Citations for
1EXTL2, EXTL3
Gene silencing of EXTL2 and EXTL3 as a substrate deprivation therapy for heparan sulphate storing mucopolysaccharidoses.
Kaidonis X, Liaw WC, Roberts AD, Ly M, Anson D, Byers S.
Eur J Hum Genet 18(2):194-9. doi: 10.1038/ejhg.2009.143. Epub 2009 Aug 19. 2010
2EXT1, EXT2, EXTL1, EXTL2, EXTL3
Human tumor suppressor EXT gene family members EXTL1 and EXTL3 encode alpha 1,4- N-acetylglucosaminyltransferases that likely are involved in heparan sulfate/ heparin biosynthesis.
Kim BT, Kitagawa H, Tamura J, Saito T, Kusche-Gullberg M, Lindahl U, Sugahara K.
Proc Natl Acad Sci U S A 98(13):7176-81. 2001
3EXTL2
The tumor suppressor EXT-like gene EXTL2 encodes an alpha1, 4-N-acetylhexosaminyltransferase that transfers N-acetylgalactosamine and N-acetylglucosamine to the common glycosaminoglycan-protein linkage region. The key enzyme for the chain initiation of heparan sulfate.
Kitagawa H, et al.
J Biol Chem 274(20):13933-7. 1999
4EXTL1, EXTL2, EXTL3
Identification of a new family of EXT-related genes. (abstr)
Wuyts W, et al.
Am J Hum Genet 61 : A351. 1997
5EXTL2, EXTL2P1
Identification and characterization of a novel member of the EXT gene family, EXTL2.
Wuyts W, Van Hul W, Hendrickx J, Speleman F, Wauters J, De Boulle K, Van Roy N, Van Agtmael T, Bossuyt P, Willems PJ.
Eur J Hum Genet 5(6):382-9. 1997