| 1 | FGF10, FGFR2, TBX4
|
| Complex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway.
|
| Karolak JA, Vincent M, Deutsch G, Gambin T, Cogné B, Pichon O, Vetrini F, Mefford HC, Dines JN, Golden-Grant K, Dipple K, Freed AS, Leppig KA, Dishop M, Mowat D, Bennetts B, Gifford AJ, Weber MA, Lee AF, Boerkoel CF, Bartell TM, Ward-Melver C, Besnard T, Petit F, Bache I, Tümer Z, Denis-Musquer M, Joubert M, Martinovic J, Bénéteau C, Molin A, Carles D, André G, Bieth E, Chassaing N, Devisme L, Chalabreysse L, Pasquier L, Secq V, Don M, Orsaria M, Missirian C, Mortreux J, Sanlaville D, Pons L, Küry S, Bézieau S, Liet JM, Joram N, Bihouée T, Scott DA, Brown CW, Scaglia F, Tsai AC, Grange DK, Phillips JA 3rd, Pfotenhauer JP, Jhangiani SN, Gonzaga-Jauregui CG, Chung WK, Schauer GM, Lipson MH, Mercer CL, van Haeringen A, Liu Q, Popek E, Coban Akdemir ZH, Lupski JR, Szafranski P, Isidor B, Le Caignec C, Stankiewicz P.
|
| Am J Hum Genet 104(2):213-228. doi: 10.1016/j.ajhg.2018.12.010. Epub 2019 Jan 10.
2019
|
| 2 | FGFR2
|
| A requirement for Fgfr2 in middle ear development.
|
| Rigueur D, Roberts RR, Bobzin L, Merrill AE.
|
| Genesis 57(1):e23252. doi: 10.1002/dvg.23252. Epub 2018 Oct 4.
2019
|
| 3 | FGFR2, KLK2
|
| Characterization of a KLK2-FGFR2 fusion gene in two cases of metastatic prostate cancer.
|
| Krook MA, Barker H, Chen HZ, Reeser JW, Wing MR, Martin D, Smith AM, Dao T, Bonneville R, Samorodnitsky E, Miya J, Freud AG, Monk JP, Clinton SK, Roychowdhury S.
|
| Prostate Cancer Prostatic Dis 22(4):624-632. doi: 10.1038/s41391-019-0145-2. Epub 2019 May 1.
2019
|
| 4 | FGFR2
|
| Midface and upper airway dysgenesis in FGFR2-related craniosynostosis involves multiple tissue-specific and cell cycle effects.
|
| Holmes G, O'Rourke C, Motch Perrine SM, Lu N, van Bakel H, Richtsmeier JT, Jabs EW.
|
| Development 145(19). pii: dev166488. doi: 10.1242/dev.166488.
2018
|
| 5 | CRS5A, FGFR2
|
| An inherited FGFR2 mutation increased osteogenesis gene expression and result in Crouzon syndrome.
|
| Fan J, Li Y, Jia R, Fan X.
|
| BMC Med Genet 19(1):91. doi: 10.1186/s12881-018-0607-8.
2018
|
| 6 | FGFR2
|
| Inactivation of Fgfr2 gene in mouse secondary palate mesenchymal cells leads to cleft palate.
|
| Jin JZ, Lei Z, Lan ZJ, Mukhopadhyay P, Ding J.
|
| Reprod Toxicol 77:137-142. doi: 10.1016/j.reprotox.2018.03.004. Epub 2018 Mar 8.
2018
|
| 7 | FGFR2
|
| Expression of the FGFR2c mesenchymal splicing variant in human keratinocytes inhibits differentiation and promotes invasion.
|
| Ranieri D, Rosato B, Nanni M, Belleudi F, Torrisi MR.
|
| Mol Carcinog 57(2):272-283. doi: 10.1002/mc.22754. Epub 2017 Nov 14.
2018
|
| 8 | FGFR2
|
| Interplay between FGFR2b-induced autophagy and phagocytosis: role of PLCγ-mediated signalling.
|
| Nanni M, Ranieri D, Raffa S, Torrisi MR, Belleudi F.
|
| J Cell Mol Med 22(1):668-683. doi: 10.1111/jcmm.13352. Epub 2017 Oct 10.
2018
|
| 9 | FGFR2
|
| Role of fibroblast growth factor receptor-2 splicing in normal and cancer cells.
|
| Ishiwata T.
|
| Front Biosci (Landmark Ed) 23:626-639. Review.
2018
|
| 10 | DDX6, ERBB2, FGFR2
|
| DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells.
|
| Tajirika T, Tokumaru Y, Taniguchi K, Sugito N, Matsuhashi N, Futamura M, Yanagihara K, Akao Y, Yoshida K.
|
| Int J Mol Sci 19(7). pii: E2005. doi: 10.3390/ijms19072005.
2018
|
| 11 | FGFR2, NEGR1
|
| NEGR1 and FGFR2 cooperatively regulate cortical development and core behaviours related to autism disorders in mice.
|
| Szczurkowska J, Pischedda F, Pinto B, Managň F, Haas CA, Summa M, Bertorelli R, Papaleo F, Schäfer MK, Piccoli G, Cancedda L.
|
| Brain Sep 1;141(9):2772-2794. doi: 10.1093/brain/awy190 2018
|
| 12 | FGFR2
|
| Fibroblast Growth Factor Receptor 2 (FGFR2) Mutation Related Syndromic Craniosynostosis.
|
| Azoury SC, Reddy S, Shukla V, Deng CX.
|
| Int J Biol Sci 13(12):1479-1488. doi: 10.7150/ijbs.22373. eCollection 2017. Review.
2017
|
| 13 | FGFR2
|
| Testis Determination Requires a Specific FGFR2 Isoform to Repress FOXL2.
|
| Bagheri-Fam S, Bird AD, Zhao L, Ryan JM, Yong M, Wilhelm D, Koopman P, Eswarakumar VP, Harley VR.
|
| Endocrinology 158(11):3832-3843. doi: 10.1210/en.2017-00674.
2017
|
| 14 | BBDS, FGFR2
|
| FGFR2 mutations in bent bone dysplasia syndrome activate nucleolar stress and perturb cell fate determination.
|
| Neben CL, Tuzon CT, Mao X, Lay FD, Merrill AE.
|
| Hum Mol Genet 26(17):3253-3270. doi: 10.1093/hmg/ddx209.
2017
|
| 15 | FGFR2
|
| FGFR2 is required for airway basal cell self-renewal and terminal differentiation.
|
| Balasooriya GI, Goschorska M, Piddini E, Rawlins EL.
|
| Development 144(9):1600-1606. doi: 10.1242/dev.135681. Epub 2017 Mar 27.
2017
|
| 16 | FGFR2, RPS6KA3
|
| Interactions between FGFR2 and RSK2-implications for breast cancer prognosis.
|
| Czaplinska D, Mieczkowski K, Supernat A, Skladanowski AC, Kordek R, Biernat W, Zaczek AJ, Romanska HM, Sadej R.
|
| Tumour Biol 37(10):13721-13731. Epub 2016 Jul 30.
