Citations for
1ETV1
The Etv1 transcription factor activity-dependently downregulates a set of genes controlling cell growth and differentiation in maturing cerebellar granule cells.
Okazawa M, Abe H, Nakanishi S.
Biochem Biophys Res Commun 473(4):1071-7. doi: 10.1016/j.bbrc.2016.04.017. Epub 2016 Apr 5. 2016
2ETV1, KDM4A, YAP1
Histone demethylase JMJD2A drives prostate tumorigenesis through transcription factor ETV1.
Kim TD, Jin F, Shin S, Oh S, Lightfoot SA, Grande JP, Johnson AJ, van Deursen JM, Wren JD, Janknecht R.
J Clin Invest 126(2):706-20. doi: 10.1172/JCI78132. Epub 2016 Jan 5. 2016
3ETV1
ETV1 mRNA is specifically expressed in gastrointestinal stromal tumors.
Jang BG, Lee HE, Kim WH.
Virchows Arch 467(4):393-403. doi: 10.1007/s00428-015-1813-9. Epub 2015 Aug 5. 2015
4ETV1, EWSR1, FGF10
Etv1 and Ewsr1 cooperatively regulate limb mesenchymal Fgf10 expression in response to apical ectodermal ridge-derived fibroblast growth factor signal.
Yamamoto-Shiraishi Y, Higuchi H, Yamamoto S, Hirano M, Kuroiwa A.
Dev Biol 394(1):181-90. doi: 10.1016/j.ydbio.2014.07.022. Epub 2014 Aug 7. 2014
5ETV1
A small molecule that binds and inhibits the ETV1 transcription factor oncoprotein.
Pop MS, Stransky N, Garvie CW, Theurillat JP, Hartman EC, Lewis TA, Zhong C, Culyba EK, Lin F, Daniels DS, Pagliarini R, Ronco L, Koehler AN, Garraway LA.
Mol Cancer Ther 13(6):1492-502. doi: 10.1158/1535-7163.MCT-13-0689. Epub 2014 Apr 15. 2014
6ETV1, SNAI1
ETV1 induces epithelial to mesenchymal transition in human gastric cancer cells through the upregulation of Snail expression.
Li Z, Zhang L, Ma Z, Yang M, Tang J, Fu Y, Mao Y, Hong X, Zhang Y.
Oncol Rep 30(6):2859-63. doi: 10.3892/or.2013.2776. Epub 2013 Oct 2. 2013
7ETV1, MMP7
ETS variant 1 regulates matrix metalloproteinase-7 transcription in LNCaP prostate cancer cells.
Shin S, Oh S, An S, Janknecht R.
Oncol Rep 29(1):306-14. doi: 10.3892/or.2012.2079. Epub 2012 Oct 16. 2013
8ETV1, ETV4, ETV5
ETV1, 4 and 5: an oncogenic subfamily of ETS transcription factors.
Oh S, Shin S, Janknecht R.
Biochim Biophys Acta 1826(1):1-12. doi: 10.1016/j.bbcan.2012.02.002. Epub 2012 Mar 8. Review. 2012
9ETV1, GRIN2C, TIAM1
Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells.
Abe H, Okazawa M, Nakanishi S.
Proc Natl Acad Sci U S A 109(22):8734-9. doi: 10.1073/pnas.1206418109. Epub 2012 May 14. 2012
10ETV1
The Etv1/Er81 transcription factor orchestrates activity-dependent gene regulation in the terminal maturation program of cerebellar granule cells.
Abe H, Okazawa M, Nakanishi S.
Proc Natl Acad Sci U S A 108(30):12497-502. Epub 2011 Jul 11. 2011
11ETV1
Overexpression of full-length ETV1 transcripts in clinical prostate cancer due to gene translocation.
Gasi D, van der Korput HA, Douben HC, de Klein A, de Ridder CM, van Weerden WM, Trapman J.
PLoS One 6(1):e16332. 2011
12ETV1, ETV4, ETV5, RFWD2
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Vitari AC, Leong KG, Newton K, Yee C, O'Rourke K, Liu J, Phu L, Vij R, Ferrando R, Couto SS, Mohan S, Pandita A, Hongo JA, Arnott D, Wertz IE, Gao WQ, French DM, Dixit VM.
Nature 474(7351):403-6. doi: 10.1038/nature10005. 2011
13ETV1, POMC, TBX19
The Ets factor Etv1 interacts with Tpit protein for pituitary pro-opiomelanocortin (POMC) gene transcription.
Budry L, Couture C, Balsalobre A, Drouin J.
J Biol Chem 286(28):25387-96. Epub 2011 May 26. 2011
14ETV1, KIT
ETV1 is a lineage survival factor that cooperates with KIT in gastrointestinal stromal tumours.
Chi P, Chen Y, Zhang L, Guo X, Wongvipat J, Shamu T, Fletcher JA, Dewell S, Maki RG, Zheng D, Antonescu CR, Allis CD, Sawyers CL.
