Citations for
1APC, FAP
APC germline mutations in families with familial adenomatous polyposis.
De Queiroz Rossanese LB, De Lima Marson FA, Ribeiro JD, Coy CS, Bertuzzo CS.
Oncol Rep 30(5):2081-8. doi: 10.3892/or.2013.2681. Epub 2013 Aug 21. 2013
2APC, FAP, MAP, MUTYH
APC or MUTYH mutations account for the majority of clinically well-characterized families with FAP and AFAP phenotype and patients with more than 30 adenomas.
Filipe B, Baltazar C, Albuquerque C, Fragoso S, Lage P, Vitoriano I, Mão de Ferro S, Claro I, Rodrigues P, Fidalgo P, Chaves P, Cravo M, Nobre Leitão C.
Clin Genet 76(3):242-55. 2009
3APC, FAP,HDD
APC mutations in FAP-associated desmoid tumours are non-random but not 'just right'.
Latchford A, Volikos E, Johnson V, Rogers P, Suraweera N, Tomlinson I, Phillips R, Silver A.
Hum Mol Genet 16(1):78-82. Epub 2006 Nov 29. 2007
4APC, FAP
Genotype-phenotype correlations in 19 Dutch cases with APC gene deletions and a literature review.
Nielsen M, Bik E, Hes FJ, Breuning MH, Vasen HF, Bakker E, Tops CM, Weiss MM.
Eur J Hum Genet 15(10):1034-42. Epub 2007 Jun 13. 2007
5FAP, APC, MAP, MUTYH
Germline mutations in APC and MUTYH are responsible for the majority of families with attenuated familial adenomatous polyposis.
Nielsen M, Hes FJ, Nagengast FM, Weiss MM, Mathus-Vliegen EM, Morreau H, Breuning MH, Wijnen JT, Tops CM, Vasen HF.
Clin Genet 71(5):427-33. 2007
6MUTYH, APC, FAP, FTACC
MUTYH-associated polyposis: 70 of 71 patients with biallelic mutations present with an attenuated or atypical phenotype.
Aretz S, Uhlhaas S, Goergens H, Siberg K, Vogel M, Pagenstecher C, Mangold E, Caspari R, Propping P, Friedl W.
Int J Cancer 119(4):807-14. 2006
7MUTYH, APC, FAP, FTACC
Prevalence of MYH germline mutations in Swiss APC mutation-negative polyposis patients.
Russell AM, Zhang J, Luz J, Hutter P, Chappuis PO, Berthod CR, Maillet P, Mueller H, Heinimann K.
Int J Cancer 118(8):1937-40. 2006
8FAP, APC, HDD
Current ideas in desmoid tumours.
Sturt NJ, Clark SK.
Fam Cancer 5(3):275-85; discussion 287-8. Review. 2006
9APC,DEL5Q,FAP
Phenotypic and molecular characterisation of a de novo 5q deletion that includes the APC gene.
Ofner L, Raedle J, Windpassinger C, Schwarzbraun T, Kroisel PM, Wagner K, Petek E.
J Hum Genet 51(2):141-6. Epub 2005 Dec 20. 2006
10APC,DEL5Q,FAP
Large deletions of the APC gene in 15% of mutation-negative patients with classical polyposis (FAP): a Belgian study.
Michils G, Tejpar S, Thoelen R, van Cutsem E, Vermeesch JR, Fryns JP, Legius E, Matthijs G.
Hum Mutat 25(2):125-34. 2005
11FAP, HDD
Evidence for genetic predisposition to desmoid tumours in familial adenomatous polyposis independent of the germline APC mutation.
Sturt NJ, Gallagher MC, Bassett P, Philp CR, Neale KF, Tomlinson IP, Silver AR, Phillips RK.
Gut 53(12):1832-6. 2004
12HNPCC1, HNPCC2, HNPCC3, HNPCC4, FAP, MUTYH, MAP
An update on the genetics of colorectal cancer.
Kemp Z, Thirlwell C, Sieber O, Silver A, Tomlinson I.
Hum Mol Genet 13 Spec No 2:R177-85. Review. 2004
13FAP, APC
Refining the relation between 'first hits' and 'second hits' at the APC locus: the 'loose fit' model and evidence for differences in somatic mutation spectra among patients.
