| 1 | FBLN5, LTBP4
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| Function of latent TGFβ binding protein 4 and fibulin 5 in elastogenesis and lung development.
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| Dabovic B, Robertson IB, Zilberberg L, Vassallo M, Davis EC, Rifkin DB.
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| J Cell Physiol 230(1):226-36. doi: 10.1002/jcp.24704. 2015
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| 2 | ARCL1A, FBLN5
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| Cutis laxa with pulmonary emphysema, conjunctivochalasis, nasolacrimal duct obstruction, abnormal hair, and a novel FBLN5 mutation.
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| Kantaputra PN, Kaewgahya M, Wiwatwongwana A, Wiwatwongwana D, Sittiwangkul R, Iamaroon A, Dejkhamron P.
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| Am J Med Genet A 164A(9):2370-7. doi: 10.1002/ajmg.a.36630. Epub 2014 Jun 24.
2014
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| 3 | FBLN5
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| Fibulin-5 null mice with decreased arterial compliance maintain normal systolic left ventricular function, but not diastolic function during maturation.
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| Le VP, Stoka KV, Yanagisawa H, Wagenseil JE.
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| Physiol Rep 2(3):e00257. doi: 10.1002/phy2.257. Print 2014.
2014
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| 4 | FBLN4, FBLN5
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| Fibulin-4 and fibulin-5 in elastogenesis and beyond: Insights from mouse and human studies.
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| Papke CL, Yanagisawa H.
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| Matrix Biol 37:142-9. doi: 10.1016/j.matbio.2014.02.004. Epub 2014 Mar 6.
2014
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| 5 | FBLN5, LTBP2
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| LTBP-2 competes with tropoelastin for binding to fibulin-5 and heparin, and is a negative modulator of elastinogenesis.
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| Sideek MA, Menz C, Parsi MK, Gibson MA.
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| Matrix Biol 34:114-23. doi: 10.1016/j.matbio.2013.10.007. Epub 2013 Oct 19.
2014
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| 6 | FBLN5, LTBP4
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| Latent TGF-β binding protein 4 promotes elastic fiber assembly by interacting with fibulin-5.
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| Noda K, Dabovic B, Takagi K, Inoue T, Horiguchi M, Hirai M, Fujikawa Y, Akama TO, Kusumoto K, Zilberberg L, Sakai LY, Koli K, Naitoh M, von Melchner H, Suzuki S, Rifkin DB, Nakamura T.
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| Proc Natl Acad Sci U S A 110(8):2852-7. doi: 10.1073/pnas.1215779110. Epub 2013 Feb 4.
2013
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| 7 | FBLN5
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| Fibulin-5 protein is reduced in the lung of patients with spontaneous pneumothorax who are under 25 years old.
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| Hirai Y, Muragaki Y, Itoh S, Oikawa K, Juri M, Kondo T, Okamura Y.
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| Ann Thorac Cardiovasc Surg 18(3):200-5.
2012
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| 8 | FBLN5
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| Overexpression of fibulin-5 in retinal pigment epithelial cells inhibits cell proliferation and migration and downregulates VEGF, CXCR4, and TGFB1 expression in cocultured choroidal endothelial cells.
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| Li F, Xu H, Zeng Y, Yin ZQ.
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| Curr Eye Res 37(6):540-8. doi: 10.3109/02713683.2012.665561. Epub 2012 Feb 28.
2012
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| 9 | FBLN5, LTBP2
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| Latent transforming growth factor-β binding protein 2 negatively regulates coalescence of oxytalan fibers induced by stretching stress.
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| Tsuruga E, Oka K, Hatakeyama Y, Isokawa K, Sawa Y.
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| Connect Tissue Res 53(6):521-7. doi: 10.3109/03008207.2012.702816. Epub 2012 Jul 24.
2012
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| 10 | FBLN5
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| Fibulin-5: two for the price of one maintaining pelvic support.
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| Northington GM.
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| J Clin Invest 121(5):1688-91. doi: 10.1172/JCI57438. Epub 2011 Apr 25.
2011
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| 11 | FBLN5
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| Extracellular matrix proteases contribute to progression of pelvic organ prolapse in mice and humans.
