| 1 | ESR1, NFATC1, WNT5B
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| Estrogen receptor alpha and NFATc1 bind to a bone mineral density-associated SNP to repress WNT5B in osteoblasts
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| Suthon S, Lin J, Perkins RS, Crockarell JR Jr, Miranda-Carboni GA, Krum SA.
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| Am J Hum Genet. Jan 6;109(1):97-115. doi: 10.1016/j.ajhg.2021.11.018. Epub 2021 Dec 13. 2022
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| 2 | ESR1, TNPO2
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| Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α.
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| Moriyama T, Yoneda Y, Oka M, Yamada M.
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| Sci Rep. Oct 29;10(1):18640. doi: 10.1038/s41598-020-75631-3. 2020
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| 3 | ESR1, SAFB, SAFB2
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| Scaffold attachment factor B: distribution and interaction with ERα in the rat brain.
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| Hashimoto T, Kawata M, Hirahara Y, Nishi M, Satoshi I, Matsuda KI.
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| Histochem Cell Biol. May;153(5):323-338. doi: 10.1007/s00418-020-01853-1. Epub 2020 Feb 21 2020
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| 4 | ESR1, NR5A1
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| Identification of a pituitary ERα-activated enhancer triggering the expression of Nr5a1, the earliest gonadotrope lineage-specific transcription factor.
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| Pacini V, Petit F, Querat B, Laverriere JN, Cohen-Tannoudji J, L'hôte D.
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| Epigenetics Chromatin. Aug 7;12(1):48. doi: 10.1186/s13072-019-0291-8. 2019
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| 5 | ESR1, HSP90AA1, PTGES3, SMYD2
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| A motif in HSP90 and P23 that links molecular chaperones to efficient estrogen receptor α methylation by the lysine methyltransferase SMYD2.
|
| Obermann WMJ.
|
| J Biol Chem 293(42):16479-16487. doi: 10.1074/jbc.RA118.003578. Epub 2018 Sep 6.
2018
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| 6 | ESR1, SAFB, SAFB2
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| Intranuclear Mobility of Estrogen Receptor: Implication for Transcriptional Regulation
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| Matsuda KI, Hashimoto T, Kawata M.
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| Acta Histochem Cytochem. Aug 29;51(4):129-136. doi: 10.1267/ahc.18023. Epub 2018 Aug 23. 2018
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| 7 | ESR1, KLK3
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| Crucial role of estrogen for the mammalian female in regulating semen coagulation and liquefaction in vivo.
|
| Li S, Garcia M, Gewiss RL, Winuthayanon W.
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| PLoS Genet 13(4):e1006743. doi: 10.1371/journal.pgen.1006743. eCollection 2017 Apr.
2017
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| 8 | DLX3, ESR1
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| Estrogen Receptor α Regulates Dlx3-Mediated Osteoblast Differentiation.
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| Lee SH, Oh KN, Han Y, Choi YH, Lee KY.
|
| Mol Cells 39(2):156-62. doi: 10.14348/molcells.2016.2291.
2016
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| 9 | CCNE1, ESR1, REL, TUBA1B
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| Identification of crucial genes related to postmenopausal osteoporosis using gene expression profiling
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| Ma M, Chen X, Lu L, Yuan F, Zeng W, Luo S, Yin F, Cai J.
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| Aging Clin Exp Res. Dec;28(6):1067-1074. doi: 10.1007/s40520-015-0509-y. Epub 2015 Dec 16. 2016
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| 10 | DFNB107, ESR1, PGR, WBP2
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| Wbp2 is required for normal glutamatergic synapses in the cochlea and is crucial for hearing.
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| Buniello A, Ingham NJ, Lewis MA, Huma AC, Martinez-Vega R, Varela-Nieto I, Vizcay-Barrena G, Fleck RA, Houston O, Bardhan T, Johnson SL, White JK, Yuan H, Marcotti W, Steel KP.
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| EMBO Mol Med. Mar 1;8(3):191-207. doi: 10.15252/emmm.201505523. 2016
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| 11 | ESR1, SRARP
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| ERRF is essential for Estrogen-Estrogen Receptor alpha signaling pathway in ER positive breast cancer cells.
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| Luo A, Zhang X.
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| Biochem Biophys Res Commun. May 27;474(2):400-405. doi: 10.1016/j.bbrc.2016.04.132. Epub 2016 Apr 26 2016
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| 12 | ESR1, FOXP1
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| The expression and correlation between the transcription factor FOXP1 and estrogen receptors in epithelial ovarian cancer.
|
| Hu Z, Zhu L, Tan M, Cai M, Deng L, Yu G, Liu D, Liu J, Lin B.
|
| Biochimie 109:42-8. doi: 10.1016/j.biochi.2014.12.001. Epub 2014 Dec 10.
2015
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| 13 | ESR1, UBR5
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| Systems level-based RNAi screening by high content analysis identifies UBR5 as a regulator of estrogen receptor-α protein levels and activity.
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| Bolt MJ, Stossi F, Callison AM, Mancini MG, Dandekar R, Mancini MA.
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| Oncogene 34(2):154-64. doi: 10.1038/onc.2013.550. Epub 2014 Jan 20.