2016
|
| 17 | ADAM10, FGFR2, NEGR1
|
| The IgLON Family Member Negr1 Promotes Neuronal Arborization Acting as Soluble Factor via FGFR2.
|
| Pischedda F, Piccoli G.
|
| Front Mol Neurosci. Jan 13;8:89. doi: 10.3389/fnmol.2015.00089. eCollection 2015 2016
|
| 18 | FGFR1, FGFR2
|
| Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation.
|
| Yu K, Karuppaiah K, Ornitz DM.
|
| Dev Dyn 244(11):1427-38. doi: 10.1002/dvdy.24319. Epub 2015 Aug 24.
2015
|
| 19 | FGFR2
|
| Tissue-specific roles of Fgfr2 in development of the external genitalia.
|
| Gredler ML, Seifert AW, Cohn MJ.
|
| Development 142(12):2203-12. doi: 10.1242/dev.119891.
2015
|
| 20 | FGFR2
|
| Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development.
|
| Okazawa M, Murashima A, Harada M, Nakagata N, Noguchi M, Morimoto M, Kimura T, Ornitz DM, Yamada G.
|
| Dev Biol 400(1):139-47. doi: 10.1016/j.ydbio.2015.01.023. Epub 2015 Feb 9.
2015
|
| 21 | ATE1, DELQ10D, FGFR2, NSMCE4A, WDR11
|
| 10q26.1 Microdeletion: Redefining the critical regions for microcephaly and genital anomalies.
|
| Choucair N, Abou Ghoch J, Fawaz A, Mégarbané A, Chouery E.
|
| Am J Med Genet A 167A(11):2707-13. doi: 10.1002/ajmg.a.37211. Epub 2015 Jun 26.
2015
|
| 22 | FGF7, FGFR2
|
| Decreased expression of KGF/FGF7 and its receptor in pathological hypopigmentation.
|
| Purpura V, Persechino F, Belleudi F, Scrofani C, Raffa S, Persechino S, Torrisi MR.
|
| J Cell Mol Med 18(12):2553-7. doi: 10.1111/jcmm.12411. Epub 2014 Oct 14. No abstract available. 2014
|
| 23 | FGFR2, LDB1, LMO4
|
| The co-factor of LIM domains (CLIM/LDB/NLI) maintains basal mammary epithelial stem cells and promotes breast tumorigenesis.
|
| Salmans ML, Yu Z, Watanabe K, Cam E, Sun P, Smyth P, Dai X, Andersen B.
|
| PLoS Genet 10(7):e1004520. doi: 10.1371/journal.pgen.1004520. eCollection 2014 Jul.
2014
|
| 24 | FGFR2
|
| Inhibition of fibroblast growth factor receptor 2 attenuates proliferation and invasion of pancreatic cancer.
|
| Matsuda Y, Yoshimura H, Suzuki T, Uchida E, Naito Z, Ishiwata T.
|
| Cancer Sci 105(9):1212-9. doi: 10.1111/cas.12470. Epub 2014 Sep 3.
2014
|
| 25 | FGFR2
|
| Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice.
|
| Filant J, DeMayo FJ, Pru JK, Lydon JP, Spencer TE.
|
| Biol Reprod 90(1):7. doi: 10.1095/biolreprod.113.114496. Print 2014 Jan.
2014
|
| 26 | FGFR2
|
| FGFR2 Promotes Breast Tumorigenicity through Maintenance of Breast Tumor-Initiating Cells.
|
| Kim S, Dubrovska A, Salamone RJ, Walker JR, Grandinetti KB, Bonamy GM, Orth AP, Elliott J, Porta DG, Garcia-Echeverria C, Reddy VA.
|
| PLoS One 8(1):e51671. doi: 10.1371/journal.pone.0051671. Epub 2013 Jan 2.
2013
|
| 27 | FGFR2, GRB2, PTPN11
|
| Grb2 controls phosphorylation of FGFR2 by inhibiting receptor kinase and Shp2 phosphatase activity.
|
| Ahmed Z, Lin CC, Suen KM, Melo FA, Levitt JA, Suhling K, Ladbury JE.
|
| J Cell Biol 200(4):493-504. doi: 10.1083/jcb.201204106.
2013
|
| 28 | CRS7A, CRS7C, FGFR1, FGFR2
|
| FGFR1 and FGFR2 Mutations in Pfeiffer Syndrome.
|
| Chokdeemboon C, Mahatumarat C, Rojvachiranonda N, Tongkobpetch S, Suphapeetiporn K, Shotelersuk V.
|
| J Craniofac Surg 24(1):150-2. doi: 10.1097/SCS.0b013e3182646454.
2013
|
| 29 | FGF7, FGFR2
|
| FGF7 supports hematopoietic stem and progenitor cells and niche-dependent myeloblastoma cells via autocrine action on bone marrow stromal cells in vitro.
|
| Ishino R, Minami K, Tanaka S, Nagai M, Matsui K, Hasegawa N, Roeder RG, Asano S, Ito M.
|
| Biochem Biophys Res Commun 440(1):125-31. doi: 10.1016/j.bbrc.2013.09.044. Epub 2013 Sep 16.
2013
|
| 30 | FGF17, FGFR2
|
| Fibroblast growth factors in neurodevelopment and psychopathology
|
| Terwisscha van Scheltinga AF, Bakker SC, Kahn RS, Kas MJ.
|
| Neuroscientist. Oct;19(5):479-94. doi: 10.1177/1073858412472399. Epub 2013 Jan 23. 2013
|
| 31 | FGFR2
|
| FGFR2 gene amplification and clinicopathological features in gastric cancer.
|
| Matsumoto K, Arao T, Hamaguchi T, Shimada Y, Kato K, Oda I, Taniguchi H, Koizumi F, Yanagihara K, Sasaki H, Nishio K, Yamada Y.
|
| Br J Cancer 106(4):727-32. doi: 10.1038/bjc.2011.603. Epub 2012 Jan 12.
2012
|
| 32 | FGF9, FGFR2, WNT4
|
| Testis development requires the repression of Wnt4 by Fgf signaling.
|
| Jameson SA, Lin YT, Capel B.
|
| Dev Biol 370(1):24-32. doi: 10.1016/j.ydbio.2012.06.009. Epub 2012 Jun 15.
2012
|
| 33 | FGFR2, NANOG
|
| Fibroblast growth factor receptor 2 homodimerization rapidly reduces transcription of the pluripotency gene Nanog without dissociation of activating transcription factors.
|
| Santostefano KE, Hamazaki T, Pardo CE, Kladde MP, Terada N.
|
| J Biol Chem 287(36):30507-17. doi: 10.1074/jbc.M112.388181. Epub 2012 Jul 11.