Crabtree M, Sieber OM, Lipton L, Hodgson SV, Lamlum H, Thomas HJ, Neale K, Phillips RK, Heinimann K, Tomlinson IP.
Oncogene 22(27):4257-65. 2003
14APC, KRAS, TP53, FAP
Mutations in APC, Kirsten-ras, and p53--alternative genetic pathways to colorectal cancer.
Smith G, Carey FA, Beattie J, Wilkie MJ, Lightfoot TJ, Coxhead J, Garner RC, Steele RJ, Wolf CR.
Proc Natl Acad Sci U S A 99(14):9433-8. 2002
15APC,DEL5Q,FAP
Whole-gene APC deletions cause classical familial adenomatous polyposis, but not attenuated polyposis or multiple colorectal adenomas.
Sieber OM, Lamlum H, Crabtree MD, Rowan AJ, Barclay E, Lipton L, Hodgson S, Thomas HJ, Neale K, Phillips RK, Farrington SM, Dunlop MG, Mueller HJ, Bisgaard ML, Bulow S, Fidalgo P, Albuquerque C, Scarano MI, Bodmer W, Tomlinson IP, Heinimann K.
Proc Natl Acad Sci U S A 99(5):2954-8. Epub 2002 Feb 26. 2002
16APC, FAP
Distinctive molecular genetic alterations in sporadic and familial adenomatous polyposis-associated pancreatoblastomas : frequent alterations in the APC/beta-catenin pathway and chromosome 11p.
Abraham SC, Wu TT, Klimstra DS, Finn LS, Lee JH, Yeo CJ, Cameron JL, Hruban RH.
Am J Pathol 159(5):1619-27. 2001
17DEL5Q,FAP
A de novo deletion of chromosome 5q causing familial adenomatous polyposis, dysmorphic features, and mild mental retardation.
Raedle J, Friedl W, Engels H, Koenig R, Trojan J, Zeuzem S.
Am J Gastroenterol 96(10):3016-20. 2001
18APC, FAP
Deletion and duplication of the adenomatous polyposis coli gene resulting from an interchromosomal insertion involving 5(q22q23.3) in the father.
Hastings RJ, Svennevik EC, Setterfield B, Wells D, Delhanty JD, Mackinnon H.
J Med Genet 37(2):141-5. No abstract available. 2000
19APC, FAP
Genomic rearrangements of the APC tumor-suppressor gene in familial adenomatous polyposis
Su LK, Steinbach G, Sawyer JC, Hindi M, Ward PA, Lynch PM.
Hum Genet 106:101-107 2000
20APC, FAP
APC mutations are sufficient for the growth of early colorectal adenomas.
Lamlum H, Papadopoulou A, Ilyas M, Rowan A, Gillet C, Hanby A, Talbot I, Bodmer W, Tomlinson I.
Proc Natl Acad Sci U S A 97(5):2225-8. 2000
21APC, FAP
APC mutations in sporadic colorectal tumors: A mutational hotspot and interdependence of the two hits.
Rowan AJ, Lamlum H, Ilyas M, Wheeler J, Straub J, Papadopoulou A, Bicknell D, Bodmer WF, Tomlinson IP.
Proc Natl Acad Sci U S A 97(7):3352-7. 2000
22APC, FAP
Inactivation of germline mutant APC alleles by attenuated somatic mutations: a molecular genetic mechanism for attenuated familial adenomatous polyposis.
Su LK, Barnes CJ, Yao W, Qi Y, Lynch PM, Steinbach G.
Am J Hum Genet 67(3):582-90. 2000
23APC, FAP
Molecular analysis of the APC gene in 205 families : extended genotype-phenotype correlations in FAP and evidence for the role of APC amino acid changes in colorectal cancer predisposition.
Wallis YL, Morton DG, McKeown CM, Macdonald F.
J Med Genet 36 : 14-20. 1999
24APC, FAP
Familial adenomatous polyposis associated with multiple adrenal adenomas in a patient with a rare 3' APC mutation.
Kartheuser A, Walon C, West S, Breukel C, Detry R, Gribomont AC, Hamzehloei T, Hoang P, Maiter D, Pringot J, Rahier J, Khan PM, Curtis A, Burn J, Fodde R, Verellen-Dumoulin C.