2015
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| 14 | CAV1, ESR1
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| Increased coupling of caveolin-1 and estrogen receptor α contributes to the fragile X syndrome.
|
| Yang Q, Yang L, Zhang K, Guo YY, Liu SB, Wu YM, Li XQ, Song Q, Zhuo M, Zhao MG.
|
| Ann Neurol 77(4):618-36. doi: 10.1002/ana.24358. Epub 2015 Feb 26.
2015
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| 15 | ESR1, SUPT6H
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| SUPT6H controls estrogen receptor activity and cellular differentiation by multiple epigenomic mechanisms.
|
| Bedi U, Scheel AH, Hennion M, Begus-Nahrmann Y, Rüschoff J, Johnsen SA.
|
| Oncogene 34(4):465-73. doi: 10.1038/onc.2013.558.
2015
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| 16 | ESR1, PINX1
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| Novel role for PINX1 as a coregulator of nuclear hormone receptors.
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| Noriega-Reyes MY, Rivas-Torres MA, Oñate-Ocaña LF, Vallés AJ, Baranda-Avila N, Langley E.
|
| Mol Cell Endocrinol 414:9-18. doi: 10.1016/j.mce.2015.07.011. Epub 2015 Jul 15.
2015
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| 17 | ESR1, ESR2
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| Expression and subcellular localization of estrogen receptors α and β in human fetal brown adipose tissue.
|
| Velickovic K, Cvoro A, Srdic B, Stokic E, Markelic M, Golic I, Otasevic V, Stancic A, Jankovic A, Vucetic M, Buzadzic B, Korac B, Korac A.
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| J Clin Endocrinol Metab 99(1):151-9. doi: 10.1210/jc.2013-2017. Epub 2013 Dec 20.
2014
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| 18 | ESR1, IBSP
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| Unliganded estrogen receptor α stimulates bone sialoprotein gene expression.
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| Takai H, Matsumura H, Matsui S, Kim KM, Mezawa M, Nakayama Y, Ogata Y.
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| Gene 539(1):50-7. doi: 10.1016/j.gene.2014.01.063. Epub 2014 Feb 2.
2014
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| 19 | ESR1, HIF1A
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| HIF1α is required for osteoclast activation by estrogen deficiency in postmenopausal osteoporosis.
|
| Miyauchi Y, Sato Y, Kobayashi T, Yoshida S, Mori T, Kanagawa H, Katsuyama E, Fujie A, Hao W, Miyamoto K, Tando T, Morioka H, Matsumoto M, Chambon P, Johnson RS, Kato S, Toyama Y, Miyamoto T.
|
| Proc Natl Acad Sci U S A 110(41):16568-73. doi: 10.1073/pnas.1308755110. Epub 2013 Sep 10.
2013
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| 20 | EP300, ESR1, KDM1A, SMYD2
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| Regulation of estrogen receptor α by histone methyltransferase SMYD2-mediated protein methylation.
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| Zhang X, Tanaka K, Yan J, Li J, Peng D, Jiang Y, Yang Z, Barton MC, Wen H, Shi X.
|
| Proc Natl Acad Sci U S A 110(43):17284-9. doi: 10.1073/pnas.1307959110. Epub 2013 Oct 7.
2013
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| 21 | ESR1, HOXA7
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| Homeobox A7 stimulates breast cancer cell proliferation by up-regulating estrogen receptor-alpha.
|
| Zhang Y, Cheng JC, Huang HF, Leung PC.
|
| Biochem Biophys Res Commun 440(4):652-7. doi: 10.1016/j.bbrc.2013.09.121. Epub 2013 Oct 4.
2013
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| 22 | ESR1
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| ESR1 gene amplification in endometrial carcinomas: a clinicopathological analysis.
|
| Rahman MT, Nakayama K, Rahman M, Ishikawa M, Katagiri H, Katagiri A, Ishibashi T, Sato E, Iida K, Ishikawa N, Nakayama N, Miyazaki K.
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| Anticancer Res 33(9):3775-81.
2013
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| 23 | ESR1
|
| MEK5/ERK5 signaling suppresses estrogen receptor expression and promotes hormone-independent tumorigenesis.
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| Antoon JW, Martin EC, Lai R, Salvo VA, Tang Y, Nitzchke AM, Elliott S, Nam SY, Xiong W, Rhodes LV, Collins-Burow B, David O, Wang G, Shan B, Beckman BS, Nephew KP, Burow ME.
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| PLoS One 8(8):e69291. doi: 10.1371/journal.pone.0069291. eCollection 2013.
2013
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| 24 | ESR1, IGF1R, PDZK1
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| PDZK1 is a novel factor in breast cancer that is indirectly regulated by estrogen through IGF-1R and promotes estrogen-mediated growth.
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| Kim H, Abd Elmageed ZY, Ju J, Naura AS, Abdel-Mageed AB, Varughese S, Paul D, Alahari S, Catling A, Kim JG, Boulares AH.
|
| Mol Med 19:253-62. doi: 10.2119/molmed.2011.00001.
2013
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| 25 | ESR1, HDAC3
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| HDAC3 regulates stability of estrogen receptor α mRNA.
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| Oie S, Matsuzaki K, Yokoyama W, Murayama A, Yanagisawa J.
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| Biochem Biophys Res Commun 432(2):236-41. doi: 10.1016/j.bbrc.2013.02.007. Epub 2013 Feb 10.
2013
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| 26 | ESR1, LATS2
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| LATS2 is a modulator of estrogen receptor alpha.
