Citations for
1ERG, TMPRSS2
Retention of Interstitial Genes between TMPRSS2 and ERG Is Associated with Low-Risk Prostate Cancer.
Murphy SJ, Kosari F, Karnes RJ, Nasir A, Johnson SH, Gaitatzes AG, Smadbeck JB, Rangel LJ, Vasmatzis G, Cheville JC.
Cancer Res 77(22):6157-6167. doi: 10.1158/0008-5472.CAN-17-0529. Epub 2017 Nov 10. 2017
2CNOT2, ERG, RBPMS
The transcription factor ERG recruits CCR4-NOT to control mRNA decay and mitotic progression.
Rambout X, Detiffe C, Bruyr J, Mariavelle E, Cherkaoui M, Brohée S, Demoitié P, Lebrun M, Soin R, Lesage B, Guedri K, Beullens M, Bollen M, Farazi TA, Kettmann R, Struman I, Hill DE, Vidal M, Kruys V, Simonis N, Twizere JC, Dequiedt F.
Nat Struct Mol Biol 23(7):663-72. doi: 10.1038/nsmb.3243. 2016
3AMLACR, ERG
High alpha-methylacyl-CoA racemase (AMACR) is associated with ERG expression and with adverse clinical outcome in patients with localized prostate cancer.
Box A, Alshalalfa M, Hegazy SA, Donnelly B, Bismar TA.
Tumour Biol 37(9):12287-12299. Epub 2016 Jun 7. 2016
4ERG, TMPRSS2
Inflammation-Induced Oxidative Stress Mediates Gene Fusion Formation in Prostate Cancer.
Mani RS, Amin MA, Li X, Kalyana-Sundaram S, Veeneman BA, Wang L, Ghosh A, Aslam A, Ramanand SG, Rabquer BJ, Kimura W, Tran M, Cao X, Roychowdhury S, Dhanasekaran SM, Palanisamy N, Sadek HA, Kapur P, Koch AE, Chinnaiyan AM.
Cell Rep 17(10):2620-2631. doi: 10.1016/j.celrep.2016.11.019. 2016
5ERG, SPOP
SPOP Promotes Ubiquitination and Degradation of the ERG Oncoprotein to Suppress Prostate Cancer Progression.
Gan W, Dai X, Lunardi A, Li Z, Inuzuka H, Liu P, Varmeh S, Zhang J, Cheng L, Sun Y, Asara JM, Beck AH, Huang J, Pandolfi PP, Wei W.
Mol Cell 59(6):917-30. doi: 10.1016/j.molcel.2015.07.026. Epub 2015 Sep 3. 2015
6ERG, TMPRSS2
TMPRSS2:ERG gene fusion predicts subsequent detection of prostate cancer in patients with high-grade prostatic intraepithelial neoplasia.
Park K, Dalton JT, Narayanan R, Barbieri CE, Hancock ML, Bostwick DG, Steiner MS, Rubin MA.
J Clin Oncol 32(3):206-11. doi: 10.1200/JCO.2013.49.8386. Epub 2013 Dec 2. 2014
7ERG, LEF1
ERG is a critical regulator of Wnt/LEF1 signaling in prostate cancer.
Wu L, Zhao JC, Kim J, Jin HJ, Wang CY, Yu J.
Cancer Res 73(19):6068-79. doi: 10.1158/0008-5472.CAN-13-0882. Epub 2013 Aug 1. 2013
8ERG
Structural and dynamic studies of the transcription factor ERG reveal DNA binding is allosterically autoinhibited.
Regan MC, Horanyi PS, Pryor EE Jr, Sarver JL, Cafiso DS, Bushweller JH.
Proc Natl Acad Sci U S A 110(33):13374-9. doi: 10.1073/pnas.1301726110. Epub 2013 Jul 29. 2013
9AR, ERG, SOX9
ERG induces androgen receptor-mediated regulation of SOX9 in prostate cancer.
Cai C, Wang H, He HH, Chen S, He L, Ma F, Mucci L, Wang Q, Fiore C, Sowalsky AG, Loda M, Liu XS, Brown M, Balk SP, Yuan X.
J Clin Invest 123(3):1109-22. doi: 10.1172/JCI66666. Epub 2013 Feb 15. 2013
10ERG, TDRD1
Identification of TDRD1 as a direct target gene of ERG in primary prostate cancer.
Boormans JL, Korsten H, Ziel-van der Made AJ, van Leenders GJ, de Vos CV, Jenster G, Trapman J.
Int J Cancer 133(2):335-45. doi: 10.1002/ijc.28025. Epub 2013 Feb 12. 2013
11ERG
ERG transcriptional networks in primary acute leukemia cells implicate a role for ERG in deregulated kinase signaling.
Bock J, Mochmann LH, Schlee C, Farhadi-Sartangi N, Göllner S, Müller-Tidow C, Baldus CD.
