Citations for
1CYP11A1, FDX1, JUN
Transcription factors SF1 and cJUN cooperate to activate the Fdx1 promoter in MA-10 Leydig cells.
Roumaud P, Rwigemera A, Martin LJ.
J Steroid Biochem Mol Biol 171:121-132. doi: 10.1016/j.jsbmb.2017.03.003. Epub 2017 Mar 6. 2017
2FDX1, FDX1L
Human Mitochondrial Ferredoxin 1 (FDX1) and Ferredoxin 2 (FDX2) Both Bind Cysteine Desulfurase and Donate Electrons for Iron-Sulfur Cluster Biosynthesis.
Cai K, Tonelli M, Frederick RO, Markley JL.
Biochemistry 56(3):487-499. doi: 10.1021/acs.biochem.6b00447. Epub 2017 Jan 11. 2017
3CYP11A1, FDX1
Active Site Structures of CYP11A1 in the Presence of Its Physiological Substrates and Alterations upon Binding of Adrenodoxin.
Zhu Q, Mak PJ, Tuckey RC, Kincaid JR.
Biochemistry 56(43):5786-5797. doi: 10.1021/acs.biochem.7b00766. Epub 2017 Oct 20. 2017
4FDX1, FDX1L
Mapping cellular Fe-S cluster uptake and exchange reactions - divergent pathways for iron-sulfur cluster delivery to human ferredoxins.
Fidai I, Wachnowsky C, Cowan JA.
Metallomics 8(12):1283-1293. 2016
5CYP27B1, FDX1, FDXR
Vitamin D-Dependent Rickets Type 1 Caused by Mutations in CYP27B1 Affecting Protein Interactions With Adrenodoxin.
Zalewski A, Ma NS, Legeza B, Renthal N, Flück CE, Pandey AV.
J Clin Endocrinol Metab 101(9):3409-18. doi: 10.1210/jc.2016-2124. Epub 2016 Jul 11. 2016
6FDX1, TNFSF13
Genetic polymorphisms in TNFSF13 and FDX1 are associated with IgA nephropathy in the Han Chinese population.
Niu D, Gao Y, Xie L, Sun J, Lu W, Jin G, Hao Y, Zhang Y, Yin A, Geng Y, Zhang W, Chen C, Li S.
Hum Immunol 76(11):831-5. doi: 10.1016/j.humimm.2015.09.044. Epub 2015 Oct 21. 2015
7FDX1, NR5A1
Transcriptional regulation of human ferredoxin 1 in ovarian granulosa cells.
Imamichi Y, Mizutani T, Ju Y, Matsumura T, Kawabe S, Kanno M, Yazawa T, Miyamoto K.
Mol Cell Endocrinol 370(1-2):1-10. doi: 10.1016/j.mce.2013.02.012. Epub 2013 Feb 19. 2013
8FDX1, FDX1L
Human ferredoxin-2 displays a unique conformational change.
Qi W, Li J, Cowan JA.
Dalton Trans 42(9):3088-91. doi: 10.1039/c2dt32018e. Epub 2012 Dec 3. 2013
9FDX1, FDX1L, FDXR
Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis.
Shi Y, Ghosh M, Kovtunovych G, Crooks DR, Rouault TA.
Biochim Biophys Acta 1823(2):484-92. doi: 10.1016/j.bbamcr.2011.11.002. Epub 2011 Nov 10. 2012
10CYP11A1, FDX1
Structural basis for pregnenolone biosynthesis by the mitochondrial monooxygenase system.
Strushkevich N, MacKenzie F, Cherkesova T, Grabovec I, Usanov S, Park HW.
Proc Natl Acad Sci U S A 108(25):10139-43. doi: 10.1073/pnas.1019441108. Epub 2011 Jun 2. Erratum in: Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):15535 2011
11FDX1, FDX1L
Humans possess two mitochondrial ferredoxins, Fdx1 and Fdx2, with distinct roles in steroidogenesis, heme, and Fe/S cluster biosynthesis.
Sheftel AD, Stehling O, Pierik AJ, Elsässer HP, Mühlenhoff U, Webert H, Hobler A, Hannemann F, Bernhardt R, Lill R.
Proc Natl Acad Sci U S A 107(26):11775-80. Epub 2010 Jun 14.PMID: 20547883 2010
12FDX1
Adrenodoxin supports reactions catalyzed by microsomal steroidogenic cytochrome P450s.
Pechurskaya TA, Harnastai IN, Grabovec IP, Gilep AA, Usanov SA.
Biochem Biophys Res Commun 353(3):598-604. Epub 2006 Dec 15.PMID: 17188650 2007
13FDX1
The structure of the 2[4Fe-4S] ferredoxin from Pseudomonas aeruginosa at 1.32-A resolution: comparison with other high-resolution structures of ferredoxins and contributing structural features to reduction potential values.
Giastas P, Pinotsis N, Efthymiou G, Wilmanns M, Kyritsis P, Moulis JM, Mavridis IM.
J Biol Inorg Chem 11(4):445-58. Epub 2006 Apr 5.PMID: 16596388 2006
14FDX1
Adrenodoxin (Adx) and CYP11A1 (P450scc) induce apoptosis by the generation of reactive oxygen species in mitochondria.
Derouet-Humbert E, Roemer K, Bureik M.
Biol Chem 386(5):453-61. 2005
15FDX1
Comparison of functional domains in vertebrate-type ferredoxins.
Kostic M, Pochapsky SS, Obenauer J, Mo H, Pagani GM, Pejchal R, Pochapsky TC.
Biochemistry 41(19):5978-89. 2002
16ST3, APOC3, CASP1, FDX1
A yeast artificial chromosome contig and NotI restriction map that spans the tumor suppressor gene(s) locus, 11q22.2-q23.3.
Arai Y, et al.
Genomics 35 : 196-206. 1996
17ACAT1, ATM, CRYAB, FDX1, FGF3, GRIA4, NCAM1, D11S1818, D11S1897, D11S1960, D11S2
Generation of a panel of radiation-reduced hybrids containing human 11q22-23 fragments bearing a HPRT selective marker : identification of hybrids carrying various subregions around the ataxia-telangiectasia locus.
Ejima Y, et al.
Somat Cell Mol Genet 22 : 499-509. 1996
18CYP11A1, CYP17A1, FDX1, FDXR
Regional mapping of genes encoding human steroidogenic enzymes : P450scc to 15q23-q24, adrenodoxin to 11q22; adrenodoxin reductase to 17q24-q25; and P450c17 to 10q24-q25.
Sparkes RS, et al.
DNA Cell Biol 10 : 359-365. 1991
19FDX1, FDXP1, FDXP2
Structure, sequence, chromosomal location, and evolution of the human ferredoxin gene family.
Chang CY, et al.
DNA Cell Biol 9(3):205-12. 1990
20FDX1, FDXP1
Assignment of the functional gene for human adrenodoxin to chromosome 11q13-qter and adrenodoxin pseudogenes to chromosome 20cen-q13.1.
Morel Y, et al.
Hum Genet 43(1):52-9. 1988
21FDX1
Two highly homologous genes for adrenodoxin lie on human chromosomes 11 and 20.
Morel Y, et al.
Am J Hum Genet 41 : A178. 1987