| 1 | FGFR1, LETM2, NSD3
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| Characteristics and Prognosis of 8p11.23-Amplified Squamous Lung Carcinomas
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| Voutsadakis IA.
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| J Clin Med. Feb 21;12(5):1711. doi: 10.3390/jcm12051711. 2023
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| 2 | FGF21, FGFR1, KLB
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| KLB, encoding β-Klotho, is mutated in patients with congenital hypogonadotropic hypogonadism.
|
| Xu C, Messina A, Somm E, Miraoui H, Kinnunen T, Acierno J Jr, Niederländer NJ, Bouilly J, Dwyer AA, Sidis Y, Cassatella D, Sykiotis GP, Quinton R, De Geyter C, Dirlewanger M, Schwitzgebel V, Cole TR, Toogood AA, Kirk JM, Plummer L, Albrecht U, Crowley WF Jr, Mohammadi M, Tena-Sempere M, Prevot V, Pitteloud N.
|
| EMBO Mol Med 9(10):1379-1397. doi: 10.15252/emmm.201607376.
2017
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| 3 | ECCL, FGFR1
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| Mosaic Activating Mutations in FGFR1 Cause Encephalocraniocutaneous Lipomatosis.
|
| Bennett JT, Tan TY, Alcantara D, Tétrault M, Timms AE, Jensen D, Collins S, Nowaczyk MJ, Lindhurst MJ, Christensen KM, Braddock SR, Brandling-Bennett H, Hennekam RC, Chung B, Lehman A, Su J, Ng S, Amor DJ; University of Washington Center for Mendelian Genomics; Care4Rare Canada Consortium, Majewski J, Biesecker LG, Boycott KM, Dobyns WB, O'Driscoll M, Moog U, McDonell LM.
|
| Am J Hum Genet 98(3):579-87. doi: 10.1016/j.ajhg.2016.02.006.
2016
|
| 4 | FGF21, FGFR1, MAP3K4
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| MEKK4 Signaling Regulates Sensory Cell Development and Function in the Mouse Inner Ear.
|
| Haque K, Pandey AK, Zheng HW, Riazuddin S, Sha SH, Puligilla C.
|
| J Neurosci 36(4):1347-61. doi: 10.1523/JNEUROSCI.1853-15.2016.
2016
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| 5 | FGFR1, ZMYM2
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| Diagnostic application of next-generation sequencing in ZMYM2-FGFR1 8p11 myeloproliferative syndrome: A case report.
|
| Wang Y, Wu X, Deng J, Yu H, Xu R, Zhu Z, Tu S, Hu Y.
|
| Cancer Biol Ther. Aug 2;17(8):785-9. doi: 10.1080/15384047.2016.1210727 2016
|
| 6 | FGFR1, FGFR2
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| Mesenchymal fibroblast growth factor receptor signaling regulates palatal shelf elevation during secondary palate formation.
|
| Yu K, Karuppaiah K, Ornitz DM.
|
| Dev Dyn 244(11):1427-38. doi: 10.1002/dvdy.24319. Epub 2015 Aug 24.
2015
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| 7 | ESYT1, ESYT2, ESYT3, FGFR1
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| Extended Synaptotagmin Interaction with the Fibroblast Growth Factor Receptor Depends on Receptor Conformation, Not Catalytic Activity.
|
| Tremblay MG, Herdman C, Guillou F, Mishra PK, Baril J, Bellenfant S, Moss T.
|
| J Biol Chem 290(26):16142-56. doi: 10.1074/jbc.M115.656918. Epub 2015 Apr 28. Erratum in: J Biol Chem. 2016 Feb 12;291(7):3173.
2015
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| 8 | DNM2, FGF1, FGF21, FGFR1
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| FGF21 promotes endothelial cell angiogenesis through a dynamin-2 and Rab5 dependent pathway.
|
| Yaqoob U, Jagavelu K, Shergill U, de Assuncao T, Cao S, Shah VH.
|
| PLoS One 9(5):e98130. doi: 10.1371/journal.pone.0098130.
2014
|
| 9 | FGFR1, RPS6KA3
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| RSK2 regulates endocytosis of FGF receptor 1 by phosphorylation on serine 789.
|
| Nadratowska-Wesolowska B, Haugsten EM, Zakrzewska M, Jakimowicz P, Zhen Y, Pajdzik D, Wesche J, Wiedlocha A.
|
| Oncogene 33(40):4823-36. doi: 10.1038/onc.2013.425. Epub 2013 Oct 21.
2014
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| 10 | CRS7A, CRS7C, FGFR1, FGFR2
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| FGFR1 and FGFR2 Mutations in Pfeiffer Syndrome.
|
| Chokdeemboon C, Mahatumarat C, Rojvachiranonda N, Tongkobpetch S, Suphapeetiporn K, Shotelersuk V.
|
| J Craniofac Surg 24(1):150-2. doi: 10.1097/SCS.0b013e3182646454.
2013
|
| 11 | FGFR1
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| NMR backbone assignments of the tyrosine kinase domain of human fibroblast growth factor receptor 1.
|
| Vajpai N, Schott AK, Vogtherr M, Breeze AL.
|
| Biomol NMR Assign iomol NMR Assign. 2013 Jan 17. [Epub ahead of print]
2013
|
| 12 | FGFR1
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| A rare case report of 8p11 myeloid and lymphoid neoplasm with FGFR1 abnormality in a young adult.
|
| Shaaban H, Dabu J, Al-Rabi K, Gauchan D, Guron G.
|
| Ann Hematol 92(2):285-6. doi: 10.1007/s00277-012-1562-7. Epub 2012 Sep 2. No abstract available.
