1 | ERBB2, ERBB3
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| CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.
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| Dahlhoff M, Gaborit N, Bultmann S, Leonhardt H, Yarden Y, Schneider MR.
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| FEBS J 284(19):3339-3349. doi: 10.1111/febs.14196. Epub 2017 Sep 14.
2017
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2 | APIP, ERBB3
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| APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.
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| Hong SH, Lee WJ, Kim YD, Kim H, Jeon YJ, Lim B, Cho DH, Heo WD, Yang DH, Kim CY, Yang HK, Yang JK, Jung YK.
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| Oncotarget 7(16):21601-17. doi: 10.18632/oncotarget.7802.
2016
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3 | CADM1, ERBB3, ERBB4
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| Necl-2/CADM1 interacts with ErbB4 and regulates its activity in GABAergic neurons.
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| Yamada A, Inoue E, Deguchi-Tawarada M, Matsui C, Togawa A, Nakatani T, Ono Y, Takai Y.
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| Mol Cell Neurosci 56C:234-243. doi: 10.1016/j.mcn.2013.06.003. [Epub ahead of print]
2013
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4 | ERBB3
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| The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium.
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| Balko JM, Miller TW, Morrison MM, Hutchinson K, Young C, Rinehart C, Sánchez V, Jee D, Polyak K, Prat A, Perou CM, Arteaga CL, Cook RS.
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| Proc Natl Acad Sci U S A 109(1):221-6. doi: 10.1073/pnas.1115802109. Epub 2011 Dec 16.
2012
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5 | ERBB2, ERBB3
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| Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling.
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| Zhang Q, Park E, Kani K, Landgraf R.
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| Proc Natl Acad Sci U S A 109(33):13237-42. doi: 10.1073/pnas.1200105109. Epub 2012 Jun 25.
2012
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6 | ERBB2, ERBB3
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| Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase.
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| Garrett JT, Olivares MG, Rinehart C, Granja-Ingram ND, Sánchez V, Chakrabarty A, Dave B, Cook RS, Pao W, McKinely E, Manning HC, Chang J, Arteaga CL.
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| Proc Natl Acad Sci U S A 108(12):5021-6. Epub 2011 Mar 8.
2011
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7 | ERBB3
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| A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination.
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| Adilakshmi T, Ness-Myers J, Madrid-Aliste C, Fiser A, Tapinos N.
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| J Neurosci. 31(13):5106-19. 2011
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8 | ERBB3
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| ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis.
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| Cook RS, Garrett JT, Sánchez V, Stanford JC, Young C, Chakrabarty A, Rinehart C, Zhang Y, Wu Y, Greenberger L, Horak ID, Arteaga CL.
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| Cancer Res 71(11):3941-51. Epub 2011 Apr 11.
2011
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9 | ERBB3, RNF41
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| Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
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| Ingalla EQ, Miller JK, Wald JH, Workman HC, Kaur RP, Yen L, Fry WH, Borowsky AD, Young LJ, Sweeney C, Carraway KL 3rd.
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| J Biol Chem 285(37):28691-7. Epub 2010 Jul 13.
2010
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10 | ERBB3, SOST
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| Sclerostin-erbB-3 interactions: modulation of erbB-3 activity by sclerostin.
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| Craig TA, Kumar R.
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| Biochem Biophys Res Commun 402(2):421-4. Epub 2010 Oct 14.
2010
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11 | ERBB3
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| NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation.
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| Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ.
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| Pigment Cell Melanoma Res 22(6):773-84. Epub 2009 Jul 30.PMID: 19659570 2009
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12 | ERBB3
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| Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3.
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| Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J.
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| Proc Natl Acad Sci U S A 106(51):21608-13. Epub 2009 Dec 9.PMID: 20007378 2009
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13 | ERBB3
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| The ERBB3 receptor in cancer and cancer gene therapy.
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| Sithanandam G, Anderson LM.
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| Cancer Gene Ther 15(7):413-48. Epub 2008 Apr 11. Review.
2008
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14 | ERBB3
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| High expression of HER3 is associated with a decreased survival in gastric cancer.
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| Hayashi M, Inokuchi M, Takagi Y, Yamada H, Kojima K, Kumagai J, Kawano T, Sugihara K.
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| Clin Cancer Res 14(23):7843-9.PMID: 19047113 2008
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15 | ERBB3
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| HER3 is a determinant for poor prognosis in melanoma.
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| Reschke M, Mihic-Probst D, van der Horst EH, Knyazev P, Wild PJ, Hutterer M, Meyer S, Dummer R, Moch H, Ullrich A.
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| Clin Cancer Res 14(16):5188-97.PMID: 18698037 2008
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16 | EGFR, ERBB2, ERBB3, ERBB4
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| N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.
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| Takahashi M, Yokoe S, Asahi M, Lee SH, Li W, Osumi D, Miyoshi E, Taniguchi N.
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| Biochim Biophys Acta 1780(3):520-4. Epub 2007 Nov 6.PMID: 18036567 2008
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17 | ERBB3,LCCS2
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| Lethal Congenital Contractural Syndrome Type 2 (LCCS2) Is Caused by a Mutation in ERBB3 (Her3), a Modulator of the Phosphatidylinositol-3-Kinase/Akt Pathway.
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| Narkis G, Ofir R, Manor E, Landau D, Elbedour K, Birk OS.
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| Am J Hum Genet 81(3):589-95. Epub 2007 Jul 24. 2007
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18 | EGFR, ERBB2, ERBB3, ERBB4
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| Characterization of a novel tripartite nuclear localization sequence in the EGFR family.
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| Hsu SC, Hung MC.
