| 1 | FHL1, FHL2, FHL3
|
| Four-and-a-half LIM domain proteins inhibit transactivation by hypoxia-inducible factor 1.
|
| Hubbi ME, Gilkes DM, Baek JH, Semenza GL.
|
| J Biol Chem 287(9):6139-49. Epub 2012 Jan 4.
2012
|
| 2 | FHL2
|
| Characterization of human FHL2 transcript variants and gene expression regulation in hepatocellular carcinoma.
|
| Ng CF, Zhou WJ, Ng PK, Li MS, Ng YK, Lai PB, Tsui SK.
|
| Gene 481(1):41-7. Epub 2011 Apr 22.
2011
|
| 3 | FHL2, NR4A1
|
| FHL2 protein is a novel co-repressor of nuclear receptor Nur77.
|
| Kurakula K, van der Wal E, Geerts D, van Tiel CM, de Vries CJ.
|
| J Biol Chem 286(52):44336-43. doi: 10.1074/jbc.M111.308999. Epub 2011 Nov 2.
2011
|
| 4 | CCL19, FHL2
|
| Four-and-a-half LIM domain protein 2 is a novel regulator of sphingosine 1-phosphate receptor 1 in CCL19-induced dendritic cell migration.
|
| König K, Diehl L, Rommerscheidt-Fuss U, Golletz C, Quast T, Kahl P, Kolanus W, Knolle P, Buettner R, Heukamp LC.
|
| J Immunol 185(3):1466-75. Epub 2010 Jun 30.
2010
|
| 5 | FHL2, FOXK1
|
| Fhl2 interacts with Foxk1 and corepresses Foxo4 activity in myogenic progenitors.
|
| Shi X, Bowlin KM, Garry DJ.
|
| Stem Cells 28(3):462-9.
2010
|
| 6 | FHL2, ID2
|
| FHL2 interacts with and acts as a functional repressor of Id2 in human neuroblastoma cells.
|
| Han W, Wu Z, Zhao Y, Meng Y, Si Y, Yang J, Fu X, Yu L.
|
| Nucleic Acids Res 37(12):3996-4009. Epub 2009 May 5.
2009
|
| 7 | FHL2
|
| FHL-2 suppresses VEGF-induced phosphatidylinositol 3-kinase/Akt activation via interaction with sphingosine kinase-1.
|
| Hayashi H, Nakagami H, Takami Y, Koriyama H, Mori M, Tamai K, Sun J, Nagao K, Morishita R, Kaneda Y.
|
| Arterioscler Thromb Vasc Biol 29(6):909-14. Epub 2009 Mar 26.
2009
|
| 8 | FHL1, FHL2, FHL3
|
| Human four-and-a-half LIM family members suppress tumor cell growth through a TGF-beta-like signaling pathway.
|
| Ding L, Wang Z, Yan J, Yang X, Liu A, Qiu W, Zhu J, Han J, Zhang H, Lin J, Cheng L, Qin X, Niu C, Yuan B, Wang X, Zhu C, Zhou Y, Li J, Song H, Huang C, Ye Q.
|
| J Clin Invest 119(2):349-61. doi: 10.1172/JCI35930. Epub 2009 Jan 12.
2009
|
| 9 | FHL2, CCND1
|
| The LIM-only protein FHL2 regulates cyclin D1 expression and cell proliferation.
|
| Labalette C, Nou‘t Y, Sobczak-Thepot J, Armengol C, Levillayer F, Gendron MC, Renard CA, Regnault B, Chen J, Buendia MA, Wei Y.
|
| J Biol Chem 283(22):15201-8. Epub 2008 Mar 31. 2008
|
| 10 | FHL2
|
| Deficiency in the LIM-only protein FHL2 impairs assembly of extracellular matrix proteins.
|
| Park J, Will C, Martin B, Gullotti L, Friedrichs N, Buettner R, Schneider H, Ludwig S, Wixler V.
|
| FASEB J 22(7):2508-20. Epub 2008 Mar 20.
2008
|
| 11 | FHL2, KCNH2
|
| The four and a half LIM domain protein 2 interacts with and regulates the HERG channel.
|
| Lin J, Lin S, Yu X, Choy PC, Shen X, Deng C, Kuang S, Wu J.
|
| FEBS J 275(18):4531-9. Epub 2008 Aug 1.