2013
|
| 13 | FGFR1, FGFR3
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| Fibroblast growth factor receptors-1 and -3 play distinct roles in the regulation of bladder cancer growth and metastasis: implications for therapeutic targeting.
|
| Cheng T, Roth B, Choi W, Black PC, Dinney C, McConkey DJ.
|
| PLoS One 8(2):e57284. doi: 10.1371/journal.pone.0057284. Epub 2013 Feb 26.
2013
|
| 14 | FGFR1, NTRK2, QKI
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| Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma.
|
| Jones DT, Hutter B, Jäger N, Korshunov A, Kool M, Warnatz HJ, Zichner T, Lambert SR, Ryzhova M, Quang DA, Fontebasso AM, Stütz AM, Hutter S, Zuckermann M, Sturm D, Gronych J, Lasitschka B, Schmidt S, Seker-Cin H, Witt H, Sultan M, Ralser M, Northcott PA, Hovestadt V, Bender S, Pfaff E, Stark S, Faury D, Schwartzentruber J, Majewski J, Weber UD, Zapatka M, Raeder B, Schlesner M, Worth CL, Bartholomae CC, von Kalle C, Imbusch CD, Radomski S, Lawerenz C, van Sluis P, Koster J, Volckmann R, Versteeg R, Lehrach H, Monoranu C, Winkler B, Unterberg A, Herold-Mende C, Milde T, Kulozik AE, Ebinger M, Schuhmann MU, Cho YJ, Pomeroy SL, von Deimling A, Witt O, Taylor MD, Wolf S, Karajannis MA, Eberhart CG, Scheurlen W, Hasselblatt M, Ligon KL, Kieran MW, Korbel JO, Yaspo ML, Brors B, Felsberg J, Reifenberger G, Collins VP, Jabado N, Eils R, Lichter P, Pfister SM; International Cancer Genome Consortium PedBrain Tumor Project.
|
| Nat Genet 45(8):927-32. doi: 10.1038/ng.2682. Epub 2013 Jun 30.
2013
|
| 15 | FGFR1, HRTFDS
|
| FGFR1 mutations cause Hartsfield syndrome, the unique association of holoprosencephaly and ectrodactyly.
|
| Simonis N, Migeotte I, Lambert N, Perazzolo C, de Silva DC, Dimitrov B, Heinrichs C, Janssens S, Kerr B, Mortier G, Van Vliet G, Lepage P, Casimir G, Abramowicz M, Smits G, Vilain C.
|
| J Med Genet 50(9):585-92. doi: 10.1136/jmedgenet-2013-101603. Epub 2013 Jun 28.
2013
|
| 16 | FGFR1, GPNMB
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| GPNMB enhances bone regeneration by promoting angiogenesis and osteogenesis: potential role for tissue engineering bone.
|
| Hu X, Zhang P, Xu Z, Chen H, Xie X.
|
| J Cell Biochem 114(12):2729-37. doi: 10.1002/jcb.24621.
2013
|
| 17 | FGFR1, LRIT3
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| Leucine-rich repeat, immunoglobulin-like and transmembrane domain 3 (LRIT3) is a modulator of FGFR1.
|
| Kim SD, Liu JL, Roscioli T, Buckley MF, Yagnik G, Boyadjiev SA, Kim J.
|
| FEBS Lett 586(10):1516-21. doi: 10.1016/j.febslet.2012.04.010. Epub 2012 Apr 20. 2012
|
| 18 | FGFR1
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| Differential roles of fibroblast growth factor receptors (FGFR) 1, 2 and 3 in the regulation of S115 breast cancer cell growth.
|
| Tarkkonen KM, Nilsson EM, Kähkönen TE, Dey JH, Heikkilä JE, Tuomela JM, Liu Q, Hynes NE, Härkönen PL.
|
| PLoS One 7(11):e49970. doi: 10.1371/journal.pone.0049970. Epub 2012 Nov 21.
2012
|
| 19 | FGFR1, KAL2
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| Evidence that FGFR1 loss-of-function mutations may cause variable skeletal malformations in patients with Kallmann syndrome.
|
| Jarzabek K, Wolczynski S, Lesniewicz R, Plessis G, Kottler M.
|
| Adv Med Sci 57(2):314-21. doi: 10.2478/v10039-012-0036-4.
2012
|
| 20 | FGFR1
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| FGFR1 amplification and the progression of non-invasive to invasive breast cancer.
|
| Gru AA, Allred DC.
|
| Breast Cancer Res 14(6):116. [Epub ahead of print]
2012
|
| 21 | FGFR1
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| FGFR1 is amplified during the progression of in situ to invasive breast carcinoma.
|
| Jang MH, Kim EJ, Choi Y, Lee HE, Kim YJ, Kim JH, Kang E, Kim SW, Kim IA, Park SY.
|
| Breast Cancer Res 14(4):R115. [Epub ahead of print]
2012
|
| 22 | F2R, FGFR1
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| Characterization of PAR1 and FGFR1 expression in invasive breast carcinomas: Prognostic significance.
|
| Tiburcio M, Costa SM, DE Fatima Duarte M, Schmitt FC, Longatto Filho A.
|
| Oncol Lett 4(4):647-657. Epub 2012 Jul 17.