2012
|
| 34 | FGFR2
|
| Syndromic craniosynostosis, fibroblast growth factor receptor 2 (FGFR2) mutations, and sacrococcygeal eversion presenting as human tails.
|
| Wilkinson CC, Manchester DK, Keating RF, Ketch LL, Winston KR.
|
| Childs Nerv Syst 28(8):1221-6. doi: 10.1007/s00381-012-1813-x. Epub 2012 Jun 4. Review.
2012
|
| 35 | ADAM9, FGFR2, MMP14
|
| MT1-MMP inactivates ADAM9 to regulate FGFR2 signaling and calvarial osteogenesis.
|
| Chan KM, Wong HL, Jin G, Liu B, Cao R, Cao Y, Lehti K, Tryggvason K, Zhou Z.
|
| Dev Cell 22(6):1176-90. doi: 10.1016/j.devcel.2012.04.014. Epub 2012 May 24.
2012
|
| 36 | FGFR2
|
| Fibroblast growth factor-2 maintains a niche-dependent population of self-renewing highly potent non-adherent mesenchymal progenitors through FGFR2c.
|
| Di Maggio N, Mehrkens A, Papadimitropoulos A, Schaeren S, Heberer M, Banfi A, Martin I.
|
| Stem Cells 30(7):1455-64. doi: 10.1002/stem.1106.
2012
|
| 37 | BBDS, FGFR2
|
| Bent bone dysplasia-FGFR2 type, a distinct skeletal disorder, has deficient canonical FGF signaling.
|
| Merrill AE, Sarukhanov A, Krejci P, Idoni B, Camacho N, Estrada KD, Lyons KM, Deixler H, Robinson H, Chitayat D, Curry CJ, Lachman RS, Wilcox WR, Krakow D.
|
| Am J Hum Genet 90(3):550-7. doi: 10.1016/j.ajhg.2012.02.005. Epub 2012 Mar 1.
2012
|
| 38 | FGFR2
|
| FGFR2 mutation confers a less drastic gain of function in mesenchymal stem cells than in fibroblasts.
|
| Yeh E, Atique R, Ishiy FA, Fanganiello RD, Alonso N, Matushita H, da Rocha KM, Passos-Bueno MR.
|
| Stem Cell Rev 8(3):685-95. doi: 10.1007/s12015-011-9327-6.
2012
|
| 39 | FGFR2, GRB2
|
| Inhibition of basal FGF receptor signaling by dimeric Grb2.
|
| Lin CC, Melo FA, Ghosh R, Suen KM, Stagg LJ, Kirkpatrick J, Arold ST, Ahmed Z, Ladbury JE.
|
| Cell 149(7):1514-24. doi: 10.1016/j.cell.2012.04.033.
2012
|
| 40 | FGFR2, NFKB1
|
| The breast cancer susceptibility gene product fibroblast growth factor receptor 2 serves as a scaffold for regulation of NF-κB signaling.
|
| Wei W, Liu W, Cassol CA, Zheng W, Asa SL, Ezzat S.
|
| Mol Cell Biol 32(22):4662-73. doi: 10.1128/MCB.00935-12. Epub 2012 Sep 17.
2012
|
| 41 | BCL2, BMP7, FGFR2, HOXC6, PDGFRA
|
| HOXC6 is deregulated in human head and neck squamous cell carcinoma and modulates Bcl-2 expression.
|
| Moon SM, Kim SA, Yoon JH, Ahn SG.
|
| J Biol Chem 287(42):35678-88. doi: 10.1074/jbc.M112.361675. Epub 2012 Aug 15.
2012
|
| 42 | FGFR2
|
| Identification and characterization of an inhibitory fibroblast growth factor receptor 2 (FGFR2) molecule, up-regulated in an Apert Syndrome mouse model.
|
| Wheldon LM, Khodabukus N, Patey SJ, Smith TG, Heath JK, Hajihosseini MK.
|
| Biochem J 436(1):71-81.
2011
|
| 43 | FGF10, FGFR2
|
| FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium.
|
| Vega-Hernández M, Kovacs A, De Langhe S, Ornitz DM.
|
| Development 138(15):3331-40.
2011
|
| 44 | FGFR2
|
| The receptor tyrosine kinase FGFR2b/KGFR controls early differentiation of human keratinocytes.
|
| Belleudi F, Purpura V, Torrisi MR.
|
| PLoS One 6(9):e24194. doi: 10.1371/journal.pone.0024194. Epub 2011 Sep 21.
2011
|
| 45 | FGFR2, NCAM1
|
| Co-localization of neural cell adhesion molecule and fibroblast growth factor receptor 2 in early embryo development.
|
| Vesterlund L, Töhönen V, Hovatta O, Kere J.
|
| Int J Dev Biol 55(3):313-9. doi: 10.1387/ijdb.103240lv.
2011
|
| 46 | FGFR1, FGFR2, FGFR3
|
| Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain.
|
| Furusho M, Kaga Y, Ishii A, Hébert JM, Bansal R.
|
| J Neurosci 31(13):5055-66. doi: 10.1523/JNEUROSCI.4800-10.2011.
2011
|
| 47 | FGFR1, FGFR2
|
| Overexpression of fibroblast growth factor receptors FGFR1 and FGFR2 in renal cell carcinoma.
|
| Tsimafeyeu I, Demidov L, Stepanova E, Wynn N, Ta H.
|
| Scand J Urol Nephrol 45(3):190-5. doi: 10.3109/00365599.2011.552436. Epub 2011 Feb 18.
2011
|
| 48 | FGFR1, FGFR2
|
| Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development.
|
| Sims-Lucas S, Cusack B, Baust J, Eswarakumar VP, Masatoshi H, Takeuchi A, Bates CM.
|
| Dev Dyn 240(1):240-9. doi: 10.1002/dvdy.22501.
2011
|
| 49 | FGFR2, FRS2
|
| Independent roles of Fgfr2 and Frs2alpha in ureteric epithelium.
|
| Sims-Lucas S, Cusack B, Eswarakumar VP, Zhang J, Wang F, Bates CM.
|
| Development 138(7):1275-80. doi: 10.1242/dev.062158. Epub 2011 Feb 24.
2011
|
| 50 | CRS5A, FGFR2
|
| Analysis of a gain-of-function FGFR2 Crouzon mutation provides evidence of loss of function activity in the etiology of cleft palate.
|
| Snyder-Warwick AK, Perlyn CA, Pan J, Yu K, Zhang L, Ornitz DM.
|
| Proc Natl Acad Sci U S A 107(6):2515-20. Epub 2010 Feb 1.PMID: 20133659 2010
|
| 51 | DEL11QD, DEL7P21, DEL9P, DUP5Q35, FGFR2, FGFR3, MSX2, TWIST
|
| Prevalence and complications of single-gene and chromosomal disorders in craniosynostosis.
|
| Wilkie AO, Byren JC, Hurst JA, Jayamohan J, Johnson D, Knight SJ, Lester T, Richards PG, Twigg SR, Wall SA.
|
| Pediatrics 126(2):e391-400. Epub 2010 Jul 19.PMID: 20643727 2010
|
| 52 | FGFR2
|
| Fibroblast growth factor receptor 2 and its role in caudal appendage and craniosynostosis.
|
| Sureka D, Hudgins L.
|
| J Craniofac Surg 21(5):1346-9. doi: 10.1097/SCS.0b013e3181ef2bab.
