| 1 | ERRFI1, WEE1
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| The Tumor Suppressor MIG6 Controls Mitotic Progression and the G2/M DNA Damage Checkpoint by Stabilizing the WEE1 Kinase.
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| Sasaki M, Terabayashi T, Weiss SM, Ferby I.
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| Cell Rep 24(5):1278-1289. doi: 10.1016/j.celrep.2018.06.064.
2018
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| 2 | ERRFI1
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| Differential roles of ERRFI1 in EGFR and AKT pathway regulation affect cancer proliferation.
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| Cairns J, Fridley BL, Jenkins GD, Zhuang Y, Yu J, Wang L.
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| EMBO Rep 19(3). pii: e44767. doi: 10.15252/embr.201744767. Epub 2018 Jan 15.
2018
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| 3 | ABL1, ERRFI1
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| Nuclear Gene 33/Mig6 regulates the DNA damage response through an ATM serine/threonine kinase-dependent mechanism.
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| Li C, Park S, Zhang X, Eisenberg LM, Zhao H, Darzynkiewicz Z, Xu D.
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| J Biol Chem 292(40):16746-16759. doi: 10.1074/jbc.M117.803338. Epub 2017 Aug 25.
2017
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| 4 | ERRFI1
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| Mig-6 is down-regulated in HCC and inhibits the proliferation of HCC cells via the P-ERK/Cyclin D1 pathway.
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| Li Z, Qu L, Luo W, Tian Y, Zhai H, Xu K, Zhong H.
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| Exp Mol Pathol 102(3):492-499. doi: 10.1016/j.yexmp.2017.05.004. Epub 2017 May 12.
2017
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| 5 | CDC42, ERRFI1
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| Inhibition of Cdc42 is essential for Mig-6 suppression of cell migration induced by EGF.
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| Jiang X, Niu M, Chen D, Chen J, Cao Y, Li X, Ying H, Bergholz J, Zhang Y, Xiao ZX.
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| Oncotarget 7(31):49180-49193. doi: 10.18632/oncotarget.10205.
2016
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| 6 | ERRFI1
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| Role of Mig-6 in hepatic glucose metabolism.
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| Yoo JY, Kim TH, Kong S, Lee JH, Choi W, Kim KS, Kim HJ, Jeong JW, Ku BJ.
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| J Diabetes 8(1):86-97. doi: 10.1111/1753-0407.12261. Epub 2015 Mar 24.
2016
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| 7 | DNAJB1, ERRFI1
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| DNAJB1 negatively regulates MIG6 to promote epidermal growth factor receptor signaling.
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| Park SY, Choi HK, Seo JS, Yoo JY, Jeong JW, Choi Y, Choi KC, Yoon HG.
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| Biochim Biophys Acta 1853(10 Pt A):2722-30. doi: 10.1016/j.bbamcr.2015.07.024. Epub 2015 Aug 1.
2015
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| 8 | ERRFI1
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| Mig-6 regulates endometrial genes involved in cell cycle and progesterone signaling.
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| Yoo JY, Kim TH, Lee JH, Dunwoodie SL, Ku BJ, Jeong JW.
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| Biochem Biophys Res Commun 462(4):409-14. doi: 10.1016/j.bbrc.2015.04.146. Epub 2015 May 12.
2015
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| 9 | ERRFI1
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| Mig-6 suppresses endometrial cancer associated with Pten deficiency and ERK activation.
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| Kim TH, Yoo JY, Kim HI, Gilbert J, Ku BJ, Li J, Mills GB, Broaddus RR, Lydon JP, Lim JM, Yoon HG, Jeong JW.
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| Cancer Res 74(24):7371-82. doi: 10.1158/0008-5472.CAN-14-0794. Epub 2014 Nov 6.
2014
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| 10 | ERRFI1
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| Mig-6 participates in the regulation of cell senescence and retinoblastoma protein phosphorylation.
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| Milewska M, Kolch W.
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| Cell Signal 26(9):1870-7. doi: 10.1016/j.cellsig.2014.05.003. Epub 2014 May 9.
2014
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| 11 | ERRFI1, SPRY2
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| Regulation of EGFR trafficking and cell signaling by Sprouty2 and MIG6 in lung cancer cells.
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| Walsh AM, Lazzara MJ.
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| J Cell Sci 126(Pt 19):4339-48. doi: 10.1242/jcs.123208. Epub 2013 Jul 18.
2013
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| 12 | ERRFI1
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| The mitogen-inducible gene-6 is involved in regulation of cellular senescence in normal diploid fibroblasts.
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| Xie B, Zhao L, Chen H, Jin B, Mao Z, Yao Z.
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| Biol Cell 105(10):488-99. doi: 10.1111/boc.201200052. Epub 2013 Jul 24.
2013
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| 13 | ERRFI1
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| Mitogen-inducible gene 6 triggers apoptosis and exacerbates ER stress-induced β-cell death.
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| Chen YC, Colvin ES, Maier BF, Mirmira RG, Fueger PT.
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| Mol Endocrinol 27(1):162-71. doi: 10.1210/me.2012-1174. Epub 2012 Nov 30.
2013
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| 14 | CHEK1, ERRFI1
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| Chk1 phosphorylates the tumour suppressor Mig-6, regulating the activation of EGF signalling.