2012
|
| 23 | FGFR1, SDC4
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| Syndecan 4 regulates FGFR1 signaling in endothelial cells by directing macropinocytosis.
|
| Elfenbein A, Lanahan A, Zhou TX, Yamasaki A, Tkachenko E, Matsuda M, Simons M.
|
| Sci Signal 5(223):ra36. doi: 10.1126/scisignal.2002495.
2012
|
| 24 | FGFR1
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| Fibroblast growth factor 1 (FGFR1) modulation regulates repair capacity of oligodendrocyte progenitor cells following chronic demyelination.
|
| Zhou YX, Pannu R, Le TQ, Armstrong RC.
|
| Neurobiol Dis 45(1):196-205. doi: 10.1016/j.nbd.2011.08.004. Epub 2011 Aug 10.
2012
|
| 25 | FGFR1, PARK7
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| DJ-1 promotes angiogenesis and osteogenesis by activating FGF receptor-1 signaling.
|
| Kim JM, Shin HI, Cha SS, Lee CS, Hong BS, Lim S, Jang HJ, Kim J, Yang YR, Kim YH, Yun S, Rijal G, Lee-Kwon W, Seo JK, Gho YS, Ryu SH, Hur EM, Suh PG.
|
| Nat Commun 3:1296. doi: 10.1038/ncomms2313.
2012
|
| 26 | FGF21, FGFR1, FGFR3, MAPK3
|
| Fibroblast growth factor 21 (FGF21) inhibits chondrocyte function and growth hormone action directly at the growth plate.
|
| Wu S, Levenson A, Kharitonenkov A, De Luca F.
|
| J Biol Chem 287(31):26060-7. doi: 10.1074/jbc.M112.343707. Epub 2012 Jun 13.
2012
|
| 27 | FGFR1, FGFR3, TACC1, TACC3
|
| Transforming fusions of FGFR and TACC genes in human glioblastoma.
|
| Singh D, Chan JM, Zoppoli P, Niola F, Sullivan R, Castano A, Liu EM, Reichel J, Porrati P, Pellegatta S, Qiu K, Gao Z, Ceccarelli M, Riccardi R, Brat DJ, Guha A, Aldape K, Golfinos JG, Zagzag D, Mikkelsen T, Finocchiaro G, Lasorella A, Rabadan R, Iavarone A.
|
| Science 337(6099):1231-5. doi: 10.1126/science.1220834.
2012
|
| 28 | FGFR1, GZMB
|
| FGFR1 cleavage and nuclear translocation regulates breast cancer cell behavior.
|
| Chioni AM, Grose R.
|
| J Cell Biol 197(6):801-17. doi: 10.1083/jcb.201108077. Epub 2012 Jun 4.
2012
|
| 29 | FGFR1, TPR
|
| Identification of a novel partner gene, TPR, fused to FGFR1 in 8p11 myeloproliferative syndrome.
|
| Li F, Zhai YP, Tang YM, Wang LP, Wan PJ.
|
| Genes Chromosomes Cancer 51(9):890-7. doi: 10.1002/gcc.21973. Epub 2012 May 23.
2012
|
| 30 | FGFR1
|
| Agonist-induced formation of FGFR1 homodimers and signaling differ among members of the FGF family.
|
| Romero-Fernandez W, Borroto-Escuela DO, Tarakanov AO, Mudó G, Narvaez M, Pérez-Alea M, Agnati LF, Ciruela F, Belluardo N, Fuxe K.
|
| Biochem Biophys Res Commun 409(4):764-8. Epub 2011 May 20.
2011
|
| 31 | FGFR1, NEDD4
|
| Nedd4-1 binds and ubiquitylates activated FGFR1 to control its endocytosis and function.
|
| Persaud A, Alberts P, Hayes M, Guettler S, Clarke I, Sicheri F, Dirks P, Ciruna B, Rotin D.
|
| EMBO J 30(16):3259-73. doi: 10.1038/emboj.2011.234.
2011
|
| 32 | FGFR1, FGFR2, FGFR3
|
| Fibroblast growth factor signaling is required for the generation of oligodendrocyte progenitors from the embryonic forebrain.
|
| Furusho M, Kaga Y, Ishii A, Hébert JM, Bansal R.
|
| J Neurosci 31(13):5055-66. doi: 10.1523/JNEUROSCI.4800-10.2011.
2011
|
| 33 | FGFR1, FGFR2
|
| Overexpression of fibroblast growth factor receptors FGFR1 and FGFR2 in renal cell carcinoma.
|
| Tsimafeyeu I, Demidov L, Stepanova E, Wynn N, Ta H.
|
| Scand J Urol Nephrol 45(3):190-5. doi: 10.3109/00365599.2011.552436. Epub 2011 Feb 18.
2011
|
| 34 | FGFR1, FGFR2
|
| Fgfr1 and the IIIc isoform of Fgfr2 play critical roles in the metanephric mesenchyme mediating early inductive events in kidney development.
|
| Sims-Lucas S, Cusack B, Baust J, Eswarakumar VP, Masatoshi H, Takeuchi A, Bates CM.
|
| Dev Dyn 240(1):240-9. doi: 10.1002/dvdy.22501.
2011
|
| 35 | FGFR1
|
| Inhibition of fibroblast growth factor receptor 1 endocytosis promotes axonal branching of adult sensory neurons.
|
| Hausott B, Rietzler A, Vallant N, Auer M, Haller I, Perkhofer S, Klimaschewski L.
|
| Neuroscience 188:13-22. doi: 10.1016/j.neuroscience.2011.04.064. Epub 2011 May 7.
