| 1 | FBXW11, NDEDJ
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| De Novo Missense Variants in FBXW11 Cause Diverse Developmental Phenotypes Including Brain, Eye, and Digit Anomalies.
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| Holt RJ, Young RM, Crespo B, Ceroni F, Curry CJ, Bellacchio E, Bax DA, Ciolfi A, Simon M, Fagerberg CR, van Binsbergen E, De Luca A, Memo L, Dobyns WB, Mohammed AA, Clokie SJH, Zazo Seco C, Jiang YH, Sørensen KP, Andersen H, Sullivan J, Powis Z, Chassevent A, Smith-Hicks C, Petrovski S, Antoniadi T, Shashi V, Gelb BD, Wilson SW, Gerrelli D, Tartaglia M, Chassaing N, Calvas P, Ragge NK.
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| Am J Hum Genet 105(3):640-657. doi: 10.1016/j.ajhg.2019.07.005. Epub 2019 Aug 8.
2019
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| 2 | FBXW11
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| The ubiquitin ligase subunit β-TrCP in Sertoli cells is essential for spermatogenesis in mice.
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| Morohoshi A, Nakagawa T, Nakano S, Nagasawa Y, Nakayama K.
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| Dev Biol 445(2):178-188. doi: 10.1016/j.ydbio.2018.10.023. Epub 2018 Nov 2.
2019
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| 3 | FBXW11
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| Fbxw11 promotes the proliferation of lymphocytic leukemia cells through the concomitant activation of NF-κB and β-catenin/TCF signaling pathways.
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| Wang L, Feng W, Yang X, Yang F, Wang R, Ren Q, Zhu X, Zheng G.
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| Cell Death Dis 9(4):427. doi: 10.1038/s41419-018-0440-1.
2018
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| 4 | BTRC, FBXW11, MAP3K5
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| β-TrCP-dependent degradation of ASK1 suppresses the induction of the apoptotic response by oxidative stress.
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| Cheng R, Takeda K, Naguro I, Hatta T, Iemura SI, Natsume T, Ichijo H, Hattori K.
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| Biochim Biophys Acta Gen Subj 1862(10):2271-2280. doi: 10.1016/j.bbagen.2018.07.015. Epub 2018 Jul 18.
2018
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| 5 | BTRC, DMRT1, FBXW11
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| Regulation of mitosis-meiosis transition by the ubiquitin ligase β-TrCP in male germ cells.
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| Nakagawa T, Zhang T, Kushi R, Nakano S, Endo T, Nakagawa M, Yanagihara N, Zarkower D, Nakayama K.
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| Development 144(22):4137-4147. doi: 10.1242/dev.158485. Epub 2017 Oct 5.
2017
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| 6 | CDKN2A, FBXW11
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| S6 Kinase- and β-TrCP2-Dependent Degradation of p19Arf Is Required for Cell Proliferation.
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| Nakagawa T, Araki T, Nakagawa M, Hirao A, Unno M, Nakayama K.
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| Mol Cell Biol 35(20):3517-27. doi: 10.1128/MCB.00343-15. Epub 2015 Aug 3.
2015
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| 7 | FBXW11, RAPGEF2
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| Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.
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| Kim TY, Siesser PF, Rossman KL, Goldfarb D, Mackinnon K, Yan F, Yi X, MacCoss MJ, Moon RT, Der CJ, Major MB.
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| Mol Cell Biol 35(1):167-81. doi: 10.1128/MCB.00857-14. Epub 2014 Oct 20.
2015
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| 8 | BTRC, FBXW11
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| Role of β-TrCP ubiquitin ligase receptor in UVB mediated responses in skin.
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| Bhatia N, Demmer TA, Sharma AK, Elcheva I, Spiegelman VS.
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| Arch Biochem Biophys 508(2):178-84. Epub 2010 Dec 25.
2011
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| 9 | BTRC, FBXW11
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| Specificity, location and function of βTrCP isoforms and their splice variants.
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| Putters J, Slotman JA, Gerlach JP, Strous GJ.
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| Cell Signal 23(4):641-7. Epub 2010 Dec 5.
2011
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| 10 | BTRC, FBXW11, USP47
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| The ubiquitin-specific protease USP47 is a novel beta-TRCP interactor regulating cell survival.
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| Peschiaroli A, Skaar JR, Pagano M, Melino G.
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| Oncogene 29(9):1384-93. Epub 2009 Dec 7.
