Citations for
1ANPEP, FCER1A
CD13/aminopeptidase N is a negative regulator of mast cell activation.
Zotz JS, Wölbing F, Lassnig C, Kauffmann M, Schulte U, Kolb A, Whitelaw B, Müller M, Biedermann T, Huber M.
FASEB J 30(6):2225-35. doi: 10.1096/fj.201600278. Epub 2016 Mar 2. 2016
2FCER1A, GATA1, GATA2, MS4A2, SPI1
Critical Roles for PU.1, GATA1, and GATA2 in the expression of human FcεRI on mast cells: PU.1 and GATA1 transactivate FCER1A, and GATA2 transactivates FCER1A and MS4A2.
Inage E, Kasakura K, Yashiro T, Suzuki R, Baba Y, Nakano N, Hara M, Tanabe A, Oboki K, Matsumoto K, Saito H, Niyonsaba F, Ohtsuka Y, Ogawa H, Okumura K, Shimizu T, Nishiyama C.
J Immunol 192(8):3936-46. doi: 10.4049/jimmunol.1302366. Epub 2014 Mar 17. 2014
3DOCK5, FCER1A
DOCK5 functions as a key signaling adaptor that links FcεRI signals to microtubule dynamics during mast cell degranulation.
Ogawa K, Tanaka Y, Uruno T, Duan X, Harada Y, Sanematsu F, Yamamura K, Terasawa M, Nishikimi A, Côté JF, Fukui Y.
J Exp Med 211(7):1407-19. doi: 10.1084/jem.20131926. 2014
4FCER1A, INPP5D, UBASH3B
Once phosphorylated, tyrosines in carboxyl terminus of protein-tyrosine kinase Syk interact with signaling proteins, including TULA-2, a negative regulator of mast cell degranulation.
de Castro RO, Zhang J, Groves JR, Barbu EA, Siraganian RP.
J Biol Chem 287(11):8194-204. doi: 10.1074/jbc.M111.326850. Epub 2012 Jan 20. 2012
5FCER1A
High-affinity IgE receptors on dendritic cells exacerbate Th2-dependent inflammation.
Sallmann E, Reininger B, Brandt S, Duschek N, Hoflehner E, Garner-Spitzer E, Platzer B, Dehlink E, Hammer M, Holcmann M, Oettgen HC, Wiedermann U, Sibilia M, Fiebiger E, Rot A, Maurer D.
J Immunol 187(1):164-71. Epub 2011 May 27. 2011
6FCER1A
IgE-dependent and IgE-independent stimulation of human basophils increases the presence of immature FcεRIα by reversing degradative pathways.
Zaidi AK, MacGlashan D Jr.
Int Arch Allergy Immunol 154(1):15-24. Epub 2010 Jul 24. 2011
7FCER1A
Counterregulation between the FcepsilonRI pathway and antiviral responses in human plasmacytoid dendritic cells.
Gill MA, Bajwa G, George TA, Dong CC, Dougherty II, Jiang N, Gan VN, Gruchalla RS.
J Immunol 184(11):5999-6006. Epub 2010 Apr 21. 2010
8FCER1A
The high affinity IgE receptor Fc epsilonRI is expressed by human intestinal epithelial cells.
Untersmayr E, Bises G, Starkl P, Bevins CL, Scheiner O, Boltz-Nitulescu G, Wrba F, Jensen-Jarolim E.
PLoS One 5(2):e9023. 2010
9FCER1A, MS4A2
FcepsilonRI beta-chain ITAM amplifies PI3K-signaling to ensure synergistic degranulation response via FcepsilonRI and adenosine receptors.
Nunomura S, Gon Y, Yoshimaru T, Kashiwakura J, Kawakami T, Ra C.
Eur J Immunol 40(4):1205-17. doi: 10.1002/eji.200939651. 2010
10FCER1A, RHOH
RhoH plays critical roles in Fc epsilon RI-dependent signal transduction in mast cells.
Oda H, Fujimoto M, Patrick MS, Chida D, Sato Y, Azuma Y, Aoki H, Abe T, Suzuki H, Shirai M.
J Immunol 182(2):957-62. 2009
11FCER1A, PTPRE
Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses.
Akimoto M, Mishra K, Lim KT, Tani N, Hisanaga SI, Katagiri T, Elson A, Mizuno K, Yakura H.
Scand J Immunol 69(5):401-11. Epub 2008 Feb 6. 2009
12FCER1A
FCER1A gene proximal promoter polymorphisms in Caucasians and East Asians.
Potaczek DP, Sanak M, Nishiyama C, Okumura K, Ogawa H, Szczeklik A.
Int J Immunogenet 35(4-5):339-40. 2008
13FCER1A
Role of the extracellular domain of Fc epsilon RI alpha in intracellular processing and surface expression of the high affinity receptor for IgE Fc epsilon RI.
Hartman ML, Lin SY, Jouvin MH, Kinet JP.
Mol Immunol 45(8):2307-11. Epub 2008 Jan 7. 2008
14FCER1A
Genetic polymorphisms of the novel FCERIA gene region: relation to total serum IgE levels.
Potaczek DP, Sanak M, Mastalerz L, Milewski M, Gawlewicz-Mroczka A, Szczeklik A.
Ann Allergy Asthma Immunol 98(5):500-1. No abstract available. 2007
15FCER1A, MS4A2
Additive association between FCER1A and FCER1B genetic polymorphisms and total serum IgE levels.
Potaczek DP, Sanak M, Szczeklik A.
Allergy 62(9):1095-6. No abstract available. 2007
16FCER1A
Transport of the IgE receptor alpha-chain is controlled by a multicomponent intracellular retention signal.
Cauvi DM, Tian X, von Loehneysen K, Robertson MW.
J Biol Chem 281(15):10448-60. Epub 2006 Feb 3. 2006
17FCER1A
p28, a novel IgE receptor-associated protein, is a sensor of receptor occupation by its ligand in mast cells.
Charles N, Monteiro RC, Benhamou M.
J Biol Chem 279(13):12312-8. Epub 2004 Jan 8. 2004
18GSD3, CDC42, MSUD2, FCER1A, GNAI3, GUCA2A, ITPKB, MATN1, MCL1, NGF, PRDX1, PTPN7, S100A10
A comprehensive view of human chromosome 1.
White PS, Sulman EP, Porter CJ, Matise TC.
Genome Res 9(10):978-88 1999
19FCER1A, FCER1G, FCER2, FCGR1A, FCGR1B, FCGR1C, FCGR2A, FCGR2B, FCGR2C, FCGR3A, FCGR3B, FCGRT, MS4A1
Structural bases of Fc gamma R functions.
Daeron M.
Int Rev Immunol 16(1-2):1-27. Review 1997
20FCER1A
Characterization of the gene for the human high affinity IgE receptor (Fc epsilon RI) alpha-chain.
Pang J, et al.
J Immunol 151 : 6166-6174. 1993
21FCER1A
The gene for the human mast cell high-affinity IgE receptor alpha chain : chromosomal localization to 1q21-q23 and RFLP analysis.
Tepler I, et al.
Am J Hum Genet 45 : 761-765. 1989