1 | FERMT3
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| Structure and lipid-binding properties of the kindlin-3 pleckstrin homology domain.
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| Ni T, Kalli AC, Naughton FB, Yates LA, Naneh O, Kozorog M, Anderluh G, Sansom MS, Gilbert RJ.
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| Biochem J 474(4):539-556. doi: 10.1042/BCJ20160791. Epub 2016 Dec 14.
2017
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2 | FERMT3, LAD3
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| Adaptive immune defects in a patient with leukocyte adhesion deficiency type III with a novel mutation in FERMT3.
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| Suratannon N, Yeetong P, Srichomthong C, Amarinthnukrowh P, Chatchatee P, Sosothikul D, van Hagen PM, van der Burg M, Wentink M, Driessen GJ, Suphapeetiporn K, Shotelersuk V.
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| Pediatr Allergy Immunol 27(2):214-7. doi: 10.1111/pai.12485. Epub 2015 Oct 22. No abstract available.
2016
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3 | FERMT3
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| NMR Characterization and Membrane Interactions of the Loop Region of Kindlin-3 F1 Subdomain.
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| Chua GL, Tan SM, Bhattacharjya S.
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| PLoS One 11(4):e0153501. doi: 10.1371/journal.pone.0153501. eCollection 2016.
2016
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4 | FERMT3, ITGB3
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| Site-specific phosphorylation of kindlin-3 protein regulates its capacity to control cellular responses mediated by integrin αIIbβ3.
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| Bialkowska K, Byzova TV, Plow EF.
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| J Biol Chem 290(10):6226-42. doi: 10.1074/jbc.M114.634436. Epub 2015 Jan 21.
2015
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5 | FERMT3, LAD3
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| A new mutation in the KINDLIN-3 gene ablates integrin-dependent leukocyte, platelet, and osteoclast function in a patient with leukocyte adhesion deficiency-III.
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| Crazzolara R, Maurer K, Schulze H, Zieger B, Zustin J, Schulz AS.
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| Pediatr Blood Cancer 62(9):1677-9. doi: 10.1002/pbc.25537. Epub 2015 Apr 8.
2015
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6 | FERMT3
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| Kindlin-3 interacts with the ribosome and regulates c-Myc expression required for proliferation of chronic myeloid leukemia cells.
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| Qu J, Ero R, Feng C, Ong LT, Tan HF, Lee HS, Ismail MH, Bu WT, Nama S, Sampath P, Gao YG, Tan SM.
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| Sci Rep 5:18491. doi: 10.1038/srep18491.
2015
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7 | FERMT3
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| Minimal amounts of kindlin-3 suffice for basal platelet and leukocyte functions in mice.
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| Klapproth S, Moretti FA, Zeiler M, Ruppert R, Breithaupt U, Mueller S, Haas R, Mann M, Sperandio M, Fässler R, Moser M.
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| Blood 126(24):2592-600. doi: 10.1182/blood-2015-04-639310. Epub 2015 Oct 5.
2015
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8 | FERMT3
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| Kindlin-3-mediated integrin adhesion is dispensable for quiescent but essential for activated hematopoietic stem cells.
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| Ruppert R, Moser M, Sperandio M, Rognoni E, Orban M, Liu WH, Schulz AS, Oostendorp RA, Massberg S, Fässler R.
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| J Exp Med 212(9):1415-32. doi: 10.1084/jem.20150269. Epub 2015 Aug 17.
2015
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9 | FERMT3
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| Kindlin-3 enhances breast cancer progression and metastasis by activating Twist-mediated angiogenesis.
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| Sossey-Alaoui K, Pluskota E, Davuluri G, Bialkowska K, Das M, Szpak D, Lindner DJ, Downs-Kelly E, Thompson CL, Plow EF.
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| FASEB J 28(5):2260-71. doi: 10.1096/fj.13-244004. Epub 2014 Jan 27.
