| 1 | FASN, METTL3
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| METTL3 inhibits hepatic insulin sensitivity via N6-methyladenosine modification of Fasn mRNA and promoting fatty acid metabolism.
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| Xie W, Ma LL, Xu YQ, Wang BH, Li SM.
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| Biochem Biophys Res Commun 518(1):120-126. doi: 10.1016/j.bbrc.2019.08.018. Epub 2019 Aug 10.
2019
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| 2 | ERBB2, FASN
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| FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration.
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| Zhou L, Jiang S, Fu Q, Smith K, Tu K, Li H, Zhao Y.
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| Oncol Rep 35(5):2715-22. doi: 10.3892/or.2016.4627. Epub 2016 Feb 19.
2016
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| 3 | FASN
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| Global Gene Deregulations in FASN Silenced Retinoblastoma Cancer Cells: Molecular and Clinico-Pathological Correlations.
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| Sangeetha M, Deepa PR, Rishi P, Khetan V, Krishnakumar S.
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| J Cell Biochem Cell Biochem. 2015 May 8. doi: 10.1002/jcb.25217. [Epub ahead of print]
2015
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| 4 | DNM1, FASN, GABBR2, RYR3
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| De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies.
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| EuroEPINOMICS-RES Consortium.
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| Am J Hum Genet 95(4):360-70. doi: 10.1016/j.ajhg.2014.08.013. Epub 2014 Sep 25.
2014
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| 5 | FASN
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| Fatty acid synthase is required for mammary gland development and milk production during lactation.
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| Suburu J, Shi L, Wu J, Wang S, Samuel M, Thomas MJ, Kock ND, Yang G, Kridel S, Chen YQ.
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| Am J Physiol Endocrinol Metab 306(10):E1132-43. doi: 10.1152/ajpendo.00514.2013. Epub 2014 Mar 25.
2014
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| 6 | FASN
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| Cancer cell-associated fatty acid synthase activates endothelial cells and promotes angiogenesis in colorectal cancer.
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| Zaytseva YY, Elliott VA, Rychahou P, Mustain WC, Kim JT, Valentino J, Gao T, O'Connor KL, Neltner JM, Lee EY, Weiss HL, Evers BM.
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| Carcinogenesis 35(6):1341-51. doi: 10.1093/carcin/bgu042. Epub 2014 Feb 7.
2014
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| 7 | FASN, THRSP
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| Modulation of tumor fatty acids, through overexpression or loss of thyroid hormone responsive protein spot 14 is associated with altered growth and metastasis.
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| Wellberg EA, Rudolph MC, Lewis AS, Padilla-Just N, Jedlicka P, Anderson SM.
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| Breast Cancer Res 16(6):481. doi: 10.1186/s13058-014-0481-z.
2014
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| 8 | ERBB2, FASN
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| Interaction between fatty acid synthase and human epidermal growth receptor 2 (HER2) in osteosarcoma cells.
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| Long XH, Zhao K, Zhang GM, Zhou Y, Zhou RP, Liu ZL, Zhang ZH.
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| Int J Clin Exp Pathol 7(12):8777-83. eCollection 2014.
2014
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| 9 | FASN
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| Fatty acid synthase as a factor required for exercise-induced cognitive enhancement and dentate gyrus cellular proliferation.
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| Chorna NE, Santos-Soto IJ, Carballeira NM, Morales JL, de la Nuez J, Cátala-Valentin A, Chornyy AP, Vázquez-Montes A, De Ortiz SP.
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| PLoS One 8(11):e77845. doi: 10.1371/journal.pone.0077845. eCollection 2013.
2013
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| 10 | FASN, THRSP
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| Metabolic control of adult neural stem cell activity by Fasn-dependent lipogenesis.
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| Knobloch M, Braun SM, Zurkirchen L, von Schoultz C, Zamboni N, Araúzo-Bravo MJ, Kovacs WJ, Karalay O, Suter U, Machado RA, Roccio M, Lutolf MP, Semenkovich CF, Jessberger S.
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| Nature 493(7431):226-30. doi: 10.1038/nature11689. Epub 2012 Dec 2.
2013
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| 11 | FASN
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| Genome-wide Linkage and Association Analyses Implicate FASN in Predisposition to Uterine Leiomyomata.
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| Eggert SL, Huyck KL, Somasundaram P, Kavalla R, Stewart EA, Lu AT, Painter JN, Montgomery GW, Medland SE, Nyholt DR, Treloar SA, Zondervan KT, Heath AC, Madden PA, Rose L, Buring JE, Ridker PM, Chasman DI, Martin NG, Cantor RM, Morton CC.
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| Am J Hum Genet 91(4):621-8. doi: 10.1016/j.ajhg.2012.08.009.
2012
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| 12 | FASN, SREBF1
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| Reduced expression of FASN through SREBP-1 down-regulation is responsible for hypoxic cell death in HepG2 cells.
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| Jung SY, Jeon HK, Choi JS, Kim YJ.
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| J Cell Biochem 113(12):3730-9. doi: 10.1002/jcb.24247.
2012
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| 13 | FASN
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| Fatty acid synthase modulates homeostatic responses to myocardial stress.