J Med Genet 36 : 65-67. 1999
25APC, CTNNB1, FAP
Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas.
Mann B, et al.
Proc Natl Acad Sci U S A 96 : 1603-1608. 1999
26APC, CTNNB1, FAP
Germline mutations are frequent in the APC gene but absent in the beta-catenin gene in familial adenomatous polyposis patients.
Cao X, et al.
Genes Chromosomes Cancer 25(4):396-8. 1999
27APC, FAP
Dominant negative effect of the APC1309 mutation: a possible explanation for genotype-phenotype correlations in familial adenomatous polyposis.
Dihlmann S, et al.
Cancer Res 59(8):1857-60. 1999
28APC, FAP
The type of somatic mutation at APC in familial adenomatous polyposis is determined by the site of the germline mutation: a new facet to Knudson's 'two-hit' hypothesis.
Lamlum H, et al.
Nat Med 5(9):1071-5 1999
29APC, FAP
Inherited colorectal polyposis and cancer risk of the APC I1307K polymorphism.
Gryfe R, et al.
Am J Hum Genet 64(2):378-84 1999
30APC, CTNNB1, FAP
Frequent mutation of beta-catenin and APC genes in primary colorectal tumors from patients with hereditary nonpolyposis colorectal cancer.
Miyaki M, Iijima T, Kimura J, Yasuno M, Mori T, Hayashi Y, Koike M, Shitara N, Iwama T, Kuroki T.
Cancer Res 59(18):4506-9 1999
31APC, FAP
Genotype-phenotype correlations in attenuated adenomatous polyposis coli.
Soravia C, et al.
Am J Hum Genet 62 : 1290-1301. 1998
32APC, FAP
The APC variants I1307K and E1317Q are associated with colorectal tumors, but not always with a family history.
Frayling IM, et al.
Proc Natl Acad Sci U S A 95 : 10722-10727. 1998
33APC, BRCA1, DPP4, MLH1, MSH2, MSH6, NF1, PMS2, RB1, TP53, VHL, WT1, FAP
Tumour suppressor gene mutations in humans and mice : parallels and contrasts.
Hooper ML.
EMBO J 17(23):6783-9. 1998
34APC, FAP
Alleles of APC modulate the frequency and classes of mutations that lead to colon polyps.
Spirio LN, et al.
Nat Genet 20 : 385-388. 1998
35APC, KRAS1P, FAP
[Analysis of genetic disorders of cancer of the rectum : differences in relation to cancer of the colon].
Rebischung C, Laurent-Puig P, Gerard JP, Thomas G, Hamelin R.
Gastroenterol Clin Biol 22 : 679-687. 1998
36APC, FAP
Molecular analysis of the APC gene in 105 Dutch kindreds with familial adenomatous polyposis : 67 germline mutations identified by DGGE, PTT, and Southern analysis.
Van der Luijt RB, et al.
Hum Mutat 9 : 7-16. 1997
37APC, CTNNB1, LEF1, FAP
Activation of beta-catenin-Tcf signaling in colon cancer by mutations in beta-catenin or APC.
Morin PJ, et al.
Science 275 : 1787-1790. 1997
38APC, CTNNB1, TCF7L2, FAP
Constitutive transcriptional activation by a beta-catenin-Tcf complex in APC-/- colon carcinoma.
Korinek V, et al.
Science 275 : 1784-1787. 1997
39APC, FAP
Characterization of 19 novel and six recurring APC mutations in Italian adenomatous polyposis patients, using two different mutation detection techniques.
Gismondi V, et al.
Hum Mutat 9 : 370-373. 1997
40APC, FAP
Familial colorectal cancer in Ashkenazim due to a hypermutable tract in APC.
Laken SJ, Petersen GM, Gruber SB, Oddoux C, Ostrer H, Giardiello FM, Hamilton SR, Hampel H, Markowitz A, Klimstra D, Jhanwar S, Winawer S, Offit K, Luce MC, Kinzler KW, Vogelstein B.
Nat Genet 17(1):79-83. 1997
41APC, FAP
Novel germline mutations in the APC gene and their phenotypic spectrum in familial adenomatous polyposis kindreds.
