| 1 | ERBB2, NAE1, NEDD8
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| Neddylation of HER2 Inhibits its Protein Degradation and promotes Breast Cancer Progression
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| Xia X, Hu T, He X, Liu Y, Yu C, Kong W, Liao Y, Tang D, Liu J, Huang H.
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| Int J Biol Sci. Jan 1;19(2):377-392. doi: 10.7150/ijbs.75852. 2023
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| 2 | ERBB2, FUT4, SMYD2
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| SMYD2 facilitates cancer cell malignancy and xenograft tumor development through ERBB2-mediated FUT4 expression in colon cancer.
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| Lai Y, Yang Y.
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| Mol Cell Biochem. Apr 27. doi: 10.1007/s11010-020-03738-2. Online ahead of print 2020
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| 3 | EGRF, ERBB2, MET, PLXNB1, SEMA3C
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| SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1.
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| Peacock JW, Takeuchi A, Hayashi N, Liu L, Tam KJ, Al Nakouzi N, Khazamipour N, Tombe T, Dejima T, Lee KC, Shiota M, Thaper D, Lee WC, Hui DH, Kuruma H, Ivanova L, Yenki P, Jiao IZ, Khosravi S, Mui AL, Fazli L, Zoubeidi A, Daugaard M, Gleave ME, Ong CJ.
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| EMBO Mol Med 10(2):219-238. doi: 10.15252/emmm.201707689.
2018
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| 4 | ERBB2
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| Association of HER2 gene amplification and tumor progression in early gastric cancer.
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| Kanayama K, Imai H, Usugi E, Shiraishi T, Hirokawa YS, Watanabe M.
|
| Virchows Arch 473(5):559-565. doi: 10.1007/s00428-018-2433-y. Epub 2018 Aug 17.
2018
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| 5 | BECN1, ERBB2
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| Increased autophagy blocks HER2-mediated breast tumorigenesis.
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| Vega-Rubín-de-Celis S, Zou Z, Fernández ÁF, Ci B, Kim M, Xiao G, Xie Y, Levine B.
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| Proc Natl Acad Sci U S A 115(16):4176-4181. doi: 10.1073/pnas.1717800115. Epub 2018 Apr 2.
2018
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| 6 | ERBB2, STARD13
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| In vivo evidence supporting a metastasis suppressor role for Stard13 (Dlc2) in ErbB2 (Neu) oncogene induced mouse mammary tumors.
|
| Basak P, Leslie H, Dillon RL, Muller WJ, Raouf A, Mowat MRA.
|
| Genes Chromosomes Cancer 57(4):182-191. doi: 10.1002/gcc.22519. Epub 2017 Dec 29.
2018
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| 7 | ERBB2
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| A novel HER2 gene body enhancer contributes to HER2 expression.
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| Liu Q, Kulak MV, Borcherding N, Maina PK, Zhang W, Weigel RJ, Qi HH.
|
| Oncogene 37(5):687-694. doi: 10.1038/onc.2017.382. Epub 2017 Oct 16.
2018
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| 8 | DDX6, ERBB2, FGFR2
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| DEAD-Box Protein RNA-Helicase DDX6 Regulates the Expression of HER2 and FGFR2 at the Post-Transcriptional Step in Gastric Cancer Cells.
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| Tajirika T, Tokumaru Y, Taniguchi K, Sugito N, Matsuhashi N, Futamura M, Yanagihara K, Akao Y, Yoshida K.
|
| Int J Mol Sci 19(7). pii: E2005. doi: 10.3390/ijms19072005.
2018
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| 9 | ERBB2, NUMB, NUMBL, RAB7A
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| Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation.
|
| Hirai M, Arita Y, McGlade CJ, Lee KF, Chen J, Evans SM.
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| J Clin Invest 127(2):569-582. doi: 10.1172/JCI91081. Epub 2017 Jan 9. 2017
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| 10 | ERBB2, SMYD3
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| Protein lysine methyltransferase SMYD3 is involved in tumorigenesis through regulation of HER2 homodimerization.
|
| Yoshioka Y, Suzuki T, Matsuo Y, Tsurita G, Watanabe T, Dohmae N, Nakamura Y, Hamamoto R.
|
| Cancer Med 6(7):1665-1672. doi: 10.1002/cam4.1099. Epub 2017 Jun 22.
