Citations for
1FGF10, FGFR2, TBX4
Complex Compound Inheritance of Lethal Lung Developmental Disorders Due to Disruption of the TBX-FGF Pathway.
Karolak JA, Vincent M, Deutsch G, Gambin T, Cogné B, Pichon O, Vetrini F, Mefford HC, Dines JN, Golden-Grant K, Dipple K, Freed AS, Leppig KA, Dishop M, Mowat D, Bennetts B, Gifford AJ, Weber MA, Lee AF, Boerkoel CF, Bartell TM, Ward-Melver C, Besnard T, Petit F, Bache I, Tümer Z, Denis-Musquer M, Joubert M, Martinovic J, Bénéteau C, Molin A, Carles D, André G, Bieth E, Chassaing N, Devisme L, Chalabreysse L, Pasquier L, Secq V, Don M, Orsaria M, Missirian C, Mortreux J, Sanlaville D, Pons L, Küry S, Bézieau S, Liet JM, Joram N, Bihouée T, Scott DA, Brown CW, Scaglia F, Tsai AC, Grange DK, Phillips JA 3rd, Pfotenhauer JP, Jhangiani SN, Gonzaga-Jauregui CG, Chung WK, Schauer GM, Lipson MH, Mercer CL, van Haeringen A, Liu Q, Popek E, Coban Akdemir ZH, Lupski JR, Szafranski P, Isidor B, Le Caignec C, Stankiewicz P.
Am J Hum Genet 104(2):213-228. doi: 10.1016/j.ajhg.2018.12.010. Epub 2019 Jan 10. 2019
2FGF10, PAPPAS, PTLAH, RSPO2, TBX4
Homozygous Null TBX4 Mutations Lead to Posterior Amelia with Pelvic and Pulmonary Hypoplasia.
Kariminejad A, Szenker-Ravi E, Lekszas C, Tajsharghi H, Moslemi AR, Naert T, Tran HT, Ahangari F, Rajaei M, Nasseri M, Haaf T, Azad A, Superti-Furga A, Maroofian R, Ghaderi-Sohi S, Najmabadi H, Abbaszadegan MR, Vleminckx K, Nikuei P, Reversade B.
Am J Hum Genet 105(6):1294-1301. doi: 10.1016/j.ajhg.2019.10.013. Epub 2019 Nov 21. 2019
3DLX5, FGF10
The Dlx5-FGF10 signaling cascade controls cranial neural crest and myoblast interaction during oropharyngeal patterning and development.
Sugii H, Grimaldi A, Li J, Parada C, Vu-Ho T, Feng J, Jing J, Yuan Y, Guo Y, Maeda H, Chai Y.
Development 144(21):4037-4045. doi: 10.1242/dev.155176. Epub 2017 Oct 5. 2017
4FGF10, MRPS30
Evidence that the 5p12 Variant rs10941679 Confers Susceptibility to Estrogen-Receptor-Positive Breast Cancer through FGF10 and MRPS30 Regulation.
Ghoussaini M, French JD, Michailidou K, Nord S, Beesley J, Canisus S, Hillman KM, Kaufmann S, Sivakumaran H, Moradi Marjaneh M, Lee JS, Dennis J, Bolla MK, Wang Q, Dicks E, Milne RL, Hopper JL, Southey MC, Schmidt MK, Broeks A, Muir K, Lophatananon A, Fasching PA, Beckmann MW, Fletcher O, Johnson N, Sawyer EJ, Tomlinson I, Burwinkel B, Marme F, Guénel P, Truong T, Bojesen SE, Flyger H, Benitez J, González-Neira A, Alonso MR, Pita G, Neuhausen SL, Anton-Culver H, Brenner H, Arndt V, Meindl A, Schmutzler RK, Brauch H, Hamann U, Tessier DC, Vincent D, Nevanlinna H, Khan S, Matsuo K, Ito H, Dörk T, Bogdanova NV, Lindblom A, Margolin S, Mannermaa A, Kosma VM; kConFab/AOCS Investigators.
Am J Hum Genet 99(4):903-911. doi: 10.1016/j.ajhg.2016.07.017. 2016
5FGF10
Fgf10 is required for specification of non-sensory regions of the cochlear epithelium.