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| Liu N, Matsumoto M, Kitagawa K, Kotake Y, Suzuki S, Shirasawa S, Nakayama KI, Nakanishi M, Niida H, Kitagawa M.
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| EMBO J 31(10):2365-77. doi: 10.1038/emboj.2012.88. Epub 2012 Apr 13.
2012
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| 15 | ERRFI1
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| Mitogen-inducible gene-6 is a multifunctional adaptor protein with tumor suppressor-like activity in papillary thyroid cancer.
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| Lin CI, Du J, Shen WT, Whang EE, Donner DB, Griff N, He F, Moore FD Jr, Clark OH, Ruan DT.
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| J Clin Endocrinol Metab 96(3):E554-65. doi: 10.1210/jc.2010-1800. Epub 2010 Dec 29.
2011
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| 16 | EGFR, ERRFI1, STX8
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| Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
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| Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, Paik JH, Segatto O, Brennan C, Elferink LA, Wang YA, Chin L, DePinho RA.
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| Proc Natl Acad Sci U S A. 107(15):6912-7. 2010
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| 17 | ERRFI1
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| Mig-6 modulates uterine steroid hormone responsiveness and exhibits altered expression in endometrial disease.
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| Jeong JW, Lee HS, Lee KY, White LD, Broaddus RR, Zhang YW, Vande Woude GF, Giudice LC, Young SL, Lessey BA, Tsai SY, Lydon JP, DeMayo FJ.
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| Proc Natl Acad Sci U S A 106(21):8677-82. Epub 2009 May 13.
2009
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| 18 | ERRFI1
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| Mig-6, signal transduction, stress response and cancer.
|
| Zhang YW, Vande Woude GF.
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| Cell Cycle 6(5):507-13. Epub 2007 Mar 31. Review.
2007
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| 19 | ERRFI1
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| Evidence that MIG-6 is a tumor-suppressor gene.
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| Zhang YW, Staal B, Su Y, Swiatek P, Zhao P, Cao B, Resau J, Sigler R, Bronson R, Vande Woude GF.
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| Oncogene 26(2):269-76. Epub 2006 Jul 3.
2007
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| 20 | ERRFI1
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| Inhibition of the EGF receptor by binding of MIG6 to an activating kinase domain interface.
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| Zhang X, Pickin KA, Bose R, Jura N, Cole PA, Kuriyan J.
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| Nature 450(7170):741-4.
2007
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| 21 | ERRFI1
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| Mig6 is a negative regulator of EGF receptor-mediated skin morphogenesis and tumor formation.
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| Ferby I, Reschke M, Kudlacek O, Knyazev P, Pante G, Amann K, Sommergruber W, Kraut N, Ullrich A, Fassler R, Klein R.
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| Nat Med 12(5):568-73. Epub 2006 Apr 30. 2006
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| 22 | ERRFI1
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| Gene 33 is an endogenous inhibitor of epidermal growth factor (EGF) receptor signaling and mediates dexamethasone-induced suppression of EGF function.
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| Xu D, Makkinje A, Kyriakis JM.
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| J Biol Chem 280(4):2924-33. Epub 2004 Nov 19. 2005
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| 23 | ERRFI1
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| Loss of RALT/MIG-6 expression in ERBB2-amplified breast carcinomas enhances ErbB-2 oncogenic potency and favors resistance to Herceptin.
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| Anastasi S, Sala G, Huiping C, Caprini E, Russo G, Iacovelli S, Lucini F, Ingvarsson S, Segatto O.
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| Oncogene 24(28):4540-8. 2005
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| 24 | ERRFI1
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| Increased MIG-6 mRNA transcripts in osteoarthritic cartilage.
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| Mateescu RG, Todhunter RJ, Lust G, Burton-Wurster N.
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| Biochem Biophys Res Commun 332(2):482-6. 2005
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| 25 | ERRFI1
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| Feedback inhibition by RALT controls signal output by the ErbB network.
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| Anastasi S, Fiorentino L, Fiorini M, Fraioli R, Sala G, Castellani L, Alema S, Alimandi M, Segatto O.
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| Oncogene 22(27):4221-34. 2003
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| 26 | ERRFI1
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| A novel mechanism of nuclear factor kappaB activation through the binding between inhibitor of nuclear factor-kappaBalpha and the processed NH(2)-terminal region of Mig-6.
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| Tsunoda T, Inokuchi J, Baba I, Okumura K, Naito S, Sasazuki T, Shirasawa S.
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| Cancer Res 62(20):5668-71. 2002
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| 27 | ERRFI1
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| Mitogen-inducible gene 6 (MIG-6), adipophilin and tuftelin are inducible by hypoxia.
|
| Saarikoski ST, Rivera SP, Hankinson O.
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| FEBS Lett 530(1-3):186-90. 2002
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| 28 | ERRFI1
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| Inhibition of ErbB-2 mitogenic and transforming activity by RALT, a mitogen-induced signal transducer which binds to the ErbB-2 kinase domain.
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| Fiorentino L, Pertica C, Fiorini M, Talora C, Crescenzi M, Castellani L, Alema S, Benedetti P, Segatto O.
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| Mol Cell Biol 20(20):7735-50. 2000
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| 29 | ERRFI1
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| Identification of a novel mitogen-inducible gene (mig-6): regulation during G1 progression and differentiation.
|
| Wick M, Burger C, Funk M, Muller R.
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| Exp Cell Res 219(2):527-35. 1995
|