2017
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| 11 | AKT1, ERBB2
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| The ectodomain of cadherin-11 binds to erbB2 and stimulates Akt phosphorylation to promote cranial neural crest cell migration.
|
| Mathavan K, Khedgikar V, Bartolo V, Alfandari D.
|
| PLoS One 12(11):e0188963. doi: 10.1371/journal.pone.0188963. eCollection 2017.
2017
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| 12 | ERBB2
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| Tumor-linked HER2 expression: association with obesity and lipid-related microenvironment.
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| Ray A.
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| Horm Mol Biol Clin Investig 32(3). pii: /j/hmbci.2017.32.issue-3/hmbci-2017-0020/hmbci-2017-0020.xml. doi: 10.1515/hmbci-2017-0020. Review.
2017
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| 13 | ERBB2, ERBB3
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| CRISPR-assisted receptor deletion reveals distinct roles for ERBB2 and ERBB3 in skin keratinocytes.
|
| Dahlhoff M, Gaborit N, Bultmann S, Leonhardt H, Yarden Y, Schneider MR.
|
| FEBS J 284(19):3339-3349. doi: 10.1111/febs.14196. Epub 2017 Sep 14.
2017
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| 14 | ERBB2
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| Investigation of the role of DNA methylation in the expression of ERBB2 in human myocardium.
|
| Quiñones-Lombraña A, Blair RH, Blanco JG.
|
| Gene 628:286-294. doi: 10.1016/j.gene.2017.07.058. Epub 2017 Jul 21.
2017
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| 15 | ATP2B2, ERBB2, HSP90AB1
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| HER2 signaling regulates HER2 localization and membrane retention.
|
| Jeong J, Kim W, Kim LK, VanHouten J, Wysolmerski JJ.
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| PLoS One 12(4):e0174849. doi: 10.1371/journal.pone.0174849. eCollection 2017.
2017
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| 16 | ATP2B2, ERBB2, SLC9A3R1
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| The scaffolding protein NHERF1 regulates the stability and activity of the tyrosine kinase HER2.
|
| Jeong J, VanHouten JN, Kim W, Dann P, Sullivan C, Choi J, Sneddon WB, Friedman PA, Wysolmerski JJ.
|
| J Biol Chem 292(16):6555-6568. doi: 10.1074/jbc.M116.770883. Epub 2017 Feb 24.
2017
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| 17 | ERBB2, FSIP1
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| FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.
|
| Liu T, Zhang H, Sun L, Zhao D, Liu P, Yan M, Zaidi N, Izadmehr S, Gupta A, Abu-Amer W, Luo M, Yang J, Ou X, Wang Y, Bai X, Wang Y, New MI, Zaidi M, Yuen T, Liu C.
|
| Proc Natl Acad Sci U S A. Jul 18;114(29):7683-7688. doi: 10.1073/pnas.1621486114. Epub 2017 Jul 2017
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| 18 | ATP2B2, ERBB2
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| PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
|
| Jeong J, VanHouten JN, Dann P, Kim W, Sullivan C, Yu H, Liotta L, Espina V, Stern DF, Friedman PA, Wysolmerski JJ.
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| Proc Natl Acad Sci U S A 113(3):E282-90. doi: 10.1073/pnas.1516138113.
2016
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| 19 | EPX, ERBB2
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| Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling.
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| Hennigan K, Conroy PJ, Walsh MT, Amin M, O'Kennedy R, Ramasamy P, Gleich GJ, Siddiqui Z, Glynn S, McCabe O, Mooney C, Harvey BJ, Costello RW, McBryan J.
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| Clin Immunol 171:1-11. doi: 10.1016/j.clim.2016.08.009. Epub 2016 Aug 9.
2016
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| 20 | ERBB2, PERP, SPRY2
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| ErbB2-dependent downregulation of a pro-apoptotic protein Perp is required for oncogenic transformation of breast epithelial cells.
|
| Khan IA, Yoo BH, Masson O, Baron S, Corkery D, Dellaire G, Attardi LD, Rosen KV.
|
| Oncogene 35(44):5759-5769. doi: 10.1038/onc.2016.109. Epub 2016 Apr 25.
