Citations for
1FAF2, HMGCR
Haploid Mammalian Genetic Screen Identifies UBXD8 as a Key Determinant of HMGCR Degradation and Cholesterol Biosynthesis.
Loregger A, Raaben M, Tan J, Scheij S, Moeton M, van den Berg M, Gelberg-Etel H, Stickel E, Roitelman J, Brummelkamp T, Zelcer N.
Arterioscler Thromb Vasc Biol 37(11):2064-2074. doi: 10.1161/ATVBAHA.117.310002. Epub 2017 Sep 7. 2017
2FAF2, UBQLN2
Pathogenic mutation of UBQLN2 impairs its interaction with UBXD8 and disrupts endoplasmic reticulum-associated protein degradation.
Xia Y, Yan LH, Huang B, Liu M, Liu X, Huang C.
J Neurochem Neurochem. 2013 Nov 12. doi: 10.1111/jnc.12606. [Epub ahead of print] 2013
3FAF2, VCP
Spatial regulation of UBXD8 and p97/VCP controls ATGL-mediated lipid droplet turnover.
Olzmann JA, Richter CM, Kopito RR.
Proc Natl Acad Sci U S A 110(4):1345-50. doi: 10.1073/pnas.1213738110. Epub 2013 Jan 7. 2013
4APOB, DERL1, FAF2
Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets.
Suzuki M, Otsuka T, Ohsaki Y, Cheng J, Taniguchi T, Hashimoto H, Taniguchi H, Fujimoto T.
Mol Biol Cell 23(5):800-10. doi: 10.1091/mbc.E11-11-0950. Epub 2012 Jan 11. 2012
5FAF2
The ubiquitin-like (UBX)-domain-containing protein Ubx2/Ubxd8 regulates lipid droplet homeostasis.
Wang CW, Lee SC.
J Cell Sci 125(Pt 12):2930-9. doi: 10.1242/jcs.100230. Epub 2012 Mar 27. 2012
6FAF2, NF1
The RasGAP proteins Ira2 and neurofibromin are negatively regulated by Gpb1 in yeast and ETEA in humans.
Phan VT, Ding VW, Li F, Chalkley RJ, Burlingame A, McCormick F.
Mol Cell Biol 30(9):2264-79. Epub 2010 Feb 16.PMID: 20160012 2010
7FAF2
Identification of Ubxd8 protein as a sensor for unsaturated fatty acids and regulator of triglyceride synthesis.
Lee JN, Kim H, Yao H, Chen Y, Weng K, Ye J.
Proc Natl Acad Sci U S A 107(50):21424-9. Epub 2010 Nov 29. 2010
8AUP1, FAF2, OS9, SEL1L, UBE2J1
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.
Mueller B, Klemm EJ, Spooner E, Claessen JH, Ploegh HL.
Proc Natl Acad Sci U S A 105(34):12325-30. Epub 2008 Aug 18. 2008
9ACOT2, AFAP1L1, ALG11, ANKS1A, ARMC6, ARPC1A, ARPC3, ARPC5L, ATG10, ATP5L, BAZ1A, BCAS2, C2orf44, CAPZA1, CAPZA2, CCDC47, CERS2, CMBL, CPSF2, CSTF3, CXorf56, EXT2, FAF2, FBXO4, FIBP, GLRX3, GPS1, GSKIP, INPP5K, KPNA4, KRT31, KRT32, KRT33A, KRT33B, KRT34, KRT36, LUC7L2, MAGED1, MED7, MMS22L, MPRIP, MPRIP, MRCL3, NAA25, NDN, NPEPPS, NRDE2, OLA1, ORCTL3, OSTF1, PH4B, PIP5K1B, PKIG, PMVK, PSMC1, PSMC2, PSPH, RAB11FIP1, RBX1, RNF219, RO60, RPS14, SF3B14, SF3B2, SFRS12, STK25, TLK2, TONSL, TPM3, TRMT112, TSPAN17, TWF2, UBE2M, UNC45A, UQCRC1, WRAP73, XPO7, ZRANB2
Large-scale mapping of human protein-protein interactions by mass spectrometry.
Ewing RM, Chu P, Elisma F, Li H, Taylor P, Climie S, McBroom-Cerajewski L, Robinson MD, O'Connor L, Li M, Taylor R, Dharsee M, Ho Y, Heilbut A, Moore L, Zhang S, Ornatsky O, Bukhman YV, Ethier M, Sheng Y, Vasilescu J, Abu-Farha M, Lambert JP, Duewel HS, Stewart II, Kuehl B, Hogue K, Colwill K, Gladwish K, Muskat B, Kinach R, Adams SL, Moran MF, Morin GB, Topaloglou T, Figeys D.
Mol Syst Biol 3:89. Epub 2007 Mar 13. 2007
10FAF2
Cloning and characterization of the highly expressed ETEA gene from blood cells of atopic dermatitis patients.
Imai Y, Nakada A, Hashida R, Sugita Y, Tanaka T, Tsujimoto G, MatsumotoK, Akasawa A, Saito H, Oshida T.
Biochem Biophys Res Commun 297(5):1282-90. 2002
11ABLIM3, ABLIM3, ABLIM3, ADNP2, AHCYL2, ANKRD12, AP2A1, AP2A2, ARHGEF15, C20orf117, CLSTN1, CNKSR2, DHX30, DMXL2, EEF1AKNMT, EHBP1, FAF2, FBXO4, GOLGA8A, IVNS1ABP, LPHN1, MCF2L2, MLXIP, MORC2, NUP210, PCF11, PCYOX1, PNMA2, RAB11FIP5, RASGRP3, RHOBTB3, RUFY3, SACM1L, SCFD1, SEC31A, SLCO2B1, SLITRK3, UBOX5, USP19, WDR47, WWC1, ZC3H13, ZHX2, ZNF365
Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.
Nagase T, Ishikawa K, Suyama M, Kikuno R, Hirosawa M, Miyajima N, TanakaA, Kotani H, Nomura N, Ohara O.
DNA Res 5(6):355-64. 1998