2010
|
| 53 | ACS1, FGFR2
|
| Rare mutations of FGFR2 causing apert syndrome: identification of the first partial gene deletion, and an Alu element insertion from a new subfamily.
|
| Bochukova EG, Roscioli T, Hedges DJ, Taylor IB, Johnson D, David DJ, Deininger PL, Wilkie AO.
|
| Hum Mutat 30(2):204-11.
2009
|
| 54 | FGFR2
|
| FGFR2 variants and breast cancer risk: fine-scale mapping using African American studies and analysis of chromatin conformation.
|
| Udler MS, Meyer KB, Pooley KA, Karlins E, Struewing JP, Zhang J, Doody DR, MacArthur S, Tyrer J, Pharoah PD, Luben R, Bernstein L, Kolonel LN, Henderson BE, Le Marchand L, Ursin G, Press MF, Brennan P, Sangrajrang S, Gaborieau V, Odefrey F, Shen CY, Wu PE, Wang HC, Kang D, Yoo KY, Noh DY, Ahn SH, Ponder BA, Haiman CA, Malone KE, Dunning AM, Ostrander EA, Easton DF; SEARCH Collaborators.
|
| Hum Mol Genet 18(9):1692-703. Epub 2009 Feb 17.
2009
|
| 55 | BSCGS1, FGFR2
|
| Novel FGFR2 deletion in a patient with Beare-Stevenson-like syndrome.
|
| Slavotinek A, Crawford H, Golabi M, Tao C, Perry H, Oberoi S, Vargervik K, Friez M.
|
| Am J Med Genet A 149A(8):1814-7. No abstract available. PMID: 19610084 2009
|
| 56 | FGFR2, HGS
|
| Hrs regulates the endocytic sorting of the fibroblast growth factor receptor 2b.
|
| Belleudi F, Leone L, Maggio M, Torrisi MR.
|
| Exp Cell Res 315(13):2181-91. Epub 2009 Apr 10.
2009
|
| 57 | BSCGS1, FGFR2
|
| Second case of Beare-Stevenson syndrome with an FGFR2 Ser372Cys mutation.
|
| Fonseca R, Costa-Lima MA, Cosentino V, Orioli IM.
|
| Am J Med Genet A 146(5):658-60. 2008
|
| 58 | FGFR2
|
| Drug-sensitive FGFR2 mutations in endometrial carcinoma.
|
| Dutt A, Salvesen HB, Chen TH, Ramos AH, Onofrio RC, Hatton C, Nicoletti R, Winckler W, Grewal R, Hanna M, Wyhs N, Ziaugra L, Richter DJ, Trovik J, Engelsen IB, Stefansson IM, Fennell T, Cibulskis K, Zody MC, Akslen LA, Gabriel S, Wong KK, Sellers WR, Meyerson M, Greulich H.
|
| Proc Natl Acad Sci U S A 105(25):8713-7. Epub 2008 Jun 13. 2008
|
| 59 | EFNB1, FGFR1, FGFR2, FGFR3, MSX2, RAB23, TWIST1
|
| Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations.
|
| Passos-Bueno MR, Serti Eacute AE, Jehee FS, Fanganiello R, Yeh E.
|
| Front Oral Biol 12:107-43. Review.
2008
|
| 60 | FGFR2, MAGEA3
|
| Fibroblast growth factor 2 and estrogen control the balance of histone 3 modifications targeting MAGE-A3 in pituitary neoplasia.
|
| Zhu X, Asa SL, Ezzat S.
|
| Clin Cancer Res 14(7):1984-96.PMID: 18381936 2008
|
| 61 | FGFR2
|
| Indirect recruitment of the signalling adaptor Shc to the fibroblast growth factor receptor 2 (FGFR2).
|
| Schüller AC, Ahmed Z, Levitt JA, Suen KM, Suhling K, Ladbury JE.
|
| Biochem J 416(2):189-99.PMID: 18840094 2008
|
| 62 | FGFR2, FRS2
|
| Extracellular point mutations in FGFR2 elicit unexpected changes in intracellular signalling.
|
| Ahmed Z, Schüller AC, Suhling K, Tregidgo C, Ladbury JE.
|
| Biochem J 413(1):37-49.PMID: 18373495 2008
|
| 63 | FGFR2
|
| Aberrant hypermethylation of the FGFR2 gene in human gastric cancer cell lines.
|
| Park S, Kim JH, Jang JH.
|
| Biochem Biophys Res Commun 357(4):1011-5. Epub 2007 Apr 18. 2007
|
| 64 | FGFR2
|
| A genome-wide association study identifies alleles in FGFR2 associated with risk of sporadic postmenopausal breast cancer.
|
| Hunter DJ, Kraft P, Jacobs KB, Cox DG, Yeager M, Hankinson SE, Wacholder S, Wang Z, Welch R, Hutchinson A, Wang J, Yu K, Chatterjee N, Orr N, Willett WC, Colditz GA, Ziegler RG, Berg CD, Buys SS, McCarty CA, Feigelson HS, Calle EE, Thun MJ, Hayes RB, Tucker M, Gerhard DS, Fraumeni JF Jr, Hoover RN, Thomas G, Chanock SJ.
|
| Nat Genet 39(7):870-4. Epub 2007 May 27. 2007
|
| 65 | FGF9, FGFR2
|
| Fibroblast growth factor receptor 2 regulates proliferation and Sertoli differentiation during male sex determination.
|
| Kim Y, Bingham N, Sekido R, Parker KL, Lovell-Badge R, Capel B.
|
| Proc Natl Acad Sci U S A 104(42):16558-63. Epub 2007 Oct 10. 2007
|
| 66 | FGFR2, LADD1, ALSG, FGF10
|
| Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation.
|
| Lew ED, Bae JH, Rohmann E, Wollnik B, Schlessinger J.
|
| Proc Natl Acad Sci U S A 104(50):19802-7. Epub 2007 Dec 3. 2007
|
| 67 | FGFR2
|
| The role of fibroblast growth factor receptor 2b in skin homeostasis and cancer development.
|
| Grose R, Fantl V, Werner S, Chioni AM, Jarosz M, Rudling R, Cross B, Hart IR, Dickson C.
|
| EMBO J 26(5):1268-78. Epub 2007 Feb 15.
2007
|
| 68 | ACS1, FGFR2
|
| Apert p.Ser252Trp mutation in FGFR2 alters osteogenic potential and gene expression of cranial periosteal cells.
|
| Fanganiello RD, Sertié AL, Reis EM, Yeh E, Oliveira NA, Bueno DF, Kerkis I, Alonso N, Cavalheiro S, Matsushita H, Freitas R, Verjovski-Almeida S, Passos-Bueno MR.
|
| Mol Med 13(7-8):422-42.