Walon C, Kartheuser A, Michils G, Smaers M, Lannoy N, Ngounou P, Mertens G, Verellen-Dumoulin C.
Hum Genet 100(5-6):601-5. 1997
42APC, FAP
Familial adenomatous polyposis : a submicroscopic deletion at the APC locus in a family with mentally normal patients.
Mandl M, et al.
Hum Genet 97 : 204-208. 1996
43APC, FAP
Attenuated familial adenomatous polyposis due to a mutation in the 3' part of the APC gene. A clue for understanding the function of the APC protein.
Friedl W, et al.
Hum Genet 97 : 579-584. 1996
44APC, TP53, FAP
Database of mutations in the p53 and APC tumor suppressor genes designedto facilitate molecular epidemiological analyses.
de Vries EMG, et al.
Hum Mutat 7 : 202-213. 1996
45APC, FAP
Correlation between the development of extracolonic manifestations in FAP patients and mutations beyond codon 1403 in the APC gene.
Dobbie Z, et al.
J Med Genet 33 : 274-280. 1996
46APC, FAP
Identification of a novel single base insertion in the adenomatous polyposis coli gene.
Kotze MJ, et al.
Hum Mutat 7 : 68-69. 1996
47APC, FAP
APC mutations in colorectal tumors with mismatch repair deficiency.
Huang J, et al.
Proc Natl Acad Sci U S A 93 : 9049-9054. 1996
48APC, FAP
Germline mutations in the 3' part of APC exon 15 do not result in truncated proteins and are associated with attenuated adenomatous polyposis coli.
Van der Luijt RB, et al.
Hum Genet 98 : 727-734. 1996
49APC, FAP
Three novel APC gene mutations in Portuguese FAP kindreds.
Marshall B, et al.
Hum Mutat 8 : 395. 1996
50APC, FAP
Mutation detection in exons 1-14 of the adenomatous polyposis coli gene : identification of an alternatively spliced transcript.
Hamzehloei T, et al.
Mol Cell Probes 10 : 379-385. 1996
51APC, TSG5A, FAP
APC gene mutations and allelic losses in sporadic ampullary tumours : evidence of genetic difference from tumours associated with familial adenomatous polyposis.
Achille A, et al.
Int J Cancer 68 : 305-312. 1996
52APC, CHRPE, FAP
Congenital hypertrophy of the retinal pigment epithelium in familial adenomatous polyposis. Novel criteria of assessment and correlations with constitutional adenomatous polyposis coli gene mutations.
Valanzano R, Cama A, Volpe R, Curia MC, Mencucci R, Palmirotta R, Battista P, Ficari F, Mariani-Costantini R, Tonelli F.
Cancer 78(11):2400-10.PMID: 8941012 [PubMed - indexed for MEDLINE] 1996
53APC, FAP
Multiplex PCR analysis and genotype-phenotype correlations of frequent APC mutations.
Cama A, et al.
Hum Mutat 5 : 144-152. 1995
54APC, CHRPE, FAP
Severe Gardner syndrome in families with mutations restricted to a specific region of the APC gene.
Davies DR, et al.
Am J Hum Genet 57 : 1151-1158. 1995
55APC, FAP
Attenuated familial adenomatous polyposis (AFAP).
Lynch HT, et al.
Cancer 76 : 2427-2433. 1995
56APC, FAP
Molecular genetic analysis of exons 1 to 6 of the APC gene in non-polyposis familial colorectal cancer.
Joyce JA, et al.
Clin Genet 48 : 299-303. 1995
57APC, FAP
Familial adenomatous polyposis : desmoid tumours and lack of ophthalmic lesions (CHRPE) associated with APC mutations beyond codon 1444.
Caspari R, et al.
Hum Mol Genet 4 : 337-340. 1995
58APC, MLH1, MHS2, PMS2, FAP
The molecular basis of Turcot's syndrome.
Hamilton SR, et al.
N Engl J Med 332 : 839-847. 1995
59APC, FAP
Haplotype comparison in fresh mutation cases of adenomatous polyposis coli due to deletion AAAGA at codon 1309.
Delhanty JDA, et al.