2016
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| 21 | ERBB2, FASN
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| FASN, ErbB2-mediated glycolysis is required for breast cancer cell migration.
|
| Zhou L, Jiang S, Fu Q, Smith K, Tu K, Li H, Zhao Y.
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| Oncol Rep 35(5):2715-22. doi: 10.3892/or.2016.4627. Epub 2016 Feb 19.
2016
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| 22 | ATP2B2, ERBB2
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| PMCA2 regulates HER2 protein kinase localization and signaling and promotes HER2-mediated breast cancer.
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| Jeong J, VanHouten JN, Dann P, Kim W, Sullivan C, Yu H, Liotta L, Espina V, Stern DF, Friedman PA, Wysolmerski JJ.
|
| Proc Natl Acad Sci U S A 113(3):E282-90. doi: 10.1073/pnas.1516138113. Epub 2016 Jan 4.
2016
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| 23 | AVPR2, EGFR, ERBB2
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| Therapeutic targets for polycystic kidney disease
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| Wilson PD.
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| Expert Opin Ther Targets. 2016;20(1):35-45. doi: 10.1517/14728222.2015.1083979. Epub 2015 Aug 31. 2016
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| 24 | ERBB2, KRT19
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| Cytokeratin19 induced by HER2/ERK binds and stabilizes HER2 on cell membranes.
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| Ju JH, Oh S, Lee KM, Yang W, Nam KS, Moon HG, Noh DY, Kim CG, Park G, Park JB, Lee T, Arteaga CL, Shin I.
|
| Cell Death Differ 22(4):665-76. doi: 10.1038/cdd.2014.155. Epub 2014 Oct 24.
2015
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| 25 | ERBB2, MAP3K11
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| Human Epidermal Growth Factor Receptor 2 (HER2) Impedes MLK3 Kinase Activity to Support Breast Cancer Cell Survival.
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| Das S, Sondarva G, Viswakarma N, Nair RS, Osipo C, Tzivion G, Rana B, Rana A.
|
| J Biol Chem 290(35):21705-12. doi: 10.1074/jbc.M115.655563. Epub 2015 Jul 7.
2015
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| 26 | ERBB2
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| HER2 missense mutations have distinct effects on oncogenic signaling and migration.
|
| Zabransky DJ, Yankaskas CL, Cochran RL, Wong HY, Croessmann S, Chu D, Kavuri SM, Red Brewer M, Rosen DM, Dalton WB, Cimino-Mathews A, Cravero K, Button B, Kyker-Snowman K, Cidado J, Erlanger B, Parsons HA, Manto KM, Bose R, Lauring J, Arteaga CL, Konstantopoulos K, Park BH.
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| Proc Natl Acad Sci U S A 112(45):E6205-14. doi: 10.1073/pnas.1516853112. Epub 2015 Oct 27.
2015
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| 27 | ERBB2, HNRNPH1, SRSF3
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| SRSF3 and hnRNP H1 regulate a splicing hotspot of HER2 in breast cancer cells.
|
| Gautrey H, Jackson C, Dittrich AL, Browell D, Lennard T, Tyson-Capper A.
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| RNA Biol 12(10):1139-51. doi: 10.1080/15476286.2015.1076610. Epub 2015 Sep 14.
2015
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| 28 | ERBB2, ERBIN
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| Role of Erbin in ErbB2-dependent breast tumor growth.
|
| Tao Y, Shen C, Luo S, Traoré W, Marchetto S, Santoni MJ, Xu L, Wu B, Shi C, Mei J, Bates R, Liu X, Zhao K, Xiong WC, Borg JP, Mei L.
|
| Proc Natl Acad Sci U S A 111(42):E4429-38. doi: 10.1073/pnas.1407139111.
2014
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| 29 | ERBB2, LINGO1
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| LINGO-1 regulates oligodendrocyte differentiation by inhibiting ErbB2 translocation and activation in lipid rafts.
|
| Lee X, Shao Z, Sheng G, Pepinsky B, Mi S.
|
| Mol Cell Neurosci 60:36-42. doi: 10.1016/j.mcn.2014.02.006. Epub 2014 Feb 28.
