The protein farnesyltransferase regulates HDAC6 activity in a microtubule-dependent manner.
Zhou J, Vos CC, Gjyrezi A, Yoshida M, Khuri FR, Tamanoi F, Giannakakou P.
J Biol Chem 284(15):9648-55. Epub 2009 Feb 18. 2009
7FNTB
Protein farnesyltransferase in embryogenesis, adult homeostasis, and tumor development.
Mijimolle N, Velasco J, Dubus P, Guerra C, Weinbaum CA, Casey PJ, Campuzano V, Barbacid M.
Cancer Cell 7(4):313-24. 2005
8FNTB
Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.
deSolms SJ, Ciccarone TM, MacTough SC, Shaw AW, Buser CA, Ellis-Hutchings M, Fernandes C, Hamilton KA, Huber HE, Kohl NE, Lobell RB, Robinson RG, Tsou NN, Walsh ES, Graham SL, Beese LS, Taylor JS.
J Med Chem 46(14):2973-84. 2003
9FNTB
Evaluation of farnesyl:protein transferase and geranylgeranyl:protein transferase inhibitor combinations in preclinical models.
Lobell RB, Omer CA, Abrams MT, Bhimnathwala HG, Brucker MJ, Buser CA, Davide JP, deSolms SJ, Dinsmore CJ, Ellis-Hutchings MS, Kral AM, Liu D, Lumma WC, Machotka SV, Rands E, Williams TM, Graham SL, Hartman GD, Oliff AI, Heimbrook DC, Kohl NE.
Cancer Res 61(24):8758-68. 2001
10GBP1, FNTB
Structure of human guanylate-binding protein 1 representing a unique class of GTP-binding proteins.
Prakash B, Praefcke GJ, Renault L, Wittinghofer A, Herrmann C.
Nature 403(6769):567-71. 2000
11FNTAL1, FNTAL2, FNTBL1, FNTA, FNTB
cDNA cloning of the two subunits of human CAAX farnesyltransferase and chromosomal mapping of FNTA and FNTB loci and related sequences.
Andres DA, et al.
Genomics 18(1):105-12. 1993