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| Lit LC, Scott S, Zhang H, Stebbing J, Photiou A, Giamas G.
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| Anticancer Res 33(1):53-63.
2013
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| 27 | ESR1
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| Novel splicing events and post-transcriptional regulation of human estrogen receptor α E isoforms.
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| Ishii H, Kobayashi M, Munetomo A, Miyamoto T, Sakuma Y.
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| J Steroid Biochem Mol Biol 133:120-8. doi: 10.1016/j.jsbmb.2012.09.027. Epub 2012 Sep 29.
2013
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| 28 | ESR1, GREB1
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| Endogenous purification reveals GREB1 as a key estrogen receptor regulatory factor.
|
| Mohammed H, D'Santos C, Serandour AA, Ali HR, Brown GD, Atkins A, Rueda OM, Holmes KA, Theodorou V, Robinson JL, Zwart W, Saadi A, Ross-Innes CS, Chin SF, Menon S, Stingl J, Palmieri C, Caldas C, Carroll JS.
|
| Cell Rep 3(2):342-9. doi: 10.1016/j.celrep.2013.01.010. Epub 2013 Feb 9.
2013
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| 29 | CACUL1, ESR1, KDM1A
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| Negative regulation of ERα by a novel protein CAC1 through association with histone demethylase LSD1.
|
| Kim J, Park UH, Moon M, Um SJ, Kim EJ.
|
| FEBS Lett 587(1):17-22. doi: 10.1016/j.febslet.2012.10.054. Epub 2012 Nov 20.
2013
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| 30 | CARM1, ESR1, PELP1
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| PELP1 oncogenic functions involve CARM1 regulation.
|
| Mann M, Cortez V, Vadlamudi R.
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| Carcinogenesis 34(7):1468-75. doi: 10.1093/carcin/bgt091. Epub 2013 Mar 13.
2013
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| 31 | ESR1, RUNX3
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| RUNX3 acts as a tumor suppressor in breast cancer by targeting estrogen receptor α.
|
| Huang B, Qu Z, Ong CW, Tsang YH, Xiao G, Shapiro D, Salto-Tellez M, Ito K, Ito Y, Chen LF.
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| Oncogene 31(4):527-34. doi: 10.1038/onc.2011.252. Epub 2011 Jun 27.
2012
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| 32 | ESR1, RBCK1
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| Estrogen receptor-α, RBCK1, and protein kinase C β 1 cooperate to regulate estrogen receptor-α gene expression.
|
| Gustafsson Sheppard N, Heldring N, Dahlman-Wright K.
|
| J Mol Endocrinol 49(3):277-87. doi: 10.1530/JME-12-0073. Print 2012 Dec.
2012
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| 33 | ESR1
|
| Rapid changes in cardiac myofilament function following the acute activation of estrogen receptor-alpha.
|
| Kulpa J, Chinnappareddy N, Pyle WG.
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| PLoS One 7(7):e41076. doi: 10.1371/journal.pone.0041076. Epub 2012 Jul 30.
2012
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| 34 | ESR1, TP53
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| p53, a target of estrogen receptor (ER) α, modulates DNA damage-induced growth suppression in ER-positive breast cancer cells.
|
| Berger CE, Qian Y, Liu G, Chen H, Chen X.
|
| J Biol Chem 287(36):30117-27. doi: 10.1074/jbc.M112.367326. Epub 2012 Jul 11.
2012
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| 35 | ESR1
|
| A DNA binding mutation in estrogen receptor-α leads to suppression of Wnt signaling via β-catenin destabilization in osteoblasts.
|
| Mödder UI, Rudnik V, Liu G, Khosla S, Monroe DG.
|
| J Cell Biochem 113(7):2248-55. doi: 10.1002/jcb.24095.
2012
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| 36 | ESR1, GREB1, NR5A2
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| The orphan nuclear receptor LRH-1 and ERα activate GREB1 expression to induce breast cancer cell proliferation.
|
| Chand AL, Wijayakumara DD, Knower KC, Herridge KA, Howard TL, Lazarus KA, Clyne CD.
|
| PLoS One 7(2):e31593. doi: 10.1371/journal.pone.0031593. Epub 2012 Feb 16.
2012
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| 37 | ESR1, SAFB, SAFB2
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| Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.
|
| Hashimoto T, Matsuda K, Kawata M.
|
| J Cell Biochem 113(9):3039-50. doi: 10.1002/jcb.24182.
2012
|
| 38 | ESR1, ESR2, HADHB
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| Estrogen receptor beta interacts and colocalizes with HADHB in mitochondria.
|
| Zhou Z, Zhou J, Du Y.
|
| Biochem Biophys Res Commun 427(2):305-8. doi: 10.1016/j.bbrc.2012.09.047. Epub 2012 Sep 18.
2012
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| 39 | ESR1, ZFHX3
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| Estrogen up-regulates ATBF1 transcription but causes its protein degradation in estrogen receptor-alpha-positive breast cancer cells.
|
| Dong XY, Guo P, Sun X, Li Q, Dong JT.
|
| J Biol Chem 286(16):13879-90. Epub 2011 Mar 2.