2014
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| 30 | ERBB2, HOTAIR, MYC, PTEN, RBM38, WIF1
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| The molecular mechanism of HOTAIR in tumorigenesis, metastasis, and drug resistance.
|
| Zhou X, Chen J, Tang W.
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| Acta Biochim Biophys Sin (Shanghai) 46(12):1011-5. doi: 10.1093/abbs/gmu104. Epub 2014 Nov 10. Review.
2014
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| 31 | ERBB2, FASN
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| Interaction between fatty acid synthase and human epidermal growth receptor 2 (HER2) in osteosarcoma cells.
|
| Long XH, Zhao K, Zhang GM, Zhou Y, Zhou RP, Liu ZL, Zhang ZH.
|
| Int J Clin Exp Pathol 7(12):8777-83. eCollection 2014.
2014
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| 32 | BDNF, ERBB2, NRG1
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| RET and NRG1 interplay in Hirschsprung disease.
|
| Gui H, Tang WK, So MT, Proitsi P, Sham PC, Tam PK, Sau-Wai Ngan E, Cherny SS, Garcia-Barceló MM.
|
| Hum Genet 132(5):591-600. doi: 10.1007/s00439-013-1272-9. Epub 2013 Feb 12.
2013
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| 33 | ERBB2, LOXL2
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| LOXL2 induces aberrant acinar morphogenesis via ErbB2 signaling.
|
| Chang J, Nicolau MM, Cox TR, Wetterskog D, Martens JW, Barker HE, Erler JT.
|
| Breast Cancer Res 15(4):R67.
2013
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| 34 | ERBB2, ERBIN, NRG1
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| Differential expression of neuregulin-1 isoforms and downregulation of erbin are associated with Erb B2 receptor activation in diabetic peripheral neuropathy.
|
| Pan P, Dobrowsky RT.
|
| Acta Neuropathol Commun 1:39. doi: 10.1186/2051-5960-1-39.
2013
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| 35 | ERBB2, MMP9
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| MMP-9 increases HER2/neu expression and alters apoptosis levels in human mammary epithelial cells (HMEC).
|
| Fatunmbi M, Shelton J, Aronica SM.
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| Breast Cancer Res Treat 135(2):519-30. doi: 10.1007/s10549-012-2191-5. Epub 2012 Aug 10.
2012
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| 36 | ERBB2, ERBB3
|
| Functional isolation of activated and unilaterally phosphorylated heterodimers of ERBB2 and ERBB3 as scaffolds in ligand-dependent signaling.
|
| Zhang Q, Park E, Kani K, Landgraf R.
|
| Proc Natl Acad Sci U S A 109(33):13237-42. doi: 10.1073/pnas.1200105109. Epub 2012 Jun 25.
2012
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| 37 | ERBB2, ERBIN, NRG1
|
| Erbin is required for myelination in regenerated axons after injury.
|
| Liang C, Tao Y, Shen C, Tan Z, Xiong WC, Mei L.
|
| J Neurosci 32(43):15169-80. doi: 10.1523/JNEUROSCI.2466-12.2012.
2012
|
| 38 | ADAM12, ERBB2
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| A positive feedback loop between HER2 and ADAM12 in human head and neck cancer cells increases migration and invasion.
|
| Rao VH, Kandel A, Lynch D, Pena Z, Marwaha N, Deng C, Watson P, Hansen LA.
|
| Oncogene 31(23):2888-98. doi: 10.1038/onc.2011.460. Epub 2011 Oct 10.
2012
|
| 39 | ERBB2
|
| In Vitro Selection of RNA Aptamer and Specific Targeting of ErbB2 in Breast Cancer Cells.
|
| Kim MY, Jeong S.
|
| Oligonucleotides ligonucleotides. 2011 Jun 6. [Epub ahead of print]
2011
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| 40 | ERBB2
|
| The Functional Crosstalk between HER2 Tyrosine Kinase and TGF-β Signaling in Breast Cancer Malignancy.
|
| Wang SE.
|
| J Signal Transduct 2011:804236. Epub 2011 Feb 24.
2011
|
| 41 | ERBB2
|
| When Tumor Suppressor TGFβ Meets the HER2 (ERBB2) Oncogene.
|
| Chow A, Arteaga CL, Wang SE.
|
| J Mammary Gland Biol Neoplasia 16(2):81-8. Epub 2011 Apr 6.