2007
|
| 69 | FGFR2, CRS5A, CRS6, CRS7B
|
| Mutation screening in patients with syndromic craniosynostoses indicates that a limited number of recurrent FGFR2 mutations accounts for severe forms of Pfeiffer syndrome.
|
| Lajeunie E, Heuertz S, El Ghouzzi V, Martinovic J, Renier D, Le Merrer M, Bonaventure J.
|
| Eur J Hum Genet 14(3):289-98. 2006
|
| 70 | FGFR2, FGFR3, FGF10, LADD1, LADD2, LADD3
|
| Mutations in different components of FGF signaling in LADD syndrome.
|
| Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nurnberg G, Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Becker C, Lehnerdt K, Cremers CW, Yuksel-Apak M, Nurnberg P, Kubisch C, Schlessinger J, van Bokhoven H, Wollnik B.
|
| Nat Genet 38(4):414-7. Epub 2006 Feb 26. 2006
|
| 71 | LADD1, FGFR2, LADD2, FGFR3, LADD3, FGF10
|
| Still more from FGFR: LADD syndrome caused by different mutations in FGFR and their ligands.
|
| Timmerman M.
|
| Clin Genet 70(1):17-9. No abstract available. 2006
|
| 72 | FGFR2
|
| Early-onset low-grade papillary carcinoma of the bladder associated with Apert syndrome and a germline FGFR2 mutation (Pro253Arg).
|
| Andreou A, Lamy A, Layet V, Cailliez D, Gobet F, Pfister C, Menard M, Frebourg T.
|
| Am J Med Genet A 140(20):2245-7. No abstract available. 2006
|
| 73 | FGFR2,NCAM1
|
| The neural cell adhesion molecule binds to fibroblast growth factor receptor 2.
|
| Christensen C, Lauridsen JB, Berezin V, Bock E, Kiselyov VV.
|
| FEBS Lett 580(14):3386-90. Epub 2006 May 11. 2006
|
| 74 | FGFR2, FGFR3, TWIST1, EFNB1, CRS, CRS2
|
| Clinical dividends from the molecular genetic diagnosis of craniosynostosis.
|
| Wilkie AO, Bochukova EG, Hansen RM, Taylor IB, Rannan-Eliya SV, Byren JC, Wall SA, Ramos L, Ven‰ncio M, Hurst JA, O'Rourke AW, Williams LJ, Seller A, Lester T.
|
| Am J Med Genet A 140(23):2631-9. Review. 2006
|
| 75 | FGFR2, ACS1
|
| Inhibition or activation of Apert syndrome FGFR2 (S252W) signaling by specific glycosaminoglycans.
|
| McDowell LM, Frazier BA, Studelska DR, Giljum K, Chen J, Liu J, Yu K, Ornitz DM, Zhang L.
|
| J Biol Chem 281(11):6924-30. Epub 2005 Dec 22. 2006
|
| 76 | FGF9, FGFR2, FGFR3
|
| Expression and possible function of fibroblast growth factor 9 (FGF9) and its cognate receptors FGFR2 and FGFR3 in postnatal and adult retina.
|
| Cinaroglu A, Ozmen Y, Ozdemir A, Ozcan F, Ergorul C, Cayirlioglu P, Hicks D, Bugra K.
|
| J Neurosci Res 79(3):329-39. 2005
|
| 77 | FGFR2, ACS1
|
| Gain-of-function amino acid substitutions drive positive selection of FGFR2 mutations in human spermatogonia.
|
| Goriely A, McVean GA, van Pelt AM, O'rourke AW, Wall SA, de Rooij DG, Wilkie AO.
|
| Proc Natl Acad Sci U S A 102(17):6051-6. Epub 2005 Apr 19. 2005
|
| 78 | TWIST1, FGFR2, ACS3, RUNX2
|
| A role for fibroblast growth factor receptor-2 in the altered osteoblast phenotype induced by Twist haploinsufficiency in the Saethre-Chotzen syndrome.
|
| Guenou H, Kaabeche K, Mee SL, Marie PJ.
|
| Hum Mol Genet 14(11):1429-39. Epub 2005 Apr 13. 2005
|
| 79 | CRS7B, FGFR2
|
| Vertebral anomalies and cartilaginous tracheal sleeve in three patients with Pfeiffer syndrome carrying the S351C FGFR2 mutation.
|
| Gonzales M, Heuertz S, Martinovic J, Delahaye S, Bazin A, Loget P, Pasquier L, Le Merrer M, Bonaventure J.
|
| Clin Genet 68(2):179-81. No abstract available. 2005
|
| 80 | CRS7C, FGFR2
|
| Familial scaphocephaly syndrome caused by a novel mutation in the FGFR2 tyrosine kinase domain.
|
| McGillivray G, Savarirayan R, Cox TC, Stojkoski C, McNeil R, Bankier A, Bateman JF, Roscioli T, Gardner RJ, Lamande SR.
|
| J Med Genet 42(8):656-62. No abstract available. 2005
|
| 81 | FGFR2
|
| Characterization of the intronic splicing silencers flanking FGFR2 exon IIIb.
|
| Wagner EJ, Baraniak AP, Sessions OM, Mauger D, Moskowitz E, Garcia-Blanco MA.
|
| J Biol Chem 280(14):14017-27. Epub 2005 Jan 31. 2005
|
| 82 | FGFR1,FGFR2
|
| The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells.
|
| Rosenthal R, Malek G, Salomon N, Peill-Meininghaus M, Coeppicus L, Wohlleben H, Wimmers S, Bowes Rickman C, Strauss O.
|
| Biochem Biophys Res Commun 337(1):241-7. 2005
|
| 83 | FGFR2
|
| A gain-of-function mutation of Fgfr2c demonstrates the roles of this receptor variant in osteogenesis.
|
| Eswarakumar VP, Horowitz MC, Locklin R, Morriss-Kay GM, Lonai P.
|
| Proc Natl Acad Sci U S A 101(34):12555-60. Epub 2004 Aug 17. 2004
|
| 84 | ACS1, CRS7B, CRS5A, FGFR2
|
| Biochemical analysis of pathogenic ligand-dependent FGFR2 mutations suggests distinct pathophysiological mechanisms for craniofacial and limb abnormalities.
|
| Ibrahimi OA, Zhang F, Eliseenkova AV, Itoh N, Linhardt RJ, Mohammadi M.
|
| Hum Mol Genet 13(19):2313-24. Epub 2004 Jul 28. 2004
|
| 85 | FGFR2, CRS7B
|
| Novel mutation in the tyrosine kinase domain of FGFR2 in a patient with Pfeiffer syndrome.
|
| Zankl A, Jaeger G, Bonafe L, Boltshauser E, Superti-Furga A.
|
| Am J Med Genet 131A(3):299-300. 2004
|
| 86 | FGFR2
|
| Molecular cloning, overexpression, and characterization of the ligand-binding D2 domain of fibroblast growth factor receptor.