2011
|
| 40 | C6ORF211, ESR1, ST8
|
| ESR1 is co-expressed with closely adjacent uncharacterised genes spanning a breast cancer susceptibility locus at 6q25.1.
|
| Dunbier AK, Anderson H, Ghazoui Z, Lopez-Knowles E, Pancholi S, Ribas R, Drury S, Sidhu K, Leary A, Martin LA, Dowsett M.
|
| PLoS Genet 7(4):e1001382. Epub 2011 Apr 28.
2011
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| 41 | ESR1, ESR2, HOXB9, KMT2A, KMT2C
|
| Histone methylases MLL1 and MLL3 coordinate with estrogen receptors in estrogen-mediated HOXB9 expression.
|
| Ansari KI, Shrestha B, Hussain I, Kasiri S, Mandal SS.
|
| Biochemistry 50(17):3517-27. Epub 2011 Apr 5. 2011
|
| 42 | CRKL, ESR1
|
| CrkL is a co-activator of estrogen receptor alpha that enhances tumorigenic potential in cancer.
|
| Padmanabhan RA, Nirmala L, Murali M, Laloraya M.
|
| Mol Endocrinol 25(9):1499-512. doi: 10.1210/me.2011-0008. Epub 2011 Jun 23.
2011
|
| 43 | ESR1, KAT5
|
| Recognition of enhancer element-specific histone methylation by TIP60 in transcriptional activation.
|
| Jeong KW, Kim K, Situ AJ, Ulmer TS, An W, Stallcup MR.
|
| Nat Struct Mol Biol 18(12):1358-65. doi: 10.1038/nsmb.2153.
2011
|
| 44 | ESR1, FLI1
|
| Fli1 is a negative regulator of estrogen receptor α in dermal fibroblasts.
|
| Hattori T, Stawski L, Nakerakanti SS, Trojanowska M.
|
| J Invest Dermatol 131(7):1469-76. doi: 10.1038/jid.2011.63. Epub 2011 Mar 31.
2011
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| 45 | ESR1, RPS6KA1, RPS6KB1
|
| mTOR/S6K1 and MAPK/RSK signaling pathways coordinately regulate estrogen receptor alpha serine 167 phosphorylation.
|
| Yamnik RL, Holz MK.
|
| FEBS Lett 584(1):124-8. Epub .
2010
|
| 46 | ESR1, ESR2, LRP4, LRP5, SOST, TNFRSF11A, TNFRSF11B, TNFSF11, VDR, WLS
|
| Genetics of osteoporosis: accelerating pace in gene identification and validation.
|
| Li WF, Hou SX, Yu B, Li MM, Férec C, Chen JM.
|
| Hum Genet 127(3):249-85. Epub 2009 Dec 12. Review.PMID: 20101412 2010
|
| 47 | CARM1, ESR1
|
| CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor alpha by cAMP.
|
| Carascossa S, Dudek P, Cenni B, Briand PA, Picard D.
|
| Genes Dev 24(7):708-19.PMID: 20360387 2010
|
| 48 | ESR1, MYCN
|
| MYCN-regulated microRNAs repress estrogen receptor-alpha (ESR1) expression and neuronal differentiation in human neuroblastoma.
|
| Lovén J, Zinin N, Wahlström T, Müller I, Brodin P, Fredlund E, Ribacke U, Pivarcsi A, Påhlman S, Henriksson M.
|
| Proc Natl Acad Sci U S A 107(4):1553-8. Epub 2010 Jan 4.
2010
|
| 49 | ATF3, ESR1, ESR2, SRD5A2
|
| Genetics of hypospadias: are single-nucleotide polymorphisms in SRD5A2, ESR1, ESR2, and ATF3 really associated with the malformation?
|
| van der Zanden LF, van Rooij IA, Feitz WF, Vermeulen SH, Kiemeney LA, Knoers NV, Roeleveld N, Franke B.
|
| J Clin Endocrinol Metab 95(5):2384-90. Epub 2010 Mar 9.PMID: 20215396 2010
|
| 50 | ADAM10, ESR1
|
| EGCG functions through estrogen receptor-mediated activation of ADAM10 in the promotion of non-amyloidogenic processing of APP.
|
| Fernandez JW, Rezai-Zadeh K, Obregon D, Tan J.
|
| FEBS Lett 584(19):4259-67. Epub 2010 Sep 17.
2010
|
| 51 | ESR1, ESR2, NCOA2, PGR, SRCOA2
|
| Steroid receptor coactivator-2 expression in brain and physical associations with steroid receptors.
|
| Yore MA, Im D, Webb LK, Zhao Y, Chadwick JG Jr, Molenda-Figueira HA, Haidacher SJ, Denner L, Tetel MJ.
|
| Neuroscience 169(3):1017-28. Epub 2010 Jun 2. 2010
|
| 52 | ESR1, TUSC3
|
| DNA methylation of ESR-1 and N-33 in colorectal mucosa of patients with ulcerative colitis (UC).
|
| Arasaradnam RP, Khoo K, Bradburn M, Mathers JC, Kelly SB.
|
| Epigenetics 5(5):422-6. Epub 2010 Jul 1.