2011
|
| 36 | FGFR1, FGFR3
|
| Clathrin- and dynamin-independent endocytosis of FGFR3--implications for signalling.
|
| Haugsten EM, Zakrzewska M, Brech A, Pust S, Olsnes S, Sandvig K, Wesche J.
|
| PLoS One 6(7):e21708. doi: 10.1371/journal.pone.0021708. Epub 2011 Jul 14.
2011
|
| 37 | FGFR1, SCLLS, ZMYM2
|
| Constitutive Notch pathway activation in murine ZMYM2-FGFR1-induced T-cell lymphomas associated with atypical myeloproliferative disease.
|
| Ren M, Cowell JK.
|
| Blood Jun 23;117(25):6837-47. doi: 10.1182/blood-2010-07-295725. Epub 2011 Apr 28 2011
|
| 38 | FGFR1, LETM2, NSD3
|
| Inhibitor-sensitive FGFR1 amplification in human non-small cell lung cancer.
|
| Dutt A, Ramos AH, Hammerman PS, Mermel C, Cho J, Sharifnia T, Chande A, Tanaka KE, Stransky N, Greulich H, Gray NS, Meyerson M.
|
| PLoS One. ;6(6):e20351. doi: 10.1371/journal.pone.0020351. Epub 2011 Jun 7. 2011
|
| 39 | FGF8, FGFR1, KAL6, NIHH
|
| Nonsense mutations in FGF8 gene causing different degrees of human gonadotropin-releasing deficiency.
|
| Trarbach EB, Abreu AP, Silveira LF, Garmes HM, Baptista MT, Teles MG, Costa EM, Mohammadi M, Pitteloud N, Mendonca BB, Latronico AC.
|
| J Clin Endocrinol Metab 95(7):3491-6. Epub 2010 May 12.
2010
|
| 40 | CDH7, FGF8, FGFR1, GNRHR, IHH1, IHH2GNRH1, KAL1, KAL1, KAL2, KAL3, KAL4, KISS1R, PCC, PROK2, PROKR2, TAC3, TACR3
|
| Genetics basis for GnRH-dependent pubertal disorders in humans.
|
| Silveira LF, Trarbach EB, Latronico AC.
|
| Mol Cell Endocrinol 324(1-2):30-8. Epub 2010 Feb 25. Review.PMID: 20188792 2010
|
| 41 | FGFR1, OGD
|
| Osteoglophonic dysplasia: A 'common' mutation in a rare disease.
|
| Sow AJ, Ramli R, Latiff ZA, Ichikawa S, Gray AK, Nordin R, Abd Jabar MN, Primuharsa Putra SH, Siar CH, Econs MJ.
|
| Clin Genet 78(2):197-8. Epub 2010 Mar 5. No abstract available. PMID: 20236123 2010
|
| 42 | FGFR1, GRB14, PLCG1
|
| Grb14 inhibits FGF receptor signaling through the regulation of PLCγ recruitment and activation.
|
| Browaeys-Poly E, Blanquart C, Perdereau D, Antoine AF, Goenaga D, Luzy JP, Chen H, Garbay C, Issad T, Cailliau K, Burnol AF.
|
| FEBS Lett 584(21):4383-8. Epub 2010 Oct 8.
2010
|
| 43 | FGFR1, FLRT1, FLRT2, FLRT3
|
| Critical role of FLRT1 phosphorylation in the interdependent regulation of FLRT1 function and FGF receptor signalling.
|
| Wheldon LM, Haines BP, Rajappa R, Mason I, Rigby PW, Heath JK.
|
| PLoS One 5(4):e10264. 2010
|
| 44 | FGFR1, RAF1, SOS1
|
| Decreased expression of FGFR1, SOS1, RAF1 genes in cryptorchidism.
|
| Hadziselimovic NO, de Geyter Ch, Demougin P, Oakeley EJ, Hadziselimovic F.
|
| Urol Int 84(3):353-61. doi: 10.1159/000288242. Epub 2010 Apr 13.
2010
|
| 45 | CRKL, FGFR1
|
| Structural and functional basis of a role for CRKL in a fibroblast growth factor 8-induced feed-forward loop.
|
| Seo JH, Suenaga A, Hatakeyama M, Taiji M, Imamoto A.
|
| Mol Cell Biol 29(11):3076-87. Epub 2009 Mar 23. 2009
|
| 46 | FGFR1, FRS2, MTOR
|
| FGFR1 forms an FRS2-dependent complex with mTOR to regulate smooth muscle marker gene expression.
|
| Chen PY, Friesel R.
|
| Biochem Biophys Res Commun 382(2):424-9. Epub 2009 Mar 13.
2009
|
| 47 | E2F1, FGFR1
|
| Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1.
|
| Kanai M, Tashiro E, Maruki H, Minato Y, Imoto M.
|
| Gene 438(1-2):49-56. Epub 2009 Mar 19.
2009
|
| 48 | FGFR1, NFASC
|
| Analysis of non-canonical fibroblast growth factor receptor 1 (FGFR1) interaction reveals regulatory and activating domains of neurofascin.
|
| Kirschbaum K, Kriebel M, Kranz EU, Pötz O, Volkmer H.
|
| J Biol Chem 284(42):28533-42. Epub 2009 Aug 7.PMID: 19666467 2009
|
| 49 | FGFR1, HRTFDS
|
| Hartsfield holoprosencephaly-ectrodactyly syndrome in five male patients: further delineation and review.
|
| Vilain C, Mortier G, Van Vliet G, Dubourg C, Heinrichs C, de Silva D, Verloes A, Baumann C.
|
| Am J Med Genet A 149A(7):1476-81. doi: 10.1002/ajmg.a.32678. Review.