PLoS One 8(1):e52872. doi: 10.1371/journal.pone.0052872. Epub 2013 Jan 3. 2013
12ERG, SLC45A3
Loss of SLC45A3 protein (prostein) expression in prostate cancer is associated with SLC45A3-ERG gene rearrangement and an unfavorable clinical course.
Perner S, Rupp NJ, Braun M, Rubin MA, Moch H, Dietel M, Wernert N, Jung K, Stephan C, Kristiansen G.
Int J Cancer 132(4):807-12. doi: 10.1002/ijc.27733. Epub 2012 Aug 30. 2013
13ERG, RELA
The transcription factor Erg controls endothelial cell quiescence by repressing activity of nuclear factor (NF)-κB p65.
Dryden NH, Sperone A, Martin-Almedina S, Hannah RL, Birdsey GM, Khan ST, Layhadi JA, Mason JC, Haskard DO, Göttgens B, Randi AM.
J Biol Chem 287(15):12331-42. doi: 10.1074/jbc.M112.346791. Epub 2012 Feb 15. 2012
14CLDN5, ERG
ETS-related gene (ERG) controls endothelial cell permeability via transcriptional regulation of the claudin 5 (CLDN5) gene.
Yuan L, Le Bras A, Sacharidou A, Itagaki K, Zhan Y, Kondo M, Carman CV, Davis GE, Aird WC, Oettgen P.
J Biol Chem 287(9):6582-91. doi: 10.1074/jbc.M111.300236. Epub 2012 Jan 10. 2012
15ERG, WNT11
Genome-wide screen reveals WNT11, a non-canonical WNT gene, as a direct target of ETS transcription factor ERG.
Mochmann LH, Bock J, Ortiz-Tánchez J, Schlee C, Bohne A, Neumann K, Hofmann WK, Thiel E, Baldus CD.
Oncogene 30(17):2044-56. Epub 2011 Jan 17. 2011
16ERG
ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification.
Taoudi S, Bee T, Hilton A, Knezevic K, Scott J, Willson TA, Collin C, Thomas T, Voss AK, Kile BT, Alexander WS, Pimanda JE, Hilton DJ.
Genes Dev 25(3):251-62. Epub 2011 Jan 18. 2011
17ERG
ERG promotes T-acute lymphoblastic leukemia and is transcriptionally regulated in leukemic cells by a stem cell enhancer.
Thoms JA, Birger Y, Foster S, Knezevic K, Kirschenbaum Y, Chandrakanthan V, Jonquieres G, Spensberger D, Wong JW, Oram SH, Kinston SJ, Groner Y, Lock R, MacKenzie KL, Göttgens B, Izraeli S, Pimanda JE.
Blood 117(26):7079-89. Epub 2011 May 2. 2011
18ERG, TMPRSS2
TMPRSS2-ERG Gene Fusion and Clinicopathologic Characteristics of Korean Prostate Cancer Patients.
Lee K, Chae JY, Kwak C, Ku JH, Moon KC.
Urology rology. 2010 Aug 26. [Epub ahead of print]PMID: 20800881 2010
19ERG, TMPRSS2
ERG rearrangement is present in a subset of transition zone prostatic tumors.
Falzarano SM, Navas M, Simmerman K, Klein EA, Rubin MA, Zhou M, Magi-Galluzzi C.
Mod Pathol od Pathol. 2010 Aug 6. [Epub ahead of print]PMID: 20693982 2010
20AKT, ERG, PTEN, TMPRSS2
Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis.
King JC, Xu J, Wongvipat J, Hieronymus H, Carver BS, Leung DH, Taylor BS, Sander C, Cardiff RD, Couto SS, Gerald WL, Sawyers CL.
Nat Genet 41(5):524-6. Epub 2009 Apr 26. 2009
21AKT, ERG, PTEN, TMPRSS2, TMPRSS6
Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate.
Carver BS, Tran J, Gopalan A, Chen Z, Shaikh S, Carracedo A, Alimonti A, Nardella C, Varmeh S, Scardino PT, Cordon-Cardo C, Gerald W, Pandolfi PP.
Nat Genet 41(5):619-24. Epub 2009 Apr 26. 2009
22ERG
Distinct genomic aberrations associated with ERG rearranged prostate cancer.
Demichelis F, Setlur SR, Beroukhim R, Perner S, Korbel JO, Lafargue CJ, Pflueger D, Pina C, Hofer MD, Sboner A, Svensson MA, Rickman DS, Urban A, Snyder M, Meyerson M, Lee C, Gerstein MB, Kuefer R, Rubin MA.
Genes Chromosomes Cancer 48(4):366-80. 2009
23ERG, TMPRSS2
Genome-wide linkage analysis of TMPRSS2-ERG fusion in familial prostate cancer.