Urness LD, Wang X, Shibata S, Ohyama T, Mansour SL.
Dev Biol ev Biol. 2015 Jan 23. pii: S0012-1606(15)00035-4. doi: 10.1016/j.ydbio.2015.01.015. [Epub ahead of print] 2015
6FGF10
Fibroblast growth factor 10 protects neuron against oxygen-glucose deprivation injury through inducing heme oxygenase-1.
Li YH, Yang LY, Chen W, Li YK, Yuan HB.
Biochem Biophys Res Commun 456(1):225-31. doi: 10.1016/j.bbrc.2014.11.063. Epub 2014 Nov 22. 2015
7FGF10, LHX9
Lhx9 gene expression during early limb development in mice requires the FGF signalling pathway.
Yang Y, Wilson MJ.
Gene Expr Patterns 19(1-2):45-51. doi: 10.1016/j.gep.2015.07.002. Epub 2015 Jul 26. 2015
8FGF10
FGF10 promotes regional foetal cardiomyocyte proliferation and adult cardiomyocyte cell-cycle re-entry.
Rochais F, Sturny R, Chao CM, Mesbah K, Bennett M, Mohun TJ, Bellusci S, Kelly RG.
Cardiovasc Res 104(3):432-42. doi: 10.1093/cvr/cvu232. Epub 2014 Oct 24. 2014
9ETV1, EWSR1, FGF10
Etv1 and Ewsr1 cooperatively regulate limb mesenchymal Fgf10 expression in response to apical ectodermal ridge-derived fibroblast growth factor signal.
Yamamoto-Shiraishi Y, Higuchi H, Yamamoto S, Hirano M, Kuroiwa A.
Dev Biol 394(1):181-90. doi: 10.1016/j.ydbio.2014.07.022. Epub 2014 Aug 7. 2014
10FGF10, PBX1
Pbx1 activates Fgf10 in the mesenchyme of developing lungs.
Li W, Lin CY, Shang C, Han P, Xiong Y, Lin CJ, Yang J, Selleri L, Chang CP.
Genesis 52(5):399-407. doi: 10.1002/dvg.22764. Epub 2014 Mar 14. 2014
11FGF10, SDC4
Expression and roles of syndecan-4 in dental epithelial cell differentiation.
Yan Z, Chen G, Yang Y, Sun L, Jiang Z, Feng L, Yu M, Guo W, Tian W.
Int J Mol Med 34(5):1301-8. doi: 10.3892/ijmm.2014.1910. Epub 2014 Aug 19. 2014
12FGF10
Localized Fgf10 expression is not required for lung branching morphogenesis but prevents differentiation of epithelial progenitors.
Volckaert T, Campbell A, Dill E, Li C, Minoo P, De Langhe S.
Development 140(18):3731-42. doi: 10.1242/dev.096560. Epub 2013 Aug 7. 2013
13FGF10
Spatiotemporal expression of fibroblast growth factor 10 in human hindgut and anorectal development.
Yin SJ, Tang XB, Li FF, Zhang T, Yuan ZW, Wang WL, Bai YZ.
Cells Tissues Organs 198(1):28-34. doi: 10.1159/000351472. Epub 2013 Jun 13. 2013
14FGF10, RELA, SP3
Interactions between NF-κB and SP3 connect inflammatory signaling with reduced FGF-10 expression.
Carver BJ, Plosa EJ, Stinnett AM, Blackwell TS, Prince LS.
J Biol Chem 288(21):15318-25. doi: 10.1074/jbc.M112.447318. Epub 2013 Apr 4. 2013
15FGF10, FGF3
Direct and indirect roles of Fgf3 and Fgf10 in innervation and vascularisation of the vertebrate hypothalamic neurohypophysis.
Liu F, Pogoda HM, Pearson CA, Ohyama K, Löhr H, Hammerschmidt M, Placzek M.
Development 140(5):1111-22. doi: 10.1242/dev.080226. 2013
16FGF10, GATA3
Gata3 directly regulates early inner ear expression of Fgf10.
Economou A, Datta P, Georgiadis V, Cadot S, Frenz D, Maconochie M.