2008
|
| 12 | TRIM54, FLNC, FHL2
|
| Loss of muscle-specific RING-finger 3 predisposes the heart to cardiac rupture after myocardial infarction.
|
| Fielitz J, van Rooij E, Spencer JA, Shelton JM, Latif S, van der Nagel R, Bezprozvannaya S, de Windt L, Richardson JA, Bassel-Duby R, Olson EN.
|
| Proc Natl Acad Sci U S A 104(11):4377-82. Epub 2007 Mar 2. 2007
|
| 13 | FHL2, CMD1H
|
| Structural analysis of four and half LIM protein-2 in dilated cardiomyopathy.
|
| Arimura T, Hayashi T, Matsumoto Y, Shibata H, Hiroi S, Nakamura T, Inagaki N, Hinohara K, Takahashi M, Manatsu SI, Sasaoka T, Izumi T, Bonne G, Schwartz K, Kimura A.
|
| Biochem Biophys Res Commun 357(1):162-7. Epub 2007 Mar 30. 2007
|
| 14 | E4F1, FHL2
|
| The LIM-only protein FHL2 is a negative regulator of E4F1.
|
| Paul C, Lacroix M, Iankova I, Julien E, SchŠfer BW, Labalette C, Wei Y, Le Cam A, Le Cam L, Sardet C.
|
| Oncogene 25(40):5475-84. Epub 2006 May 1. 2006
|
| 15 | FHL2,TNFRSF11A,TRAF6
|
| FHL2 inhibits the activated osteoclast in a TRAF6-dependent manner.
|
| Bai S, Kitaura H, Zhao H, Chen J, Muller JM, Schule R, Darnay B, Novack DV, Ross FP, Teitelbaum SL.
|
| J Clin Invest 115(10):2742-51. Epub 2005 Sep 22. 2005
|
| 16 | FHL2, MAPK1
|
| Extracellular signal-regulated kinase 2 interacts with and is negatively regulated by the LIM-only protein FHL2 in cardiomyocytes.
|
| Purcell NH, Darwis D, Bueno OF, Muller JM, Schule R, Molkentin JD.
|
| Mol Cell Biol 24(3):1081-95. 2004
|
| 17 | FHL2, PIAS1, UBE2I
|
| FHL2, UBC9, and PIAS1 are novel estrogen receptor alpha-interacting proteins.
|
| Kobayashi S, Shibata H, Yokota K, Suda N, Murai A, Kurihara I, Saito I, Saruta T.
|
| Endocr Res 30(4):617-21. 2004
|
| 18 | FHL2, IGFBP5
|
| Insulin-like growth factor-binding protein 5 (IGFBP-5) interacts with a four and a half LIM protein 2 (FHL2).
|
| Amaar YG, Thompson GR, Linkhart TA, Chen ST, Baylink DJ, Mohan S.
|
| J Biol Chem 277(14):12053-60. 2002
|
| 19 | FHL2, ZBTB16
|
| The LIM-only protein DRAL/FHL2 interacts with and is a corepressor for the promyelocytic leukemia zinc finger protein.
|
| McLoughlin P, Ehler E, Carlile G, Licht JD, Schafer BW.
|
| J Biol Chem 277(40):37045-53. 2002
|
| 20 | FHL2, ZNF638
|
| Interaction of the heart-specific LIM domain protein, FHL2, with DNA-binding nuclear protein, hNP220.
|
| Ng EK, Chan KK, Wong CH, Tsui SK, Ngai SM, Lee SM, Kotaka M, Lee CY, Waye MM, Fung KP.
|
| J Cell Biochem 84(3):556-66. 2002
|
| 21 | FHL2, TTN
|
| Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2.
|
| Lange S, Auerbach D, McLoughlin P, Perriard E, Schafer BW, Perriard JC, Ehler E.
|
| J Cell Sci 115(Pt 24):4925-36. 2002
|
| 22 | FHL2
|
| FHL2, a novel tissue-specific coactivator of the androgen receptor.
|
| Muller JM, Isele U, Metzger E, Rempel A, Moser M, Pscherer A, Breyer T, Holubarsch C, Buettner R, Schule R.
|
| EMBO J 19(3):359-369 2000
|
| 23 | AD4, FHL2, PSEN2
|
| Alzheimer's disease-associated presenilin 2 interacts with DRAL, an LIM-domain protein
|
| Tanahashi H, Tabira T.
|
| Hum Mol Genet 9(15):2281-9. 2000
|
| 24 | FHL2
|
| The LIM-only protein DRAL/FHL2 binds to the cytoplasmic domain of several alpha and beta integrin chains and is recruited to adhesion complexes.
|
| Wixler V, Geerts D, Laplantine E, Westhoff D, Smyth N, Aumailley M, Sonnenberg A, Paulsson M.
|
| J Biol Chem 275(43):33669-78. 2000
|
| 25 | FHL2
|
| Molecular cloning and characterization of FHL2, a novel LIM domain protein preferentially expressed in human heart.
|
| Chan KK, et al.
|
| Gene 210 : 345-350. 1998
|
| 26 | FHL2
|
| Subtractive cloning and characterization of DRAL, a novel LIM-domain protein down-regulated in rhabdomyosarcoma.
|
| Genini M, et al.
|
| DNA Cell Biol 16 : 433-442. 1997
|
| 27 | FHL2, FHL3
|
| Slim defines a novel family of LIM-proteins expressed in skeletal muscle.
|
| Morgan MJ, Madgwick AJ.
|
| Biochem Biophys Res Commun 225(2):632-8. 1996
|