| 1 | EXOC2, NEDFACH
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| Mutations in the exocyst component EXOC2 cause severe defects in human brain development.
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| Van Bergen NJ, Ahmed SM, Collins F, Cowley M, Vetro A, Dale RC, Hock DH, de Caestecker C, Menezes M, Massey S, Ho G, Pisano T, Glover S, Gusman J, Stroud DA, Dinger M, Guerrini R, Macara IG, Christodoulou J.
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| J Exp Med. Oct 5;217(10):e20192040. doi: 10.1084/jem.20192040 2020
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| 2 | EXOC2
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| Exocyst sec5 regulates exocytosis of newcomer insulin granules underlying biphasic insulin secretion
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| Xie L, Zhu D, Kang Y, Liang T, He Y, Gaisano HY.
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| PLoS One. Jul 2;8(7):e67561. doi: 10.1371/journal.pone.0067561. 2013
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| 3 | EXOC2, EXOC8, RALA
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| Sec5 and Exo84 mediate distinct aspects of RalA-dependent cell polarization
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| Hazelett CC, Yeaman C.
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| PLoS One. 7(6):e39602. doi: 10.1371/journal.pone.0039602. Epub 2012 Jun 22 2012
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| 4 | EXOC2
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| Exo84 and Sec5 are competitive regulatory Sec6/8 effectors to the RalA GTPase.
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| Jin R, Junutula JR, Matern HT, Ervin KE, Scheller RH, Brunger AT.
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| EMBO J 24(12):2064-74. Epub 2005 May 26. 2005
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| 5 | EXOC2, EXOC3, EXOC4
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| Mammalian exocyst complex is required for the docking step of insulin vesicle exocytosis.
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| Tsuboi T, Ravier MA, Xie H, Ewart MA, Gould GW, Baldwin SA, Rutter GA.
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| J Biol Chem 280(27):25565-70. Epub 2005 May 3.PMID: 15878854 2005
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| 6 | EXOC2, EXOC5
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| The exocyst complex in polarized exocytosis.
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| Hsu SC, TerBush D, Abraham M, Guo W.
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| Int Rev Cytol 233:243-65. Review. 2004
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| 7 | EXOC2
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| Mutations in the exocyst component Sec5 disrupt neuronal membrane traffic, but neurotransmitter release persists.
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| Murthy M, Garza D, Scheller RH, Schwarz TL.
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| Neuron 37(3):433-47. 2003
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| 8 | EXOC2
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| Structural basis of the interaction between RalA and Sec5, a subunit of the sec6/8 complex.
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| Fukai S, Matern HT, Jagath JR, Scheller RH, Brunger AT.
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| EMBO J 22(13):3267-78. 2003
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| 9 | EXOC2
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| DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion.
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| Sjolinder M, Uhlmann J, Ponstingl H.
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| FEBS Lett 532(1-2):211-5. 2002
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| 10 | EXOC2, SERGEF
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| DelGEF, a homologue of the Ran guanine nucleotide exchange factor RanGEF, binds to the exocyst component Sec5 and modulates secretion
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| Sjölinder M, Uhlmann J, Ponstingl H.
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| FEBS Lett. Dec 4;532(1-2):211-5. doi: 10.1016/s0014-5793(02)03677-3. 2002
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