1 | FADS2
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| Fatty acid desaturase 2 (FADS2) but not FADS1 desaturates branched chain and odd chain saturated fatty acids
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| Wang Z, Park HG, Wang DH, Kitano R, Kothapalli KSD, Brenna JT.
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| Biochim Biophys Acta Mol Cell Biol Lipids. Mar;1865(3):158572. doi: 10.1016/j.bbalip.2019.158572. Epub 2019 Nov 18. 2020
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2 | FADS1, FADS2
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| Liver DNA methylation of FADS2 associates with FADS2 genotype.
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| Walle P, Männistö V, de Mello VD, Vaittinen M, Perfilyev A, Hanhineva K, Ling C, Pihlajamäki J.
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| Clin Epigenetics. Jan 17;11(1):10. doi: 10.1186/s13148-019-0609-1. 2019
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3 | FADS1, FADS2
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| Tissue-specific impact of FADS cluster variants on FADS1 and FADS2 gene expression
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| Reynolds LM, Howard TD, Ruczinski I, Kanchan K, Seeds MC, Mathias RA, Chilton FH.
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| PLoS One. Mar 28;13(3):e0194610. doi: 10.1371/journal.pone.0194610. 2018
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4 | FADS1, FADS2
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| Polymorphisms in FADS1 and FADS2 alter plasma fatty acids and desaturase levels in type 2 diabetic patients with coronary artery disease
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| Li SW, Wang J, Yang Y, Liu ZJ, Cheng L, Liu HY, Ma P, Luo W, Liu SM.
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| J Transl Med. Mar 22;14:79. doi: 10.1186/s12967-016-0834-8. 2016
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5 | FADS1, FADS2, FADS3
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| Unsaturated fatty acids, desaturases, and human health.
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| Lee H, Park WJ.
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| J Med Food. Feb;17(2):189-97. doi: 10.1089/jmf.2013.2917. Epub 2014 Jan 24. 2014
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6 | FADS1, FADS2
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| A novel FADS1 isoform potentiates FADS2-mediated production of eicosanoid precursor fatty acids
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| Park WJ, Kothapalli KS, Reardon HT, Lawrence P, Qian SB, Brenna JT.
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| J Lipid Res. Aug;53(8):1502-12. doi: 10.1194/jlr.M025312. Epub 2012 May 22. 2012
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7 | FADS1, FADS2, FADS3
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| Fatty Acid Desaturase 3 (Fads3) is a singular member of the Fads cluster
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| Blanchard H, Legrand P, Pédrono F.
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| Biochimie. Jan;93(1):87-90. doi: 10.1016/j.biochi.2010.03.002. Epub 2010 Mar 11. 2011
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8 | FADS1, FADS2
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| Polymorphisms in FADS1 and FADS2 alter desaturase activity in young Caucasian and Asian adults.
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| Merino DM, Johnston H, Clarke S, Roke K, Nielsen D, Badawi A, El-Sohemy A, Ma DW, Mutch DM.
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| Mol Genet Metab. Jun;103(2):171-8. doi: 10.1016/j.ymgme.2011.02.012. Epub 2011 Feb 23 2011
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9 | FADS2
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| A common FADS2 promoter polymorphism increases promoter activity and facilitates binding of transcription factor ELK1
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| Lattka E, Eggers S, Moeller G, Heim K, Weber M, Mehta D, Prokisch H, Illig T, Adamski J.
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| J Lipid Res. Jan;51(1):182-91. doi: 10.1194/jlr.M900289-JLR200. 2010
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10 | FADS2
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| Regulation of human delta-6 desaturase gene transcription: identification of a functional direct repeat-1 element.
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| Tang C, Cho HP, Nakamura MT, Clarke SD.
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| J Lipid Res 44(4):686-95. Epub 2003 Jan 16. 2003
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11 | FADS2
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| A nucleotide insertion in the transcriptional regulatory region of FADS2 gives rise to human fatty acid delta-6-desaturase deficiency.
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| Nwankwo JO, Spector AA, Domann FE.
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| J Lipid Res 44(12):2311-9. Epub 2003 Sep 1. 2003
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12 | FADS2
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| The E-box like sterol regulatory element mediates the suppression of human Delta-6 desaturase gene by highly unsaturated fatty acids.
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| Nara TY, He WS, Tang C, Clarke SD, Nakamura MT.
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| Biochem Biophys Res Commun 296(1):111-7. 2002
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13 | FADS1, FADS2, FADS3
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| cDNA cloning, genomic structure, and chromosomal localization of three members of the human fatty acid desaturase family.
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| Marquardt A, Stohr H, White K, Weber BH.
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| Genomics 66(2):175-83. 2000
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14 | FADS1, FADS2
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| Cloning, expression, and fatty acid regulation of the human delta-5 desaturase.
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| Cho HP, Nakamura M, Clarke SD.
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| J Biol Chem 274(52):37335-9. 1999
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