Citations for
1FLI1, MYH9, TRPV4
TRPV4 mediates the Ca2+ influx required for the interaction between flightless-1 and non-muscle myosin, and collagen remodeling.
Arora PD, Di Gregorio M, He P, McCulloch CA.
J Cell Sci 130(13):2196-2208. doi: 10.1242/jcs.201665. Epub 2017 May 19. 2017
2FLI1, GATA1, GFI1B, RUNX1
Inherited platelet dysfunction and hematopoietic transcription factor mutations.
Songdej N, Rao AK.
Platelets latelets. 2016 Jul 27:1-7. [Epub ahead of print] 2016
3FLI1
Oncogenic fusion protein EWS-FLI1 is a network hub that regulates alternative splicing.
Selvanathan SP, Graham GT, Erkizan HV, Dirksen U, Natarajan TG, Dakic A, Yu S, Liu X, Paulsen MT, Ljungman ME, Wu CH, Lawlor ER, ▄ren A, Toretsky JA.
Proc Natl Acad Sci U S A 112(11):E1307-16. doi: 10.1073/pnas.1500536112. Epub 2015 Mar 3. 2015
4CCL2, FLI1
Fli-1 controls transcription from the MCP-1 gene promoter, which may provide a novel mechanism for chemokine and cytokine activation.
Lennard Richard ML, Nowling TK, Brandon D, Watson DK, Zhang XK.
Mol Immunol 63(2):566-73. doi: 10.1016/j.molimm.2014.07.013. Epub 2014 Aug 6. 2015
5CCL5, ETS1, FLI1
The Fli-1 transcription factor regulates the expression of CCL5/RANTES.
Lennard Richard ML, Sato S, Suzuki E, Williams S, Nowling TK, Zhang XK.
J Immunol 193(6):2661-8. doi: 10.4049/jimmunol.1302779. Epub 2014 Aug 6. 2014
6FLI1
Oncogenic Fli-1 is a potential prognostic marker for the progression of epithelial ovarian cancer.
Song W, Hu L, Li W, Wang G, Li Y, Yan L, Li A, Cui J.
BMC Cancer 14:424. doi: 10.1186/1471-2407-14-424. 2014
7ETS1, FLI1
Deregulation of ETS1 and FLI1 contributes to the pathogenesis of diffuse large B-cell lymphoma.
Bonetti P, Testoni M, Scandurra M, Ponzoni M, Piva R, Mensah AA, Rinaldi A, Kwee I, Tibiletti MG, Iqbal J, Greiner TC, Chan WC, Gaidano G, Piris MA, Cavalli F, Zucca E, Inghirami G, Bertoni F.
Blood 122(13):2233-41. doi: 10.1182/blood-2013-01-475772. Epub 2013 Aug 7. Erratum in: Blood. 2014 May 8;123(19):3056. 2013
8FLI1
Fli-1 overexpression in hematopoietic progenitors deregulates T cell development and induces pre-T cell lymphoblastic leukaemia/lymphoma.
Smeets MF, Chan AC, Dagger S, Bradley CK, Wei A, Izon DJ.
PLoS One 8(5):e62346. doi: 10.1371/journal.pone.0062346. Print 2013. 2013
9FLI1
The transcription factor Fli-1 regulates monocyte, macrophage and dendritic cell development in mice.
Suzuki E, Williams S, Sato S, Gilkeson G, Watson DK, Zhang XK.
Immunology 139(3):318-27. doi: 10.1111/imm.12070. 2013
10FLI1, KLF1
Transcription factors Fli1 and EKLF in the differentiation of megakaryocytic and erythroid progenitor in 5q- syndrome and in Diamond-Blackfan anemia.
Neuwirtova R, Fuchs O, Holicka M, Vostry M, Kostecka A, Hajkova H, Jonasova A, Cermak J, Cmejla R, Pospisilova D, Belickova M, Siskova M, Hochova I, Vondrakova J, Sponerova D, Kadlckova E, Novakova L, Brezinova J, Michalova K.