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| Razani B, Zhang H, Schulze PC, Schilling JD, Verbsky J, Lodhi IJ, Topkara VK, Feng C, Coleman T, Kovacs A, Kelly DP, Saffitz JE, Dorn GW 2nd, Nichols CG, Semenkovich CF.
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| J Biol Chem 286(35):30949-61. doi: 10.1074/jbc.M111.230508. Epub 2011 Jul 8.
2011
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| 14 | FASN
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| Expression of fatty acid synthase in nonalcoholic fatty liver disease.
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| Dorn C, Riener MO, Kirovski G, Saugspier M, Steib K, Weiss TS, Gäbele E, Kristiansen G, Hartmann A, Hellerbrand C.
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| Int J Clin Exp Pathol 3(5):505-14.
2010
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| 15 | FASN
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| Extracellular fatty acid synthase: a possible surrogate biomarker of insulin resistance.
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| Fernandez-Real JM, Menendez JA, Moreno-Navarrete JM, Blüher M, Vazquez-Martin A, Vázquez MJ, Ortega F, Diéguez C, Frühbeck G, Ricart W, Vidal-Puig A.
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| Diabetes 59(6):1506-11. doi: 10.2337/db09-1756. Epub 2010 Mar 18.
2010
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| 16 | FASN
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| Increased expression of fatty acid synthase in human aberrant crypt foci: possible target for colorectal cancer prevention.
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| Kearney KE, Pretlow TG, Pretlow TP.
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| Int J Cancer 125(1):249-52.
2009
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| 17 | FASN
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| Fatty acid synthase: a metabolic enzyme and candidate oncogene in prostate cancer.
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| Migita T, Ruiz S, Fornari A, Fiorentino M, Priolo C, Zadra G, Inazuka F, Grisanzio C, Palescandolo E, Shin E, Fiore C, Xie W, Kung AL, Febbo PG, Subramanian A, Mucci L, Ma J, Signoretti S, Stampfer M, Hahn WC, Finn S, Loda M.
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| J Natl Cancer Inst 101(7):519-32. Epub 2009 Mar 24.
2009
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| 18 | ACACA, FASN, SIK1, SREBF1
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| Salt-inducible kinase regulates hepatic lipogenesis by controlling SREBP-1c phosphorylation.
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| Yoon YS, Seo WY, Lee MW, Kim ST, Koo SH.
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| J Biol Chem 284(16):10446-52. Epub 2009 Feb 25.PMID: 1924423 2009
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| 19 | FASN
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| Fatty acid synthase and AKT pathway signaling in a subset of papillary thyroid cancers.
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| Uddin S, Siraj AK, Al-Rasheed M, Ahmed M, Bu R, Myers JN, Al-Nuaim A, Al-Sobhi S, Al-Dayel F, Bavi P, Hussain AR, Al-Kuraya KS.
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| J Clin Endocrinol Metab 93(10):4088-97. Epub 2008 Aug 5.
2008
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| 20 | FASN
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| Fatty acid synthase gene expression in human adipose tissue: association with obesity and type 2 diabetes.
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| Berndt J, Kovacs P, Ruschke K, Klöting N, Fasshauer M, Schön MR, Körner A, Stumvoll M, Blüher M.
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| Diabetologia 50(7):1472-80. Epub 2007 May 11.
2007
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| 21 | FASN
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| The human fatty acid synthase: a new therapeutic target for coxsackievirus B3-induced diseases?
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| Rassmann A, Henke A, Jarasch N, Lottspeich F, Saluz HP, Munder T.
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| Antiviral Res 76(2):150-8. Epub 2007 Jul 16.
2007
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| 22 | DGAT2, ELOVL2, FABP4, FASN
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| ELOVL2 overexpression enhances triacylglycerol synthesis in 3T3-L1 and F442A cells.
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| Kobayashi T, Zadravec D, Jacobsson A.
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| FEBS Lett 581(17):3157-63. Epub 2007 Jun 11.
2007
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| 23 | MCAT, FASN, NDUFAB1
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| Cloning, expression, characterization, and interaction of two components of a human mitochondrial fatty acid synthase. Malonyltransferase and acyl carrier protein.
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| Zhang L, Joshi AK, Smith S.
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| J Biol Chem 278(41):40067-74. Epub 2003 Jul 25. 2003
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| 24 | FASN
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| Human fatty acid synthase: Role of interdomain in the formation of catalytically active synthase dimer.
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| Chirala SS, Jayakumar A, Gu ZW, Wakil SJ.
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| Proc Natl Acad Sci U S A 98(6):3104-8. 2001
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| 25 | FASN
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| Human fatty acid synthase mRNA : tissues distribution, genetic mapping and kinetics of decay after glucose deprivation.
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| Semenkovich CF, et al.
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| J Lipid Res 36 : 1507-1521. 1995
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| 26 | FASN
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| Human fatty acid synthase : properties and molecular cloning.
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| Jayakumar A, et al.
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| Proc Natl Acad Sci U S A 92 : 8695-8699. 1995
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| 27 | FASN
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| Isolation and chromosomal mapping of genomic clones encoding the human fatty acid synthase gene.
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| Jayakumar A, et al.
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| Genomics 23 : 420-424. 1994
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