| 1 | FNDC5, MAPK14, PRKAA1
|
| Irisin, a Novel Myokine, Regulates Glucose Uptake in Skeletal Muscle Cells via AMPK.
|
| Lee HJ, Lee JO, Kim N, Kim JK, Kim HI, Lee YW, Kim SJ, Choi JI, Oh Y, Kim JH, Suyeon-Hwang, Park SH, Kim HS.
|
| Mol Endocrinol 29(6):873-81. doi: 10.1210/me.2014-1353. Epub 2015 Mar 31.
2015
|
| 2 | FGF21, FNDC5
|
| Irisin and FGF21 Are Cold-Induced Endocrine Activators of Brown Fat Function in Humans.
|
| Lee P, Linderman JD, Smith S, Brychta RJ, Wang J, Idelson C, Perron RM, Werner CD, Phan GQ, Kammula US, Kebebew E, Pacak K, Chen KY, Celi FS.
|
| Cell Metab 19(2):302-9. doi: 10.1016/j.cmet.2013.12.017.
2014
|
| 3 | FNDC5
|
| risin as a muscle-derived hormone stimulating thermogenesis - A critical update.
|
| Hofmann T, Elbelt U, Stengel A.
|
| Peptides 54C:89-100. doi: 10.1016/j.peptides.2014.01.016. [Epub ahead of print] Review.
2014
|
| 4 | FNDC5
|
| Effects of obesity, diabetes and exercise on Fndc5 gene expression and irisin release in human skeletal muscle and adipose tissue: in vivo and in vitro studies.
|
| Kurdiova T, Balaz M, Vician M, Maderova D, Vlcek M, Valkovic L, Srbecky M, Imrich R, Kyselovicova O, Belan V, Jelok I, Wolfrum C, Klimes I, Krssak M, Zemkova E, Gasperikova D, Ukropec J, Ukropcova B.
|
| J Physiol 592(Pt 5):1091-107. doi: 10.1113/jphysiol.2013.264655. Epub 2013 Dec 2.
2014
|
| 5 | FNDC5, PPARGC1A
|
| Exercise induces hippocampal BDNF through a PGC-1α/FNDC5 pathway.
|
| Wrann CD, White JP, Salogiannnis J, Laznik-Bogoslavski D, Wu J, Ma D, Lin JD, Greenberg ME, Spiegelman BM.
|
| Cell Metab 18(5):649-59. doi: 10.1016/j.cmet.2013.09.008. Epub 2013 Oct 10.
2013
|
| 6 | FNDC5
|
| Decrease in irisin in patients with chronic kidney disease.
|
| Wen MS, Wang CY, Lin SL, Hung KC.
|
| PLoS One 8(5):e64025. doi: 10.1371/journal.pone.0064025. Print 2013.
2013
|
| 7 | FNDC5
|
| Common genetic variation in the human FNDC5 locus, encoding the novel muscle-derived 'browning' factor irisin, determines insulin sensitivity.
|
| Staiger H, Böhm A, Scheler M, Berti L, Machann J, Schick F, Machicao F, Fritsche A, Stefan N, Weigert C, Krook A, Häring HU, de Angelis MH.
|
| PLoS One 8(4):e61903. doi: 10.1371/journal.pone.0061903. Print 2013.
2013
|
| 8 | FNDC5
|
| FNDC5/irisin is not only a myokine but also an adipokine.
|
| Roca-Rivada A, Castelao C, Senin LL, Landrove MO, Baltar J, Belén Crujeiras A, Seoane LM, Casanueva FF, Pardo M.
|
| PLoS One 8(4):e60563. doi: 10.1371/journal.pone.0060563. Print 2013.
2013
|
| 9 | FNDC5
|
| Irisin is expressed and produced by human muscle and adipose tissue in association with obesity and insulin resistance.
|
| Moreno-Navarrete JM, Ortega F, Serrano M, Guerra E, Pardo G, Tinahones F, Ricart W, Fernández-Real JM.
|
| J Clin Endocrinol Metab 98(4):E769-78. doi: 10.1210/jc.2012-2749. Epub 2013 Feb 22.
2013
|
| 10 | FNDC5, PPARA, PPARGC1A
|
| A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis.
|
| Boström P, Wu J, Jedrychowski MP, Korde A, Ye L, Lo JC, Rasbach KA, Boström EA, Choi JH, Long JZ, Kajimura S, Zingaretti MC, Vind BF, Tu H, Cinti S, Højlund K, Gygi SP, Spiegelman BM.
|
| Nature 481(7382):463-8. doi: 10.1038/nature10777.
2012
|
| 11 | FNDC5
|
| FNDC5 and irisin in humans: I. Predictors of circulating concentrations in serum and plasma and II. mRNA expression and circulating concentrations in response to weight loss and exercise.
|
| Huh JY, Panagiotou G, Mougios V, Brinkoetter M, Vamvini MT, Schneider BE, Mantzoros CS.
|
| Metabolism 61(12):1725-38. doi: 10.1016/j.metabol.2012.09.002. Epub 2012 Sep 25.
2012
|
| 12 | FNDC4, FNDC5
|
| Frcp1 and Frcp2, two novel fibronectin type III repeat containing genes.
|
| Teufel A, Malik N, Mukhopadhyay M, Westphal H.
|
| Gene 297(1-2):79-83. 2002
|