2009
|
| 50 | OFC6, IRF6, FGFR1, MSX1
|
| Identification of novel candidate genes associated with cleft lip and palate using array comparative genomic hybridisation.
|
| Osoegawa K, Vessere GM, Utami KH, Mansilla MA, Johnson MK, Riley BM, L'Heureux J, Pfundt R, Staaf J, van der Vliet WA, Lidral AC, Schoenmakers EF, Borg A, Schutte BC, Lammer EJ, Murray JC, de Jong PJ.
|
| J Med Genet 45(2):81-6. Epub 2007 Sep 14. 2008
|
| 51 | KAL2, KAL1, FGFR1
|
| Kallmann's syndrome: a comparison of the reproductive phenotypes in men carrying KAL1 and FGFR1/KAL2 mutations.
|
| Salenave S, Chanson P, Bry H, Pugeat M, Cabrol S, Carel JC, Murat A, Lecomte P, Brailly S, Hardelin JP, DodŽ C, Young J.
|
| J Clin Endocrinol Metab 93(3):758-63. Epub 2007 Dec 26. 2008
|
| 52 | EFNB1, FGFR1, FGFR2, FGFR3, MSX2, RAB23, TWIST1
|
| Genetics of craniosynostosis: genes, syndromes, mutations and genotype-phenotype correlations.
|
| Passos-Bueno MR, Serti Eacute AE, Jehee FS, Fanganiello R, Yeh E.
|
| Front Oral Biol 12:107-43. Review.
2008
|
| 53 | FGF8, FGFR1, KAL2, KAL4
|
| Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons.
|
| Chung WC, Moyle SS, Tsai PS.
|
| Endocrinology 149(10):4997-5003. Epub 2008 Jun 19.
2008
|
| 54 | ABL1, CPSF6, FGFR1, SFPQ
|
| The t(1;9)(p34;q34) and t(8;12)(p11;q15) fuse pre-mRNA processing proteins SFPQ (PSF) and CPSF6 to ABL and FGFR1.
|
| Hidalgo-Curtis C, Chase A, Drachenberg M, Roberts MW, Finkelstein JZ, Mould S, Oscier D, Cross NC, Grand FH.
|
| Genes Chromosomes Cancer 47(5):379-85.PMID: 18205209 2008
|
| 55 | FGFR1, SCLLS, ZMYM2
|
| The 8p11 myeloproliferative syndrome: review of literature and an illustrative case report.
|
| Goradia A, Bayerl M, Cornfield D.
|
| Int J Clin Exp Pathol 1(5):448-56.PMID: 18787627 2008
|
| 56 | FGFR1, NIHH
|
| A mutation in the fibroblast growth factor receptor 1 gene causes fully penetrant normosmic isolated hypogonadotropic hypogonadism.
|
| Xu N, Qin Y, Reindollar RH, Tho SP, McDonough PG, Layman LC.
|
| J Clin Endocrinol Metab 92(3):1155-8. Epub 2007 Jan 2. 2007
|
| 57 | SP1, FGFR1
|
| Sp1 is required for transcriptional activation of the fibroblast growth factor receptor 1 gene in neonatal cardiomyocytes.
|
| Seyed M, Dimario JX.
|
| Gene 400(1-2):150-7. Epub 2007 Jun 19. 2007
|
| 58 | FGFR1
|
| FGFR1 over-expression in primary rhabdomyosarcoma tumors is associated with hypomethylation of a 5' CpG island and abnormal expression of the AKT1, NOG, and BMP4 genes.
|
| Goldstein M, Meller I, Orr-Urtreger A.
|
| Genes Chromosomes Cancer 46(11):1028-38. 2007
|
| 59 | FGF2, FGFR1, IQGAP1, WASL
|
| IQGAP1 regulates cell motility by linking growth factor signaling to actin assembly.
|
| Benseñor LB, Kan HM, Wang N, Wallrabe H, Davidson LA, Cai Y, Schafer DA, Bloom GS.
|
| J Cell Sci 120(Pt 4):658-69. Epub 2007 Jan 30.
2007
|
| 60 | FGFR1
|
| FGFR-1 regulates angiogenesis through cytokines interleukin-4 and pleiotrophin.
|
| Magnusson PU, Dimberg A, Mellberg S, Lukinius A, Claesson-Welsh L.
|
| Blood 110(13):4214-22. Epub 2007 Sep 17.PMID: 17875810 2007
|
| 61 | FGFR1, OGD
|
| Extended mutational analyses of FGFR1 in osteoglophonic dysplasia.
|
| Farrow EG, Davis SI, Mooney SD, Beighton P, Mascarenhas L, Gutierrez YR, Pitukcheewanont P, White KE.
|
| Am J Med Genet A 140(5):537-9. No abstract available. 2006
|
| 62 | NIHH, FGFR1
|
| Mutations in fibroblast growth factor receptor 1 cause both Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism.
|
| Pitteloud N, Acierno JS Jr, Meysing A, Eliseenkova AV, Ma J, Ibrahimi OA, Metzger DL, Hayes FJ, Dwyer AA, Hughes VA, Yialamas M, Hall JE, Grant E, Mohammadi M, Crowley WF Jr.
|
| Proc Natl Acad Sci U S A 103(16):6281-6. Epub 2006 Apr 10. 2006
|
| 63 | FGFR1, KAL2
|
| Kallmann syndrome: somatic and germline mutations of the fibroblast growth factor receptor 1 gene in a mother and the son.