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| Budatha M, Roshanravan S, Zheng Q, Weislander C, Chapman SL, Davis EC, Starcher B, Word RA, Yanagisawa H.
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| J Clin Invest 121(5):2048-59. doi: 10.1172/JCI45636. Epub 2011 Apr 25.
2011
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| 12 | FBLN5
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| Fibulin-5 expression in the human placenta.
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| Gauster M, Berghold VM, Moser G, Orendi K, Siwetz M, Huppertz B.
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| Histochem Cell Biol 135(2):203-13. doi: 10.1007/s00418-011-0784-4. Epub 2011 Feb 3.
2011
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| 13 | ABCA4, ARMS2, CFH, FBLN5, PRPF31, PRPF31, RHO, RPGR, USH2A
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| Photoreceptor degeneration: genetic and mechanistic dissection of a complex trait.
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| Wright AF, Chakarova CF, Abd El-Aziz MM, Bhattacharya SS.
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| Nat Rev Genet. 11(4):273-284. 2010
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| 14 | FBLN5
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| Structural effects of fibulin 5 missense mutations associated with age-related macular degeneration and cutis laxa.
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| Jones RP, Ridley C, Jowitt TA, Wang MC, Howard M, Bobola N, Wang T, Bishop PN, Kielty CM, Baldock C, Lotery AJ, Trump D.
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| Invest Ophthalmol Vis Sci. 51(5):2356-62. 2010
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| 15 | FBLN2, FBLN5
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| Fibulin-2 and fibulin-5 cooperatively function to form the internal elastic lamina and protect from vascular injury.
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| Chapman SL, Sicot FX, Davis EC, Huang J, Sasaki T, Chu ML, Yanagisawa H.
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| Arterioscler Thromb Vasc Biol 30(1):68-74. Epub 2009 Nov 5.
2010
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| 16 | ATP6V0A2, CLAR1A, CLAR1B, CLAR2, EFEMP2, FBLN5
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| Autosomal recessive cutis laxa syndrome revisited.
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| Morava E, Guillard M, Lefeber DJ, Wevers RA.
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| Eur J Hum Genet 17(9):1099-110. Epub 2009 Apr 29. Review.PMID: 19401719 2009
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| 17 | CLAR1A, CLAR1B, EFEMP2, FBLN5
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| Lethal cutis laxa with contractural arachnodactyly, overgrowth and soft tissue bleeding due to a novel homozygous fibulin-4 gene mutation.
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| Hoyer J, Kraus C, Hammersen G, Geppert JP, Rauch A.
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| Clin Genet 76(3):276-81. Epub 2009 Aug 3.
2009
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| 18 | EFEMP2, FBLN5
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| Differential regulation of elastic fiber formation by fibulin-4 and -5.
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| Choudhury R, McGovern A, Ridley C, Cain SA, Baldwin A, Wang MC, Guo C, Mironov A Jr, Drymoussi Z, Trump D, Shuttleworth A, Baldock C, Kielty CM.
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| J Biol Chem 284(36):24553-67. Epub 2009 Jul 1.PMID: 19570982 2009
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| 19 | ELN, FBLN5
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| DANCE/fibulin-5 promotes elastic fiber formation in a tropoelastin isoform-dependent manner.
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| Nonaka R, Onoue S, Wachi H, Sato F, Urban Z, Starcher BC, Seyama Y.
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| Clin Biochem 42(7-8):713-21. Epub 2009 Jan 8.PMID: 19167375 2009
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| 20 | FBLN5
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| Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.
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| Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R.
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| Exp Biol Med (Maywood) 233(2):155-62. 2008
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| 21 | CLAR1A, CLAR1B, EFEMP2, FBLN5, LOX
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| Type II autosomal recessive cutis laxa: report of another patient and molecular studies concerning three candidate genes.
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| Scherrer DZ, Alexandrino F, Cintra ML, Sartorato EL, Steiner CE.
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| Am J Med Genet A 146A(21):2740-5.
2008
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| 22 | ELN, FBLN5
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| Characterization of the molecular interaction between tropoelastin and DANCE/fibulin-5.