Nature 467(7317):849-53. Epub 2010 Oct 3. 2010
15ETV1
Differential regulation of dopaminergic gene expression by Er81.
Cave JW, Akiba Y, Banerjee K, Bhosle S, Berlin R, Baker H.
J Neurosci 30(13):4717-24. 2010
16ETV1
An oncogenic role for ETV1 in melanoma.
Jané-Valbuena J, Widlund HR, Perner S, Johnson LA, Dibner AC, Lin WM, Baker AC, Nazarian RM, Vijayendran KG, Sellers WR, Hahn WC, Duncan LM, Rubin MA, Fisher DE, Garraway LA.
Cancer Res 70(5):2075-84. Epub 2010 Feb 16. 2010
17ETV1
Characterization of ETS gene aberrations in select histologic variants of prostate carcinoma.
Han B, Mehra R, Suleman K, Tomlins SA, Wang L, Singhal N, Linetzky KA, Palanisamy N, Zhou M, Chinnaiyan AM, Shah RB.
Mod Pathol 22(9):1176-85. Epub 2009 May 22. 2009
18ETV1
Heterogeneity and clinical significance of ETV1 translocations in human prostate cancer.
Attard G, Clark J, Ambroisine L, Mills IG, Fisher G, Flohr P, Reid A, Edwards S, Kovacs G, Berney D, Foster C, Massie CE, Fletcher A, De Bono JS, Scardino P, Cuzick J, Cooper CS; Transatlantic Prostate Group.
Br J Cancer 99(2):314-20. Epub 2008 Jul 1. 2008
19ETV1, PAX6
Er81 is a downstream target of Pax6 in cortical progenitors.
Tuoc TC, Stoykova A.
BMC Dev Biol 8:23. 2008
20TMPRSS2, ETV1, ETV4
Gene fusions between TMPRSS2 and ETS family genes in prostate cancer: frequency and transcript variant analysis by RT-PCR and FISH on paraffin-embedded tissues.
Tu JJ, Rohan S, Kao J, Kitabayashi N, Mathew S, Chen YT.
Mod Pathol 20(9):921-8. Epub 2007 Jul 13. 2007
21ETV1
ETV1 is a novel androgen receptor-regulated gene that mediates prostate cancer cell invasion.
Cai C, Hsieh CL, Omwancha J, Zheng Z, Chen SY, Baert JL, Shemshedini L.
Mol Endocrinol 21(8):1835-46. Epub 2007 May 15. 2007
22TMPRSS2, ETV4, ETV1
TMPRSS2:ETV4 gene fusions define a third molecular subtype of prostate cancer.
Tomlins SA, Mehra R, Rhodes DR, Smith LR, Roulston D, Helgeson BE, Cao X, Wei JT, Rubin MA, Shah RB, Chinnaiyan AM.
Cancer Res 66(7):3396-400. 2006
23CIC, DUX4, ETV1
Fusion between CIC and DUX4 up-regulates PEA3 family genes in Ewing-like sarcomas with t(4;19)(q35;q13) translocation.
Kawamura-Saito M, Yamazaki Y, Kaneko K, Kawaguchi N, Kanda H, Mukai H, Gotoh T, Motoi T, Fukayama M, Aburatani H, Takizawa T, Nakamura T.
Hum Mol Genet 15(13):2125-37. Epub 2006 May 22. 2006
24ERG, ETV1, TMPRSS2
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM.
Science 310(5748):644-8. 2005
25ETV1
ETS gene Er81 controls the formation of functional connections between group Ia sensory afferents and motor neurons.
Arber S, Ladle DR, Lin JH, Frank E, Jessell TM.
Cell 101(5):485-98. 2000
26ETV1
Characterization of the human and mouse ETV1/ER81 transcription factor genes: role of the two alternatively spliced isoforms in the human.
Coutte L, Monte D, Imai K, Pouilly L, Dewitte F, Vidaud M, Adamski J, Baert JL, de Launoit Y.
Oncogene 18(46):6278-86. 1999
27ETV1, ETV5, ETV4
Genomic organization of the human ERM (ETV5) gene, a PEA3 group member of ETS transcription factors.
MontŽ D, et al.
Genomics 35 : 236-240. 1996
28ETV1
Molecular characterization of the ets-related human transcription factor ER81.
MontŽ D, et al.
Oncogene 11 : 771-779. 1995
29ETV1
A variant Ewing's sarcoma translocation (7;22) fuses the EWS gene to the ETS gene ETV1.
Jeon IS, et al.
Oncogene 10 : 1229-1234. 1995
30ETV1, ETV5, ETV4
Molecular cloning and characterization of human ERM, a new member of the Ets family closely related to mouse PEA3 and ER81 transcription factors.
MontŽ D, et al.
Oncogene 9 : 1397-1406. 1994
31ER71, ETV1, GABPA, GABPAP, GABPB1
Specificities of protein-protein and protein-DNA interaction of GABP alpha and two newly defined ets-related proteins.
Brown TA, McKnight SL.
Genes Dev 6(12B):2502-12 1992