2014
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10 | FERMT3, ITGB2
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| The kindlin 3 pleckstrin homology domain has an essential role in lymphocyte function-associated antigen 1 (LFA-1) integrin-mediated B cell adhesion and migration.
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| Hart R, Stanley P, Chakravarty P, Hogg N.
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| J Biol Chem 288(21):14852-62. doi: 10.1074/jbc.M112.434621. Epub 2013 Apr 17.
2013
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11 | FERMT3
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| Kindlin-3 regulates integrin activation and adhesion reinforcement of effector T cells.
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| Moretti FA, Moser M, Lyck R, Abadier M, Ruppert R, Engelhardt B, Fässler R.
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| Proc Natl Acad Sci U S A 110(42):17005-10. doi: 10.1073/pnas.1316032110. Epub 2013 Oct 2.
2013
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12 | FERMT3
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| The integrin coactivator Kindlin-3 is not required for lymphocyte diapedesis.
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| Cohen SJ, Gurevich I, Feigelson SW, Petrovich E, Moser M, Shakhar G, Fassler R, Alon R.
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| Blood 122(15):2609-17. doi: 10.1182/blood-2013-04-495036. Epub 2013 Aug 26.
2013
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13 | FERMT3, ITGB2
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| Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during inflammation.
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| Dixit N, Kim MH, Rossaint J, Yamayoshi I, Zarbock A, Simon SI.
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| J Immunol 189(12):5954-64. doi: 10.4049/jimmunol.1201638. Epub 2012 Nov 9.
2012
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14 | FERMT3
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| Regulation of cell adhesion and migration by Kindlin-3 cleavage by calpain.
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| Zhao Y, Malinin NL, Meller J, Ma Y, West XZ, Bledzka K, Qin J, Podrez EA, Byzova TV.
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| J Biol Chem 287(47):40012-20. doi: 10.1074/jbc.M112.380469. Epub 2012 Sep 25.
2012
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15 | FERMT3, LAD3
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| Loss of kindlin-3 alters the threshold for NK cell activation in human leukocyte adhesion deficiency-III.
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| Gruda R, Brown AC, Grabovsky V, Mizrahi S, Gur C, Feigelson SW, Achdout H, Bar-On Y, Alon R, Aker M, Davis DM, Mandelboim O.
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| Blood 120(19):3915-24. doi: 10.1182/blood-2012-02-410795. Epub 2012 Sep 14.
2012
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16 | FERMT3, LAD3
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| Novel aspects of Kindlin-3 function in humans based on a new case of leukocyte adhesion deficiency III.
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| Meller J, Malinin NL, Panigrahi S, Kerr BA, Patil A, Ma Y, Venkateswaran L, Rogozin IB, Mohandas N, Ehlayel MS, Podrez EA, Chinen J, Byzova TV.
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| J Thromb Haemost 10(7):1397-408. doi: 10.1111/j.1538-7836.2012.04768.x.
2012
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17 | FERMT3, RACK1
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| Kindlin-3 mediates integrin αLβ2 outside-in signaling, and it interacts with scaffold protein receptor for activated-C kinase 1 (RACK1).
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| Feng C, Li YF, Yau YH, Lee HS, Tang XY, Xue ZH, Zhou YC, Lim WM, Cornvik TC, Ruedl C, Shochat SG, Tan SM.
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| J Biol Chem 287(14):10714-26. doi: 10.1074/jbc.M111.299594. Epub 2012 Feb 10. 2012
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18 | FERMT3
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| Biophysical analysis of Kindlin-3 reveals an elongated conformation and maps integrin binding to the membrane-distal β-subunit NPXY motif.
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| Yates LA, Füzéry AK, Bonet R, Campbell ID, Gilbert RJ.
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| J Biol Chem 287(45):37715-31. doi: 10.1074/jbc.M112.415208. Epub 2012 Sep 18.
2012
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19 | FERMT3
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| Kindlin-3-mediated signaling from multiple integrin classes is required for osteoclast-mediated bone resorption.