2010
|
| 53 | C6orf97, ESR1
|
| Genome-wide association study identifies a new breast cancer susceptibility locus at 6q25.1.
|
| Zheng W, Long J, Gao YT, Li C, Zheng Y, Xiang YB, Wen W, Levy S, Deming SL, Haines JL, Gu K, Fair AM, Cai Q, Lu W, Shu XO.
|
| Nat Genet 41(3):324-8. Epub 2009 Feb 15. 2009
|
| 54 | ESR1, SIN3A
|
| Repression of ESR1 through actions of estrogen receptor alpha and Sin3A at the proximal promoter.
|
| Ellison-Zelski SJ, Solodin NM, Alarid ET.
|
| Mol Cell Biol 29(18):4949-58. Epub 2009 Jul 20.
2009
|
| 55 | ESR1, RPS6KB1
|
| S6 kinase 1 regulates estrogen receptor alpha in control of breast cancer cell proliferation.
|
| Yamnik RL, Digilova A, Davis DC, Brodt ZN, Murphy CJ, Holz MK.
|
| J Biol Chem 284(10):6361-9. Epub 2008 Dec 27.
2009
|
| 56 | ACTL6A, ESR1, FLII
|
| Recruitment of the SWI/SNF chromatin remodeling complex to steroid hormone-regulated promoters by nuclear receptor coactivator flightless-I.
|
| Jeong KW, Lee YH, Stallcup MR.
|
| J Biol Chem 284(43):29298-309. doi: 10.1074/jbc.M109.037010. Epub 2009 Aug 31. 2009
|
| 57 | ESR1, SMYD3
|
| Requirement of histone methyltransferase SMYD3 for estrogen receptor-mediated transcription.
|
| Kim H, Heo K, Kim JH, Kim K, Choi J, An W.
|
| J Biol Chem 284(30):19867-77. doi: 10.1074/jbc.M109.021485. Epub 2009 Jun 9.
2009
|
| 58 | ESR1, PRKN
|
| Evaluation of a SNP map of 6q24-27 confirms diabetic nephropathy loci and identifies novel associations in type 2 diabetes patients with nephropathy from an African-American population.
|
| Leak TS, Mychaleckyj JC, Smith SG, Keene KL, Gordon CJ, Hicks PJ, Freedman BI, Bowden DW, Sale MM.
|
| Hum Genet 124(1):63-71. Epub 2008 Jun 17. 2008
|
| 59 | ESR1, ESR2, NFATC4
|
| Repression of NFAT3 transcriptional activity by estrogen receptors.
|
| Qin X, Wang XH, Yang ZH, Ding LH, Xu XJ, Cheng L, Niu C, Sun HW, Zhang H, Ye QN.
|
| Cell Mol Life Sci 65(17):2752-62.
2008
|
| 60 | ESR1
|
| Identification of a 2244 base pair interstitial deletion within the human ESR1 gene in the Spanish population.
|
| Galan JJ, Buch B, Pedrinaci S, Jimenez-Gamiz P, Gonzalez A, Serrano-Rios M, Salinas A, Rivero Mdel C, Real LM, Royo JL, Ruiz A.
|
| J Med Genet 45(7):420-4. Epub 2008 Apr 18.
2008
|
| 61 | ESR1, ESR2
|
| Genetic polymorphisms of ESR1 and ESR2 that may influence estrogen activity and the risk of hypospadias.
|
| Ban S, Sata F, Kurahashi N, Kasai S, Moriya K, Kakizaki H, Nonomura K, Kishi R.
|
| Hum Reprod 23(6):1466-71. Epub 2008 Mar 27.PMID: 18375409 2008
|
| 62 | BTF3, ESR1
|
| Interaction between transcription factor, basal transcription factor 3, and the NH2-terminal domain of human estrogen receptor alpha.
|
| Green CD, Thompson PD, Johnston PG, El-Tanani MK.
|
| Mol Cancer Res 5(11):1191-200.
2007
|
| 63 | ESR1
|
| Estrogen receptor alpha (ESR1) gene amplification is frequent in breast cancer.
|
| Holst F, Stahl PR, Ruiz C, Hellwinkel O, Jehan Z, Wendland M, Lebeau A, Terracciano L, Al-Kuraya K, Janicke F, Sauter G, Simon R.
|
| Nat Genet 39(5):655-60. Epub 2007 Apr 8. 2007
|
| 64 | BRCA1, ESR1, PGR, PYCARD
|
| Promoter hypermethylation of TMS1, BRCA1, ERalpha and PRB in serum and tumor DNA of invasive ductal breast carcinoma patients.
|
| Mirza S, Sharma G, Prasad CP, Parshad R, Srivastava A, Gupta SD, Ralhan R.
|
| Life Sci 81(4):280-7. Epub 2007 May 25. 2007
|
| 65 | GREB1, ESR1
|
| Regulation of GREB1 transcription by estrogen receptor alpha through a multipartite enhancer spread over 20 kb of upstream flanking sequences.
|
| Deschnes J, Bourdeau V, White JH, Mader S.
|
| J Biol Chem 282(24):17335-9. Epub 2007 Apr 26. 2007
|
| 66 | ACE, APOE, CHRNB2, CST3, ESR1, GAPDHS, IDE, MTHFR, NCSTN, PRNP, PSEN1, TF, TFAM, TNF
|
| Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database.
|
| Bertram L, McQueen MB, Mullin K, Blacker D, Tanzi RE.
|
| Nat Genet 39(1):17-23. 2007
|
| 67 | ESR1
|
| The DNA binding domain of estrogen receptor alpha is required for high-affinity nuclear interaction induced by estradiol.
|
| Weinberg AL, Carter D, Ahonen M, Alarid ET, Murdoch FE, Fritsch MK.
|
| Biochemistry 46(31):8933-42. Epub 2007 Jul 14.