Ann Hematol 92(1):11-8. doi: 10.1007/s00277-012-1568-1. Epub 2012 Sep 11. 2013
11DEL11QD, FLI1
SNP array and phenotype correlation shows that FLI1 deletion per se is not responsible for thrombocytopenia development in Jacobsen syndrome.
Trkova M, Becvarova V, Hynek M, Hnykova L, Hlavova E, Kreckova G, Kulovany E, Cutka D, Zatloukalova J, Markova K, Sukova M, Horacek J, Stejskal D.
Am J Med Genet A 158A(10):2545-50. doi: 10.1002/ajmg.a.35537. Epub 2012 Aug 7. 2012
12FLI1, SLC45A3
FLI1 is a novel ETS transcription factor involved in gene fusions in prostate cancer.
Paulo P, Barros-Silva JD, Ribeiro FR, Ramalho-Carvalho J, Jerˇnimo C, Henrique R, Lind GE, Skotheim RI, Lothe RA, Teixeira MR.
Genes Chromosomes Cancer 51(3):240-9. doi: 10.1002/gcc.20948. Epub 2011 Nov 12. 2012
13ESR1, FLI1
Fli1 is a negative regulator of estrogen receptor α in dermal fibroblasts.
Hattori T, Stawski L, Nakerakanti SS, Trojanowska M.
J Invest Dermatol 131(7):1469-76. doi: 10.1038/jid.2011.63. Epub 2011 Mar 31. 2011
14ELF1, ETS1, ETS2, FLI1
The mouse and human Fli1 genes are similarly regulated by Ets factors in T cells.
Svenson JL, Chike-Harris K, Amria MY, Nowling TK.
Genes Immun 11(2):161-72. Epub 2009 Oct 15.PMID: 19829305 2010
15EWSR1, FLI1, FOXO1
FOXO1 is a direct target of EWS-Fli1 oncogenic fusion protein in Ewing's sarcoma cells.
Yang L, Hu HM, Zielinska-Kwiatkowska A, Chansky HA.
Biochem Biophys Res Commun 402(1):129-34. doi: 10.1016/j.bbrc.2010.09.129. Epub 2010 Oct 8. 2010
16EWSR1, FLI1, GLI1
GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein.
Beauchamp E, Bulut G, Abaan O, Chen K, Merchant A, Matsui W, Endo Y, Rubin JS, Toretsky J, Uren A.
J Biol Chem 284(14):9074-82. Epub 2009 Feb 3. 2009
17EWSR1, FLI1
A small molecule blocking oncogenic protein EWS-FLI1 interaction with RNA helicase A inhibits growth of Ewing's sarcoma.
Erkizan HV, Kong Y, Merchant M, Schlottmann S, Barber-Rotenberg JS, Yuan L, Abaan OD, Chou TH, Dakshanamurthy S, Brown ML, Uren A, Toretsky JA.
Nat Med 15(7):750-6. Epub 2009 Jul 5. 2009
18DEL11QD, FLI1, TCDM
Clinical and molecular-cytogenetic evaluation of a family with partial Jacobsen syndrome without thrombocytopenia caused by an approximately 5 Mb deletion del(11)(q24.3).
Bernaciak J, Szcza│uba K, Derwi˝ska K, Wiťniowiecka-Kowalnik B, Bocian E, Sasiadek MM, Makowska I, Stankiewicz P, Smigiel R.
Am J Med Genet A 146A(19):2449-54. 2008
19FLI1
Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus.
Miyagawa H, Yamai M, Sakaguchi D, Kiyohara C, Tsukamoto H, Kimoto Y, Nakamura T, Lee JH, Tsai CY, Chiang BL, Shimoda T, Harada M, Tahira T, Hayashi K, Horiuchi T.
Rheumatology (Oxford) 47(2):158-64. Epub 2008 Jan 3.PMID: 18174230 2008
20FLI1
Fli-1 expression in malignant melanoma.
Torlakovic EE, Slipicevic A, Fl°renes VA, Chibbar R, DeCoteau JF, Bilalovic N.