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| Schmidt S, Nakchbandi I, Ruppert R, Kawelke N, Hess MW, Pfaller K, Jurdic P, Fässler R, Moser M.
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| J Cell Biol 192(5):883-97. Epub 2011 Feb 28.
2011
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20 | FERMT3, ITGB2, LAD3
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| Kindlin-3 is required for the stabilization of TCR-stimulated LFA-1:ICAM-1 bonds critical for lymphocyte arrest and spreading on dendritic cells.
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| Feigelson SW, Grabovsky V, Manevich-Mendelson E, Pasvolsky R, Shulman Z, Shinder V, Klein E, Etzioni A, Aker M, Alon R.
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| Blood 117(26):7042-52. Epub 2011 May 2.
2011
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21 | FERMT3
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| The integrin co-activator Kindlin-3 is expressed and functional in a non-hematopoietic cell, the endothelial cell.
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| Bialkowska K, Ma YQ, Bledzka K, Sossey-Alaoui K, Izem L, Zhang X, Malinin N, Qin J, Byzova T, Plow EF.
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| J Biol Chem 285(24):18640-9. Epub 2010 Apr 8.
2010
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22 | FERMT3, LAD3
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| Two mutations in the KINDLIN3 gene of a new leukocyte adhesion deficiency III patient reveal distinct effects on leukocyte function in vitro.
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| McDowall A, Svensson L, Stanley P, Patzak I, Chakravarty P, Howarth K, Sabnis H, Briones M, Hogg N.
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| Blood 115(23):4834-42. Epub 2010 Mar 31.
2010
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23 | FERMT3, LAD3
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| Novel integrin-dependent platelet malfunction in siblings with leukocyte adhesion deficiency-III (LAD-III) caused by a point mutation in FERMT3.
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| Jurk K, Schulz AS, Kehrel BE, Räpple D, Schulze H, Möbest D, Friedrich WW, Omran H, Deak E, Henschler R, Scheele JS, Zieger B.
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| Thromb Haemost 103(5):1053-64. Epub 2010 Mar 9.
2010
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24 | FERMT1, FERMT2, FERMT3
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| The role of kindlins in cell biology and relevance to human disease.
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| Lai-Cheong JE, Parsons M, McGrath JA.
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| Int J Biochem Cell Biol 42(5):595-603. Epub 2009 Oct 23. Review.
2010
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25 | FERMT3, LAD3
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| Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells.
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| Moser M, Bauer M, Schmid S, Ruppert R, Schmidt S, Sixt M, Wang HV, Sperandio M, Fässler R.
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| Nat Med 15(3):300-5. Epub 2009 Feb 22.
2009
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26 | FERMT3, LAD3
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| Leukocyte adhesion deficiency-III is caused by mutations in KINDLIN3 affecting integrin activation.
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| Svensson L, Howarth K, McDowall A, Patzak I, Evans R, Ussar S, Moser M, Metin A, Fried M, Tomlinson I, Hogg N.
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| Nat Med 15(3):306-12. Epub 2009 Feb 22.
2009
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27 | FERMT3, LAD3
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| A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans.
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| Malinin NL, Zhang L, Choi J, Ciocea A, Razorenova O, Ma YQ, Podrez EA, Tosi M, Lennon DP, Caplan AI, Shurin SB, Plow EF, Byzova TV.
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| Nat Med 15(3):313-8. Epub 2009 Feb 22.
2009
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28 | FERMT3
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| Loss of Kindlin-3 in LAD-III eliminates LFA-1 but not VLA-4 adhesiveness developed under shear flow conditions.
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| Manevich-Mendelson E, Feigelson SW, Pasvolsky R, Aker M, Grabovsky V, Shulman Z, Kilic SS, Rosenthal-Allieri MA, Ben-Dor S, Mory A, Bernard A, Moser M, Etzioni A, Alon R.
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| Blood 114(11):2344-53. Epub 2009 Jul 17.
