Citations for
1EXOC3, HSPB1, HSPB2, MAPK14
Sec6 enhances cell migration and suppresses apoptosis by elevating the phosphorylation of p38 MAPK, MK2, and HSP27.
Tanaka T, Iino M, Goto K.
Cell Signal 49:1-16. doi: 10.1016/j.cellsig.2018.04.009. Epub 2018 May 2. 2018
2BCL2, EXOC3, EXOC4, MCL1
Sec6/8 regulates Bcl-2 and Mcl-1, but not Bcl-xl, in malignant peripheral nerve sheath tumor cells.
Tanaka T, Kikuchi N, Goto K, Iino M.
Apoptosis 21(5):594-608. doi: 10.1007/s10495-016-1230-9. 2016
3EXOC3, NFKBIA, RPS6KA2
Nuclear Translocation of p65 is Controlled by Sec6 via the Degradation of IκBα.
Tanaka T, Iino M.
J Cell Physiol 231(3):719-30. doi: 10.1002/jcp.25122. 2016
4CDKN1B, COPS5, EXOC3, SIAH1
Sec6 regulated cytoplasmic translocation and degradation of p27 via interactions with Jab1 and Siah1.
Tanaka T, Iino M.
Cell Signal 26(10):2071-85. doi: 10.1016/j.cellsig.2014.06.003. Epub 2014 Jun 18. 2014
5AHRR, BRD9, CEP72, CLPTM1L, EXOC3, SLC6A3, SLC9A3, TPPP, TRIP13, ZDHHC11
Gain at chromosomal region 5p15.33, containing TERT, is the most frequent genetic event in early stages of non-small cell lung cancer.
Kang JU, Koo SH, Kwon KC, Park JW, Kim JM.
Cancer Genet Cytogenet 182(1):1-11.PMID: 18328944 2008
6EXOC2, EXOC3, EXOC4
Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.
Tsuboi T, Ravier MA, Xie H, Ewart MA, Gould GW, Baldwin SA, Rutter GA.
J Biol Chem 280(27):25565-70. Epub 2005 May 3.PMID: 15878854 2005
7EXOC1, EXOC3, EXOC4, EXOC7
The exocyst complex is required for targeting of Glut4 to the plasma membrane by insulin.
Inoue M, Chang L, Hwang J, Chiang SH, Saltiel AR.
Nature 422(6932):629-33.PMID: 12687004 2003
8EXOC3, EXOC4, EXOC8
Ral GTPases regulate exocyst assembly through dual subunit interactions.
Moskalenko S, Tong C, Rosse C, Mirey G, Formstecher E, Daviet L, Camonis J, White MA.
J Biol Chem 278(51):51743-8. Epub 2003 Oct 2.PMID: 14525976 2003
9EXOC3, EXOC4
Subunit composition, protein interactions, and structures of the mammalian brain sec6/8 complex and septin filaments.
Hsu SC, Hazuka CD, Roth R, Foletti DL, Heuser J, Scheller RH.
Neuron 20(6):1111-22.PMID: 9655500 1998
10ADCK2, ANAPC7, ARHGAP22, AVPI1, AZIN1, C12orf24, C14orf79, C5orf15, C9orf25, CNIH3, COG3, COG7, CREB3L1, DHX29, DHX57, DLAT, DLGAP3, EIF2B2, EXOC3, FAM13C1, FAM152B, FAM35A, FAM54B, FAM89B, FLAD1, GHITM, GRPEL1, HMGCLL1, IP6K2, IPO4, ITGB1BP1, KCMF1, KIFC2, LRP10, MDM1, MFN1, NAPG, NCALD, NECAB2, NPTN, NTNG2, PASK, PCDHB10, PHPT1, PI4K2A, PNPLA2, POGK, PTOV1, RNF41, SAC3D1, SDCBP2, SELT, SEMA6C, SLC38A6, SLC39A3, SMURF1, SPRED2, STX12, SUCLG2, TAX1BP3, TMEM183A, TP53I11, TRAPPC3, TRPC4AP, TSC22D3, TUBB, TXNDC12, UTP18, WDFY3, WDR40A, WDR77, WSB2, ZMIZ1, ZNF410, ZXDC
A double adaptor method for improved shotgun library construction.
Andersson B, Wentland MA, Ricafrente JY, Liu W, Gibbs RA.
Anal Biochem 236(1):107-13. 1996