| 1 | FERMT2
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| Kindlin-2 in pancreatic stellate cells promotes the progression of pancreatic cancer.
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| Yoshida N, Masamune A, Hamada S, Kikuta K, Takikawa T, Motoi F, Unno M, Shimosegawa T.
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| Cancer Lett 390:103-114. doi: 10.1016/j.canlet.2017.01.008. Epub 2017 Jan 16.
2017
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| 2 | FERMT2
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| FERMT2 rs17125944 polymorphism with Alzheimer's disease risk: a replication and meta-analysis.
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| Zhang QY, Wang HF, Zheng ZJ, Kong LL, Tan MS, Tan CC, Zhang W, Wang ZX, Tan L, Yu JT, Tan L.
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| Oncotarget 7(26):39044-39050. doi: 10.18632/oncotarget.9679.
2016
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| 3 | FERMT2
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| Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population.
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| Xiao Q, Liu ZJ, Tao S, Sun YM, Jiang D, Li HL, Chen H, Liu X, Lapin B, Wang CH, Zheng SL, Xu J, Wu ZY.
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| Oncotarget 6(35):36955-64. doi: 10.18632/oncotarget.6271.
2015
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| 4 | FBLIM1, FERMT2, SRC
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| Kindlin-2 phosphorylation by Src at Y193 enhances Src activity and is involved in Migfilin recruitment to the focal adhesions.
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| Liu Z, Lu D, Wang X, Wan J, Liu C, Zhang H.
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| FEBS Lett 589(15):2001-10. doi: 10.1016/j.febslet.2015.05.038. Epub 2015 May 30.
2015
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| 5 | ACTN2, FERMT2
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| Kindlin-2 interacts with α-actinin-2 and β1 integrin to maintain the integrity of the Z-disc in cardiac muscles
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| Qi L, Yu Y, Chi X, Xu W, Lu D, Song Y, Zhang Y, Zhang H.
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| FEBS Lett. Jul 22;589(16):2155-62. doi: 10.1016/j.febslet.2015.06.022. Epub 2015 Jul 2 2015
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| 6 | FERMT2, GLI1
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| A feedback regulation between Kindlin-2 and GLI1 in prostate cancer cells.
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| Gao J, Khan AA, Shimokawa T, Zhan J, Strömblad S, Fang W, Zhang H.
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| FEBS Lett 587(6):631-8. doi: 10.1016/j.febslet.2012.12.028. Epub 2013 Jan 18.
2013
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| 7 | FBLIM1, FERMT2
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| Kindlin binds migfilin tandem LIM domains and regulates migfilin focal adhesion localization and recruitment dynamics.
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| Brahme NN, Harburger DS, Kemp-O'Brien K, Stewart R, Raghavan S, Parsons M, Calderwood DA.
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| J Biol Chem 288(49):35604-16. doi: 10.1074/jbc.M113.483016. Epub 2013 Oct 28.
2013
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| 8 | FBLIM1, FERMT2
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| Critical role of filamin-binding LIM protein 1 (FBLP-1)/migfilin in regulation of bone remodeling.
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| Xiao G, Cheng H, Cao H, Chen K, Tu Y, Yu S, Jiao H, Yang S, Im HJ, Chen D, Chen J, Wu C.
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| J Biol Chem 287(25):21450-60. doi: 10.1074/jbc.M111.331249. Epub 2012 May 3.
2012
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| 9 | FERMT2, SP1
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| Functional characterization of human Kindlin-2 core promoter identifies a key role of SP1 in Kindlin-2 transcriptional regulation.
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| Khan AA, Shimokawa T, Strömblad S, Zhang H.
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| Cell Mol Biol Lett 16(4):638-51. Epub 2011 Sep 15.
2011
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| 10 | FERMT2
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| Membrane binding of the N-terminal ubiquitin-like domain of kindlin-2 is crucial for its regulation of integrin activation.
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| Perera HD, Ma YQ, Yang J, Hirbawi J, Plow EF, Qin J.
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| Structure 19(11):1664-71.
2011
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| 11 | FERMT2
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| Mediation of Rac1 activation by kindlin-2: an essential function in osteoblast adhesion, spreading, and proliferation.
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| Jung GY, Park YJ, Han JS.
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| J Cell Biochem 112(9):2541-8. doi: 10.1002/jcb.23178.
2011
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| 12 | FERMT2
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| Kindlin-2 regulates podocyte adhesion and fibronectin matrix deposition through interactions with phosphoinositides and integrins.
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| Qu H, Tu Y, Shi X, Larjava H, Saleem MA, Shattil SJ, Fukuda K, Qin J, Kretzler M, Wu C.
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| J Cell Sci 124(Pt 6):879-91. Epub 2011 Feb 15.
2011
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| 13 | FERMT2
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| Role of kindlin-2 in fibroblast functions: implications for wound healing.
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| He Y, Esser P, Schacht V, Bruckner-Tuderman L, Has C.
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| J Invest Dermatol 131(1):245-56. Epub 2010 Sep 23.
2011
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| 14 | FERMT1, FERMT2, FERMT3
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| The role of kindlins in cell biology and relevance to human disease.
