Citations for
1ERBB2, ERBB3
CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.
Dahlhoff M, Gaborit N, Bultmann S, Leonhardt H, Yarden Y, Schneider MR.
FEBS J 284(19):3339-3349. doi: 10.1111/febs.14196. Epub 2017 Sep 14. 2017
2APIP, ERBB3
APIP, an ERBB3-binding partner, stimulates erbB2-3 heterodimer formation to promote tumorigenesis.
Hong SH, Lee WJ, Kim YD, Kim H, Jeon YJ, Lim B, Cho DH, Heo WD, Yang DH, Kim CY, Yang HK, Yang JK, Jung YK.
Oncotarget 7(16):21601-17. doi: 10.18632/oncotarget.7802. 2016
3CADM1, ERBB3, ERBB4
Necl-2/CADM1 interacts with ErbB4 and regulates its activity in GABAergic neurons.
Yamada A, Inoue E, Deguchi-Tawarada M, Matsui C, Togawa A, Nakatani T, Ono Y, Takai Y.
Mol Cell Neurosci 56C:234-243. doi: 10.1016/j.mcn.2013.06.003. [Epub ahead of print] 2013
4ERBB3
The receptor tyrosine kinase ErbB3 maintains the balance between luminal and basal breast epithelium.
Balko JM, Miller TW, Morrison MM, Hutchinson K, Young C, Rinehart C, Sánchez V, Jee D, Polyak K, Prat A, Perou CM, Arteaga CL, Cook RS.
Proc Natl Acad Sci U S A 109(1):221-6. doi: 10.1073/pnas.1115802109. Epub 2011 Dec 16. 2012
5ERBB2, ERBB3
Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling.
Zhang Q, Park E, Kani K, Landgraf R.
Proc Natl Acad Sci U S A 109(33):13237-42. doi: 10.1073/pnas.1200105109. Epub 2012 Jun 25. 2012
6ERBB2, ERBB3
Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase.
Garrett JT, Olivares MG, Rinehart C, Granja-Ingram ND, Sánchez V, Chakrabarty A, Dave B, Cook RS, Pao W, McKinely E, Manning HC, Chang J, Arteaga CL.
Proc Natl Acad Sci U S A 108(12):5021-6. Epub 2011 Mar 8. 2011
7ERBB3
A nuclear variant of ErbB3 receptor tyrosine kinase regulates ezrin distribution and Schwann cell myelination.
Adilakshmi T, Ness-Myers J, Madrid-Aliste C, Fiser A, Tapinos N.
J Neurosci. 31(13):5106-19. 2011
8ERBB3
ErbB3 ablation impairs PI3K/Akt-dependent mammary tumorigenesis.
Cook RS, Garrett JT, Sánchez V, Stanford JC, Young C, Chakrabarty A, Rinehart C, Zhang Y, Wu Y, Greenberger L, Horak ID, Arteaga CL.
Cancer Res 71(11):3941-51. Epub 2011 Apr 11. 2011
9ERBB3, RNF41
Post-transcriptional mechanisms contribute to the suppression of the ErbB3 negative regulator protein Nrdp1 in mammary tumors.
Ingalla EQ, Miller JK, Wald JH, Workman HC, Kaur RP, Yen L, Fry WH, Borowsky AD, Young LJ, Sweeney C, Carraway KL 3rd.
J Biol Chem 285(37):28691-7. Epub 2010 Jul 13. 2010
10ERBB3, SOST
Sclerostin-erbB-3 interactions: modulation of erbB-3 activity by sclerostin.
Craig TA, Kumar R.
Biochem Biophys Res Commun 402(2):421-4. Epub 2010 Oct 14. 2010
11ERBB3
NRG1 / ERBB3 signaling in melanocyte development and melanoma: inhibition of differentiation and promotion of proliferation.
Buac K, Xu M, Cronin J, Weeraratna AT, Hewitt SM, Pavan WJ.
Pigment Cell Melanoma Res 22(6):773-84. Epub 2009 Jul 30.PMID: 19659570 2009
12ERBB3
Structural analysis of the catalytically inactive kinase domain of the human EGF receptor 3.
Jura N, Shan Y, Cao X, Shaw DE, Kuriyan J.
