1 | EPX, MPO, TNFSF11
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| Peroxidase enzymes inhibit osteoclast differentiation and bone resorption.
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| Panagopoulos V, Liapis V, Zinonos I, Hay S, Leach DA, Ingman W, DeNichilo MO, Atkins GJ, Findlay DM, Zannettino ACW, Evdokiou A.
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| Mol Cell Endocrinol 440:8-15. doi: 10.1016/j.mce.2016.11.007. Epub 2016 Nov 9.
2017
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2 | EPX, MPO
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| Inflammatory peroxidases promote breast cancer progression in mice via regulation of the tumour microenvironment.
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| Panagopoulos V, Leach DA, Zinonos I, Ponomarev V, Licari G, Liapis V, Ingman WV, Anderson P, DeNichilo MO, Evdokiou A.
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| Int J Oncol 50(4):1191-1200. doi: 10.3892/ijo.2017.3883. Epub 2017 Feb 20.
2017
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3 | EPX, ERBB2
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| Eosinophil peroxidase activates cells by HER2 receptor engagement and β1-integrin clustering with downstream MAPK cell signaling.
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| Hennigan K, Conroy PJ, Walsh MT, Amin M, O'Kennedy R, Ramasamy P, Gleich GJ, Siddiqui Z, Glynn S, McCabe O, Mooney C, Harvey BJ, Costello RW, McBryan J.
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| Clin Immunol 171:1-11. doi: 10.1016/j.clim.2016.08.009. Epub 2016 Aug 9.
2016
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4 | EPX, MPO
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| Uncovering a new role for peroxidase enzymes as drivers of angiogenesis.
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| Panagopoulos V, Zinonos I, Leach DA, Hay SJ, Liapis V, Zysk A, Ingman WV, DeNichilo MO, Evdokiou A.
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| Int J Biochem Cell Biol 68:128-38. doi: 10.1016/j.biocel.2015.09.006. Epub 2015 Sep 18.
2015
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5 | EPX
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| Eosinophil peroxidase induces expression of cholinergic genes via cell surface neural interactions.
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| Akasheh N, Walsh MT, Costello RW.
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| Mol Immunol 62(1):37-45. doi: 10.1016/j.molimm.2014.05.014. Epub 2014 Jun 14.
2014
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6 | EPX, RNASE3
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| The production of the eosinophil proteins ECP and EPX/EDN are regulated in a reciprocal manner.
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| Jönsson UB, Blom K, Stålenheim G, Håkansson LD, Venge P.
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| APMIS 122(4):283-91. doi: 10.1111/apm.12142.
2014
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7 | EPX
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| Eosinophil peroxidase in sputum represents a unique biomarker of airway eosinophilia.
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| Nair P, Ochkur SI, Protheroe C, Radford K, Efthimiadis A, Lee NA, Lee JJ.
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| Allergy 68(9):1177-84. doi: 10.1111/all.12206. Epub 2013 Aug 9.
2013
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8 | EPX, PRG2
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| Expression of the secondary granule proteins major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX) is required for eosinophilopoiesis in mice.
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| Doyle AD, Jacobsen EA, Ochkur SI, McGarry MP, Shim KG, Nguyen DT, Protheroe C, Colbert D, Kloeber J, Neely J, Shim KP, Dyer KD, Rosenberg HF, Lee JJ, Lee NA.
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| Blood 122(5):781-90. doi: 10.1182/blood-2013-01-473405. Epub 2013 Jun 4.
2013
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9 | EPX, RNASE3
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| Eosinophil associated genes in the inflammatory bowel disease 4 region: correlation to inflammatory bowel disease revealed.
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| Blom K, Rubin J, Halfvarson J, Törkvist L, Rönnblom A, Sangfelt P, Lördal M, Jönsson UB, Sjöqvist U, Håkansson LD, Venge P, Carlson M.
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| World J Gastroenterol 18(44):6409-19; discussion p. 6417-8. doi: 10.3748/wjg.v18.i44.6409.
2012
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10 | EPX
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| Protein Radical Formation Resulting from Eosinophil Peroxidase-catalyzed Oxidation of Sulfite.
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| Ranguelova K, Chatterjee S, Ehrenshaft M, Ramirez DC, Summers FA, Kadiiska MB, Mason RP.
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| J Biol Chem 285(31):24195-205. doi: 10.1074/jbc.M109.069054. Epub 2010 May 25.
2010
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11 | EPX
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| Post-translational tyrosine nitration of eosinophil granule toxins mediated by eosinophil peroxidase.
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| Ulrich M, Petre A, Youhnovski N, Prömm F, Schirle M, Schumm M, Pero RS, Doyle A, Checkel J, Kita H, Thiyagarajan N, Acharya KR, Schmid-Grendelmeier P, Simon HU, Schwarz H, Tsutsui M, Shimokawa H, Bellon G, Lee JJ, Przybylski M, Döring G.
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| J Biol Chem 283(42):28629-40. doi: 10.1074/jbc.M801196200. Epub 2008 Aug 11.
2008
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12 | EPX, MPO
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| Thiocyanate modulates the catalytic activity of mammalian peroxidases.
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| Tahboub YR, Galijasevic S, Diamond MP, Abu-Soud HM.
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| J Biol Chem 280(28):26129-36. Epub 2005 May 13.
2005
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13 | EPX, EPXD
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| Human eosinophil peroxidase induces surface alteration, killing, and lysis of Mycobacterium tuberculosis.
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| Borelli V, Vita F, Shankar S, Soranzo MR, Banfi E, Scialino G, Brochetta C, Zabucchi G.
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| Infect Immun 71(2):605-13. 2003
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14 | EPX, LPO, MPO, EPXD
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| The eosinophil peroxidase gene forms a cluster with the genes for myeloperoxidase and lactoperoxidase on human chromosome 17.
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| Sakamaki K, Kanda N, Ueda T, Aikawa E, Nagata S.
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| Cytogenet Cell Genet 88(3-4):246-8. 2000
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15 | EPX
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| Molecular cloning and characterization of a chromosomal gene for human eosinophil peroxidase.
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| Sakamaki K, et al.
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| J Biol Chem 264 : 16828-16836. 1989
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