Ann Hum Genet 59 : 39-42. 1995
60APC, FAP
Molecular, cytogenetic, and phenotypic studies of a constitutional reciprocal translocation t(5;10)(q22;q25) responsible for familial adenomatous polyposis in a Dutch pedigree.
Van der Luijt RB, et al.
Genes Chromosomes Cancer 13 : 192-202. 1995
61APC, FAP
Rapid detection of rare variants and common polymorphisms in the APC gene by PCR-SSCP for presymptomatic diagnosis and showing allele loss.
Gayther SA, et al.
J Med Genet 32 : 568-571. 1995
62APC, FAP
Evidence for a novel exon in the coding region of the adenomatous polyposis coli (APC) gene.
Xia L, et al.
Genomics 28 : 589-591. 1995
63APC, FAP
Exon eight APC mutations account for a disproportionate number of familial adenomatous polyposis families.
Koorey DJ, et al.
Hum Mutat 3 : 12-18. 1994
64APC, TSG5A, FAP
Mutation in a splice-donor site of the APC gene in a family with polyposis and late age of colonic cancer death.
Varesco L, et al.
Hum Genet 93 : 281-286. 1994
65APC, FAP
Frequency of common and novel inactivating APC mutations in 202 families with familial adenomatous polyposis.
Mandl M, et al.
Hum Mol Genet 3 : 181-184. 1994
66APC, FAP
Regionally clustered APC mutations are associated with a severe phenotype and occur at a high frequency in new mutation cases of adenomatous polyposis coli.
Gayther SA, et al.
Hum Mol Genet 3 : 53-56. 1994
67APC, TSG5A, FAP
Frequent polymorphism in exon 15 of the adenomatous polyposis coli gene.
Davies SM, et al.
Hum Genet 93 : 329-330. 1994
68APC, FAP
Adenomatous polyposis coli and a cytogenetic deletion of chromosome 5 resulting from a maternal intrachromosomal insertion.
Barber JCK, et al.
J Med Genet 31 : 312-316. 1994
69APC, FAP
A somatic mutation in the adenomatous polyposis coli (APC) gene in peripheral blood cells - implications for predictive diagnosis.
Mandl M, et al.
Hum Mol Genet 3 : 1009-1011. 1994
70APC, FAP, FAP
Four novel germ-line mutations in the APC gene detected by heteroduplex analysis.
Hamzehloei T, et al.
Hum Mol Genet 3 : 1023-1024. 1994
71APC, FAP
Identification of a novel germline mutation in a FAP family.
Gebert JF, et al.
Hum Mol Genet 3 : 1167-1168. 1994
72APC, FAP
Four novel mutations of the APC (adenomatous polyposis coli) gene in FAP patients.
Stella A, et al.
Hum Mol Genet 3 : 1687-1688. 1994
73APC, FAP
Eleven novel germline mutations in the adenomatous polyposis coli (APC) gene.
Paffenholz R, et al.
Hum Mol Genet 3 : 1703-1704. 1994
74APC, FAP
APC mutation associated with late onset of familial adenomatous polyposis.
Smith-Ravin J, et al.
J Med Genet 31 : 888-890. 1994
75APC, FAP
Characterization of two novel adenomatous polyposis coli (APC) gene mutations in patients with familial adenomatous polyposis (FAP).
Bapat B, et al.
Hum Mutat 4 : 253-256. 1994
76APC, FAP
Mutations of the adenomatous polyposis coli gene in the mutation cluster region : comparison of human pancreatic and colorectal cancers.
Yashima K, et al.
Int J Cancer 59 : 43-47. 1994
77APC, FAP
Mutations of the APC (adenomatous polyposis coli) gene.
Nagase H, et al.
Hum Mutat 2 : 425-434. 1993
78APC, FAP
Molecular diagnosis of familial adenomatous polyposis.
Powell SM, et al.
N Engl J Med 329 : 1982-1987. 1993
79CHRPE, APC, FAP
Restriction of ocular fundus lesions to a specific subgroup of APC mutations in adenomatous polyposis coli patients.
Olschwang S, et al.
Cell 75 : 959-968. 1993
80APC, FAP
Alleles of the APC gene : an attenuated form of familial polyposis.
Spirio L, et al.
