| 1 | FLRT2, FLRT3
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| FLRT2 and FLRT3 Cooperate in Maintaining the Tangential Migratory Streams of Cortical Interneurons during Development.
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| Fleitas C, Marfull-Oromí P, Chauhan D, Del Toro D, Peguera B, Zammou B, Rocandio D, Klein R, Espinet C, Egea J.
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| J Neurosci. Sep 1;41(35):7350-7362. doi: 10.1523/JNEUROSCI.0380-20.2021. Epub 2021 Jul 23. 2021
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| 2 | ADGRL3, FLRT3, TENM2
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| Alternative splicing controls teneurin-latrophilin interaction and synapse specificity by a shape-shifting mechanism
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| Li J, Xie Y, Cornelius S, Jiang X, Sando R, Kordon SP, Pan M, Leon K, Südhof TC, Zhao M, Araç D.
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| Nat Commun. May 1;11(1):2140. doi: 10.1038/s41467-020-16029-7. 2020
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| 3 | FLRT3, UNC5B
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| Axon Guidance-Related Factor FLRT3 Regulates VEGF-Signaling and Endothelial Cell Function.
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| Jauhiainen S, Laakkonen JP, Ketola K, Toivanen PI, Nieminen T, Ninchoji T, Levonen AL, Kaikkonen MU, Ylä-Herttuala S.
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| Front Physiol. Mar 12;10:224. doi: 10.3389/fphys.2019.00224. 2019
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| 4 | FLRT3
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| Increased Expression of Fibronectin Leucine-Rich Transmembrane Protein 3 in the Dorsal Root Ganglion Induces Neuropathic Pain in Rats
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| Yamada M, Fujita Y, Hayano Y, Hayakawa H, Baba K, Mochizuki H, Yamashita T.
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| J Neurosci. Sep 18;39(38):7615-7627. doi: 10.1523/JNEUROSCI.0295-19.2019. Epub 2019 Jul 25 2019
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| 5 | FGF17, FLRT3, HH20, HH21
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| New genetic findings in a large cohort of congenital hypogonadotropic hypogonadism.
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| Amato LGL, Montenegro LR, Lerario AM, Jorge AAL, Guerra Junior G, Schnoll C, Renck AC, Trarbach EB, Costa EMF, Mendonca BB, Latronico AC, Silveira LFG.
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| Eur J Endocrinol. Aug 1;181(2):103-119. doi: 10.1530/EJE-18-0764. 2019
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| 6 | FGF8, FLRT3, TBX2
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| Tbx2 regulates anterior neural specification by repressing FGF signaling pathway.
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| Cho GS, Park DS, Choi SC, Han JK.
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| Dev Biol. Jan 15;421(2):183-193. doi: 10.1016/j.ydbio.2016.11.020. Epub 2016 Nov 30 2017
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| 7 | ADGRL3, FLRT3, UNC5A, UNC5B, UNC5C, UNC5D
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| Structural Basis of Latrophilin-FLRT-UNC5 Interaction in Cell Adhesion.
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| Lu YC, Nazarko OV, Sando R 3rd, Salzman GS, Li NS, Südhof TC, Araç D.
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| Structure. Sep 1;23(9):1678-1691. doi: 10.1016/j.str.2015.06.024. Epub 2015 Jul 30. 2015
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| 8 | ADGRL3, FLRT3
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| Structural and Mechanistic Insights into the Latrophilin3-FLRT3 Complex that Mediates Glutamatergic Synapse Development
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| Ranaivoson FM, Liu Q, Martini F, Bergami F, von Daake S, Li S, Lee D, Demeler B, Hendrickson WA, Comoletti D.
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| Structure. Sep 1;23(9):1665-1677. doi: 10.1016/j.str.2015.06.022. Epub 2015 Jul 30. 2015
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| 9 | DUSP6, FGF17, FLRT3, HH20, HH21, IL17RD, SPRY4
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| Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 Are Identified in Individuals with Congenital Hypogonadotropic Hypogonadism.
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| Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF Jr, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N.
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| Am J Hum Genet 92(5):725-43. doi: 10.1016/j.ajhg.2013.04.008. 2013
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| 10 | FLRT3
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| BMP signal attenuates FGF pathway in anteroposterior neural patterning.
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| Cho GS, Choi SC, Han JK.