Dev Biol 374(1):210-22. doi: 10.1016/j.ydbio.2012.11.028. Epub 2012 Dec 3. 2013
17FGF10, FGF7
Fibroblast growth factors 7 and 10 are involved in ameloblastoma proliferation via the mitogen-activated protein kinase pathway.
Nakao Y, Mitsuyasu T, Kawano S, Nakamura N, Kanda S, Nakamura S.
Int J Oncol 43(5):1377-84. doi: 10.3892/ijo.2013.2081. Epub 2013 Aug 29. 2013
18FGF10, FGF8
Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium.
Watanabe Y, Zaffran S, Kuroiwa A, Higuchi H, Ogura T, Harvey RP, Kelly RG, Buckingham M.
Proc Natl Acad Sci U S A 109(45):18273-80. doi: 10.1073/pnas.1215360109. Epub 2012 Oct 23. 2012
19FGF10
Fibroblast growth factor 10 in human ovaries.
Oron G, Fisch B, Zhang XY, Gabbay-Benziv R, Kessler-Icekson G, Krissi H, Ben-Haroush A, Ao A, Abir R.
Reprod Biomed Online 25(4):396-401. doi: 10.1016/j.rbmo.2012.07.002. Epub 2012 Jul 20. 2012
20FGF10, ISL1
ISL1 directly regulates FGF10 transcription during human cardiac outflow formation.
Golzio C, Havis E, Daubas P, Nuel G, Babarit C, Munnich A, Vekemans M, Zaffran S, Lyonnet S, Etchevers HC.
PLoS One 7(1):e30677. doi: 10.1371/journal.pone.0030677. Epub 2012 Jan 27. 2012
21FGF10, TBX4, TBX5
Multiple roles and interactions of Tbx4 and Tbx5 in development of the respiratory system.
Arora R, Metzger RJ, Papaioannou VE.
PLoS Genet 8(8):e1002866. doi: 10.1371/journal.pgen.1002866. Epub 2012 Aug 2. 2012
22FGF10
Distinct expression patterns of Sulf1 and Hs6st1 spatially regulate heparan sulfate sulfation during prostate development.
Buresh-Stiemke RA, Malinowski RL, Keil KP, Vezina CM, Oosterhof A, Van Kuppevelt TH, Marker PC.
Dev Dyn 241(12):2005-13. doi: 10.1002/dvdy.23886. Epub 2012 Nov 5. 2012
23FGF10
FGF10 controls the patterning of the tracheal cartilage rings via Shh.
Sala FG, Del Moral PM, Tiozzo C, Alam DA, Warburton D, Grikscheit T, Veltmaat JM, Bellusci S.
Development 138(2):273-82. Epub 2010 Dec 9. 2011
24FGF10
Fibroblast growth factor 10 regulates Meckel's cartilage formation during early mandibular morphogenesis in rats.
Terao F, Takahashi I, Mitani H, Haruyama N, Sasano Y, Suzuki O, Takano-Yamamoto T.
Dev Biol 350(2):337-47. Epub 2010 Dec 11. 2011
25BARX2, FGF10
Barx2 and Fgf10 regulate ocular glands branching morphogenesis by controlling extracellular matrix remodeling.
Tsau C, Ito M, Gromova A, Hoffman MP, Meech R, Makarenkova HP.
Development 138(15):3307-17. 2011
26FGF10, FGFR2
FGF10/FGFR2b signaling is essential for cardiac fibroblast development and growth of the myocardium.
Vega-Hernández M, Kovacs A, De Langhe S, Ornitz DM.
Development 138(15):3331-40. 2011
27FGF10, FGF3
Redundant and dosage sensitive requirements for Fgf3 and Fgf10 in cardiovascular development.
Urness LD, Bleyl SB, Wright TJ, Moon AM, Mansour SL.
Dev Biol 356(2):383-97. Epub 2011 Jun 12. 2011
28FGF10
Fibroblast growth factor 10 haploinsufficiency causes chronic obstructive pulmonary disease.
Klar J, Blomstrand P, Brunmark C, Badhai J, Hĺkansson HF, Brange CS, Bergendal B, Dahl N.