Histol Histopathol 23(11):1309-14.PMID: 18785112 2008
21ELF1, FLI1
Ets factors and a newly identified polymorphism regulate Fli1 promoter activity in lymphocytes.
Nowling TK, Fulton JD, Chike-Harris K, Gilkeson GS.
Mol Immunol 45(1):1-12. Epub 2007 Jul 2.PMID: 17606295 2008
22FLI1
Functional roles of Fli-1, a member of the Ets family of transcription factors, in human breast malignancy.
Sakurai T, Kondoh N, Arai M, Hamada J, Yamada T, Kihara-Negishi F, Izawa T, Ohno H, Yamamoto M, Oikawa T.
Cancer Sci 98(11):1775-84.PMID: 17727680 2007
23FLI1, GATA2
Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development.
Pimanda JE, Ottersbach K, Knezevic K, Kinston S, Chan WY, Wilson NK, Landry JR, Wood AD, Kolb-Kokocinski A, Green AR, Tannahill D, Lacaud G, Kouskoff V, G÷ttgens B.
Proc Natl Acad Sci U S A 104(45):17692-7. Epub 2007 Oct 25.PMID: 17962413 2007
24FLI1, NFRKB, SNX19
Amplified, lost, and fused genes in 11q23-25 amplicon in acute myeloid leukemia, an array-CGH study.
Tyybakinoja A, Saarinen-Pihkala U, Elonen E, Knuutila S.
Genes Chromosomes Cancer 45(3):257-64. 2006
25FLI1
Association between enhanced type I collagen expression and epigenetic repression of the FLI1 gene in scleroderma fibroblasts.
Wang Y, Fan PS, Kahaleh B.
Arthritis Rheum 54(7):2271-9. 2006
26GATA1, FLI1, ITGA2B, GP9
Ets-dependent regulation of target gene expression during megakaryopoiesis.
Jackers P, Szalai G, Moussa O, Watson DK.
J Biol Chem 279(50):52183-90. Epub 2004 Oct 5. Erratum in: J Biol Chem. 2005 Jul 1;280(26):25304. 2004
27FLI1, TCDM, DEL11QD
FLI1 monoallelic expression combined with its hemizygous loss underlies Paris-Trousseau/Jacobsen thrombopenia.
Raslova H, Komura E, Le Couedic JP, Larbret F, Debili N, Feunteun J, Danos O, Albagli O, Vainchenker W, Favier R.
J Clin Invest 114(1):77-84. 2004
28EWSR1, FLI1
Arrangement of chromosome 11 and 22 territories, EWSR1 and FLI1 genes, and other genetic elements of these chromosomes in human lymphocytes and Ewing sarcoma cells
Taslerova R, Kozubek S, Lukasova E, Jirsova P, Bartova E, Kozubek M.
Hum Genet 112(2):143-55. 2003
29FLI1, TBX1, GP6, SPI1
Cloning and analysis of the thrombopoietin-induced megakaryocyte-specific glycoprotein VI promoter and its regulation by GATA-1, Fli-1, and Sp1.
Holmes ML, Bartle N, Eisbacher M, Chong BH.
J Biol Chem 277(50):48333-41. 2002
30ID2, EWSR1, FLI1, ERG
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Nishimori H, Sasaki Y, Yoshida K, Irifune H, Zembutsu H, Tanaka T, Aoyama T, Hosaka T, Kawaguchi S, Wada T, Hata J, Toguchida J, Nakamura Y, Tokino T.
Oncogene 21(54):8302-9. 2002
31FLI1
Hemorrhage, impaired hematopoiesis, and lethality in mouse embryos carrying a targeted disruption of the Fli1 transcription factor.
Spyropoulos DD, Pharr PN, Lavenburg KR, Jackers P, Papas TS, Ogawa M, Watson DK.
Mol Cell Biol 20(15):5643-52. 2000
32FLI1
Translocation of chromosomes 11 and 22 in choroidal metastatic Ewing sarcoma detected by fluorescent in situ hybridization.
Chan CC, et al.
