1 | FBXO43, SPGF64
|
| A homozygous loss-of-function mutation in FBXO43 causes human non-obstructive azoospermia.
|
| Wu H, Zhang X, Shen Q, Liu Y, Gao Y, Wang G, Lv M, Hua R, Xu Y, Zhou P, Wei Z, Tao F, He X, Cao Y, Liu M.
|
| Clin Genet. Jan;101(1):55-64. doi: 10.1111/cge.14069. Epub 2021 Oct 11. 2022
|
2 | FBXO43
|
| Emi2 enables centriole amplification during multiciliated cell differentiation.
|
| Kim S, Chien YH, Ryan A, Kintner C
|
| Sci Adv. Apr;8(13):eabm7538. doi: 10.1126/sciadv.abm7538. Epub 2022 Apr 1. 2022
|
3 | FBXO43, OOMD12
|
| FBXO43 variants in patients with female infertility characterized by early embryonic arrest
|
| Wang W, Wang W, Xu Y, Shi J, Fu J, Chen B, Mu J, Zhang Z, Zhao L, Lin J, Du J, Li Q, He L, Jin L, Sun X, Wang L, Sang Q.
|
| Hum Reprod. Jul 19;36(8):2392-2402. doi: 10.1093/humrep/deab131. 2021
|
4 | FBXO43, SPGF64
|
| A novel homozygous FBXO43 mutation associated with male infertility and teratozoospermia in a consanguineous Chinese family
|
| Ma Y, Xie N, Xie D, Sun L, Li S, Li P, Li Y, Li J, Dong Z, Xie X.
|
| Fertil Steril. May;111(5):909-917.e1. doi: 10.1016/j.fertnstert.2019.01.007. Epub 2019 Mar 14. 2019
|
5 | CDC20, FBXO43
|
| The zinc-binding region (ZBR) fragment of Emi2 can inhibit APC/C by targeting its association with the coactivator Cdc20 and UBE2C-mediated ubiquitylation.
|
| Shoji S, Muto Y, Ikeda M, He F, Tsuda K, Ohsawa N, Akasaka R, Terada T, Wakiyama M, Shirouzu M, Yokoyama S.
|
| FEBS Open Bio. Jul 5;4:689-703. doi: 10.1016/j.fob.2014.06.010. 2014
|
6 | FBXO43
|
| Emi2-mediated inhibition of E2-substrate ubiquitin transfer by the anaphase-promoting complex/cyclosome through a D-box-independent mechanism.
|
| Tang W, Wu JQ, Chen C, Yang CS, Guo JY, Freel CD, Kornbluth S.
|
| Mol Biol Cell. Aug 1;21(15):2589-97. doi: 10.1091/mbc.E09-08-0708. Epub 2010 Jun 9 2010
|
7 | FBXO43
|
| Emi2 inhibition of the anaphase-promoting complex/cyclosome absolutely requires Emi2 binding via the C-terminal RL tail.
|
| Ohe M, Kawamura Y, Ueno H, Inoue D, Kanemori Y, Senoo C, Isoda M, Nakajo N, Sagata N.
|
| Mol Biol Cell. Mar 15;21(6):905-13. doi: 10.1091/mbc.e09-11-0974. Epub 2010 Jan 20. 2010
|
8 | FBXO43
|
| Cdc2 and Mos regulate Emi2 stability to promote the meiosis I-meiosis II transition.
|
| Tang W, Wu JQ, Guo Y, Hansen DV, Perry JA, Freel CD, Nutt L, Jackson PK, Kornbluth S.
|
| Mol Biol Cell. Aug;19(8):3536-43. doi: 10.1091/mbc.e08-04-0417. Epub 2008 Jun 11. 2008
|
9 | FBXO43, PPP2R4, MOS
|
| Control of Emi2 activity and stability through Mos-mediated recruitment of PP2A.
|
| Wu JQ, Hansen DV, Guo Y, Wang MZ, Tang W, Freel CD, Tung JJ, Jackson PK, Kornbluth S.
|
| Proc Natl Acad Sci U S A 104(42):16564-9. Epub 2007 Sep 19. 2007
|
10 | FBXO2, FBXO17, FBXO27, FBXO6, FBXO7, FBXO8, FBXO43, FBXO44
|
| A new subfamily of structurally related human F-box proteins.
|
| Ilyin GP, Serandour AL, Pigeon C, Rialland M, Glaise D, Guguen-GuillouzoC.
|
| Gene 296(1-2):11-20. 2002
|