| 1 | ERLIN1, ERLIN2, SCAP, SREBF1, SREBF2
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| Erlins restrict SREBP activation in the ER and regulate cellular cholesterol homeostasis.
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| Huber MD, Vesely PW, Datta K, Gerace L.
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| J Cell Biol 203(3):427-36. doi: 10.1083/jcb.201305076.
2013
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| 2 | ERLIN2, SPG18
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| A novel splice site mutation in ERLIN2 causes hereditary spastic paraplegia in a Saudi family.
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| Wakil SM, Bohlega S, Hagos S, Baz B, Al Dossari H, Ramzan K, Al-Hassnan ZN.
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| Eur J Med Genet 56(1):43-5. doi: 10.1016/j.ejmg.2012.10.003. Epub 2012 Oct 18.
2013
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| 3 | ERLIN2
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| Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.
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| Teranishi Y, Hur JY, Gu GJ, Kihara T, Ishikawa T, Nishimura T, Winblad B, Behbahani H, Kamali-Moghaddam M, Frykman S, Tjernberg LO.
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| Biochem Biophys Res Commun 424(3):476-81. doi: 10.1016/j.bbrc.2012.06.137. Epub 2012 Jul 4.
2012
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| 4 | ERLIN2
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| Endoplasmic reticulum factor ERLIN2 regulates cytosolic lipid content in cancer cells.
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| Wang G, Zhang X, Lee JS, Wang X, Yang ZQ, Zhang K.
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| Biochem J 446(3):415-25. doi: 10.1042/BJ20112050.
2012
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| 5 | ERLIN2, PLSJ2
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| Loss of ERLIN2 function leads to juvenile primary lateral sclerosis.
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| Al-Saif A, Bohlega S, Al-Mohanna F.
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| Ann Neurol 72(4):510-6. doi: 10.1002/ana.23641.
2012
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| 6 | ERLIN2
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| Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.
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| Teranishi Y, Hur JY, Gu GJ, Kihara T, Ishikawa T, Nishimura T, Winblad B, Behbahani H, Kamali-Moghaddam M, Frykman S, Tjernberg LO.
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| Biochem Biophys Res Commun 424(3):476-81. doi: 10.1016/j.bbrc.2012.06.137. Epub 2012 Jul 4.
2012
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| 7 | ERLIN2
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| ERLIN2 promotes breast cancer cell survival by modulating endoplasmic reticulum stress pathways.
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| Wang G, Liu G, Wang X, Sethi S, Ali-Fehmi R, Abrams J, Zheng Z, Zhang K, Ethier S, Yang ZQ.
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| BMC Cancer 12:225. doi: 10.1186/1471-2407-12-225.
2012
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| 8 | ERLIN2, IDMDC
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| A frameshift mutation of ERLIN2 in recessive intellectual disability, motor dysfunction and multiple joint contractures.
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| Yıldırım Y, Orhan EK, Iseri SA, Serdaroglu-Oflazer P, Kara B, Solakoğlu S, Tolun A.
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| Hum Mol Genet 20(10):1886-92. Epub 2011 Feb 17.
2011
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| 9 | ERLIN2
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| A nullimorphic ERLIN2 mutation defines a complicated hereditary spastic paraplegia locus (SPG18).
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| Alazami AM, Adly N, Al Dhalaan H, Alkuraya FS.
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| Neurogenetics. 2011
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| 10 | AMFR, ERLIN2, TMUB1
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| Membrane-associated ubiquitin ligase complex containing gp78 mediates sterol-accelerated degradation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase.
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| Jo Y, Sguigna PV, DeBose-Boyd RA.
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| J Biol Chem 286(17):15022-31. doi: 10.1074/jbc.M110.211326. Epub 2011 Feb 22.
2011
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| 11 | ERLIN1, ERLIN2
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| Clustered hydrophobic amino acids in amphipathic helices mediate erlin1/2 complex assembly.
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| Pednekar D, Wang Y, Fedotova TV, Wojcikiewicz RJ.
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| Biochem Biophys Res Commun 415(1):135-40. doi: 10.1016/j.bbrc.2011.10.032. Epub 2011 Oct 12.
2011
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| 12 | BRF2, ERLIN2, GPR124, PROSC, ZNF703
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| High-resolution analysis of genomic alteration on chromosome arm 8p in urothelial carcinoma.
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| Williams SV, Platt FM, Hurst CD, Aveyard JS, Taylor CF, Pole JC, Garcia MJ, Knowles MA.
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| Genes Chromosomes Cancer 49(7):642-59. doi: 10.1002/gcc.20775.
2010
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| 13 | ERLIN2
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| An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors.
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| Pearce MM, Wormer DB, Wilkens S, Wojcikiewicz RJ.
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| J Biol Chem. 284(16):10433-45. 2009
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| 14 | ERLIN1, ERLIN2
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| SPFH1 and SPFH2 mediate the ubiquitination and degradation of inositol 1,4,5-trisphosphate receptors in muscarinic receptor-expressing HeLa cells.
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| Wang Y, Pearce MM, Sliter DA, Olzmann JA, Christianson JC, Kopito RR, Boeckmann S, Gagen C, Leichner GS, Roitelman J, Wojcikiewicz RJ.
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| Biochim Biophys Acta 1793(11):1710-8. doi: 10.1016/j.bbamcr.2009.09.004. Epub 2009 Sep 12.
2009
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| 15 | ERLIN1, ERLIN2
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| An endoplasmic reticulum (ER) membrane complex composed of SPFH1 and SPFH2 mediates the ER-associated degradation of inositol 1,4,5-trisphosphate receptors.
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| Pearce MM, Wormer DB, Wilkens S, Wojcikiewicz RJ.
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| J Biol Chem 284(16):10433-45. doi: 10.1074/jbc.M809801200. Epub 2009 Feb 24.
2009
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| 16 | ERLIN2
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| SPFH2 mediates the endoplasmic reticulum-associated degradation of inositol 1,4,5-trisphosphate receptors and other substrates in mammalian cells.
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| Pearce MM, Wang Y, Kelley GG, Wojcikiewicz RJ.
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| J Biol Chem. 282(28):20104-15. 2007
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| 17 | ERLIN2
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| Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER.
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| Browman DT, Resek ME, Zajchowski LD, Robbins SM.
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| J Cell Sci. 119(Pt 15):3149-60. 2006
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| 18 | ERLIN1, ERLIN2
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| Erlin-1 and erlin-2 are novel members of the prohibitin family of proteins that define lipid-raft-like domains of the ER.
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| Browman DT, Resek ME, Zajchowski LD, Robbins SM.
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| J Cell Sci 119(Pt 15):3149-60. Epub 2006 Jul 11.
2006
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| 19 | ERLIN2
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| A 1 Mb minimal amplicon at 8p11-12 in breast cancer identifies new candidate oncogenes.
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| Garcia MJ, Pole JC, Chin SF, Teschendorff A, Naderi A, Ozdag H, Vias M, Kranjac T, Subkhankulova T, Paish C, Ellis I, Brenton JD, Edwards PA, Caldas C.
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| Oncogene 24(33):5235-45. 2005
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| 20 | ERLIN2
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| Cloning and characterization of a novel gene (C8orf2), a human representative of a novel gene family with homology to C. elegans C42.C1.9.
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| Ikegawa S, Isomura M, Koshizuka Y, Nakamura Y.
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| Cytogenet Cell Genet 85(3-4):227-31. 1999
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