|
| Sato N, Ohyama K, Fukami M, Okada M, Ogata T.
|
| J Clin Endocrinol Metab 91(4):1415-8. Epub 2006 Jan 17. 2006
|
| 64 | FGFR1, KAL2
|
| Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes.
|
| Pitteloud N, Meysing A, Quinton R, Acierno JS Jr, Dwyer AA, Plummer L, Fliers E, Boepple P, Hayes F, Seminara S, Hughes VA, Ma J, Bouloux P, Mohammadi M, Crowley WF Jr.
|
| Mol Cell Endocrinol 254-255:60-9. Epub 2006 Jun 9. 2006
|
| 65 | FGFR1, KAL2
|
| Paediatric phenotype of Kallmann syndrome due to mutations of fibroblast growth factor receptor 1 (FGFR1).
|
| Zenaty D, Bretones P, Lambe C, Guemas I, David M, LŽger J, de Roux N.
|
| Mol Cell Endocrinol 254-255:78-83. Epub 2006 Jun 6. 2006
|
| 66 | CEP110, FGFR1
|
| A biphenotypic transformation of 8p11 myeloproliferative syndrome with CEP1/FGFR1 fusion gene.
|
| Yamamoto K, Kawano H, Nishikawa S, Yakushijin K, Okamura A, Matsui T.
|
| Eur J Haematol 77(4):349-54. Epub 2006 Jul 27. 2006
|
| 67 | FGFR1, NIHH
|
| Novel fibroblast growth factor receptor 1 mutations in patients with congenital hypogonadotropic hypogonadism with and without anosmia.
|
| Trarbach EB, Costa EM, Versiani B, de Castro M, Baptista MT, Garmes HM, de Mendonca BB, Latronico AC.
|
| J Clin Endocrinol Metab 91(10):4006-12. Epub 2006 Aug 1. Erratum in: J Clin Endocrinol Metab. 2008 May;93(5):2013. 2006
|
| 68 | FGFR1, OGD
|
| Mutations that cause osteoglophonic dysplasia define novel roles for FGFR1 in bone elongation.
|
| White KE, Cabral JM, Davis SI, Fishburn T, Evans WE, Ichikawa S, Fields J, Yu X, Shaw NJ, McLellan NJ, McKeown C, Fitzpatrick D, Yu K, Ornitz DM, Econs MJ.
|
| Am J Hum Genet 76(2):361-7. Epub 2004 Dec 28. 2005
|
| 69 | FGFR1, TRIM24
|
| 8p11 myeloproliferative syndrome with a novel t(7;8) translocation leading to fusion of the FGFR1 and TIF1 genes.
|
| Belloni E, Trubia M, Gasparini P, Micucci C, Tapinassi C, Confalonieri S, Nuciforo P, Martino B, Lo-Coco F, Pelicci PG, Di Fiore PP.
|
| Genes Chromosomes Cancer 42(3):320-5. 2005
|
| 70 | FGFR1, TWIST1
|
| Linkage disequilibrium analysis identifies an FGFR1 haplotype-tag SNP associated with normal variation in craniofacial shape.
|
| Coussens AK, van Daal A.
|
| Genomics 85(5):563-73. 2005
|
| 71 | ANK1, DEL8PP, FGFR1, KAL2, SPH1
|
| New case of contiguous gene syndrome at chromosome 8p11.2p12.
|
| Cau M, Congiu R, Origa R, Galanello R, Melis MA, Nucaro AL.
|
| Am J Med Genet A 136A(2):221-222. 2005
|
| 72 | FGFR1, TNS3
|
| Hypogonadotropic hypogonadism and cleft lip and palate caused by a balanced translocation producing haploinsufficiency for FGFR1.
|
| Kim HG, Herrick SR, Lemyre E, Kishikawa S, Salisz JA, Seminara S, MacDonald ME, Bruns GA, Morton CC, Quade BJ, Gusella JF.
|
| J Med Genet 42(8):666-72. No abstract available. 2005
|
| 73 | FGFR1,FGFR2
|
| The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells.
|
| Rosenthal R, Malek G, Salomon N, Peill-Meininghaus M, Coeppicus L, Wohlleben H, Wimmers S, Bowes Rickman C, Strauss O.
|
| Biochem Biophys Res Commun 337(1):241-7. 2005
|
| 74 | FGFR1, FGFR3, CRS10, CRS7A
|
| Proline to arginine mutations in FGF receptors 1 and 3 result in Pfeiffer and Muenke craniosynostosis syndromes through enhancement of FGF binding affinity.
|
| Ibrahimi OA, Zhang F, Eliseenkova AV, Linhardt RJ, Mohammadi M.
|
| Hum Mol Genet 13(1):69-78. Epub 2003 Nov 12. 2004
|
| 75 | FGFR1
|
| Correction of aberrant FGFR1 alternative RNA splicing through targeting of intronic regulatory elements.
|
| Bruno IG, Jin W, Cote GJ.
|
| Hum Mol Genet 13(21):2725. No abstract available. 2004
|
| 76 | FGFR1
|
| Genome-wide survey of human alternative pre-mRNA splicing with exon junction microarrays.
|
| Johnson JM, Castle J, Garrett-Engele P, Kan Z, Loerch PM, Armour CD, Santos R, Schadt EE, Stoughton R, Shoemaker DD.
|
| Science 302(5653):2141-4. 2003
|
| 77 | ANK1, DEL8PP, FGFR1, KAL2, SPH1
|
| Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome.