|
| Hung KW, Kumar TK, Chi YH, Chiu IM, Yu C.
|
| Biochem Biophys Res Commun 317(1):253-8. 2004
|
| 87 | FGFR2, FGF10
|
| Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate.
|
| Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP.
|
| J Clin Invest 113(12):1692-700. 2004
|
| 88 | FGFR2, ACS1
|
| A soluble form of fibroblast growth factor receptor 2 (FGFR2) with S252W mutation acts as an efficient inhibitor for the enhanced osteoblastic differentiation caused by FGFR2 activation in Apert syndrome.
|
| Tanimoto Y, Yokozeki M, Hiura K, Matsumoto K, Nakanishi H, Matsumoto T, Marie PJ, Moriyama K.
|
| J Biol Chem 279(44):45926-34. Epub 2004 Aug 13. 2004
|
| 89 | FGF7, FGFR2, PAK4
|
| p21-activated protein kinase 4 (PAK4) interacts with the keratinocyte growth factor receptor and participates in keratinocyte growth factor-mediated inhibition of oxidant-induced cell death.
|
| Lu Y, Pan ZZ, Devaux Y, Ray P.
|
| J Biol Chem 278(12):10374-80. Epub 2003 Jan 15.
2003
|
| 90 | FGFR2, WDR11
|
| Recombination cluster around FGFR2-WDR11-HTPAPL locus on human chromosome 10q26.
|
| Katoh M, Katoh M.
|
| Int J Mol Med 11(5):579-83.PMID: 12684693 2003
|
| 91 | FGFR2, WDR11
|
| FGFR2 and WDR11 are neighboring oncogene and tumor suppressor gene on human chromosome 10q26.
|
| Katoh M, Katoh M.
|
| Int J Oncol 22(5):1155-9.PMID: 12684685 2003
|
| 92 | CRS7B, FGFR2
|
| Severe and mild phenotypes in Pfeiffer syndrome with splice acceptor mutations in exon IIIc of FGFR2.
|
| Teebi AS, Kennedy S, Chun K, Ray PN.
|
| Am J Med Genet 107(1):43-7. 2002
|
| 93 | BSCGS1, FGFR2
|
| Mutation in the FGFR2 gene in a Taiwanese patient with Beare-Stevenson cutis gyrata syndrome.
|
| Wang TJ, Huang CB, Tsai FJ, Wu JY, Lai RB, Hsiao M.
|
| Clin Genet 61(3):218-221. 2002
|
| 94 | ANBXL1, ANBXL2, FGFR2
|
| Abnormal sterol metabolism in a patient with Antley-Bixler syndrome and ambiguous genitalia.
|
| Kelley RI, Kratz LE, Glaser RL, Netzloff ML, Miller Wolf L, Jabs EW.
|
| Am J Med Genet 110(2):95-102. 2002
|
| 95 | FGFR1, FGFR2, FGFR3, MSX2, TWIST1
|
| Craniosynostosis associated with ocular and distal limb defects is very likely caused by mutations in a gene different from FGFR, TWIST, and MSX2.
|
| Passos-Bueno MR, Armelin LM, Alonso LG, Neustein I, Sertie AL, Abe K, Pavanello Rde C, Elkis LC, Koiffmann CP.
|
| Am J Med Genet 2002
|
| 96 | FGFR2
|
| Distinct craniofacial-skeletal-dermatological dysplasia in a patient with W290C mutation in FGFR2.
|
| Shotelersuk V, Ittiwut C, Srivuthana S, Mahatumarat C, Lerdlum S, Wacharasindhu S.
|
| Am J Med Genet 2002
|
| 97 | FGFR2, RUNX2
|
| Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast transcription factor, Cbfa1/Runx2.
|
| Xiao G, Jiang D, Gopalakrishnan R, Franceschi RT.
|
| J Biol Chem 277(39):36181-7. Epub 2002 Aug 28. 2002
|
| 98 | ACS1, FGFR2
|
| Structural basis for fibroblast growth factor receptor 2 activation in Apert syndrome.
|
| Ibrahimi OA, Eliseenkova AV, Plotnikov AN, Yu K, Ornitz DM, Mohammadi M.
|
| Proc Natl Acad Sci U S A 98(13):7182-7. 2001
|
| 99 | FGFR2
|
| Fibroblast growth factor receptor 2 (FGFR2): genomic sequence and variations.
|
| Ingersoll RG, Paznekas WA, Tran AK, Scott AF, Jiang G, Jabs EW.
|
| Cytogenet Cell Genet 94(3-4):121-6. 2001
|
| 100 | FGFR2
|
| Fibroblast growth factor receptor 2 (FGFR2) in brain neurons and retinal pigment epithelial cells act via stimulation of neuroendocrine L-type channels (Ca(v)1.3).
|
| Rosenthal R, Thieme H, Strauss O.
|
| FASEB J 15(6):970-7. 2001
|
| 101 | FGFR2
|
| Mutations in fibroblast growth factor receptor 2 and fibroblast growth factor receptor 3 genes associated with human gastric and colorectal cancers.
|
| Jang JH, Shin KH, Park JG.
|
| Cancer Res 61(9):3541-3. 2001
|
| 102 | FGFR2
|
| Polypyrimidine tract-binding protein represses splicing of a fibroblast growth factor receptor-2 gene alternative exon through exon sequences
|
| Le Guiner C, Plet A, Galiana D, Gesnel MC, Del Gatto-Konczak F, Breathnach R.
|
| J Biol Chem 276(47):43677-87. 2001
|
| 103 | CRS5A, CRS7B, FGFR2
|
| Paternal origin of FGFR2 mutations in sporadic cases of Crouzon syndrome and Pfeiffer syndrome.
|
| Glaser RL, Jiang W, Boyadjiev SA, Tran AK, Zachary AA, Van Maldergem L, Johnson D, Walsh S, Oldridge M, Wall SA, Wilkie AO, Jabs EW.
|
| Am J Hum Genet 66(3):768-77. 2000
|
| 104 | ACS1, FGFR2
|
| Genotype-phenotype analysis in Apert syndrome suggests opposite effects of the two recurrent mutations on syndactyly and outcome of craniofacial surgery.
|
| von Gernet S, Golla A, Ehrenfels Y, Schuffenhauer S, Fairley JD.
|
| Clin Genet 57(2):137-9. 2000
|
| 105 | CRS5A, FGFR2
|
| A novel mutation, Ala315Ser, in FGFR2: a gene-environment interaction leading to craniosynostosis?
|
| Johnson D, Wall SA, Mann S, Wilkie AO.
|
| Eur J Hum Genet 8(8):571-7. 2000
|
| 106 | FGFR2, CRS7B, CRS5A
|
| Clustering of FGFR2 gene mutations inpatients with Pfeiffer and Crouzon syndromes (FGFR2-associated craniosynostoses).
|
| Kress W, Collmann H, Busse M, Halliger-Keller B, Mueller CR.