2011
|
| 42 | ERBB2
|
| A novel fully human antitumour immunoRNase targeting ErbB2-positive tumours.
|
| Borriello M, Laccetti P, Terrazzano G, D'Alessio G, De Lorenzo C.
|
| Br J Cancer 104(11):1716-23. Epub 2011 May 10.
2011
|
| 43 | ERBB2
|
| Nuclear ErbB2 Enhances Translation and Cell Growth by Activating Transcription of Ribosomal RNA Genes.
|
| Li LY, Chen H, Hsieh YH, Wang YN, Chu HJ, Chen YH, Chen HY, Chien PJ, Ma HT, Tsai HC, Lai CC, Sher YP, Lien HC, Tsai CH, Hung MC.
|
| Cancer Res ancer Res. 2011 Jun 7. [Epub ahead of print]
2011
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| 44 | ERBB2
|
| Assessment of ErbB2 (Her2) in oesophageal adenocarcinomas: summary of a revised immunohistochemical evaluation system, bright field double in situ hybridisation and fluorescence in situ hybridisation.
|
| Langer R, Rauser S, Feith M, Nährig JM, Feuchtinger A, Friess H, Höfler H, Walch A.
|
| Mod Pathol od Pathol. 2011 Apr 22. [Epub ahead of print]
2011
|
| 45 | ERBB2, ERBB3
|
| Transcriptional and posttranslational up-regulation of HER3 (ErbB3) compensates for inhibition of the HER2 tyrosine kinase.
|
| Garrett JT, Olivares MG, Rinehart C, Granja-Ingram ND, Sánchez V, Chakrabarty A, Dave B, Cook RS, Pao W, McKinely E, Manning HC, Chang J, Arteaga CL.
|
| Proc Natl Acad Sci U S A 108(12):5021-6. Epub 2011 Mar 8.
2011
|
| 46 | DTNA, ERBB2, ERBB4, NRG1
|
| Neuregulin/ErbB regulate neuromuscular junction development by phosphorylation of α-dystrobrevin.
|
| Schmidt N, Akaaboune M, Gajendran N, Martinez-Pena y Valenzuela I, Wakefield S, Thurnheer R, Brenner HR.
|
| J Cell Biol 195(7):1171-84. doi: 10.1083/jcb.201107083. Epub 2011 Dec 19.
2011
|
| 47 | EGFR, ERBB2, PTPN9
|
| Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells.
|
| Yuan T, Wang Y, Zhao ZJ, Gu H.
|
| J Biol Chem 285(20):14861-70. Epub 2010 Mar 24.PMID: 20335174 2010
|
| 48 | ERBB2, NRG1
|
| Nrg1/ErbB signaling networks in Schwann cell development and myelination.
|
| Newbern J, Birchmeier C.
|
| Semin Cell Dev Biol emin Cell Dev Biol. 2010 Sep 9. [Epub ahead of print]PMID: 20832498 2010
|
| 49 | ERBB2
|
| ErbB2 requires integrin alpha5 for anoikis resistance via Src regulation of receptor activity in human mammary epithelial cells.
|
| Haenssen KK, Caldwell SA, Shahriari KS, Jackson SR, Whelan KA, Klein-Szanto AJ, Reginato MJ.
|
| J Cell Sci 123(Pt 8):1373-82. Epub 2010 Mar 23.PMID: 20332114 2010
|
| 50 | ERBB2, PIN1
|
| The prolyl isomerase Pin1 enhances HER-2 expression and cellular transformation via its interaction with mitogen-activated protein kinase/extracellular signal-regulated kinase kinase 1.
|
| Khanal P, Namgoong GM, Kang BS, Woo ER, Choi HS.
|
| Mol Cancer Ther 9(3):606-16. Epub 2010 Feb 23.PMID: 20179161 2010
|
| 51 | BECN1, ERBB2
|
| Chromosome band 17q21 in breast cancer: significant association between beclin 1 loss and HER2/NEU amplification.
|
| Negri T, Tarantino E, Orsenigo M, Reid JF, Gariboldi M, Zambetti M, Pierotti MA, Pilotti S.
|
| Genes Chromosomes Cancer 49(10):901-9.PMID: 20589936 2010
|
| 52 | ERBB2, MACF1
|
| ErbB2 receptor controls microtubule capture by recruiting ACF7 to the plasma membrane of migrating cells.
|
| Zaoui K, Benseddik K, Daou P, Salaün D, Badache A.
|
| Proc Natl Acad Sci U S A 107(43):18517-22. Epub 2010 Oct 11.
