| 1 | FBXW5, TSC2
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| Tnfaip8 l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model.
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| Ha JY, Kim JS, Kang YH, Bok E, Kim YS, Son JH.
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| J Neurochem 129(3):527-38. doi: 10.1111/jnc.12643.
2014
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| 2 | EPS8, FBXW5
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| SCFFbxw5 mediates transient degradation of actin remodeller Eps8 to allow proper mitotic progression.
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| Werner A, Disanza A, Reifenberger N, Habeck G, Becker J, Calabrese M, Urlaub H, Lorenz H, Schulman B, Scita G, Melchior F.
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| Nat Cell Biol 15(2):179-88. doi: 10.1038/ncb2661.
2013
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| 3 | FBXW5, MYB
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| Fbxw5 suppresses nuclear c-Myb activity via DDB1-Cul4-Rbx1 ligase-mediated sumoylation.
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| Kanei-Ishii C, Nomura T, Egoh A, Ishii S.
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| Biochem Biophys Res Commun 426(1):59-64. doi: 10.1016/j.bbrc.2012.08.032.
2012
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| 4 | FBXW5, SASS6, SASS9
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| The SCF-FBXW5 E3-ubiquitin ligase is regulated by PLK4 and targets HsSAS-6 to control centrosome duplication.
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| Puklowski A, Homsi Y, Keller D, May M, Chauhan S, Kossatz U, Grünwald V, Kubicka S, Pich A, Manns MP, Hoffmann I, Gönczy P, Malek NP.
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| Nat Cell Biol 13(8):1004-9. doi: 10.1038/ncb2282. 2011
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| 5 | CDC20, FBXW5, PLK4, SASS6
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| FBXW5 controls centrosome number.
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| Pagan J, Pagano M.
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| Nat Cell Biol 13(8):888-90. doi: 10.1038/ncb2312. 2011
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| 6 | FBXW5, MAP3K7
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| An F-box protein, FBXW5, negatively regulates TAK1 MAP3K in the IL-1beta signaling pathway.
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| Minoda Y, Sakurai H, Kobayashi T, Yoshimura A, Takaesu G.
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| Biochem Biophys Res Commun 381(3):412-7. Epub 2009 Feb 20.
2009
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| 7 | CUL4A, DDB1, FBXW5, RBX1, TSC1, TSC2
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| WD40 protein FBW5 promotes ubiquitination of tumor suppressor TSC2 by DDB1-CUL4-ROC1 ligase.
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| Hu J, Zacharek S, He YJ, Lee H, Shumway S, Duronio RJ, Xiong Y.
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| Genes Dev 22(7):866-71. 2008
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| 8 | BTRC, FBXL2, FBXO16, FBXW5, FBXL3, FBXL21, FBXL4, FBXL5, FBXL6, FBXL7, LRRC29, FBXO10, FBXO11, LMO7, FBXO21, FBXO22, FBXO24, FBXO25, FBXO3, FBXO4, FBXO5, FBXO6, FBXO7, FBXO8, FBXO9, FBXW11, SHFM3P1, FBXW8
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| Identification of a family of human F-box proteins.
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| Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M.
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| Curr Biol 9(20):1177-9. 1999
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| 9 | CCNF, FBXL12, FBXL6, FBXO10, FBXO11, FBXO18, FBXO2, FBXO3, FBXO4, FBXO8, FBXW5, FBXW5, FBXW7, FBXW8, KDM2A, SHFM3P1, SKP1, TSPAN17
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| A family of mammalian F-box proteins.
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| Winston JT, Koepp DM, Zhu C, Elledge SJ, Harper JW.
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| Curr Biol 9(20):1180-2. 1999
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