|
| Cytogenet Cell Genet 91(1-4):134-7. 2000
|
| 107 | ACS1, FGFR2
|
| De novo alu-element insertions in FGFR2 identify a distinct pathological basis for apert syndrome.
|
| Oldridge M, et al.
|
| Am J Hum Genet 64(2):446-61. 1999
|
| 108 | FGFR2, CRS7B
|
| Analysis of the mutational spectrum of the FGFR2 gene in Pfeiffer syndrome.
|
| Cornejo-Roldan LR, et al.
|
| Hum Genet 104(5):425-31. 1999
|
| 109 | FGFR1, FGFR2, FGFR3
|
| Clinical spectrum of fibroblast growth factor receptor mutations.
|
| Passos-Bueno MR, et al.
|
| Hum Mutat 14(2):115-25. 1999
|
| 110 | FGFR2
|
| Genomic organization of the human fibroblast growth factor receptor 2 (FGFR2) gene and comparative analysis of the human FGFR gene family.
|
| Zhang Y, et al.
|
| Gene 230(1):69-79. 1999
|
| 111 | CRS11, FGFR2
|
| Ocular anterior chamber dysgenesis in craniosynostosis syndromes with a fibroblast growth factor receptor 2 mutation.
|
| Okajima K, et al.
|
| Am J Med Genet 85(2):160-70 1999
|
| 112 | ACS1, ACS3, CRS10, CRS11, DEL7P21, CRS5A, CRS5B, CRS6, CRS7B, CRS8, BSCGS1, CRSCNS, FGFR1, FGFR2, FGFR3, MSX2, SADDAN, TWIST1
|
| Craniosynostosis Syndromes: From Genes to Premature Fusion of Skull Bones.
|
| Hehr U, et al.
|
| Mol Genet Metab 68(2):139-151. No abstract available 1999
|
| 113 | CRS7B, FGFR2
|
| Pfeiffer syndrome caused by haploinsufficient mutation of FGFR2.
|
| Tsukuno M, Suzuki H, Eto Y.
|
| J Craniofac Genet Dev Biol 19(4):183-8. 1999
|
| 114 | CRS5A, FGFR2
|
| Novel mutation in the FGFR2 gene at the same codon as the Crouzon syndrome mutations in a severe Pfeiffer syndrome type 2 case.
|
| Schaefer F, Anderson C, Can B, Say B.
|
| Am J Med Genet 75(3):252-5. 1998
|
| 115 | FGFR2
|
| The mutations in FGFR2-associated craniosynostoses are clustered in five structural elements of immunoglobulin-like domain III of the receptor.
|
| Steinberger D, Vriend G, Mulliken JB, Muller U.
|
| Hum Genet 102(2):145-50. 1998
|
| 116 | FGFR1, FGFR2, FGFR3
|
| Conserved use of a non-canonical 5' splice site (/GA) in alternative splicing by fibroblast growth factor receptors 1, 2 and 3.
|
| Twigg SRF, et al.
|
| Hum Mol Genet 7 : 685-691. 1998
|
| 117 | BSCGS1, FGFR2
|
| FGFR2 gene mutation (Tyr375Cys) in a new case of Beare-Stevenson syndrome.
|
| Krepelova A, et al.
|
| Am J Med Genet 76 : 362-364. 1998
|
| 118 | FGFR2
|
| Activating mutations in the extracellular domain of the fibroblast growth factor receptor 2 function by disruption of the disulfide bond in the third immunoglobulin-like domain.
|
| Robertson SC, et al.
|
| Proc Natl Acad Sci U S A 95 : 4567-4572. 1998
|
| 119 | ANBXL1, FGFR2
|
| FGFR2 mutation associated with clinical manifestations consistent with Antley-Bixler syndrome.
|
| Chun K, et al.
|
| Am J Med Genet 77 : 219-224. 1998
|
| 120 | ACS1, FGFR2
|
| Presence of the Apert canonical S252W FGFR2 mutation in a patient without severe syndactyly.
|
| Passos-Bueno MR, et al.
|
| J Med Genet 35 : 677-679. 1998
|
| 121 | ACS1, FGFR2
|
| Apert syndrome mutations in fibroblast growth factor receptor 2 exhibit increased affinity for FGF ligand.
|
| Anderson J, et al.
|
| Hum Mol Genet 7 : 1475-1483. 1998
|
| 122 | CRS5A, CRS6, CRS7B, BSCGS1, FGFR2
|
| Mutation detection in FGFR2 craniosynostosis syndromes.
|
| Hollway GE, et al.
|
| Hum Genet 99 : 251-255. 1997
|
| 123 | ACS1, CRS5A, FGFR2
|
| Genotype-phenotype correlation for nucleotide substitutions in the IgII-IgIII linker of FGFR2.
|
| Oldridge M, et al.
|
| Hum Mol Genet 6 : 137-143. 1997
|
| 124 | CRS7B, FGFR2
|
| Trp290Cys mutation in exon IIIa of the fibroblast growth factor receptor 2 (FGFR2) gene is associated with Pfeiffer syndrome.
|
| Tartaglia M, Valeri S, Velardi F, Di Rocco C, Battaglia PA.
|
| Hum Genet 99(5):602-6. 1997
|
| 125 | CRS5A, FGFR2
|
| A novel mutation (a886g) in exon 5 of FGFR2 in members of a family with Crouzon phenotype and plagiocephaly.
|
| Steinberger D, Collmann H, Schmalenberger B, Muller U.
|
| J Med Genet 34(5):420-2. 1997
|
| 126 | CRS6, FGFR2
|
| Jackson-Weiss syndrome : identification of two novel FGFR2 missense mutations shared with Crouzon and Pfeiffer craniosynostotic disorders.
|
| Tartaglia M, Di Rocco C, Lajeunie E, Valeri S, Velardi F, Battaglia PA.
|
| Hum Genet 101(1):47-50. 1997
|
| 127 | ACS1, FGFR2
|
| A de novo Alu element insertion into an intron of FGFR2 causes Apert syndrome. (abstr)
|
| Oldridge M, et al.
|
| Am J Hum Genet 61 : A342. 1997
|
| 128 | CRS5A, CRS6, CRS7B, FGFR2
|
| FGFR2 exon IIIa and IIIc mutations in Crouzon, Jackson-Weiss, and Pfeiffer syndromes : evidence for missense changes, insertions, and a deletion due to alternative RNA splicing.
|
| Meyers GA, et al.
|
| Am J Hum Genet 58 : 491-498. 1996
|
| 129 | ACS1, FGFR2
|
| Exclusive paternal origin of new mutations in Apert syndrome.
|
| Moloney DM, et al.
|
| Nat Genet 13 : 48-53. 1996
|
| 130 | FGFR2, ACS1
|
| Differential effects of FGFR2 mutations on syndactyly and cleft palate in Apert syndrome.
|
| Slaney SF, et al.
|
| Am J Hum Genet 58 : 923-932. 1996
|
| 131 | CRS5A, FGFR2
|
| Constitutive receptor activation by Crouzon syndrome mutations in fibroblast growth factor receptor (FGFR) 2 and FGFR2/Neu chimeras.