Hofer MD, Kuefer R, Maier C, Herkommer K, Perner S, Demichelis F, Paiss T, Vogel W, Rubin MA, Hoegel J.
Cancer Res 69(2):640-6. 2009
24ERG, NDRG1
N-myc downstream regulated gene 1 (NDRG1) is fused to ERG in prostate cancer.
Pflueger D, Rickman DS, Sboner A, Perner S, LaFargue CJ, Svensson MA, Moss BJ, Kitabayashi N, Pan Y, de la Taille A, Kuefer R, Tewari AK, Demichelis F, Chee MS, Gerstein MB, Rubin MA.
Neoplasia 11(8):804-11. 2009
25ERG
Transcription factor Erg regulates angiogenesis and endothelial apoptosis through VE-cadherin.
Birdsey GM, Dryden NH, Amsellem V, Gebhardt F, Sahnan K, Haskard DO, Dejana E, Mason JC, Randi AM.
Blood 111(7):3498-506. Epub 2008 Jan 14. 2008
26ERG, TMPRSS2
Detection of the TMPRSS2-ETS fusion gene in prostate carcinomas: retrospective analysis of 55 formalin-fixed and paraffin-embedded samples with clinical data.
Rouzier C, Haudebourg J, Carpentier X, Valério L, Amiel J, Michiels JF, Pedeutour F.
Cancer Genet Cytogenet 183(1):21-7.PMID: 18474293 2008
27ERG
TMPRSS2-ERG fusion, a common genomic alteration in prostate cancer activates C-MYC and abrogates prostate epithelial differentiation.
Sun C, Dobi A, Mohamed A, Li H, Thangapazham RL, Furusato B, Shaheduzzaman S, Tan SH, Vaidyanathan G, Whitman E, Hawksworth DJ, Chen Y, Nau M, Patel V, Vahey M, Gutkind JS, Sreenath T, Petrovics G, Sesterhenn IA, McLeod DG, Srivastava S.
Oncogene 27(40):5348-53. Epub 2008 Jun 9. 2008
28TMPRSS2, ERG
Multiple genomic alterations on 21q22 predict various TMPRSS2/ERG fusion transcripts in human prostate cancers.
Liu W, Ewing CM, Chang BL, Li T, Sun J, Turner AR, Dimitrov L, Zhu Y, Sun J, Kim JW, Zheng SL, Isaacs WB, Xu J.
Genes Chromosomes Cancer 46(11):972-80. 2007
29ERG, TMPRSS2
Diversity of TMPRSS2-ERG fusion transcripts in the human prostate.
Clark J, Merson S, Jhavar S, Flohr P, Edwards S, Foster CS, Eeles R, Martin FL, Phillips DH, Crundwell M, Christmas T, Thompson A, Fisher C, Kovacs G, Cooper CS.
Oncogene 26(18):2667-73. Epub 2006 Oct 16. 2007
30ERG, TMPRSS2
TMPRSS2-ERG fusion heterogeneity in multifocal prostate cancer: clinical and biologic implications.
Barry M, Perner S, Demichelis F, Rubin MA.
Urology 70(4):630-3. 2007
31ELF4, ERG
ELF4 is fused to ERG in a case of acute myeloid leukemia with a t(X;21)(q25-26;q22).
Moore SD, Offor O, Ferry JA, Amrein PC, Morton CC, Dal Cin P.
Leuk Res 30(8):1037-42. Epub 2005 Nov 21. 2006
32ERG, ETV1, TMPRSS2
Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.
Tomlins SA, Rhodes DR, Perner S, Dhanasekaran SM, Mehra R, Sun XW, Varambally S, Cao X, Tchinda J, Kuefer R, Lee C, Montie JE, Shah RB, Pienta KJ, Rubin MA, Chinnaiyan AM.
Science 310(5748):644-8. 2005
33C21orf24, ERG, ETS2
Detailed mapping of the ERG-ETS2 interval of human chromosome 21 and comparison with the region of conserved synteny on mouse chromosome 16.
Owczarek CM, Portbury KJ, Hardy MP, O'Leary DA, Kudoh J, Shibuya K, Shimizu N, Kola I, Hertzog PJ.
Gene 324:65-77. 2004
34FUS, ERG
FUS/ERG gene fusions in Ewing's tumors.
Shing DC, McMullan DJ, Roberts P, Smith K, Chin SF, Nicholson J, Tillman RM, Ramani P, Cullinane C, Coleman N.
Cancer Res 63(15):4568-76. 2003
35ERG, SETDB1
Molecular cloning of ESET, a novel histone H3-specific methyltransferase that interacts with ERG transcription factor.
Yang L, Xia L, Wu DY, Wang H, Chansky HA, Schubach WH, Hickstein DD, Zhang Y.