|
| Dode C, Levilliers J, Dupont JM, De Paepe A, Le Du N, Soussi-Yanicostas N, Coimbra RS, Delmaghani S, Compain-Nouaille S, Baverel F, Pecheux C, Le Tessier D, Cruaud C, Delpech M, Speleman F, Vermeulen S, Amalfitano A, Bachelot Y, Bouchard P, Cabrol S, Carel JC, Delemarre-van de Waal H, Goulet-Salmon B, Kottler ML, Richard O, Sanchez-Franco F, Saura R, Young J, Petit C, Hardelin JP.
|
| Nat Genet 33(4):463-5. Epub 2003 Mar 10. 2003
|
| 78 | FGFR1
|
| The 8p11 myeloproliferative syndrome: a distinct clinical entity caused by constitutive activation of FGFR1.
|
| Macdonald D, Reiter A, Cross NC.
|
| Acta Haematol 107(2):101-7. Review. 2002
|
| 79 | FGFR1, FGFR2, FGFR3, MSX2, TWIST1
|
| Craniosynostosis associated with ocular and distal limb defects is very likely caused by mutations in a gene different from FGFR, TWIST, and MSX2.
|
| Passos-Bueno MR, Armelin LM, Alonso LG, Neustein I, Sertie AL, Abe K, Pavanello Rde C, Elkis LC, Koiffmann CP.
|
| Am J Med Genet 2002
|
| 80 | FGFR1
|
| Fibroblast growth factor receptor-1 is expressed by endothelial progenitor cells.
|
| Burger PE, Coetzee S, McKeehan WL, Kan M, Cook P, Fan Y, Suda T, Hebbel RP, Novitzky N, Muller WA, Wilson EL.
|
| Blood 100(10):3527-35. 2002
|
| 81 | FGFR1
|
| Identification of four new translocations involving FGFR1 in myeloid disorders.
|
| Sohal J, Chase A, Mould S, Corcoran M, Oscier D, Iqbal S, Parker S, Welborn J, Harris RI, Martinelli G, Montefusco V, Sinclair P, Wilkins BS, van Den Berg H, Vanstraelen D, Goldman JM, Cross NC.
|
| Genes Chromosomes Cancer 32(2):155-63. 2001
|
| 82 | BCR, FGFR1
|
| Fusion of the BCR and the fibroblast growth factor receptor-I (FGFRI) genes as a result of t(8;22)(p11;q11) in a myeloproliferative disorder : the first fusion gene involving BCR but not ABL.
|
| Fioretos T, Panagopoulos J, Lassen C, Swedin A, Billstršm R, Isaksson M, Stršmbeck B, Olofsson T, Mitelman F, Johansson B.
|
| Genes Chromosomes Cancer 32 : 302-310. 2001
|
| 83 | FGFR1
|
| Clinical findings in a patient with FGFR1 P252R mutation and comparison with the literature.
|
| Roscioli T, Flanagan S, Kumar P, Masel J, Gattas M, Hyland VJ, Glass IA.
|
| Am J Med Genet 93(1):22-8. Review. 2000
|
| 84 | CEP110 , FGFR1
|
| FGFR1 is fused to the centrosome-associated protein CEP110 in the 8p12 stem cell myeloproliferative disorder with t(8;9)(p12;q33).
|
| Guasch G, Mack GJ, Popovici C, Dastugue N, Birnbaum D, Rattner JB, Pebusque MJ.
|
| Blood 95(5):1788-96. 2000
|
| 85 | FGFR1, SCLLS, ZMYM2
|
| The genomic structure of ZNF198 and location of breakpoints in the t(8;13) myeloproliferative syndrome.
|
| Kulkarni S, et al.
|
| Genomics 55 : 118-121. 1999
|
| 86 | FGFR1, SFRP1
|
| Differential expression assay of chromosome arm 8p genes identifies Frizzled-related (FRP1/FRZB) and Fibroblast Growth Factor Receptor 1 (FGFR1) as candidate breast cancer genes.
|
| Ugolini F, et al.
|
| Oncogene 18(10):1903-10. 1999
|
| 87 | FGFR1, FGFR2, FGFR3
|
| Clinical spectrum of fibroblast growth factor receptor mutations.
|
| Passos-Bueno MR, et al.
|
| Hum Mutat 14(2):115-25. 1999
|
| 88 | ACS1, ACS3, CRS10, CRS11, DEL7P21, CRS5A, CRS5B, CRS6, CRS7B, CRS8, BSCGS1, CRSCNS, FGFR1, FGFR2, FGFR3, MSX2, SADDAN, TWIST1
|
| Craniosynostosis Syndromes: From Genes to Premature Fusion of Skull Bones.
|
| Hehr U, et al.
|
| Mol Genet Metab 68(2):139-151. No abstract available 1999
|
| 89 | FGFR1, SCLLS, ZMYM2
|
| FGFR1 is fused with a novel zinc-finger gene, ZNF198, in the t(8;13) leukaemia/lymphoma syndrome.
|
| Xiao S, Nalabolu SR, Aster JC, Ma J, Abruzzo L, Jaffe ES, Stone R, Weissman SM, Hudson TJ, Fletcher JA.
|
| Nat Genet 18(1):84-7. 1998
|
| 90 | FGFR1, SCLLS, ZMYM2
|
| The t(8;13)(p11;q11-12) rearrangement associated with an atypical myeloproliferative disorder fuses the fibroblast growth factor receptor 1 gene to a novel gene RAMP.
|
| Smedley D, et al.
