Citations for
1EPO, EPOR
Alternative Erythropoietin Receptors in the Nervous System.
Ostrowski D, Heinrich R.
J Clin Med 7(2). pii: E24. doi: 10.3390/jcm7020024. Review. 2018
2EPO, EPOR
Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.
Ueda F, Tago K, Tamura H, Funakoshi-Tago M.
J Biol Chem 292(5):1826-1846. doi: 10.1074/jbc.M116.749465. Epub 2016 Dec 20. 2017
3EPO, EPOR, FLT1
Erythropoietin accelerates tumor growth through increase of erythropoietin receptor (EpoR) as well as by the stimulation of angiogenesis in DLD-1 and Ht-29 xenografts.
Tankiewicz-Kwedlo A, Hermanowicz J, Surażynski A, Rożkiewicz D, Pryczynicz A, Domaniewski T, Pawlak K, Kemona A, Pawlak D.
Mol Cell Biochem 421(1-2):1-18. doi: 10.1007/s11010-016-2779-x. Epub 2016 Aug 20. 2016
4EPO, EPOR
Erythropoietin increases macrophage-mediated T cell suppression.
Wood MA, Goldman N, DePierri K, Somerville J, Riggs JE.
Cell Immunol 306-307:17-24. doi: 10.1016/j.cellimm.2016.05.004. Epub 2016 May 27. 2016
5EPO, EPOR
Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients.
Lamanuzzi A, Saltarella I, Ferrucci A, Ria R, Ruggieri S, Racanelli V, Rao L, Annese T, Nico B, Vacca A, Ribatti D.
Oncotarget 7(12):14510-21. doi: 10.18632/oncotarget.7587. 2016
6EPO, EPOR
Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance.
Luo B, Gan W, Liu Z, Shen Z, Wang J, Shi R, Liu Y, Liu Y, Jiang M, Zhang Z, Wu Y.
Immunity 44(2):287-302. doi: 10.1016/j.immuni.2016.01.002. Epub 2016 Feb 9. 2016
7ECYT1, EPOR
A new point mutation in EPOR inducing a short deletion in congenital erythrocytosis.
Chauveau A, Luque Paz D, Lecucq L, Le Gac G, Le Maréchal C, Gueguen P, Berthou C, Ugo V.
Br J Haematol 172(3):475-7. doi: 10.1111/bjh.13511. Epub 2015 May 26. No abstract available. 2016
8EPO, EPOR
In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain.
Suzuki N, Mukai HY, Yamamoto M.
PLoS One 10(3):e0119442. doi: 10.1371/journal.pone.0119442. eCollection 2015. 2015
9CSF2RB, EPOR
β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages.
Lee TS, Lu KY, Yu YB, Lee HT, Tsai FC.
Mediators Inflamm 2015:439759. doi: 10.1155/2015/439759. Epub 2015 May 25. 2015
10EPO, EPOR
The erythropoietin receptor is not required for the development, function, and aging of rods and cells in the retinal periphery.
Caprara C, Britschgi C, Samardzija M, Grimm C.
Mol Vis 20:307-24. eCollection 2014. 2014
11EPO, EPOR, VEGFA
VEGFA activates erythropoietin receptor and enhances VEGFR2-mediated pathological angiogenesis.
Yang Z, Wang H, Jiang Y, Hartnett ME.
Am J Pathol 184(4):1230-1239. doi: 10.1016/j.ajpath.2013.12.023. Epub 2014 Mar 12. 2014
12CBL, EPO, EPOR, PIK3R1
Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.
Bulut GB, Sulahian R, Yao H, Huang LJ.
Blood 122(24):3964-72. doi: 10.1182/blood-2013-05-506212. Epub 2013 Oct 10. 2013
13EPO, EPOR
Erythropoietin (EPO) increases myelin gene expression in CG4 oligodendrocyte cells through the classical EPO receptor.
Cervellini I, Annenkov A, Brenton T, Chernajovsky Y, Ghezzi P, Mengozzi M.
Mol Med 19:223-9. doi: 10.2119/molmed.2013.00013. 2013
14EPOR, SP1
Changes in the Expression of Transcription Factors Involved in Modulating the Expression of EPO-R in Activated Human CD4-Positive Lymphocytes.
Lisowska KA, Frackowiak JE, Mikosik A, Witkowski JM.
PLoS One 8(4):e60326. doi: 10.1371/journal.pone.0060326. Epub 2013 Apr 5. 2013
15EPO, EPOR, JAK2, SH2B1
The SH2B1 adaptor protein associates with a proximal region of the erythropoietin receptor.
Javadi M, Hofstätter E, Stickle N, Beattie BK, Jaster R, Carter-Su C, Barber DL.
J Biol Chem 287(31):26223-34. doi: 10.1074/jbc.M112.382721. Epub 2012 Jun 5. 2012
16EPOR, GATA1, GATA2, LDB1, TAL1
T-cell acute leukemia 1 (TAL1) regulation of erythropoietin receptor and association with excessive erythrocytosis.
Rogers H, Wang L, Yu X, Alnaeeli M, Cui K, Zhao K, Bieker JJ, Prchal J, Huang S, Weksler B, Noguchi CT.
J Biol Chem 287(44):36720-31. doi: 10.1074/jbc.M112.378398. Epub 2012 Sep 16. 2012
17EPO, EPOR
Emergence of the Erythropoietin/Erythropoietin Receptor System as a Novel Cardiovascular Therapeutic Target.
Satoh K, Fukumoto Y, Nakano M, Kagaya Y, Shimokawa H.
J Cardiovasc Pharmacol Cardiovasc Pharmacol. 2011 Sep 20. [Epub ahead of print] 2011
18EPO, EPOR
Erythropoietin receptor contributes to melanoma cell survival in vivo.