2010
|
| 53 | CCNA2, ERBB2
|
| Prediction of recurrence risk in early breast cancer using human epidermal growth factor 2 and cyclin A2.
|
| Li HP, Ji JF, Hou KY, Lei YT, Zhao HM, Wang J, Zheng J, Liu JY, Wang MP, Xiao Y, Wang YF, Lü YY, Sun Y.
|
| Chin Med J (Engl) 123(4):431-7. Erratum in: Chin Med J (Engl). 2010 Mar;123(5):562.
2010
|
| 54 | ERBB2
|
| ErbB2 resembles an autoinhibited invertebrate epidermal growth factor receptor.
|
| Alvarado D, Klein DE, Lemmon MA.
|
| Nature 461(7261):287-91. Epub 2009 Aug 30.PMID: 19718021 2009
|
| 55 | CFL1, ERBB2, MEMO1, PLCG1
|
| Memo is a cofilin-interacting protein that influences PLCgamma1 and cofilin activities, and is essential for maintaining directionality during ErbB2-induced tumor-cell migration.
|
| Meira M, Masson R, Stagljar I, Lienhard S, Maurer F, Boulay A, Hynes NE.
|
| J Cell Sci 122(Pt 6):787-97. Epub 2009 Feb 17.
2009
|
| 56 | ERBB2, LDHA
|
| Upregulation of lactate dehydrogenase A by ErbB2 through heat shock factor 1 promotes breast cancer cell glycolysis and growth.
|
| Zhao YH, Zhou M, Liu H, Ding Y, Khong HT, Yu D, Fodstad O, Tan M.
|
| Oncogene 28(42):3689-701. doi: 10.1038/onc.2009.229. Epub 2009 Aug 10.
2009
|
| 57 | ERBB2
|
| Direct resequencing of the complete ERBB2 coding sequence reveals an absence of activating mutations in ERBB2 amplified breast cancer.
|
| Zito CI, Riches D, Kolmakova J, Simons J, Egholm M, Stern DF.
|
| Genes Chromosomes Cancer 47(7):633-8. 2008
|
| 58 | APC, ATM, EPHA3, ERBB2, ERBB4, FGFR4
|
| Somatic mutations affect key pathways in lung adenocarcinoma.
|
| Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK.
|
| Nature 455(7216):1069-75.
2008
|
| 59 | ERBB2, ETS1, MMP1
|
| Ets-1 upregulates HER2-induced MMP-1 expression in breast cancer cells.
|
| Park YH, Jung HH, Ahn JS, Im YH.
|
| Biochem Biophys Res Commun 377(2):389-94. Epub 2008 Oct 11.
2008
|
| 60 | ERBB2, RNF11, WWP1
|
| The WW domain containing E3 ubiquitin protein ligase 1 upregulates ErbB2 and EGFR through RING finger protein 11.
|
| Chen C, Zhou Z, Liu R, Li Y, Azmi PB, Seth AK.
|
| Oncogene 27(54):6845-55. Epub 2008 Aug 25. 2008
|
| 61 | EGFR, ERBB2, ERBB3, ERBB4
|
| N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.
|
| Takahashi M, Yokoe S, Asahi M, Lee SH, Li W, Osumi D, Miyoshi E, Taniguchi N.
|
| Biochim Biophys Acta 1780(3):520-4. Epub 2007 Nov 6.PMID: 18036567 2008
|
| 62 | ERBB2
|
| Identification of the domain in ErbB2 that restricts ligand-induced degradation.
|
| Shen F, Lin Q, Childress C, Yang W.
|
| Cell Signal 20(4):779-86. Epub 2008 Jan 7.PMID: 18255265 2008
|
| 63 | ERBB2, PTK6
|
| Brk is coamplified with ErbB2 to promote proliferation in breast cancer.
|
| Xiang B, Chatti K, Qiu H, Lakshmi B, Krasnitz A, Hicks J, Yu M, Miller WT, Muthuswamy SK.
|
| Proc Natl Acad Sci U S A 105(34):12463-8. Epub 2008 Aug 21.PMID: 18719096 2008
|
| 64 | DOCK7, ERBB2
|
| ErbB2 directly activates the exchange factor Dock7 to promote Schwann cell migration.
|
| Yamauchi J, Miyamoto Y, Chan JR, Tanoue A.
|
| J Cell Biol 181(2):351-65. doi: 10.1083/jcb.200709033.