2007
|
| 68 | SAFB, SAFB2, ESR1
|
| Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha-mediated transcription in part via interaction with nuclear receptor corepressor.
|
| Jiang S, Meyer R, Kang K, Osborne CK, Wong J, Oesterreich S.
|
| Mol Endocrinol 20(2):311-20. Epub 2005 Sep 29. 2006
|
| 69 | ESR1, KMT2D
|
| Identification of the MLL2 complex as a coactivator for estrogen receptor alpha.
|
| Mo R, Rao SM, Zhu YJ.
|
| J Biol Chem 281(23):15714-20. Epub 2006 Apr 7.PMID: 16603732 2006
|
| 70 | BARX2, ESR1
|
| BARX2 and estrogen receptor-alpha (ESR1) coordinately regulate the production of alternatively spliced ESR1 isoforms and control breast cancer cell growth and invasion.
|
| Stevens TA, Meech R.
|
| Oncogene 25(39):5426-35. Epub 2006 Apr 24.
2006
|
| 71 | ESR1
|
| Ciz1, a Novel DNA-binding coactivator of the estrogen receptor alpha, confers hypersensitivity to estrogen action.
|
| den Hollander P, Rayala SK, Coverley D, Kumar R.
|
| Cancer Res 66(22):11021-9.
2006
|
| 72 | CNOT1, ESR1
|
| Human Ccr4-Not complex is a ligand-dependent repressor of nuclear receptor-mediated transcription.
|
| Winkler GS, Mulder KW, Bardwell VJ, Kalkhoven E, Timmers HT.
|
| EMBO J 25(13):3089-99. Epub 2006 Jun 15.
2006
|
| 73 | ESR1
|
| Association of oestrogen receptor {alpha} gene polymorphisms with postmenopausal bone loss, bone mass, and quantitative ultrasound properties of bone.
|
| Albagha OM, Pettersson U, Stewart A, McGuigan FE, Macdonald HM, Reid DM, Ralston SH.
|
| J Med Genet 42(3):240-6. 2005
|
| 74 | C21orf129, ESR1, FOXA1
|
| Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.
|
| Carroll JS, Liu XS, Brodsky AS, Li W, Meyer CA, Szary AJ, Eeckhoute J, Shao W, Hestermann EV, Geistlinger TR, Fox EA, Silver PA, Brown M.
|
| Cell 122(1):33-43. 2005
|
| 75 | FOXA1, ESR1, TFF1
|
| From the Cover: Location analysis of estrogen receptor {alpha} target promoters reveals that FOXA1 defines a domain of the estrogen response.
|
| Laganiere J, Deblois G, Lefebvre C, Bataille AR, Robert F, Giguere V.
|
| Proc Natl Acad Sci U S A 102(33):11651-6. Epub 2005 Aug 8. 2005
|
| 76 | ESR1
|
| The oestrogen receptor alpha gene is linked and/or associated with age of menarche in different ethnic groups.
|
| Long JR, Xu H, Zhao LJ, Liu PY, Shen H, Liu YJ, Xiong DH, Xiao P, Liu YZ, Dvornyk V, Li JL, Recker RR, Deng HW.
|
| J Med Genet 42(10):796-800. No abstract available. 2005
|
| 77 | ESR1
|
| Association of cryptorchidism with a specific haplotype of the estrogen receptor alpha gene: implication for the susceptibility to estrogenic environmental endocrine disruptors.
|
| Yoshida R, Fukami M, Sasagawa I, Hasegawa T, Kamatani N, Ogata T.
|
| J Clin Endocrinol Metab 90(8):4716-21. Epub 2005 May 17. 2005
|
| 78 | ESR1, NCOA4
|
| Endogenous coactivator ARA70 interacts with estrogen receptor alpha (ERalpha) and modulates the functional ERalpha/androgen receptor interplay in MCF-7 cells.
|
| Lanzino M, De Amicis F, McPhaul MJ, Marsico S, Panno ML, Andò S.
|
| J Biol Chem 280(21):20421-30. Epub 2005 Mar 15.
2005
|
| 79 | ESR1, ESR2, HMGA1
|
| The functional interaction between HMGA1 and the estrogen receptor requires either the N- or the C-terminal domain of the receptor.
|
| Massaad-Massade L, Tacine R, Dulauroy S, Reeves R, Barouki R.
|
| FEBS Lett 559(1-3):89-95. 2004
|
| 80 | ESR1, ESR2, DNTTIP2
|
| ERBP, a novel estrogen receptor binding protein enhancing the activity of estrogen receptor.
|
| Bu H, Kashireddy P, Chang J, Zhu YT, Zhang Z, Zheng W, Rao SM, Zhu YJ.
|
| Biochem Biophys Res Commun 317(1):54-9. 2004
|
| 81 | PELP1, ESR1, ESR2
|
| Cloning and functional characterization of PELP1/MNAR promoter.
|
| Mishra SK, Balasenthil S, Nguyen D, Vadlamudi RK.
|
| Gene 330:115-22. 2004
|
| 82 | ESR1
|
| Age-dependent methylation of ESR1 gene in prostate cancer.
|
| Li LC, Shiina H, Deguchi M, Zhao H, Okino ST, Kane CJ, Carroll PR, Igawa M, Dahiya R.
