1 | FLOT2, RAB11A, SNX4
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| Reggies/flotillins interact with Rab11a and SNX4 at the tubulovesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking.
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| Solis GP, Hülsbusch N, Radon Y, Katanaev VL, Plattner H, Stuermer CA.
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| Mol Biol Cell 24(17):2689-702. doi: 10.1091/mbc.E12-12-0854. Epub 2013 Jul 3.
2013
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2 | FLOT2
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| Flotillin-2 is associated with breast cancer progression and poor survival outcomes.
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| Wang X, Yang Q, Guo L, Li XH, Zhao XH, Song LB, Lin HX.
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| J Transl Med 11:190. doi: 10.1186/1479-5876-11-190.
2013
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3 | FLOT1, FLOT2
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| Expression of flotillins in the human placenta: potential implications for placental transcytosis.
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| Walton JR, Frey HA, Vandre DD, Kwiek JJ, Ishikawa T, Takizawa T, Robinson JM, Ackerman WE 4th.
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| Histochem Cell Biol 139(3):487-500. doi: 10.1007/s00418-012-1040-2. Epub 2012 Oct 14.
2013
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4 | FLOT1, FLOT2
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| Flotillin-2 is associated with breast cancer progression and poor survival outcomes.
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| Wang X, Yang Q, Guo L, Li XH, Zhao XH, Song LB, Lin HX.
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| J Transl Med 11:190. doi: 10.1186/1479-5876-11-190.
2013
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5 | FLOT2
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| Expression profile of flotillin-2 and its pathophysiological role after spinal cord injury.
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| Santiago JM, Torrado AI, Arocho LC, Rosas OR, Rodríguez AE, Toro FK, Salgado IK, Torres YA, Silva WI, Miranda JD.
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| J Mol Neurosci 49(2):347-59. doi: 10.1007/s12031-012-9873-7. Epub 2012 Aug 10.
2013
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6 | FLOT1, FLOT2
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| Reggies/flotillins regulate E-cadherin-mediated cell contact formation by affecting EGFR trafficking.
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| Solis GP, Schrock Y, Hülsbusch N, Wiechers M, Plattner H, Stuermer CA.
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| Mol Biol Cell 23(10):1812-25. doi: 10.1091/mbc.E11-12-1006. Epub 2012 Mar 21.
2012
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7 | FLOT2, KIF9
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| The kinesin KIF9 and reggie/flotillin proteins regulate matrix degradation by macrophage podosomes.
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| Cornfine S, Himmel M, Kopp P, El Azzouzi K, Wiesner C, Krüger M, Rudel T, Linder S.
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| Mol Biol Cell 22(2):202-15. Epub 2010 Nov 30.
2011
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8 | FLOT1, FLOT2, NPC1L1
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| Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.
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| Ge L, Qi W, Wang LJ, Miao HH, Qu YX, Li BL, Song BL.
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| Proc Natl Acad Sci U S A 108(2):551-6. doi: 10.1073/pnas.1014434108. Epub 2010 Dec 27.
2011
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9 | FLOT1, FLOT2
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| Cellular roles of the prion protein in association with reggie/flotillin microdomains.
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| Solis GP, Malaga-Trillo E, Plattner H, Stuermer CA.
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| Front Biosci (Landmark Ed) 15:1075-85. Review.
2010
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10 | FLOT1, FLOT2
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| Flotillin-1 stabilizes caveolin-1 in intestinal epithelial cells.
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| Vassilieva EV, Ivanov AI, Nusrat A.
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| Biochem Biophys Res Commun 379(2):460-5. Epub 2008 Dec 31.
2009
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11 | FLOT1, FLOT2
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| Endocytosis of flotillin-1 and flotillin-2 is regulated by Fyn kinase.
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| Riento K, Frick M, Schafer I, Nichols BJ.
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| J Cell Sci 122(Pt 7):912-8. Epub 2009 Mar 3.
2009
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12 | FLOT2
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| Identification of flotillin-2, a major protein on lipid rafts, as a novel target of p53 family members.
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| Sasaki Y, Oshima Y, Koyama R, Maruyama R, Akashi H, Mita H, Toyota M, Shinomura Y, Imai K, Tokino T.
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| Mol Cancer Res 6(3):395-406. Epub 2008 Feb 22.
2008
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13 | FLOT1, FLOT2
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| Trafficking of the microdomain scaffolding protein reggie-1/flotillin-2.
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| Langhorst MF, Reuter A, Jaeger FA, Wippich FM, Luxenhofer G, Plattner H, Stuermer CA.
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| Eur J Cell Biol 87(4):211-26. Epub 2008 Jan 30.
2008
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14 | FLOT1, FLOT2
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| Coassembly of flotillins induces formation of membrane microdomains, membrane curvature, and vesicle budding.
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| Frick M, Bright NA, Riento K, Bray A, Merrified C, Nichols BJ.
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| Curr Biol 17(13):1151-6.
2007
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15 | FLOT2
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| Linking membrane microdomains to the cytoskeleton: regulation of the lateral mobility of reggie-1/flotillin-2 by interaction with actin.
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| Langhorst MF, Solis GP, Hannbeck S, Plattner H, Stuermer CA.
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| FEBS Lett 581(24):4697-703. Epub 2007 Sep 6.
2007
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16 | FLOT1, FLOT2
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| Reggie-1 and reggie-2 localize in non-caveolar rafts in epithelial cells: cellular localization is not dependent on the expression of caveolin proteins.
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| Fernow I, Icking A, Tikkanen R.
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| Eur J Cell Biol 86(6):345-52. Epub 2007 May 7.
2007
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17 | FLOT2
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| Up-regulation of Flotillin-2 is associated with melanoma progression and modulates expression of the thrombin receptor protease activated receptor 1.
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| Hazarika P, McCarty MF, Prieto VG, George S, Babu D, Koul D, Bar-Eli M, Duvic M.
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| Cancer Res 64(20):7361-9.
2004
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18 | CBL, FLOT1, FLOT2, LPCN, SORBS1
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| CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
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| Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, Bickel PE, Pessin JE, Saltiel AR.
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| Nature 407(6801):202-7. 2000
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19 | FLOT1, FLOT2
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| Flotillin 2 is distinct from epidermal surface antigen (ESA) and is associated with filopodia formation.
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| Hazarika P, Dham N, Patel P, Cho M, Weidner D, Goldsmith L, Duvic M.
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| J Cell Biochem 75(1):147-59. 1999
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20 | FLOT2
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| Flotillin and epidermal surface antigen define a new family of caveolae-associated integral membrane proteins.
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| Bickel PE, et al.
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| J Biol Chem 272 : 13793-13802. 1997
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21 | FLOT2
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| Epidermal surface antigen (MS17S1) is highly conserved between mouse andhuman.
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| Cho YJ, et al.
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| Genomics 27 : 251-258. 1995
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22 | FLOT2
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| The gene for a novel epidermal antigen maps near the neurofibromatosis 1 gene.
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| Kayes LM, et al.
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| Genomics 14 : 369-376. 1992
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23 | FLOT2
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| The human gene for an epidermal surface antigen (M17S1) is located at 17q11-q12.
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| Schroeder WT, et al.
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| Genomics 11 : 481-482. 1991
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24 | FLOT2
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| An epidermal surface antigen gene maps near the neurofibromatosis type 1gene.
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| Kayes L, et al.
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| Am J Hum Genet 49S : 418. 1991
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