2008
|
| 65 | EGFR, ERBB2, ERBB3, ERBB4
|
| Characterization of a novel tripartite nuclear localization sequence in the EGFR family.
|
| Hsu SC, Hung MC.
|
| J Biol Chem 282(14):10432-40. Epub 2007 Feb 5. 2007
|
| 66 | ERBB2, WWOX
|
| Wwox suppresses prostate cancer cell growth through modulation of ErbB2-mediated androgen receptor signaling.
|
| Qin HR, Iliopoulos D, Nakamura T, Costinean S, Volinia S, Druck T, Sun J, Okumura H, Huebner K.
|
| Mol Cancer Res 5(9):957-65. Epub 2007 Aug 17.PMID: 17704139 2007
|
| 67 | ERBB2
|
| erbB2 is required for G protein-coupled receptor signaling in the heart.
|
| Negro A, Brar BK, Gu Y, Peterson KL, Vale W, Lee KF.
|
| Proc Natl Acad Sci U S A 103(43):15889-93. Epub 2006 Oct 16. 2006
|
| 68 | ERBB2
|
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| Stable RNA interference of ErbB-2 gene synergistic with epirubicin suppresses breast cancer growth in vitro and in vivo.
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| ERBB2 kinase domain mutation in the lung squamous cell carcinoma.
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| Cancer Lett 237(1):89-94. Epub 2005 Jul 18. 2006
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| 71 | ERBB2, ERBB4
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| Synapses form in skeletal muscles lacking neuregulin receptors.
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| The antagonistic regulation of human MUC4 and ErbB-2 genes by the Ets protein PEA3 in pancreatic cancer cells: implications for the proliferation/differentiation balance in the cells.
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| 73 | ERBB2,LNX1
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| Young P, Nie J, Wang X, McGlade CJ, Rich MM, Feng G.
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| Mol Cell Neurosci 30(2):238-48. 2005
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| 74 | TOP2A, ERBB2
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| Amplification of the TOP2A gene does not predict high levels of topoisomerase II alpha protein in human breast tumor samples.
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| Mueller RE, Parkes RK, Andrulis I, O'Malley FP.
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| 75 | TOP2A, ERBB2, TSG17G, THRAP4
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| Genes Chromosomes Cancer 40(1):19-31. 2004
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| 76 | ERBB2
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| Proc Natl Acad Sci U S A 101(49):17138-43. Epub 2004 Dec 7. 2004
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| Oncogene 23(14):2564-75. 2004
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| 78 | ERBB2
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| Quantitative assessment of HER2/neu expression by real-time PCR and fluorescent in situ hybridization analysis in low-grade osteosarcoma.
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| Lee WI, Bacchni P, Bertoni F, Maeng YH, Park YK.
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| Oncol Rep 12(1):125-8. 2004
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| 79 | ERBB2
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| Synchronous overexpression of epidermal growth factor receptor and HER2-neu protein is a predictor of poor outcome in patients with stage I non-small cell lung cancer.
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| Onn A, Correa AM, Gilcrease M, Isobe T, Massarelli E, Bucana CD, O'Reilly MS, Hong WK, Fidler IJ, Putnam JB, Herbst RS.
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| Clin Cancer Res 10(1 Pt 1):136-43. 2004
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| 80 | NRG1, NRG2, NRG3, ERBB2, ERBB3, ERBB4, EGFR
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| Neuregulin promotes autophagic cell death of prostate cancer cells.
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| Tal-Or P, Di-Segni A, Lupowitz Z, Pinkas-Kramarski R.