Am J Ophthalmol 127(2):226-8. 1999
33FLI1
Characterization of a novel Ras-binding protein Ce-FLI-1 comprising leucine-rich repeats and gelsolin-like domains.
Goshima M, et al.
Biochem Biophys Res Commun 257(1):111-6. 1999
34TGFBR2, EWSR1, FLI1
Repression of the gene encoding the TGF-beta type II receptor is a major target of the EWS-FLI1 oncoprotein.
Hahm KB, et al.
Nat Genet 23(2):222-7 1999
35EWSR1, FLI1
Biphenotypic sarcomas with myogenic and neural differentiation express the Ewing's sarcoma EWS/FLI1 fusion gene.
Sorensen PH, et al.
Cancer Res 55 : 1385-1392. 1995
36FLI1
High-resolution physical mapping of a 250-kb region of human chromosome 11q24 by genomic sequence sampling (GSS).
Selleri L, et al.
Genomics 26 : 489-501. 1995
37ERG, EWSR1, EWSR1, FLI1
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG.
Sorensen PHB, et al.
Nat Genet 6 : 146-151. 1994
38FLI1
Cloning of the entire FLI1 gene, disrupted by the Ewing's Sarcoma translocation breakpoint on 11q24, in a yeast artificial chromosome.
Selleri L, et al.
Cytogenet Cell Genet 67 : 129-136. 1994
39FLI1
Yeast artificial chromosome cloning of 3.2 megabases within chromosomal band 11q24 closely linking c-ets 1 and Fli-1 and encompassing the Ewing sarcoma breakpoint.
Selleri L, et al.
Genomics 22 : 137-147. 1994
40EWSR1, FLI1
DNA-binding and transcriptional activation properties of the EWS-FLI-1 fusion protein resulting from the t(11;22) translocation in Ewing sarcoma.
Bailly RA, et al.
Mol Cell Biol 14 : 3230-3241. 1994
41EWSR1, FLI1
EWS/FLi-1 chimeric protein is a transcriptional activator.
Ohno T, et al.
Cancer Res 53 : 5859-5863. 1993
42FLI1
Human FLI-1 localizes to chromosome 11q24 and has an aberrant transcript in neuroepithelioma.
Hromas R, et al.
Biochim Biophys Acta 1172 : 155-158. 1993
43EWSR1, FLI1
Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.
May WA, et al.
Proc Natl Acad Sci U S A 90 : 5752-5756. 1993
44EWSR1, EWSR1, FLI1
Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours.
Delattre O, et al.
Nature 359 : 162-166. 1992
45EWSR1, FLI1
Cloning and characterization of the Ewing's sarcoma and peripheral neuroepithelioma t(11;22) translocation breakpoints.
Zucman J, et al.
Genes Chromosomes Cancer 5 : 271-277. 1992
46FLI1
The human homolog of the mouse common viral integration region, FLI1, maps to 11q23-q24.
Baud V, et al.
Genomics 11 : 223-224. 1991
47EWSR1, FLI1, CBL, LIF
Molecular localization of the t(11;22)(q24;q12) translocation of Ewing sarcoma by chromosomal in situ suppression hybridization.
Selleri L, et al.
Proc Natl Acad Sci U S A 88 : 887-891. 1991
48EWSR1, FLI1
Chromosomes in Ewing's sarcoma. I.An evaluation of 85 cases and remarkable consistency of t(11;22)(q24;q12).
Turc-Carel C, et al.
Cancer Genet Cytogenet 32 : 229-238. 1988
49EWSR1, FLI1
Chromosome study of Ewing's sarcoma (ES) cell lines. Consistency of a reciprocal translocation t(11;22)(q24;q12).
Turc-Carel C, et al.
Cancer Genet Cytogenet 12 : 1-19. 1984
50EWSR1, FLI1
Chromosome translocation in peripheral neuroepithelioma.
Whang-Peng J, et al.
N Engl J Med 311 : 584-585. 1984
51EWSR1, FLI1
Chromosomal translocations in Ewing's sarcoma.
Turc-Carel C, et al.
N Engl J Med 309 : 497-498. 1983