2009
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29 | FERMT3
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| Kindlin-3 is essential for integrin activation and platelet aggregation.
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| Moser M, Nieswandt B, Ussar S, Pozgajova M, FŠssler R.
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| Nat Med 14(3):325-30. Epub 2008 Feb 17. 2008
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30 | FERMT3
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| URP2SF, a FERM and PH domain containing protein, regulates NF-kappaB and apoptosis.
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| Wang L, Deng W, Shi T, Ma D.
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| Biochem Biophys Res Commun 368(4):899-906. Epub 2008 Feb 14. 2008
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31 | FERMT1, FERMT2, FERMT3, KDLS
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| Kindlins: essential regulators of integrin signalling and cell-matrix adhesion.
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| Larjava H, Plow EF, Wu C.
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| EMBO Rep 9(12):1203-8. Epub 2008 Nov 7. Review.
2008
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32 | FERMT3, LAD3
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| Kindlin-3: a new gene involved in the pathogenesis of LAD-III.
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| Mory A, Feigelson SW, Yarali N, Kilic SS, Bayhan GI, Gershoni-Baruch R, Etzioni A, Alon R.
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| Blood 112(6):2591. No abstract available.
2008
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33 | FERMT1, FERMT2, FERMT3
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| The Kindlins: subcellular localization and expression during murine development.
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| Ussar S, Wang HV, Linder S, Fässler R, Moser M.
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| Exp Cell Res 312(16):3142-51. Epub 2006 Jun 29.
2006
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34 | FERMT1, FERMT2, FERMT3
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| Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome.
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| Siegel DH, Ashton GH, Penagos HG, Lee JV, Feiler HS, Wilhelmsen KC, South AP, Smith FJ, Prescott AR, Wessagowit V, Oyama N, Akiyama M, Al Aboud D, Al Aboud K, Al Githami A, Al Hawsawi K, Al Ismaily A, Al-Suwaid R, Atherton DJ, Caputo R, Fine JD, Frieden IJ, Fuchs E, Haber RM, Harada T, Kitajima Y, Mallory SB, Ogawa H, Sahin S, Shimizu H, Suga Y, Tadini G, Tsuchiya K, Wiebe CB, Wojnarowska F, Zaghloul AB, Hamada T, Mallipeddi R, Eady RA, McLean WH, McGrath JA, Epstein EH.
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| Am J Hum Genet 73(1):174-87. Epub 2003 Jun 03. 2003
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35 | FERMT1, FERMT2, FERMT3
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| Identification of serum-inducible genes: different patterns of gene regulation during G0-->S and G1-->S progression. J Cell Sci. 1994 Jan;107 ( Pt 1):227-39. Erratum in: J Cell Sci. 1994 Mar;107 ( Pt 3):preceding table of contents. PMID: 8175911 [PubMed - indexed for MEDLINE] 1243: Weinstein EJ, Bourner M, Head R, Zakeri H, Bauer C, Mazzarella R. URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.
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| Wick M, Burger C, Brusselbach S, Lucibello FC, Muller R.
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| Biochim Biophys Acta 1637(3):207-16. 2003
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36 | FERMT1, FERMT2, FERMT3
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| URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.
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| Weinstein EJ, Bourner M, Head R, Zakeri H, Bauer C, Mazzarella R.
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| Biochim Biophys Acta 1637(3):207-16. 2003
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37 | FERMT3, NIBAN3
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| Proteomic analysis of the cell-surface membrane in chronic lymphocytic leukemia: identification of two novel proteins, BCNP1 and MIG2B.
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| Boyd RS, Adam PJ, Patel S, Loader JA, Berry J, Redpath NT, Poyser HR, Fletcher GC, Burgess NA, Stamps AC, Hudson L, Smith P, Griffiths M, Willis TG, Karran EL, Oscier DG, Catovsky D, Terrett JA, Dyer MJ.
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| Leukemia 17(8):1605-12. 2003
|