Proc Natl Acad Sci U S A 106(51):21608-13. Epub 2009 Dec 9.PMID: 20007378 2009
13ERBB3
The ERBB3 receptor in cancer and cancer gene therapy.
Sithanandam G, Anderson LM.
Cancer Gene Ther 15(7):413-48. Epub 2008 Apr 11. Review. 2008
14ERBB3
High expression of HER3 is associated with a decreased survival in gastric cancer.
Hayashi M, Inokuchi M, Takagi Y, Yamada H, Kojima K, Kumagai J, Kawano T, Sugihara K.
Clin Cancer Res 14(23):7843-9.PMID: 19047113 2008
15ERBB3
HER3 is a determinant for poor prognosis in melanoma.
Reschke M, Mihic-Probst D, van der Horst EH, Knyazev P, Wild PJ, Hutterer M, Meyer S, Dummer R, Moch H, Ullrich A.
Clin Cancer Res 14(16):5188-97.PMID: 18698037 2008
16EGFR, ERBB2, ERBB3, ERBB4
N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.
Takahashi M, Yokoe S, Asahi M, Lee SH, Li W, Osumi D, Miyoshi E, Taniguchi N.
Biochim Biophys Acta 1780(3):520-4. Epub 2007 Nov 6.PMID: 18036567 2008
17ERBB3,LCCS2
Lethal Congenital Contractural Syndrome Type 2 (LCCS2) Is Caused by a Mutation in ERBB3 (Her3), a Modulator of the Phosphatidylinositol-3-Kinase/Akt Pathway.
Narkis G, Ofir R, Manor E, Landau D, Elbedour K, Birk OS.
Am J Hum Genet 81(3):589-95. Epub 2007 Jul 24. 2007
18EGFR, ERBB2, ERBB3, ERBB4
Characterization of a novel tripartite nuclear localization sequence in the EGFR family.
Hsu SC, Hung MC.
J Biol Chem 282(14):10432-40. Epub 2007 Feb 5. 2007
19ERBB3
Paired overexpression of ErbB3 and Sox10 in pilocytic astrocytoma.
Addo-Yobo SO, Straessle J, Anwar A, Donson AM, Kleinschmidt-Demasters BK, Foreman NK.
J Neuropathol Exp Neurol 65(8):769-75. 2006
20ERBB3
Tyrosine phosphorylation of PYK2 mediates heregulin-induced glioma invasion: novel heregulin/HER3-stimulated signaling pathway in glioma.
van der Horst EH, Weber I, Ullrich A.
Int J Cancer. 113(5):689-98. 2004
21NRG1, NRG2, NRG3, ERBB2, ERBB3, ERBB4, EGFR
Neuregulin promotes autophagic cell death of prostate cancer cells.
Tal-Or P, Di-Segni A, Lupowitz Z, Pinkas-Kramarski R.
Prostate 55(2):147-57. 2003
22ERBB3
Tetraspanin CD82 regulates compartmentalisation and ligand-induced dimerization of EGFR.
Odintsova E, Voortman J, Gilbert E, Berditchevski F.
J Cell Sci. 116(Pt 22):4557-66. 2003
23ERBB3
Identification of novel ErbB3-interacting factors using the split-ubiquitin membrane yeast two-hybrid system.
Thaminy S, Auerbach D, Arnoldo A, Stagljar I.
Genome Res. 13(7):1744-53. 2003
24ERBB3, RNF41
Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3.
Qiu XB, Goldberg AL.
Proc Natl Acad Sci U S A 99(23):14843-8. Epub 2002 Oct 31. Erratum in: Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):17220.. 2002
25ERBB3
Role of the N-terminus of epidermal growth factor in ErbB-2/ErbB-3 binding studied by phage display.
Stortelers C, Souriau C, van Liempt E, van de Poll ML, van Zoelen EJ.
Biochemistry. 41(27):8732-41. 2002
26ERBB3
An unexpected biochemical and functional interaction between gp130 and the EGF receptor family in breast cancer cells.
Grant SL, Hammacher A, Douglas AM, Goss GA, Mansfield RK, Heath JK, Begley CG.