J Med Genet 48(10):705-9. doi: 10.1136/jmedgenet-2011-100166. Epub 2011 Jul 8. 2011
29ELAVL1, FGF10, TBX4
HuR controls lung branching morphogenesis and mesenchymal FGF networks.
Sgantzis N, Yiakouvaki A, Remboutsika E, Kontoyiannis DL.
Dev Biol 354(2):267-79. doi: 10.1016/j.ydbio.2011.04.003. Epub 2011 Apr 16. 2011
30FGF10, FGF3, WNT8A
FGF signaling regulates otic placode induction and refinement by controlling both ectodermal target genes and hindbrain Wnt8a.
Urness LD, Paxton CN, Wang X, Schoenwolf GC, Mansour SL.
Dev Biol 340(2):595-604. Epub 2010 Feb 18. 2010
31ALSG, FGF10
An intronic alteration of the fibroblast growth factor 10 gene causing ALSG-(aplasia of lacrimal and salivary glands) syndrome.
Scheckenbach K, Balz V, Wagenmann M, Hoffmann TK.
BMC Med Genet 9:114. 2008
32FGF10
Investigation of FGF10 as a candidate gene in patients with anorectal malformations and exstrophy of the cloaca.
Krüger V, Khoshvaghti M, Reutter H, Vogt H, Boemers TM, Ludwig M.
Pediatr Surg Int 24(8):893-7. Epub 2008 Jun 28. 2008
33FGF10
Fgf10 regulates hepatopancreatic ductal system patterning and differentiation.
Dong PD, Munson CA, Norton W, Crosnier C, Pan X, Gong Z, Neumann CJ, Stainier DY.
Nat Genet 39(3):397-402. Epub 2007 Jan 28. 2007
34FGF10, ALSG
FGF10 missense mutations in aplasia of lacrimal and salivary glands (ALSG).
Entesarian M, Dahlqvist J, Shashi V, Stanley CS, Falahat B, Reardon W, Dahl N.
Eur J Hum Genet 15(3):379-82. Epub 2007 Jan 10. 2007
35FGF10
Fibroblast growth factor-10 prevents H2O2-induced cell cycle arrest by regulation of G1 cyclins and cyclin dependent kinases.
Upadhyay D, Chang W, Wei K, Gao M, Rosen GD.
FEBS Lett 581(2):248-52. Epub 2006 Dec 18. 2007
36FGFR2, LADD1, ALSG, FGF10
Structural basis for reduced FGFR2 activity in LADD syndrome: Implications for FGFR autoinhibition and activation.
Lew ED, Bae JH, Rohmann E, Wollnik B, Schlessinger J.
Proc Natl Acad Sci U S A 104(50):19802-7. Epub 2007 Dec 3. 2007
37CTTN, FGF10, FGF7
Cortactin involvement in the keratinocyte growth factor and fibroblast growth factor 10 promotion of migration and cortical actin assembly in human keratinocytes.
Ceccarelli S, Cardinali G, Aspite N, Picardo M, Marchese C, Torrisi MR, Mancini P.
Exp Cell Res 313(9):1758-77. Epub 2007 Mar 24. 2007
38FGF10, SPRY2
FGF 10 and Sprouty 2 modulate trophoblast invasion and branching morphogenesis.
Natanson-Yaron S, Anteby EY, Greenfield C, Goldman-Wohl D, Hamani Y, Hochner-Celnikier D, Yagel S.
Mol Hum Reprod 13(7):511-9. Epub 2007 May 12. 2007
39ALSG, FGF10
Lacrimo-auriculo-dento-digital syndrome is caused by reduced activity of the fibroblast growth factor 10 (FGF10)-FGF receptor 2 signaling pathway.
Shams I, Rohmann E, Eswarakumar VP, Lew ED, Yuzawa S, Wollnik B, Schlessinger J, Lax I.
Mol Cell Biol 27(19):6903-12. Epub 2007 Aug 6. 2007
40FGFR2, FGFR3, FGF10, LADD1, LADD2, LADD3
Mutations in different components of FGF signaling in LADD syndrome.
