Citations for
1FBXW8
Assessment of a FBXW8 frameshift mutation, c.1312_1313delGT, in breast cancer patients and controls from Central Europe.
Wang J, Bogdanova N, Schürmann P, Park-Simon TW, Geffers R, Dörk T.
Cancer Genet 220:38-43. doi: 10.1016/j.cancergen.2017.11.006. Epub 2017 Nov 28. 2018
2FBXW8, MRFAP1
FBXW8-dependent degradation of MRFAP1 in anaphase controls mitotic cell death.
Li DZ, Liu SF, Zhu L, Wang YX, Chen YX, Liu J, Hu G, Yu X, Li J, Zhang J, Wu ZX, Lu H, Liu W, Liu B.
Oncotarget 8(57):97178-97186. doi: 10.18632/oncotarget.21843. eCollection 2017 Nov 14. 2017
3ATXN2, FBXW8, PRKN
Both ubiquitin ligases FBXW8 and PARK2 are sequestrated into insolubility by ATXN2 PolyQ expansions, but only FBXW8 expression is dysregulated.
Halbach MV, Stehning T, Damrath E, Jendrach M, Şen NE, Başak AN, Auburger G.
PLoS One 10(3):e0121089. doi: 10.1371/journal.pone.0121089. eCollection 2015. 2015
4FBXW8, MAP4K1
The CUL7/F-box and WD repeat domain containing 8 (CUL7/Fbxw8) ubiquitin ligase promotes degradation of hematopoietic progenitor kinase 1.
Wang H, Chen Y, Lin P, Li L, Zhou G, Liu G, Logsdon C, Jin J, Abbruzzese JL, Tan TH, Wang H.
J Biol Chem 289(7):4009-17. doi: 10.1074/jbc.M113.520106. Epub 2013 Dec 20. 2014
5CRTC2, FBXW8, IRS1
mTOR complex 2 regulates proper turnover of insulin receptor substrate-1 via the ubiquitin ligase subunit Fbw8.
Kim SJ, DeStefano MA, Oh WJ, Wu CC, Vega-Cotto NM, Finlan M, Liu D, Su B, Jacinto E.
Mol Cell 48(6):875-87. doi: 10.1016/j.molcel.2012.09.029. Epub 2012 Nov 8. 2012
6FBXW8, TBC1D3
Ubiquitination and degradation of the hominoid-specific oncoprotein TBC1D3 is mediated by CUL7 E3 ligase.
Kong C, Samovski D, Srikanth P, Wainszelbaum MJ, Charron AJ, Liu J, Lange JJ, Chen PI, Pan ZQ, Su X, Stahl PD.
PLoS One 7(9):e46485. doi: 10.1371/journal.pone.0046485. Epub 2012 Sep 27. 2012
7CUL7, FBXW8, OBSL1
An OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterning.
Litterman N, Ikeuchi Y, Gallardo G, O'Connell BC, Sowa ME, Gygi SP, Harper JW, Bonni A.
PLoS Biol 9(5):e1001060. Epub 2011 May 10. 2011
8CUL7, FBXW8, SKP1
The cullin7 E3 ubiquitin ligase: a novel player in growth control.
Sarikas A, Xu X, Field LJ, Pan ZQ.
Cell Cycle 7(20):3154-61. Epub 2008 Oct 4. Review.PMID: 18927510 2008
9FBXW8
A critical role for FBXW8 and MAPK in cyclin D1 degradation and cancer cell proliferation.
Okabe H, Lee SH, Phuchareon J, Albertson DG, McCormick F, Tetsu O.
PLoS One 1:e128.PMID: 17205132 2006
10BTRC, FBXL2, FBXO16, FBXW5, FBXL3, FBXL21, FBXL4, FBXL5, FBXL6, FBXL7, LRRC29, FBXO10, FBXO11, LMO7, FBXO21, FBXO22, FBXO24, FBXO25, FBXO3, FBXO4, FBXO5, FBXO6, FBXO7, FBXO8, FBXO9, FBXW11, SHFM3P1, FBXW8
Identification of a family of human F-box proteins.
Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M.
Curr Biol 9(20):1177-9. 1999
11CCNF, FBXL12, FBXL6, FBXO10, FBXO11, FBXO18, FBXO2, FBXO3, FBXO4, FBXO8, FBXW5, FBXW5, FBXW7, FBXW8, KDM2A, SHFM3P1, SKP1, TSPAN17
A family of mammalian F-box proteins.
Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
Curr Biol 9(20):1180-2. 1999