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| Wachi H, Nonaka R, Sato F, Shibata-Sato K, Ishida M, Iketani S, Maeda I, Okamoto K, Urban Z, Onoue S, Seyama Y.
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| J Biochem 143(5):633-9. Epub 2008 Feb 10.PMID: 18267938 2008
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| 23 | FBLN1, FBLN5
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| Basement membrane derived fibulin-1 and fibulin-5 function as angiogenesis inhibitors and suppress tumor growth.
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| Xie L, Palmsten K, MacDonald B, Kieran MW, Potenta S, Vong S, Kalluri R.
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| Exp Biol Med (Maywood) 233(2):155-62. doi: 10.3181/0706-RM-167.
2008
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| 24 | ACE, ARMD1, ARMD2, ARMD3, ARMD7, ARMD8, ARMDA, ARMDC, ARMS2, CFH, CX3CR1, FBLN5, HTRA1, MMP9, SOD2, VEGFA
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| Progress in defining the molecular biology of age related macular degeneration.
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| Lotery A, Trump D.
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| Hum Genet 122(3-4):219-36. Epub 2007 Jul 21. No abstract available. 2007
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| 25 | ARMD3, FBLN5
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| Fibulin-5 distribution in human eyes: relevance to age-related macular degeneration.
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| Mullins RF, Olvera MA, Clark AF, Stone EM.
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| Exp Eye Res 84(2):378-80. Epub 2006 Nov 14. 2007
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| 26 | FBLN5
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| Fibulin-5/DANCE has an elastogenic organizer activity that is abrogated by proteolytic cleavage in vivo.
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| Hirai M, Ohbayashi T, Horiguchi M, Okawa K, Hagiwara A, Chien KR, Kita T, Nakamura T.
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| J Cell Biol 176(7):1061-71. Epub 2007 Mar 19.
2007
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| 27 | FBLN5
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| Effects of fibulin-5 on attachment, adhesion, and proliferation of primary human endothelial cells.
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| Preis M, Cohen T, Sarnatzki Y, Ben Yosef Y, Schneiderman J, Gluzman Z, Koren B, Lewis BS, Shaul Y, Flugelman MY.
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| Biochem Biophys Res Commun 348(3):1024-33. Epub 2006 Aug 1. 2006
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| 28 | ARMD3, CLAR1A, FBLN5
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| Reduced secretion of fibulin 5 in age-related macular degeneration and cutis laxa.
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| Lotery AJ, Baas D, Ridley C, Jones RP, Klaver CC, Stone E, Nakamura T, Luff A, Griffiths H, Wang T, Bergen AA, Trump D.
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| Hum Mutat 27(6):568-74.
2006
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| 29 | FBLN5, LOXL1
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| Elastic fiber homeostasis requires lysyl oxidase-like 1 protein.
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| Liu X, Zhao Y, Gao J, Pawlyk B, Starcher B, Spencer JA, Yanagisawa H, Zuo J, Li T.
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| Nat Genet 36(2):178-82. Epub 2004 Jan 25. 2004
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| 30 | ARMD3, FBLN5
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| Age-related macular degeneration and the extracellular matrix.
|
| Johnson LV, Anderson DH.
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| N Engl J Med 351(4):320-2. No abstract available. 2004
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| 31 | FBLN5
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| Fibulin-5 antagonizes vascular endothelial growth factor (VEGF) signaling and angiogenic sprouting by endothelial cells.
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| Albig AR, Schiemann WP.
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| DNA Cell Biol 23(6):367-79. 2004
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| 32 | FBLN5, SOD3
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| Fibulin-5 is a novel binding protein for extracellular superoxide dismutase.
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| Nguyen AD, Itoh S, Jeney V, Yanagisawa H, Fujimoto M, Ushio-Fukai M, Fukai T.
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| Circ Res 95(11):1067-74. Epub 2004 Nov 4. 2004
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| 33 | ARMD3, FBLN5
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| Missense variations in the fibulin 5 gene and age-related macular degeneration.