|
| Biochem Biophys Res Commun 321(2):455-61. 2004
|
| 83 | ESR1, ESR2, TADA3
|
| Human ADA3 binds to estrogen receptor (ER) and functions as a coactivator for ER-mediated transactivation.
|
| Meng G, Zhao Y, Nag A, Zeng M, Dimri G, Gao Q, Wazer DE, Kumar R, Band H, Band V.
|
| J Biol Chem 279(52):54230-40. Epub 2004 Oct 20. 2004
|
| 84 | ESR1, STRN
|
| Striatin assembles a membrane signaling complex necessary for rapid, nongenomic activation of endothelial NO synthase by estrogen receptor alpha.
|
| Lu Q, Pallas DC, Surks HK, Baur WE, Mendelsohn ME, Karas RH.
|
| Proc Natl Acad Sci U S A 101(49):17126-31. Epub 2004 Nov 29.
2004
|
| 85 | SMAD4, SMAD1, SMAD2, SMAD3, ESR1
|
| Smad4 as a transcription corepressor for estrogen receptor alpha.
|
| Wu L, Wu Y, Gathings B, Wan M, Li X, Grizzle W, Liu Z, Lu C, Mao Z, Cao X.
|
| J Biol Chem 278(17):15192-200. Epub 2003 Feb 07. 2003
|
| 86 | BRCA1, EP300, ESR1
|
| p300 Modulates the BRCA1 inhibition of estrogen receptor activity.
|
| Fan S, Ma YX, Wang C, Yuan RQ, Meng Q, Wang JA, Erdos M, Goldberg ID, Webb P, Kushner PJ, Pestell RG, Rosen EM.
|
| Cancer Res 62(1):141-51. 2002
|
| 87 | ESR1
|
| MAP kinase mediates growth factor-induced nuclear translocation of estrogen receptor alpha.
|
| Lu Q, Ebling H, Mittler J, Baur WE, Karas RH.
|
| FEBS Lett 516(1-3):1-8. 2002
|
| 88 | ESR1
|
| Alteration of large-scale chromatin structure by estrogen receptor.
|
| Nye AC, Rajendran RR, Stenoien DL, Mancini MA, Katzenellenbogen BS, Belmont AS.
|
| Mol Cell Biol 22(10):3437-49. 2002
|
| 89 | ESR1, ZNF398
|
| A novel zinc finger transcription factor with two isoforms that are differentially repressed by estrogen receptor-alpha.
|
| Conroy AT, Sharma M, Holtz AE, Wu C, Sun Z, Weigel RJ.
|
| J Biol Chem 277(11):9326-34. 2002
|
| 90 | CARM1, ESR1, PRMT2, NCOA2, NCOA6
|
| Identification of protein arginine methyltransferase 2 as a coactivator for estrogen receptor alpha.
|
| Qi C, Chang J, Zhu Y, Yeldandi AV, Rao SM, Zhu YJ.
|
| J Biol Chem 277(32):28624-30. 2002
|
| 91 | ESR1, ESR2
|
| Identification of ten exon deleted ERbeta mRNAs in human ovary, breast, uterus and bone tissues: alternate splicing pattern of estrogen receptor beta mRNA is distinct from that of estrogen receptor alpha.
|
| Poola I, Abraham J, Baldwin K.
|
| FEBS Lett 516(1-3):133-8. 2002
|
| 92 | ESR1
|
| A novel promoter is involved in the expression of estrogen receptor alpha in human testis and epididymis.
|
| Brand H, Kos M, Denger S, Flouriot G, Gromoll J, Gannon F, Reid G.
|
| Endocrinology 143(9):3397-404. 2002
|
| 93 | ESR1
|
| Estrogen receptors in human preadipocytes.
|
| Joyner JM, Hutley LJ, Cameron DP.
|
| Endocrine 15(2):225-30. 2001
|
| 94 | ESR1
|
| Genomic structure of the promoters of the human estrogen receptor-alpha gene demonstrate changes in chromatin structure induced by AP2gamma.
|
| Schuur ER, McPherson LA, Yang GP, Weigel RJ.
|
| J Biol Chem 276(18):15519-26. 2001
|
| 95 | ESR1, ESR2
|
| Expression, function, and clinical implications of the estrogen receptor beta in human lung cancers.
|
| Omoto Y, Kobayashi Y, Nishida K, Tsuchiya E, Eguchi H, Nakagawa K, Ishikawa Y, Yamori T, Iwase H, Fujii Y, Warner M, Gustafsson JA, Hayashi SI.
|
| Biochem Biophys Res Commun 285(2):340-7. 2001
|
| 96 | ESR1
|
| ERalpha gene expression in human primary osteoblasts: evidence for the expression of two receptor proteins
|
| Denger S, Reid G, Kos M, Flouriot G, Parsch D, Brand H, Korach KS, Sonntag-Buck V, Gannon F.
|
| Mol Endocrinol 15(12):2064-77. 2001
|
| 97 | ESR1
|
| Identification of a new isoform of the human estrogen receptor-alpha (hER-alpha) that is encoded by distinct transcripts and that is able to repress hER-alpha activation function 1.
|
| Flouriot G, Brand H, Denger S, Metivier R, Kos M, Reid G, Sonntag-Buck V, Gannon F.