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| Biochem Biophys Res Commun. May 10;434(3):509-15. doi: 10.1016/j.bbrc.2013.03.105. Epub 2013 Apr 11. 2013
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| 11 | FLRT3, HH21
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| Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism
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| Miraoui H, Dwyer AA, Sykiotis GP, Plummer L, Chung W, Feng B, Beenken A, Clarke J, Pers TH, Dworzynski P, Keefe K, Niedziela M, Raivio T, Crowley WF Jr, Seminara SB, Quinton R, Hughes VA, Kumanov P, Young J, Yialamas MA, Hall JE, Van Vliet G, Chanoine JP, Rubenstein J, Mohammadi M, Tsai PS, Sidis Y, Lage K, Pitteloud N.
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| Am J Hum Genet. May 2;92(5):725-43. doi: 10.1016/j.ajhg.2013.04.008. 2012
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| 12 | FLRT2, FLRT3
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| The fibronectin leucine-rich repeat transmembrane protein Flrt2 is required in the epicardium to promote heart morphogenesis.
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| Müller PS, Schulz R, Maretto S, Costello I, Srinivas S, Bikoff E, Robertson E.
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| Development 138(7):1297-308. Epub 2011 Feb 24.
2011
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| 13 | FLRT2, FLRT3, UNC5B, UNC5D
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| FLRT2 and FLRT3 act as repulsive guidance cues for Unc5-positive neurons.
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| Yamagishi S, Hampel F, Hata K, Del Toro D, Schwark M, Kvachnina E, Bastmeyer M, Yamashita T, Tarabykin V, Klein R, Egea J.
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| EMBO J 30(14):2920-33. doi: 10.1038/emboj.2011.189.
2011
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| 14 | FGFR1, FLRT1, FLRT2, FLRT3
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| Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling.
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| Wheldon LM, Haines BP, Rajappa R, Mason I, Rigby PW, Heath JK.
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| PLoS One 5(4):e10264. 2010
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| 15 | FLRT2, FLRT3
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| Flrt2 and Flrt3 have overlapping and non-overlapping expression during craniofacial development.
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| Gong SG, Mai S, Chung K, Wei K.
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| Gene Expr Patterns 9(7):497-502. Epub 2009 Jul 25.
2009
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| 16 | FLRT3, PCDH8
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| A protocadherin-cadherin-FLRT3 complex controls cell adhesion and morphogenesis.
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| Chen X, Koh E, Yoder M, Gumbiner BM.
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| PLoS One 4(12):e8411.
2009
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| 17 | FLRT3, UNC5B
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| Unc5B interacts with FLRT3 and Rnd1 to modulate cell adhesion in Xenopus embryos.
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| Karaulanov E, Böttcher RT, Stannek P, Wu W, Rau M, Ogata S, Cho KW, Niehrs C.
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| PLoS One 4(5):e5742.
2009
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| 18 | FLRT1, FLRT2, FLRT3
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| Regulated expression of FLRT genes implies a functional role in the regulation of FGF signalling during mouse development.
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| Haines BP, Wheldon LM, Summerbell D, Heath JK, Rigby PW.
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| Dev Biol 297(1):14-25. Epub 2006 Apr 21.
2006
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| 19 | FLRT1, FLRT2, FLRT3
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| A role for fibronectin-leucine-rich transmembrane cell-surface proteins in homotypic cell adhesion.
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| Karaulanov EE, Böttcher RT, Niehrs C.
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| EMBO Rep 7(3):283-90. Epub 2006 Jan 20.
2006
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| 20 | FLRT3
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| FLRT3, a cell surface molecule containing LRR repeats and a FNIII domain, promotes neurite outgrowth.
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| Tsuji L, Yamashita T, Kubo T, Madura T, Tanaka H, Hosokawa K, Tohyama M.
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| Biochem Biophys Res Commun 313(4):1086-91. 2004
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| 21 | FLRT3
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| FLRT3 is expressed in sensory neurons after peripheral nerve injury and regulates neurite outgrowth.
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| Robinson M, Parsons Perez MC, Tebar L, Palmer J, Patel A, Marks D, Sheasby A, De Felipe C, Coffin R, Livesey FJ, Hunt SP.
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| Mol Cell Neurosci 27(2):202-14. 2004
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| 22 | FLRT1, FLRT2, FLRT3
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| Identification of FLRT1, FLRT2, and FLRT3: A novel family of transmembrane leucine-rich repeat proteins.
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| Lacy SE, Bonnemann CG, Buzney EA, Kunkel LM.
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| Genomics 62(3):417-26 1999
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