|
| Hum Mol Genet 7 : 637-642. 1998
|
| 91 | FGFR1, FGFR2, FGFR3
|
| Conserved use of a non-canonical 5' splice site (/GA) in alternative splicing by fibroblast growth factor receptors 1, 2 and 3.
|
| Twigg SRF, et al.
|
| Hum Mol Genet 7 : 685-691. 1998
|
| 92 | FGFR1, SCLLS, ZMYM2
|
| Fibroblast growth factor receptor 1 is fused to FIM in stem-cell myeloproliferative disorder with t(8;13)(p12;q12).
|
| Popovici C, et al.
|
| Proc Natl Acad Sci U S A 95 : 5712-5717. 1998
|
| 93 | FGFR1, SCLLS, ZMYM2
|
| t(6;8), t(8;9) and t(8;13) translocations associated with stem cell myeloproliferative disorders have close or identical breakpoints in chromosome region 8p11-12.
|
| Chaffanet M, et al.
|
| Oncogene 16 : 945-949. 1998
|
| 94 | FGFR1, SCLLS, ZMYM2
|
| Consistent fusion of ZNF198 to the fibroblast growth factor receptor-1 in the t(8;13)(p11;q12) myeloproliferative syndrome.
|
| Reiter A, Sohal J, Kulkarni S, Chase A, Macdonald DH, Aguiar RC, Goncalves C, Hernandez JM, Jennings BA, Goldman JM, Cross NC.
|
| Blood 92 : 1735-1742. 1998
|
| 95 | GTF2E2, NRG1, NEFL, FGFR1, POLB, PPP2CB, WRN
|
| Integrated map of the chromosome 8p12-p21 region, a region involved in human cancers and Werner syndrome.
|
| Imbert A, et al.
|
| Genomics 32 : 29-38. 1996
|
| 96 | FGFR1
|
| Structure of the FGF receptor tyrosine kinase domain reveals a novel autoinhibitory mechanism.
|
| Mohammadi M, et al.
|
| Cell 86 : 577-587. 1996
|
| 97 | CRS7A, CRS7B, FGFR1, FGFR2, FGFR3
|
| Identical mutations in three different fibroblast growth factor receptor genes in autosomal dominant craniosynostosis syndromes.
|
| Bellus GA, et al.
|
| Nat Genet 14 : 174-176. 1996
|
| 98 | FGFR1
|
| Identification of six novel autophosphorylation sites on fibroblast growth factor receptor 1 and elucidation of their importance in receptor activation and signal transduction.
|
| Mohammadi M, Dikic I, Sorokin A, Burgess WH, Jaye M, Schlessinger J.
|
| Mol Cell Biol 16(3):977-89.
1996
|
| 99 | CRS7A, CRS7B, FGFR1, FGFR2
|
| Mutations in FGFR1 and FGFR2 cause familial and sporadic Pfeiffer syndrome.
|
| Schell U, et al.
|
| Hum Mol Genet 4 : 323-328. 1995
|
| 100 | CEBPD, FGFR1
|
| Sequence identity locates CEBPD and FGFR1 to mapped human loci within proximal 8p.
|
| Wood S, et al.
|
| Cytogenet Cell Genet 70 : 188-191. 1995
|
| 101 | FGFR1
|
| Dinucleotide repeat polymorphism at the FGFR1 gene.
|
| Yu CE, et al.
|
| Hum Mol Genet 3 : 212. 1994
|
| 102 | CRS7A, FGFR1
|
| A common mutation in the fibroblast growth factor receptor 1 gene in Pfeiffer syndrome.
|
| Muenke M, et al.
|
| Nat Genet 8 : 269-274. 1994
|
| 103 | FGFR1, FGFR2
|
| Differential expression of two fibroblast growth factor-receptor genes is associated with malignant progression in human astrocytomas.
|
| Yamaguchi F, et al.
|
| Proc Natl Acad Sci U S A 91 : 484-488. 1994
|
| 104 | FGFR1, FGFR2
|
| Expression of basic fibroblast growth factor, FGFR1 and FGFR2 in normal and malignant human breast, and comparison with other normal tissues.
|
| Luqmani YA, et al.
|
| Br J Cancer 66 : 273-280. 1992
|
| 105 | FGFR1
|
| Differential splicing in the extracellular region of fibroblast growth factor receptor 1 generates receptor variants with different ligand-binding specificities.
|
| Werner S, Duan DS, de Vries C, Peters KG, Johnson DE, Williams LT.
|
| Mol Cell Biol 12(1):82-8. 1992
|
| 106 | FGFR1
|
| BEK and FLG, two receptors to members of FGF family, are amplified in subsets of human breast cancers.
|
| Adnane J, et al.
|
| Oncogene 6 : 659-663. 1991
|
| 107 | FGFR1
|
| The human fibroblast growth factor receptor genes: a common structural arrangement underlies the mechanisms for generating receptor forms that differ in their third immunoglobulin domain.
|
| Johnson DE, Lu J, Chen H, Werner S, Williams LT.
|
| Mol Cell Biol 11(9):4627-34. 1991
|
| 108 | FGFR1
|
| Alternative splicing generates at least five different isoforms of the human basic-FGF receptor.
|
| Eisemann A, Ahn JA, Graziani G, Tronick SR, Ron D.
|
| Oncogene 6(7):1195-202. Erratum in: Oncogene 1991 Dec;6(12):2379.
1991
|
| 109 | FGFR1
|
| A novel protein tyrosine kinase gene whose expression is modulated during endothelial cell differentiation.
|
| Ruta M, et al.
|
| Oncogene 3 : 9-15. 1988
|