|
| EMBO J 19(17):4688-4700. 2000
|
| 98 | ESR1
|
| Evidence of a linkage disequilibrium between polymorphisms in the human estrogen receptor alpha gene and their relationship to bone mass variation in postmenopausal Italian women.
|
| Becherini L, Gennari L, Masi L, Mansani R, Massart F, Morelli A, Falchetti A, Gonnelli S, Fiorelli G, Tanini A, Brandi ML.
|
| Hum Mol Genet 9(13):2043-50. 2000
|
| 99 | ESR1
|
| Identification of a novel FAS/ER-alpha fusion transcript expressed in human cancer cells.
|
| Ye Q, Chung LW, Li S, Zhau HE.
|
| Biochim Biophys Acta 1493(3):373-7. 2000
|
| 100 | ESR1
|
| Alternative initiation of translation accounts for a 67/45 kDa dimorphism of the human estrogen receptor ERalpha.
|
| Barraille P, et al.
|
| Biochem Biophys Res Commun 257(1):84-8. 1999
|
| 101 | ESR1
|
| Association of the estrogen receptor alpha gene polymorphisms with sporadic Alzheimer's disease.
|
| Brandi ML, Becherini L, Gennari L, Racchi M, Bianchetti A, Nacmias B, Sorbi S, Mecocci P, Senin U, Govoni S.
|
| Biochem Biophys Res Commun 265(2):335-8. 1999
|
| 102 | ESR1, VDR
|
| Change of bone mass in postmenopausal Caucasian women with and without hormone replacement therapy is associated with vitamin D receptor and estrogen receptor genotypes.
|
| Deng HW, et al.
|
| Hum Genet 103 : 576-585. 1998
|
| 103 | ESR1
|
| Cloning and characterization of 77-kDa oestrogen receptor isolated from a human breast cancer cell line. Cloning of the wild-type ER and ER77 full-length cDNAs.
|
| Pink JJ, et al.
|
| Br J Cancer 75 : 17-27. 1997
|
| 104 | ESR1
|
| Screening for ESR mutations in breast and ovarian cancer patients.
|
| Anderson TI, Wooster R, Laake K, Collins N, Warren W, Skrede M, Elles R, Tveit KM, Johnston SR, Dowsett M, Olsen AO, Moller P, Stratton MR, Borresen-Dale AL.
|
| Hum Mutat 9(6):531-6. 1997
|
| 105 | ESR1, ESR
|
| Premature coronary artery disease associated with a disruptive mutation in the estrogen receptor gene in a man.
|
| Sudhir K, Chou TM, Chatterjee K, Smith EP, Williams TC, Kane JP, Malloy MJ, Korach KS, Rubanyi GM.
|
| Circulation 96(10):3774-7. 1997
|
| 106 | ESR1
|
| Mutations in the estrogen receptor gene.
|
| Sluyser M.
|
| Hum Mutat 6 : 97-103. 1995
|
| 107 | ESR1
|
| Estrogen resistance caused by a mutation in the estrogen-receptor gene in a man.
|
| Smith EP, et al.
|
| N Engl J Med 331 : 1056-1061. 1994
|
| 108 | ESR1
|
| Localization of the estrogen receptor locus (ESR) to chromosome 6q25.1 by FISH and a simple post-FISH banding technique.
|
| Menasce LP, et al.
|
| Genomics 17 : 263-265. 1993
|
| 109 | ESR1, ESR2, ESRRA, ESRRB, ESRRG, NR3C1
|
| The crystal structure of the estrogen receptor DNA-binding domain bound to DNA: how receptors discriminate between their response elements.
|
| Schwabe JW, et al.
|
| Cell 75(3):567-78 1993
|
| 110 | ESR1
|
| Dinucleotide repeat polymorphism in the human estrogen receptor (ESR) gene.
|
| del Senno L, et al.
|
| Hum Mol Genet 1 : 354. 1992
|
| 111 | ESR1
|
| Aberrant oestrogen receptor species in human meningioma tissue.
|
| Koehorst SGA, et al.
|
| J Steroid Biochem Mol Biol 43 : 57-61. 1992
|
| 112 | ESR1
|
| Polymorphisms at the estrogen receptor (ESR) locus and linkage relationships on chromosome 6q.
|
| Zuppan PJ, et al.
|
| (HGM10) Cytogenet Cell Genet 51 : 1116. 1989
|
| 113 | ESR1
|
| Human estrogen receptor (ESR) gene locus : PssI dimorphism.
|
| Coleman RT, et al.
|
| Nucleic Acids Res 16 : 7208. 1988
|
| 114 | ESR1
|
| PvuII inside the human estrogen receptor gene.
|
| Castagnoli A, et al.
|
| Nucleic Acids Res 15 : 866. 1987
|
| 115 | ESR1
|
| Localization of the human oestrogen receptor gene to chromosome 6q24->q27 by in situ hybridization.
|
| Gosden JR, et al.
|
| Cytogenet Cell Genet 43 : 218-220. 1986
|
| 116 | ESR1
|
| Cloning of the human estrogen receptor cDNA.
|
| Walter P, Green S, Greene G, Krust A, Bornert JM, Jeltsch JM, Staub A, Jensen E, Scrace G, Waterfield M, et al.
|
| Proc Natl Acad Sci U S A 82 : 7889-7893. 1985
|