Oncogene 21(1):148-52. 2002
36ID2, EWSR1, FLI1, ERG
The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
Nishimori H, Sasaki Y, Yoshida K, Irifune H, Zembutsu H, Tanaka T, Aoyama T, Hosaka T, Kawaguchi S, Wada T, Hata J, Toguchida J, Nakamura Y, Tokino T.
Oncogene 21(54):8302-9. 2002
37ERG, EWSR1
Fine-mapping of cytogenetically undetectable EWS/ERG fusions on DNA fibers of Ewing tumors.
Hattinger CM, Rumpler S, Kovar H, Ambros PF.
Cytogenet Cell Genet 93(1-2):29-35. 2001
38ERG
Selective expression of erg isoforms in human endothelial cells.
Hewett PW, Nishi K, Daft EL, Clifford Murray J.
Int J Biochem Cell Biol 33(4):347-55. 2001
39CHAF1B, CBR1, ERG, DSCR4, DSCR8
Transcriptional map of the 2.5-Mb CBR-ERG region of chromosome 21 involved in Down syndrome.
Dahmane N, Ghezala GA, Gosset P, Chamoun Z, Dufresne-Zacharia MC, Lopes C, Rabatel N, Gassanova-Maugenre S, Chettouh Z, Abramowski V, Fayet E, Yaspo ML, Korn B, Blouin JL, Lehrach H, Poutska A, Antonarakis SE, Sinet PM, Creau N, Delabar JM.
Genomics 48(1):12-23. 1998
40ERG, EWSR1, EWSR1
EWS-ERG fusion transcript produced by chromosomal insertion in a Ewing sarcoma.
Kaneko Y, et al.
Genes Chromosomes Cancer 18 : 228-231. 1997
41ERG, FUS, AMLT1
Consistent detection of TLS/FUS-ERG chimeric transcripts in acute myeloid leukemia with t(16;21)(p11;q22) and identification of a novel transcript.
Kong XT, Ida K, Ichikawa H, Shimizu K, Ohki M, Maseki N, Kaneko Y, Sako M, Kobayashi Y, Tojou A, Miura I, Kakuda H, Funabiki T, Horibe K, Hamaguchi H, Akiyama Y, Bessho F, Yanagisawa M, Hayashi Y.
Blood 90(3):1192-9. 1997
42DDIT3, ERG, EWSR1, FUS
Characteristic sequence motifs at the breakpoints of the hybrid genes FUS/CHOP, EWS/CHOP and FUS/ERG in myxoid liposarcoma and acute myeloid leukemia.
Panagopoulos I, Lassen C, Isaksson M, Mitelman F, Mandahl N, Aman P.
Oncogene 15(11):1357-62. 1997
43RCAN1, ERG, SIM2
A 1.6-Mb P1-based physical map of the Down syndrome region on chromosome21.
Ohira M, et al.
Genomics 33 : 65-74. 1996
44DDIT3, ERG, FUS
Two distinct FUS breakpoint clusters in myxoid liposarcoma and acute myeloid leukemia with the translocations t(12;16) and t(16;21).
Panagopoulos I, et al.
oncogene 11 : 1133-1137 1995
45ERG, EWSR1, EWSR1, FLI1
A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS-family transcription factor, ERG.
Sorensen PHB, et al.
Nat Genet 6 : 146-151. 1994
46FUS, ERG
TLS/FUS fusion domain of TLS/FUS-erg chimeric protein resulting from the t(16;21) chromosomal translocation in human myeloid leukemia functions as a transcriptional activation domain.
Prasad DDK, et al.
Oncogene 9 : 3717-3729. 1994
47FUS, ERG
Fusion of the FUS gene with ERG in acute myeloid leukemia with t(16;21)(p11;q22).
Panagopoulos I, et al.
Genes Chromosomes Cancer 11 : 256-262. 1994
48ERG
An ets-related gene, ERG, is rearranged in human myeloid leukemia with t(16;21) chromosomal translocation.
Shimizu K, et al.
Proc Natl Acad Sci U S A 90 : 10280-10284. 1993
49ERG
Chromosomal localization of the erg cellular proto-oncogene.
Modi WS, et al.
(HGM10) Cytogenet Cell Genet 51 : 1046. 1989
50ERG
The human erg gene maps to chromosome 21, band q22 : relationship to the 8;21 translocation of acute myelogenous leukemia.
Rao VN, et al.
Oncogene 3 : 497-500. 1988
51ETS2, ERG
The ETS genes on chromosome 21 are distal to the breakpoint of the acute myelogenous leukemia translocation (8;21).
Sacchi N, et al.
Genomics 3 : 110-116. 1988
52ERG
Erg, a human ets-related gene on chromosome 21: Alternative splicing polyadenylation and translation.
Rao VN, et al.
Science 237 : 635-639. 1987