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| Prostate 55(2):147-57. 2003
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| 81 | ERBB2, GRB7, MIEN1, PGAP3, PNMT, PPP2R1B, STARD3, TCAP
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| MGC9753 gene, located within PPP1R1B-STARD3-ERBB2-GRB7 amplicon on human chromosome 17q12, encodes the seven-transmembrane receptor with extracellular six-cystein domain.
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| Int J Oncol 22(6):1369-74. 2003
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| 82 | ERBB2
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| Vernimmen D, Gueders M, Pisvin S, Delvenne P, Winkler R.
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| Br J Cancer 89(5):899-906. 2003
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| 83 | CASC4, ERBB2
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| 84 | ERBB2
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| ErbB2 is essential in the prevention of dilated cardiomyopathy.
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| 85 | ERBB2
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| Conditional mutation of the ErbB2 (HER2) receptor in cardiomyocytes leads to dilated cardiomyopathy.
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| 86 | ERBB2
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| Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas.
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| 87 | ERBB2
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| 88 | PTGS2, ERBB2
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| Hepatology 36(2):439-50. 2002
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| 89 | EGFR, ERBB2
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| Differential cytoskeletal association of ErbB1 and ErbB2 during keratinocyte differentiation.
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| Kansra S, Stoll SW, Elder JT.
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| Biochem Biophys Res Commun 295(5):1108-17. 2002
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| 90 | ERBB2
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| Expression of a truncated 100 kDa HER2 splice variant acts as an endogenous inhibitor of tumour cell proliferation.
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| 91 | ERBB2
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| AP-2 transcription factors in the regulation of ERBB2 gene transcription by oestrogen.
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| 92 | EGFR, ERBB2
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| 93 | ERBB2, KRAS1P
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| Mutations and amplification of oncogenes in endometrial cancer.
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| Oncology 56(1):59-65. 1999
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| 94 | ERBB2
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| HER-2/neu (c-erb-B2) gene and protein in breast cancer.
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| Am J Clin Pathol 112(1 Suppl 1):S53-67. Review 1999
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| 97 | ERBB2, ERBB3
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| Rescue of the cardiac defect in ErbB2 mutant mice reveals essential roles of ErbB2 in peripheral nervous system development.
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| Morris JK, Lin W, Hauser C, Marchuk Y, Getman D, Lee KF.
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| Neuron 23(2):273-83. 1999
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| Nature 393(6680):83-5. 1998
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| 101 | ERBB2
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| Assignment of v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 (ERBB2) to human chromosome band 17q21.1 by in situ hybridization.
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| 102 | ERBB2, GRB7
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| Molecular cloning of human GRB-7 co-amplified with CAB1 and c-ERBB-2 in primary gastric cancer.
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| Biochem Biophys Res Commun 232 : 5-9. 1997
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| 103 | ERBB2, TRAF4, STARD3
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| Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer.
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| 104 | CTNNB1, ERBB2
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| c-erbB-2 gene product directly associates with beta-catenin and plakoglobin.
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| ErbB-3 and ErbB-4 function as the respective low and high affinity receptors of all Neu differentiation factor/heregulin isoforms.
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| Characterization of a new allele of the human ERBB2 gene by allele-specific competition hybridization.
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| 107 | ERBB2
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| Amplification of the HER-2/neu protooncogene in human endocrine tumors.
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| Surgery 112 : 211-218. 1992
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| 108 | BCR, RAF1, ERBB2, CSF1R
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| Metaphase and interphase cytogenetics with Alu-PCR-amplified yeast artificial chromosome clones containing the BCR gene and the protooncogenes c-raf-1, c-fms, and c-erbB-2.
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| Cancer Res 52 : 2590-2596. 1992
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| Detection and temporal appearance of multiple copies of c-erb-B2 genesin advanced mammary carcinoma using fine needle biopsies and the polymerase chain reaction.
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| PCR detection of an MboI polymorphism in the ERBB2 (HER2; NEU) gene on chromosome 17q11.2-q12.
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| G to A polymorphism at amino acid codon 655 of the human erbB-2/HER2 gene.
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| Localization of the human erbB-2 gene on normal and rearranged chromosomes 17 to bands q12-21.32.
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| 117 | ERBB2
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| A Mr=190,000 glycoprotein phosphorylated on tyrosine residues in epidermal growth factor stimulated KB cells is the product of the C-erbB-2 gene.
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| 122 | EGFR, ERBB2
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