|
| Galvin BD, et al.
|
| Proc Natl Acad Sci U S A 93 : 7894-7899. 1996
|
| 132 | CRS7A, CRS7B, FGFR1, FGFR2, FGFR3
|
| Identical mutations in three different fibroblast growth factor receptor genes in autosomal dominant craniosynostosis syndromes.
|
| Bellus GA, et al.
|
| Nat Genet 14 : 174-176. 1996
|
| 133 | CRS6, FGFR2
|
| Spectrum of craniosynostosis phenotypes associated with novel mutations at the fibroblast growth factor receptor 2 locus.
|
| Pulleyn LJ, et al.
|
| Eur J Hum Genet 4 : 283-291. 1996
|
| 134 | CRS5A, FGFR2
|
| Crouzon syndrome : previously unrecognized deletion, duplication, and point mutation within FGFR2 gene.
|
| Steinberger D, et al.
|
| Hum Mutat 8 : 386-390. 1996
|
| 135 | CRS5A, CRS6, CRS7B, BSCGS1, FGFR2
|
| FGFR2 mutation in clinically nonclassifiable autosomal dominant craniosynostosis with pronounced phenotypic variation.
|
| Steinberger D, Reinhartz T, Unsold R, Muller U.
|
| Am J Med Genet 66 : 81-86. 1996
|
| 136 | FGFR2, BSCGS1
|
| Fibroblast growth factor receptor 2 mutations in Beare-Stevenson cutis gyrata syndrome.
|
| Przylepa KA, Paznekas W, Zhang M, Golabi M, Bias W, Bamshad MJ, Carey JC, Hall BD, Stevenson R, Orlow S, Cohen MM Jr, Jabs EW.
|
| Nat Genet 13(4):492-4. 1996
|
| 137 | CRS7B, FGFR2
|
| FGFR2 mutations in Pfeiffer syndrome.
|
| Lajeunie E, et al.
|
| Nat Genet 9 : 108. 1995
|
| 138 | ACS1, CRS5A, FGFR2
|
| Apert syndrome results from localized mutations of FGFR2 and is allelic with Crouzon syndrome.
|
| Wilkie AOM, et al.
|
| Nat Genet 9 : 165-172. 1995
|
| 139 | FGFR2, CRS5A, CRS7B
|
| Identical mutations in the FGFR2 gene cause both Pfeiffer and Crouzon syndrome phenotypes.
|
| Rutland P, et al.
|
| Nat Genet 9 : 173-176. 1995
|
| 140 | CRS5A, FGFR2
|
| No evidence of genetic heterogeneity in Crouzon craniofacial dysostosis.
|
| Ma HW, et al.
|
| Hum Genet 96 : 731-735. 1995
|
| 141 | CRS5A, FGFR2
|
| Effect on splicing of a silent FGFR2 mutation in Crouzon syndrome.
|
| Li X, et al.
|
| Nat Genet 9 : 232-233. 1995
|
| 142 | CRS7A, CRS7B, FGFR1, FGFR2
|
| Mutations in FGFR1 and FGFR2 cause familial and sporadic Pfeiffer syndrome.
|
| Schell U, et al.
|
| Hum Mol Genet 4 : 323-328. 1995
|
| 143 | CRS5A, FGFR2
|
| Mutations in the third immunoglobulin domain of the fibroblast growth factor receptor-2 gene in Crouzon syndrome.
|
| Oldridge M, et al.
|
| Hum Mol Genet 4 : 1077-1082. 1995
|
| 144 | FGFR2, CRS5A
|
| Predisposition for cysteine substitutions in the immunoglobulin-like chain of FGFR2 in Crouzon syndrome.
|
| Steinberger D, et al.
|
| Hum Genet 96 : 113-115. 1995
|
| 145 | FGFR2, CRS5A, CRS6
|
| Novel FGFR2 mutations in Crouzon and Jackson-Weiss syndromes show allelic heterogeneity and phenotypic variability.
|
| Park WJ, et al.
|
| Hum Mol Genet 4 : 1229-1233. 1995
|
| 146 | CRS5A, FGFR2
|
| A Crouzon syndrome synonymous mutation activates a 5' splice site withinthe IIIC exon of the FGFR2 gene.
|
| Del Gatto F, et al.
|
| Genomics 27 : 558-559. 1995
|
| 147 | FGFR2, CRS5A, CRS6
|
| Crouzon syndrome : mutations in two spliceoforms of FGFR2 and a common point mutation shared with Jackson-Weiss syndrome.
|
| Gorry MC, et al.
|
| Hum Mol Genet 4 : 1387-1390. 1995
|
| 148 | FGFR2, ACS1
|
| Analysis of phenotypic features and FGFR2 mutations in Apert syndrome.
|
| Park WJ, et al.
|
| Am J Hum Genet 57 : 321-328. 1995
|
| 149 | FGFR2, CRS5A
|
| Mutations in the fibroblast growth factor receptor 2 gene cause Crouzon syndrome.
|
| Reardon W, et al.
|
| Nat Genet 8 : 98-103. 1994
|
| 150 | FGFR2, CRS5A, CRS6
|
| Jackson-Weiss and Crouzon syndromes are allelic with mutations in fibroblast growth factor receptor 2.
|
| Jabs EW, et al.
|
| Nat Genet 8 : 275-279. 1994
|
| 151 | FGFR1, FGFR2
|
| Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas.
|
| Yamaguchi F, et al.
|
| Proc Natl Acad Sci U S A 91 : 484-488. 1994
|
| 152 | FGFR2
|
| BEK, a receptor for multiple members of the fibroblast growth factor (FGF) family, maps to human chromosome 10q25.3-q26.
|
| Dionne CA, et al.
|
| Cytogenet Cell Genet 60 : 34-36. 1992
|
| 153 | FGFR1, FGFR2
|
| Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues.
|
| Luqmani YA, et al.
|
| Br J Cancer 66 : 273-280. 1992
|
| 154 | FGFR2
|
| K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinase.
|
| Katoh M, et al.
|
| Proc Natl Acad Sci U S A 89 : 2960-2964. 1992
|
| 155 | FGFR2
|
| Determination of ligand-binding specificity by alternative splicing: two distinct growth factor receptors encoded by a single gene.
|
| Miki T, Bottaro DP, Fleming TP, Smith CL, Burgess WH, Chan AM, Aaronson SA.
|
| Proc Natl Acad Sci U S A 89(1):246-50. 1992
|
| 156 | FGFR2
|
| Assignment by in situ hybridization of a fibroblast growth factor receptor gene to human chromosome band 10q26.
|
| Mattei MG, et al.
|
| Hum Genet 87 : 84-86. 1991
|
| 157 | FGFR2
|
| Related fibroblast growth factor receptor genes exist in the human genome.
|
| Houssaint E, et al.
|
| Proc Natl Acad Sci U S A 87 : 8180-8184. 1990
|