Cell 75 : 951-957. 1993
81APC, FAP
A novel mutation of the APC (adenomatous polyposis coli) gene in a familial adenomatous polyposis (FAP) patient and presymptomatic diagnosis using PCR.
Ichii S, et al.
Hum Mol Genet 2 : 597. 1993
82APC, FAP
Presymptomatic direct detection of adenomatous polyposis coli (APC) gene mutations in familial adenomatous polyposis.
Petersen GM, et al.
Hum Genet 91 : 307-311. 1993
83APC, FAP
Identical APC exon 15 mutations result in a variable phenotype in familial adenomatous polyposis.
Paul P, et al.
Hum Mol Genet 2 : 925-931. 1993
84APC, FAP
Mutational analysis of patients with adenomatous polyposis : identical inactivating mutations in unrelated individuals.
Groden J, et al.
Am J Hum Genet 52 : 263-272. 1993
85APC, FAP
The APC (adenomatous polyposis coli) gene : a novel mutation in an FAP patient and a DdeI polymorphism in the 5' noncoding region.
Mori T, et al.
Hum Mutat 2 : 240-243. 1993
86APC, FAP
Linkage studies in Italian families with familial adenomatous polyposis.
Mareni C, et al.
Hum Genet 90 : 545-550. 1993
87APC, FAP
Disruption of the APC gene by a retrotransposal insertion of L1 sequence in a colon cancer.
Miki Y, et al.
Cancer Res 52 : 643-645. 1992
88APC, FAP
Phenotypic, cytogenetic, and molecular studies of three patients with constitutional deletions of chromosome 5 in the region of the gene for familial adenomatous polyposis.
Lindgren V, et al.
Am J Hum Genet 50 : 988-997. 1992
89APC, FAP
Germ-line mutations of the APC gene in 53 familial adenomatous polyposis patients.
Miyoshi Y, et al.
Proc Natl Acad Sci U S A 89 : 4452-4456. 1992
90APC, FAP
Familial adenomatous polyposis : identification of a new frameshift mutation of the APC gene in an Italian family.
Stella A, et al.
Biochem Biophys Res Commun 184 : 1357-1363. 1992
91APC, MCC, FAP
Evidence that the MCC-APC gene region in 5q21 is not the site for susceptibility to hereditary nonpolyposis colorectal carcinoma.
PeltomŠki P, et al.
Cancer Res 52 : 4530-4533. 1992
92APC, FAP
Linkage of a variant or attenuated form of adenomatous polyposis coli to the adenomatous polyposis coli (APC) locus.
Spirio L, et al.
Am J Hum Genet 51 : 92-100. 1992
93APC, FAP
An intrachromosomal insertion causing 5q22 deletion and familial adenomatous polyposis coli in two generations.
Cross I, et al.
J Med Genet 29 : 175-179. 1992
94APC, DIHBD, FAP
Two cases of 5q deletions in patients with familial adenomatous polyposis : possible link with Caroli's disease.
Hodgson SV, et al.
J Med Genet 30 : 369-375. 1992
95APC, FAP
Inactivation of both APC alleles in an early stage of colon adenomas in a patient with familial adenomatous polyposis (FAP).
Ichii S, et al.
Hum Mol Genet 1 : 387-390. 1992
96APC, FAP
Identification and characterization of the familial adenomatous polyposis coli gene.
Groden J, et al.
Cell 66 : 589-600. 1991
97APC, FAP
Linkage analysis in adenomatous polyposis coli: the use of four closely linked DNA probes in 20 UK families.
Cachon-Gonzalez MB, et al.
J Med Genet 28 : 681-685. 1991
98APC, D5S299, FAP
CA repeat polymorphism at the D5S299 locus linked to adenomatous polyposis coli (APC).
van Leeuwen C, et al.
Nucleic Acids Res 19 : 5805. 1991
99APC, FAP
Gardner syndrome in a boy with interstitial deletion of the long arm of chromosome 5.
Kobayashi T, et al.
Am J Med Genet 41 : 460-463. 1991
100APC, D5S71, FAP
A new deletion polymorphism at D5S71 raises the linkage information on adenomatous polyposis coli : implications for presymptomatic diagnosis.
Tops CMJ, et al.