Rohmann E, Brunner HG, Kayserili H, Uyguner O, Nurnberg G, Lew ED, Dobbie A, Eswarakumar VP, Uzumcu A, Ulubil-Emeroglu M, Leroy JG, Li Y, Becker C, Lehnerdt K, Cremers CW, Yuksel-Apak M, Nurnberg P, Kubisch C, Schlessinger J, van Bokhoven H, Wollnik B.
Nat Genet 38(4):414-7. Epub 2006 Feb 26. 2006
41LADD1, FGFR2, LADD2, FGFR3, LADD3, FGF10
Still more from FGFR: LADD syndrome caused by different mutations in FGFR and their ligands.
Timmerman M.
Clin Genet 70(1):17-9. No abstract available. 2006
42ALSG, FGF10
Mutations in the gene encoding fibroblast growth factor 10 are associated with aplasia of lacrimal and salivary glands.
Entesarian M, Matsson H, Klar J, Bergendal B, Olson L, Arakaki R, Hayashi Y, Ohuchi H, Falahat B, Bolstad AI, Jonsson R, Wahren-Herlenius M, Dahl N.
Nat Genet 37(2):125-7. Epub 2005 Jan 16. 2005
43FGF7, FGF10
Fibroblast growth factors 7 and 10 are expressed in the human embryonic pancreatic mesenchyme and promote the proliferation of embryonic pancreatic epithelial cells.
Ye F, Duvillie B, Scharfmann R.
Diabetologia 48(2):277-81. Epub 2005 Feb 3. 2005
44FGF7, FGF10, FGF22, FGFBP1
The fibroblast growth factor binding protein is a novel interaction partner of FGF-7, FGF-10 and FGF-22 and regulates FGF activity: implications for epithelial repair.
Beer HD, Bittner M, Niklaus G, Munding C, Max N, Goppelt A, Werner S.
Oncogene 24(34):5269-77. 2005
45FGF10, FGF22, FGF7
Comparative genomics on FGF7, FGF10, FGF22 orthologs, and identification of fgf25.
Katoh Y, Katoh M.
Int J Mol Med 16(4):767-70. 2005
46FGF1, FGF2, FGF3, FGF4, FGF5, FGF6, FGF7, FGF8, FGF9, FGF10, FGF11, FGF12, FGF13, FGF14, FGF16, FGF17, FGF18, FGF19, FGF20, FGF21, FGF22, FGF23
Evolution of the Fgf and Fgfr gene families.
Itoh N, Ornitz DM.
Trends Genet 20(11):563-9. 2004
47FGFR2, FGF10
Disruption of Fgf10/Fgfr2b-coordinated epithelial-mesenchymal interactions causes cleft palate.
Rice R, Spencer-Dene B, Connor EC, Gritli-Linde A, McMahon AP, Dickson C, Thesleff I, Rice DP.
J Clin Invest 113(12):1692-700. 2004
48FGF10
FGF-10 is expressed at low levels in the human prostate.
Ropiquet F, Giri D, Kwabi-Addo B, Schmidt K, Ittmann M.
Prostate 44(4):334-8. 2000
49FGF10
Fgf10 is essential for limb and lung formation.
Sekine K, Ohuchi H, Fujiwara M, Yamasaki M, Yoshizawa T, Sato T, Yagishita N, Matsui D, Koga Y, Itoh N, Kato S.
Nat Genet 21 : 138-141. 1999
50FGF2, FGF8, FGF10
Fibroblast growth factor receptor 2 (FGFR2)-mediated reciprocal regulation loop between FGF8 and FGF10 is essential for limb induction.
Xu X, et al.
Development 125(4):753-65. 1998
51FGF10
Structure and expression of human fibroblast growth factor-10.
Emoto H, Tagashira S, Mattei MG, Yamasaki M, Hashimoto G, Katsumata T, Negoro T, Nakatsuka M, Birnbaum D, Coulier F, Itoh N.
J Biol Chem 272(37):23191-4. 1997
52FGF8, FGF10
The mesenchymal factor, FGF10, initiates and maintains the outgrowth of the chick limb bud through interaction with FGF8, an apical ectodermal factor.
Ohuchi H, et al.
Development 124 : 2235-2244. 1997