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| J Biol Chem 282(14):10432-40. Epub 2007 Feb 5. 2007
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19 | ERBB3
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| Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.
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| Addo-Yobo SO, Straessle J, Anwar A, Donson AM, Kleinschmidt-Demasters BK, Foreman NK.
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| J Neuropathol Exp Neurol 65(8):769-75. 2006
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20 | ERBB3
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| Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma.
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| van der Horst EH, Weber I, Ullrich A.
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| Int J Cancer. 113(5):689-98. 2004
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21 | NRG1, NRG2, NRG3, ERBB2, ERBB3, ERBB4, EGFR
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| Neuregulin promotes autophagic cell death of prostate cancer cells.
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| Tal-Or P, Di-Segni A, Lupowitz Z, Pinkas-Kramarski R.
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| Prostate 55(2):147-57. 2003
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22 | ERBB3
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| Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR.
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| Odintsova E, Voortman J, Gilbert E, Berditchevski F.
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| J Cell Sci. 116(Pt 22):4557-66. 2003
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23 | ERBB3
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| Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system.
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| Thaminy S, Auerbach D, Arnoldo A, Stagljar I.
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| Genome Res. 13(7):1744-53. 2003
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24 | ERBB3, RNF41
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| Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3.
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| Qiu XB, Goldberg AL.
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| Proc Natl Acad Sci U S A 99(23):14843-8. Epub 2002 Oct 31. Erratum in: Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17220..
2002
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25 | ERBB3
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| Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display.
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| Stortelers C, Souriau C, van Liempt E, van de Poll ML, van Zoelen EJ.
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| Biochemistry. 41(27):8732-41. 2002
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26 | ERBB3
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| An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells.
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| Grant SL, Hammacher A, Douglas AM, Goss GA, Mansfield RK, Heath JK, Begley CG.
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| Oncogene. 21(3):460-74. 2002
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27 | ERBB3
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| Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3.
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| Qiu XB, Goldberg AL.
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| Proc Natl Acad Sci U S A. 99(23):14843-8. 2002
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28 | ERBB3
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| Mapping a heparin binding site on ErbB-3 epidermal growth factor receptor.
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| Adar R, Yayon A.
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| Biochem Biophys Res Commun 283(1):1-5. 2001
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29 | ERBB3
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| Identification of a heregulin binding site in HER3 extracellular domain
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| Singer E, Landgraf R, Horan T, Slamon D, Eisenberg D.
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| J Biol Chem 276(47):44266-74. 2001
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30 | ERBB3
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| Neuregulin-induced association of Sos Ras exchange protein with HER2(erbB2)/HER3(erbB3) receptor complexes in Schwann cells through a specific Grb2-HER2(erbB2) interaction.
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| Goodearl A, Viehover A, Vartanian T.
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| Dev Neurosci. 23(1):25-30. 2001
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31 | ERBB3
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| Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulin.
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| Yoo JY, Wang XW, Rishi AK, Lessor T, Xia XM, Gustafson TA, Hamburger AW.
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| Br J Cancer. 82(3):683-90. 2000
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32 | ERBB3
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| Identification of an interaction between the angiotensin II receptor sub-type AT2 and the ErbB3 receptor, a member of the epidermal growth factor receptor family.
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| Knowle D, Ahmed S, Pulakat L.
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| Regul Pept. 87(1-3):73-82. 2000
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33 | ERBB3
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| Neuregulin induces the rapid association of focal adhesion kinase with the erbB2-erbB3 receptor complex in schwann cells.
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| Vartanian T, Goodearl A, Lefebvre S, Park SK, Fischbach G.
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| Biochem Biophys Res Commun. 271(2):414-7. 2000
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34 | ERBB2, ERBB3
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| The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.
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| Waterman H, et al.
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| EMBO J 18(12):3348-58 1999
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35 | ERBB3
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| Interaction of the p23/p198 protein with ErbB-3.
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| Yoo JY, Hamburger AW.
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| Gene. 229(1-2):215-21. 1999
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36 | ERBB3
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| Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity.
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| Fernandes AM, Hamburger AW, Gerwin BI.
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| Am J Respir Cell Mol Biol. 21(6):701-9. 1999
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37 | ERBB3, NRG2
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| Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases.
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| Carraway KL 3rd, Weber JL, Unger MJ, Ledesma J, Yu N, Gassmann M, Lai C.
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| Nature. 387(6632):512-6. 1997
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38 | ERBB3, NRG1
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| Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3.
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| Horan T, Wen J, Arakawa T, Liu N, Brankow D, Hu S, Ratzkin B, Philo JS.
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| J Biol Chem. 270(41):24604-8. 1995
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39 | ERBB2, ERBB3, ERBB4
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| ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms.
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| Tzahar E, Levkowitz G, Karunagaran D, Yi L, Peles E, Lavi S, Chang D, Liu N, Yayon A, Wen D, et al.
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| J Biol Chem 269(40):25226-33. 1994
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40 | ERBB3
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| The erbB3 gene product is a receptor for heregulin.
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| Carraway KL, Sliwkowski MX, Akita R, Platko JV, Guy PM, Nuijens A, Diamonti AJ, Vandlen RL, Cantley LC, Cerione RA.
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| J Biol Chem 269(19):14303-6. 1994
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41 | ERBB3
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| c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase.
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| Katoh M, et al.
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| Biochem Biophys Res Commun 192 : 1189-1197. 1993
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42 | ERBB3
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| Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family : evidence for overexpression in a subset of human mammary tumors.
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| Kraus MH, et al.
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| Proc Natl Acad Sci U S A 86 : 9193-9197. 1989
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