Hum Genet 86 : 365-368. 1991
101SRP19, APC, REEP5, FAP
Identification of deletion mutations and three new genes at the familial polyposis locus.
Joslyn G, Carlson M, Thliveris A, Albertsen H, Gelbert L, Samowitz W,Groden J, Stevens J, Spirio L, Robertson M, et al.
Cell 66(3):601-13. 1991
102APC, FAP, REEP5, SLC25A46
Mutations of chromosome 5q21 genes in FAP and colorectal cancer patients.
Nishisho I, Nakamura Y, Miyoshi Y, Miki Y, Ando H, Horii A, Koyama K, Utsunomiya J, Baba S, Hedge P.
Science 253(5020):665-9. 1991
103APC, FAP
Genetic analysis of an inherited predisposition to colon cancer in a family with a variable number of adenomatous polyps.
Leppert M, et al.
N Engl J Med 322 : 904-908. 1990
104APC, FAP
A constitutional 5q23 deletion.
Rivera H, et al.
J Med Genet 27 : 267-268. 1990
105APC, FAP
Genetic linkage map of six polymorphic DNA markers around the gene for familial adenomatous polyposis on chromosome 5.
Dunlop MG, et al.
Am J Hum Genet 47 : 982-987. 1990
106APC, FAP
Deletion of chromosome 5q and familial adenomatous polyposis.
Hockey KA, Mulcahy MT, Montgomery P, Levitt S.
J Med Genet 26 : 61-68. 1989
107APC, FAP
Linkage analysis in familial adenomatous polyposis : order of C11P11 (D5S71) and pi227 (D5S37) loci at the apc gene.
Dunlop MG, Steel CM, Wyllie AH, Bird CC, Evans HJ.
Genomics 5 : 350-353. 1989
108APC, FAP
Presymptomatic diagnosis of familial adenomatous polyposis by bridging DNA markers.
Tops CMJ, et al.
Lancet II : 1361-1363. 1989
109APC, D5S120, FAP
High frequency of APC loss in sporadic colorectal carcinoma due to breaks clustered in 5q21-q22.
Ashton-Rickardt PG, et al.
Oncogene 4 : 1169-1174. 1989
110APC, D5S81, D5S82, D5S83, D5S84, D5S85, D5S86, FAP
Localization of the genetic defect in familial adenomatous polyposis within a small region of chromosome 5.
Nakamura Y, Lathrop M, Leppert M, Dobbs M, Wasmuth J, Wolff E, Carlson M, Fujimoto E, Krapcho K, Sears T, et al.
Am J Hum Genet 43 : 638-644. 1988
111APC, CHRPE, FAP
A genetic study of Gardner syndrome and congenital hypertrophy of the retinal pigment epithelium.
Lyons LA, et al.
Am J Hum Genet 42 : 290-296. 1988
112APC, FAP
Chromosome 5 allele loss at the glucocorticoid receptor locus in human colorectal carcinomas.
Wildrick DM, et al.
Biochem Biophys Res Commun 150 : 591-598. 1988
113APC, D5S37, D5S71, FAP
Close linkage of a highly polymorphic marker (D5S37) to familial adenomatous polyposis (FAP) and confirmation of FAP localization on chromosome 5q21-q22.
Meera Khan P, et al.
Hum Genet 79 : 183-185. 1988
114APC, D5S71, FAP
Localization of the gene for familial adenomatous polyposis on chromosome 5.
Bodmer WF, Bailey CJ, Bodmer J, Bussey HJ, Ellis A, Gorman P, Lucibello FC, Murday VA, Rider SH, Scambler P, et al.
Nature 328 : 614-616. 1987
115APC, D5S43, FAP
Chromosome 5 allele loss in human colorectal carcinomas.
Solomon E, Voss R, Hall V, Bodmer WF, Jass JR, Jeffreys AJ, Lucibello FC, Patel I, Rider SH.
Nature 328 : 616-619. 1987
116APC, D5S21, D5S22, D5S39, D5S70, D5S71, D5S74, D5S76, D5S78, FAP
The gene for familial polyposis coli maps to the long arm of chromosome 5.
Leppert M, et al.
Science 238 : 1411-1413. 1987
117APC, FAP
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118APC, FAP
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