Oncogene. 21(3):460-74. 2002
27ERBB3
Nrdp1/FLRF is a ubiquitin ligase promoting ubiquitination and degradation of the epidermal growth factor receptor family member, ErbB3.
Qiu XB, Goldberg AL.
Proc Natl Acad Sci U S A. 99(23):14843-8. 2002
28ERBB3
Mapping a heparin binding site on ErbB-3 epidermal growth factor receptor.
Adar R, Yayon A.
Biochem Biophys Res Commun 283(1):1-5. 2001
29ERBB3
Identification of a heregulin binding site in HER3 extracellular domain
Singer E, Landgraf R, Horan T, Slamon D, Eisenberg D.
J Biol Chem 276(47):44266-74. 2001
30ERBB3
Neuregulin-induced association of Sos Ras exchange protein with HER2(erbB2)/HER3(erbB3) receptor complexes in Schwann cells through a specific Grb2-HER2(erbB2) interaction.
Goodearl A, Viehover A, Vartanian T.
Dev Neurosci. 23(1):25-30. 2001
31ERBB3
Interaction of the PA2G4 (EBP1) protein with ErbB-3 and regulation of this binding by heregulin.
Yoo JY, Wang XW, Rishi AK, Lessor T, Xia XM, Gustafson TA, Hamburger AW.
Br J Cancer. 82(3):683-90. 2000
32ERBB3
Identification of an interaction between the angiotensin II receptor sub-type AT2 and the ErbB3 receptor, a member of the epidermal growth factor receptor family.
Knowle D, Ahmed S, Pulakat L.
Regul Pept. 87(1-3):73-82. 2000
33ERBB3
Neuregulin induces the rapid association of focal adhesion kinase with the erbB2-erbB3 receptor complex in schwann cells.
Vartanian T, Goodearl A, Lefebvre S, Park SK, Fischbach G.
Biochem Biophys Res Commun. 271(2):414-7. 2000
34ERBB2, ERBB3
The C-terminus of the kinase-defective neuregulin receptor ErbB-3 confers mitogenic superiority and dictates endocytic routing.
Waterman H, et al.
EMBO J 18(12):3348-58 1999
35ERBB3
Interaction of the p23/p198 protein with ErbB-3.
Yoo JY, Hamburger AW.
Gene. 229(1-2):215-21. 1999
36ERBB3
Dominance of ErbB-1 heterodimers in lung epithelial cells overexpressing ErbB-2. Both ErbB-1 and ErbB-2 contribute significantly to tumorigenicity.
Fernandes AM, Hamburger AW, Gerwin BI.
Am J Respir Cell Mol Biol. 21(6):701-9. 1999
37ERBB3, NRG2
Neuregulin-2, a new ligand of ErbB3/ErbB4-receptor tyrosine kinases.
Carraway KL 3rd, Weber JL, Unger MJ, Ledesma J, Yu N, Gassmann M, Lai C.
Nature. 387(6632):512-6. 1997
38ERBB3, NRG1
Binding of Neu differentiation factor with the extracellular domain of Her2 and Her3.
Horan T, Wen J, Arakawa T, Liu N, Brankow D, Hu S, Ratzkin B, Philo JS.
J Biol Chem. 270(41):24604-8. 1995
39ERBB2, ERBB3, ERBB4
ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms.
Tzahar E, Levkowitz G, Karunagaran D, Yi L, Peles E, Lavi S, Chang D, Liu N, Yayon A, Wen D, et al.
J Biol Chem 269(40):25226-33. 1994
40ERBB3
The erbB3 gene product is a receptor for heregulin.
Carraway KL, Sliwkowski MX, Akita R, Platko JV, Guy PM, Nuijens A, Diamonti AJ, Vandlen RL, Cantley LC, Cerione RA.
J Biol Chem 269(19):14303-6. 1994
41ERBB3
c-erbB3 gene encodes secreted as well as transmembrane receptor tyrosine kinase.
Katoh M, et al.
Biochem Biophys Res Commun 192 : 1189-1197. 1993
42ERBB3
Isolation and characterization of ERBB3, a third member of the ERBB/epidermal growth factor receptor family : evidence for overexpression in a subset of human mammary tumors.
Kraus MH, et al.
Proc Natl Acad Sci U S A 86 : 9193-9197. 1989