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| Lai-Cheong JE, Parsons M, McGrath JA.
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| Int J Biochem Cell Biol 42(5):595-603. Epub 2009 Oct 23. Review.
2010
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| 15 | FERMT2
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| Kindlin-2 is expressed in malignant mesothelioma and is required for tumor cell adhesion and migration.
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| An Z, Dobra K, Lock JG, Strömblad S, Hjerpe A, Zhang H.
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| Int J Cancer 127(9):1999-2008.
2010
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| 16 | FERMT1, FERMT2
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| Kindlin-1 and -2 directly bind the C-terminal region of beta integrin cytoplasmic tails and exert integrin-specific activation effects.
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| Harburger DS, Bouaouina M, Calderwood DA.
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| J Biol Chem 284(17):11485-97. Epub 2009 Feb 23.
2009
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| 17 | FERMT2
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| Kindlin-2 controls bidirectional signaling of integrins.
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| Montanez E, Ussar S, Schifferer M, Bösl M, Zent R, Moser M, Fässler R.
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| Genes Dev 22(10):1325-30.
2008
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| 18 | FERMT2
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| Kindlin-2 (Mig-2): a co-activator of beta3 integrins.
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| Ma YQ, Qin J, Wu C, Plow EF.
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| J Cell Biol 181(3):439-46.
2008
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| 19 | FERMT1, FERMT2, FERMT3, KDLS
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| Kindlins: essential regulators of integrin signalling and cell-matrix adhesion.
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| Larjava H, Plow EF, Wu C.
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| EMBO Rep 9(12):1203-8. Epub 2008 Nov 7. Review.
2008
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| 20 | FERMT2
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| Kindlin-2 is an essential component of intercalated discs and is required for vertebrate cardiac structure and function.
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| Dowling JJ, Gibbs E, Russell M, Goldman D, Minarcik J, Golden JA, Feldman EL.
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| Circ Res 102(4):423-31. Epub 2008 Jan 3.PMID: 18174465 2008
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| 21 | FERMT2
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| Kindlin-2 is required for myocyte elongation and is essential for myogenesis.
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| Dowling JJ, Vreede AP, Kim S, Golden J, Feldman EL.
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| BMC Cell Biol 9:36.PMID: 18611274 2008
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| 22 | FERMT1, FERMT2, FERMT3
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| The Kindlins: subcellular localization and expression during murine development.
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| Ussar S, Wang HV, Linder S, Fässler R, Moser M.
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| Exp Cell Res 312(16):3142-51. Epub 2006 Jun 29.
2006
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| 23 | FERMT2
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| Expression of the mitogen-inducible gene-2 (mig-2) is elevated in human uterine leiomyomas but not in leiomyosarcomas.
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| Kato K, Shiozawa T, Mitsushita J, Toda A, Horiuchi A, Nikaido T, Fujii S, Konishi I.
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| Hum Pathol 35(1):55-60. 2004
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| 24 | FERMT1, FERMT2, FERMT3
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| Loss of kindlin-1, a human homolog of the Caenorhabditis elegans actin-extracellular-matrix linker protein UNC-112, causes Kindler syndrome.
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| Siegel DH, Ashton GH, Penagos HG, Lee JV, Feiler HS, Wilhelmsen KC, South AP, Smith FJ, Prescott AR, Wessagowit V, Oyama N, Akiyama M, Al Aboud D, Al Aboud K, Al Githami A, Al Hawsawi K, Al Ismaily A, Al-Suwaid R, Atherton DJ, Caputo R, Fine JD, Frieden IJ, Fuchs E, Haber RM, Harada T, Kitajima Y, Mallory SB, Ogawa H, Sahin S, Shimizu H, Suga Y, Tadini G, Tsuchiya K, Wiebe CB, Wojnarowska F, Zaghloul AB, Hamada T, Mallipeddi R, Eady RA, McLean WH, McGrath JA, Epstein EH.
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| Am J Hum Genet 73(1):174-87. Epub 2003 Jun 03. 2003
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| 25 | FERMT1, FERMT2, FERMT3
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| Identification of serum-inducible genes: different patterns of gene regulation during G0-->S and G1-->S progression. J Cell Sci. 1994 Jan;107 ( Pt 1):227-39. Erratum in: J Cell Sci. 1994 Mar;107 ( Pt 3):preceding table of contents. PMID: 8175911 [PubMed - indexed for MEDLINE] 1243: Weinstein EJ, Bourner M, Head R, Zakeri H, Bauer C, Mazzarella R. URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.
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| Wick M, Burger C, Brusselbach S, Lucibello FC, Muller R.
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| Biochim Biophys Acta 1637(3):207-16. 2003
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| 26 | FERMT1, FERMT2, FERMT3
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| URP1: a member of a novel family of PH and FERM domain-containing membrane-associated proteins is significantly over-expressed in lung and colon carcinomas.
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| Weinstein EJ, Bourner M, Head R, Zakeri H, Bauer C, Mazzarella R.
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| Biochim Biophys Acta 1637(3):207-16. 2003
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