Citations for
1CASMN, EXOSC9
Variants in EXOSC9 Disrupt the RNA Exosome and Result in Cerebellar Atrophy with Spinal Motor Neuronopathy.
Burns DT, Donkervoort S, Müller JS, Knierim E, Bharucha-Goebel D, Faqeih EA, Bell SK, AlFaifi AY, Monies D, Millan F, Retterer K, Dyack S, MacKay S, Morales-Gonzalez S, Giunta M, Munro B, Hudson G, Scavina M, Baker L, Massini TC, Lek M, Hu Y, Ezzo D, AlKuraya FS, Kang PB, Griffin H, Foley AR, Schuelke M, Horvath R, Bönnemann CG.
Am J Hum Genet 102(5):858-873. doi: 10.1016/j.ajhg.2018.03.011. 2018
2EXOSC9, SETX
SETX sumoylation: A link between DNA damage and RNA surveillance disrupted in AOA2.
Richard P, Manley JL.
Rare Dis 2:e27744. doi: 10.4161/rdis.27744. eCollection 2014. 2014
3EXOSC9, SETX
A SUMO-dependent interaction between Senataxin and the exosome, disrupted in the neurodegenerative disease AOA2, targets the exosome to sites of transcription-induced DNA damage.
Richard P, Feng S, Manley JL.
Genes Dev 27(20):2227-32. doi: 10.1101/gad.224923.113. Epub 2013 Oct 8. 2013
4EXOSC9
Progenitor function in self-renewing human epidermis is maintained by the exosome.
Mistry DS, Chen Y, Sen GL.
Cell Stem Cell 11(1):127-35. doi: 10.1016/j.stem.2012.04.022. 2012
5EXOSC10, EXOSC9
Human cell growth requires a functional cytoplasmic exosome, which is involved in various mRNA decay pathways.
van Dijk EL, Schilders G, Pruijn GJ.
RNA 13(7):1027-35. Epub 2007 Jun 1. 2007
6EXOSC7, EXOSC9, EXOSC10
The association of the human PM/Scl-75 autoantigen with the exosome is dependent on a newly identified N terminus.
Raijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ.
J Biol Chem 278(33):30698-704. Epub 2003 Jun 04. 2003
7EXOSC1, EXOSC2, EXOSC3, EXOSC4, EXOSC5, EXOSC6, EXOSC7, EXOSC8, EXOSC9, EXOSC10, PNPT1
Protein-protein interactions between human exosome components support the assembly of RNase PH-type subunits into a six-membered PNPase-like ring.
Raijmakers R, Egberts WV, van Venrooij WJ, Pruijn GJ.
J Mol Biol 323(4):653-63. 2002
8EXOSC9
The mammalian exosome mediates the efficient degradation of mRNAs that contain AU-rich elements.
Mukherjee D, Gao M, O'Connor JP, Raijmakers R, Pruijn G, Lutz CS, Wilusz J.
EMBO J 21(1-2):165-74. 2002
9EXOSC2, EXOSC3, EXOSC4, EXOSC1, EXOSC5, EXOSC6, EXOSC7, EXOSC9, EXOSC10
AU binding proteins recruit the exosome to degrade ARE-containing mRNAs.
Chen CY, Gherzi R, Ong SE, Chan EL, Raijmakers R, Pruijn GJ, Stoecklin G, Moroni C, Mann M, Karin M.
Cell 107(4):451-64. 2001
10EXOSC9
Molecular characterization of an autoantigen of PM-Scl in the polymyositis/scleroderma overlap syndrome: a unique and complete human cDNA encoding an apparent 75-kD acidic protein of the nucleolar complex.
Alderuccio F, Chan EK, Tan EM.
J Exp Med 173(4):941-52. 1991