2010
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| 11 | BTRC, FBXW11
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| The role of {beta}-TrCP1 and {beta}-TrCP2 in circadian rhythm generation by mediating degradation of clock protein PER2.
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| Ohsaki K, Oishi K, Kozono Y, Nakayama K, Nakayama KI, Ishida N.
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| J Biochem 144(5):609-18. Epub 2008 Sep 8.
2008
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| 12 | BTRC, FBXW11
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| Silencing of both beta-TrCP1 and HOS (beta-TrCP2) is required to suppress human immunodeficiency virus type 1 Vpu-mediated CD4 down-modulation.
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| Butticaz C, Michielin O, Wyniger J, Telenti A, Rothenberger S.
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| J Virol 81(3):1502-5. Epub 2006 Nov 22.
2007
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| 13 | DUP5Q35,FBXW11, DUP5QD
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| Holoprosencephaly and preaxial polydactyly associated with a 1.24 Mb duplication encompassing FBXW11 at 5q35.1.
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| Koolen DA, Herbergs J, Veltman JA, Pfundt R, van Bokhoven H, Stroink H, Sistermans EA, Brunner HG, Geurts van Kessel A, de Vries BB.
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| J Hum Genet 51(8):721-6. Epub 2006 Jul 25. 2006
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| 14 | BTRC, FBXW11
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| SAG/ROC-SCF beta-TrCP E3 ubiquitin ligase promotes pro-caspase-3 degradation as a mechanism of apoptosis protection.
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| Tan M, Gallegos JR, Gu Q, Huang Y, Li J, Jin Y, Lu H, Sun Y.
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| Neoplasia 8(12):1042-54.
2006
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| 15 | BTRC, FBXW11
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| Expression profiles of betaTRCP1 and betaTRCP2, and mutation analysis of betaTRCP2 in gastric cancer.
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| Saitoh T, Katoh M.
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| Int J Oncol 18(5):959-64. 2001
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| 16 | FBXW11
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| Molecular cloning and genomic structure of the betaTRCP2 gene on chromosome 5q35.1.
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| Koike J, Sagara N, Kirikoshi H, Takagi A, Miwa T, Hirai M, Katoh M.
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| Biochem Biophys Res Commun 269(1):103-9. 2000
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| 17 | BTRC, FBXL2, FBXO16, FBXW5, FBXL3, FBXL21, FBXL4, FBXL5, FBXL6, FBXL7, LRRC29, FBXO10, FBXO11, LMO7, FBXO21, FBXO22, FBXO24, FBXO25, FBXO3, FBXO4, FBXO5, FBXO6, FBXO7, FBXO8, FBXO9, FBXW11, SHFM3P1, FBXW8
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| Identification of a family of human F-box proteins.
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| Cenciarelli C, Chiaur DS, Guardavaccaro D, Parks W, Vidal M, Pagano M.
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| Curr Biol 9(20):1177-9. 1999
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| 18 | AATK, ACIN1, ACOT11, ACSBG1, ADAMTS4, ADGRV1, AKAP11, ANKLE2, ARHGAP26, ARHGEF2, ASTN2, ATP2C2, ATP9A, BICD2, BZRAP1, CAND2, CEP135, CLASP1, CLASP2, CLUAP1, CLUH, CNOT3, COBL, CPNE3, CRTC1, CRY2, CSTF2T, CUL3, CUL4B, DAAM1, DAGLA, DEPDC5, DNAJC13, DOCK10, DZIP3, FBXW11, FKBP15, G3BP2, HECTD4, HEPH, HIP1R, HIPK1, ICOSLG, KIAA0649, KIAA0652, KIF13B, KIF1C, KIF21A, L3MBTL1, LDB3, MAGI2, MAP4K4, MFAP3L, MGEA5, MRC2, MTMR4, N4BP1, NPHP4, OBSL1, PAN2, PHACTR2, PHF2, PHLDB1, PLXND1, PPFIA3, PTCD1, RAB11FIP3, RBM19, RICH2, RNF40, RNF8, ROCK2, RRP12, SAPS2, SETX, SIN3B, SLC24A1, SMCHD1, SNAP91, SOCS5, SS18L1, SWAP70, TBC1D9B, TELO2, TNRC15, TSC22D2, UBE4B, UHRF1BP1L, ULK2, ZBED4, ZC3H11A, ZNF623
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| Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.
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| Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N,Ohara O.
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| DNA Res 5(3):169-76. 1998
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