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| Stone EM, Braun TA, Russell SR, Kuehn MH, Lotery AJ, Moore PA, Eastman CG, Casavant TL, Sheffield VC.
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| N Engl J Med 351(4):346-53. 2004
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| 34 | FBLN2, FBLN5
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| Fibulin-2 and fibulin-5 alterations in tsk mice associated with disorganized hypodermal elastic fibers and skin tethering.
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| Lemaire R, Korn JH, Schiemann WP, Lafyatis R.
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| J Invest Dermatol 123(6):1063-9.
2004
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| 35 | CLAR1A, FBLN5
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| Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene.
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| Markova D, Zou Y, Ringpfeil F, Sasaki T, Kostka G, Timpl R, Uitto J, Chu ML.
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| Am J Hum Genet 72(4):998-1004. Epub 2003 Feb 28. 2003
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| 36 | ADCL2, FBLN5
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| Genetic heterogeneity of cutis laxa: a heterozygous tandem duplication within the fibulin-5 (FBLN5) gene.
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| Markova D, Zou Y, Ringpfeil F, Sasaki T, Kostka G, Timpl R, Uitto J, Chu ML.
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| Am J Hum Genet 72(4):998-1004. Epub 2003 Feb 28.
2003
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| 37 | FBLN5
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| Fibulin-5 is an elastin-binding protein essential for elastic fibre development in vivo.
|
| Yanagisawa H, Davis EC, Starcher BC, Ouchi T, Yanagisawa M, Richardson JA, Olson EN.
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| Nature 415(6868):168-71. 2002
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| 38 | FBLN5
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| Direct interaction of the extracellular matrix protein DANCE with apolipoprotein(a) mediated by the kringle IV-type 2 domain.
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| Kapetanopoulos A, Fresser F, Millonig G, Shaul Y, Baier G, Utermann G.
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| Mol Genet Genomics 267(4):440-6. 2002
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| 39 | CLAR1A, FBLN5
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| Homozygosity for a missense mutation in fibulin-5 (FBLN5) results in a severe form of cutis laxa.
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| Loeys B, Van Maldergem L, Mortier G, Coucke P, Gerniers S, Naeyaert JM, De Paepe A.
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| Hum Mol Genet 11(18):2113-8. 2002
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| 40 | FBLN5
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| Context-specific effects of fibulin-5 (DANCE/EVEC) on cell proliferation, motility, and invasion. Fibulin-5 is induced by transforming growth factor-beta and affects protein kinase cascades.
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| Schiemann WP, Blobe GC, Kalume DE, Pandey A, Lodish HF.
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| J Biol Chem 277(30):27367-77. Epub 2002 May 20. 2002
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| 41 | FBLN5
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| Fibulin-5/DANCE is essential for elastogenesis in vivo.
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| Nakamura T, Lozano PR, Ikeda Y, Iwanaga Y, Hinek A, Minamisawa S, Cheng CF, Kobuke K, Dalton N, Takada Y, Tashiro K, Ross Jr J, Honjo T, Chien KR.
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| Nature. 415(6868):171-5. 2002
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| 42 | FBLN5
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| EVEC, a novel epidermal growth factor-like repeat-containing protein upregulated in embryonic and diseased adult vasculature.
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| Kowal RC, Richardson JA, Miano JM, Olson EN.
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| Circ Res 84(10):1166-76 1999
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| 43 | FBLN5
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| Assignment of fibulin-5 (FBLN5) to human chromosome 14q31 by in situ hybridization and radiation hybrid mapping.
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| Kowal RC, Jolsin JM, Olson EN, Schultz RA.
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| Cytogenet Cell Genet 87(1-2):2-3. No abstract available 1999
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| 44 | FBLN5
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| DANCE, a novel secreted RGD protein expressed in developing, atherosclerotic, and balloon-injured arteries.
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| Nakamura T, Ruiz-Lozano P, Lindner V, Yabe D, Taniwaki M, Furukawa Y, Kobuke K, Tashiro K, Lu Z, Andon NL, Schaub R, Matsumori A, Sasayama S, Chien KR, Honjo T.
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| J Biol Chem 274(32):22476-83. 1999
|