Kumar SM, Zhang G, Bastian BC, Arcasoy MO, Karande P, Pushparajan A, Acs G, Xu X.
Oncogene ncogene. 2011 Aug 22. doi: 10.1038/onc.2011.366. [Epub ahead of print] 2011
19EPO, EPOR
The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression.
Hedley BD, Allan AL, Xenocostas A.
Clin Cancer Res 17(20):6373-80. Epub 2011 Jul 12. 2011
20EPO, EPOR
Erythropoietin: a hormone with multiple functions.
Lombardero M, Kovacs K, Scheithauer BW.
Pathobiology 78(1):41-53. Epub 2011 Apr 5. Review. 2011
21EPOR
Erythropoietin receptor is detectable on peripheral blood lymphocytes and its expression increases in activated T lymphocytes.
Lisowska KA, Bryl E, Witkowski JM.
Haematologica 96(3):e12-3; author reply e14. No abstract available. 2011
22EPOR, GATA4
Gata4 and Sp1 regulate expression of the erythropoietin receptor in cardiomyocytes.
Salisch S, Klar M, Thurisch B, Bungert J, Dame C.
J Cell Mol Med 15(9):1963-72. doi: 10.1111/j.1582-4934.2010.01193.x. 2011
23EPOR
Cytosolic lysine residues enhance anterograde transport and activation of the erythropoietin receptor.
Yosha L, Ravid O, Ben-Califa N, Neumann D.
Biochem J 435(2):509-18. 2011
24EPO, EPOR, GDF15, TFR2
Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.
Forejtnikovà H, Vieillevoye M, Zermati Y, Lambert M, Pellegrino RM, Guihard S, Gaudry M, Camaschella C, Lacombe C, Roetto A, Mayeux P, Verdier F.
Blood 116(24):5357-67. Epub 2010 Sep 8. 2010
25EPO, EPOR
Up-regulation of erythropoietin receptor by nitric oxide mediates hypoxia preconditioning.
Chen ZY, Wang L, Asavaritkrai P, Noguchi CT.
J Neurosci Res 88(14):3180-8. 2010
26EPO, EPOR
Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance.
Cao Y, Lathia JD, Eyler CE, Wu Q, Li Z, Wang H, McLendon RE, Hjelmeland AB, Rich JN.
Genes Cancer 1(1):50-61. 2010
27EPO, EPOR
Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease.
Khankin EV, Mutter WP, Tamez H, Yuan HT, Karumanchi SA, Thadhani R.
PLoS One 5(2):e9246. 2010
28EPO, EPOR
Erythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo.
Huang X, Pierce LJ, Chen GL, Chang KT, Spangrude GJ, Prchal JT.
Blood Cells Mol Dis 44(1):1-6. Epub 2009 Oct 17. 2010
29ECYT1, ECYT2, ECYT3, ECYT4, EGLN1, EPAS1, EPOR, VHL
Genetic origins and clinical phenotype of familial and acquired erythrocytosis and thrombocytosis.
Percy MJ, Rumi E.
Am J Hematol 84(1):46-54. Review. 2009
30EPO, EPOR
Molecular basis of cardioprotection by erythropoietin.
Burger D, Xenocostas A, Feng QP.
Curr Mol Pharmacol 2(1):56-69. Review. 2009
31EPO, EPOR, VEGFA
Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear.
Monge Naldi A, Gassmann M, Bodmer D.
Cell Mol Life Sci 66(22):3595-9. Epub 2009 Sep 10. Review. 2009
32ECYT1, ECYT2, ECYT3, ECYT4, EGLN1, EPAS1, EPOR, VHL
A study of 36 unrelated cases with pure erythrocytosis revealed three new mutations in the erythropoietin receptor gene.
Al-Sheikh M, Mazurier E, Gardie B, Casadevall N, Galactéros F, Goossens M, Wajcman H, Préhu C, Ugo V.
Haematologica 93(7):1072-5. Epub 2008 May 19. 2008
33CALM1, EPOR, JAK2
Calmodulin physically interacts with the erythropoietin receptor and enhances Jak2-mediated signaling.
Kakihana K, Yamamoto M, Iiyama M, Miura O.
Biochem Biophys Res Commun 335(2):424-31. 2005
34MST1R, EPOR
Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors.
van den Akker E, van Dijk T, Parren-van Amelsvoort M, Grossmann KS, Schaeper U, Toney-Earley K, Waltz SE, Lowenberg B, von Lindern M.
Blood 103(12):4457-65. Epub 2004 Feb 24. 2004
35EPOR, STAT1, STAT3, STAT5A
Identification of the human erythropoietin receptor region required for Stat1 and Stat3 activation.
Kirito K, Nakajima K, Watanabe T, Uchida M, Tanaka M, Ozawa K, Komatsu N.
Blood 99(1):102-10. 2002
36EPOR, SOCS3
A new high affinity binding site for suppressor of cytokine signaling-3 on the erythropoietin receptor.
Hortner M, Nielsch U, Mayr LM, Heinrich PC, Haan S.
Eur J Biochem 269(10):2516-26. 2002
37EPOR
Erythropoietin and erythropoietin receptor expression in human endometrium throughout the menstrual cycle.
Yokomizo R, Matsuzaki S, Uehara S, Murakami T, Yaegashi N, Okamura K.
Mol Hum Reprod 8(5):441-6. 2002
38EPOR
A human erythropoietin receptor gene mutant causing familial erythrocytosis is associated with deregulation of the rates of Jak2 and Stat5 inactivation.
Arcasoy MO, et al.
Exp Hematol 27(1):63-74. 1999
39EPO, EPOR
Human, rat, and mouse kidney cells express functional erythropoietin receptors.
Westenfelder C, et al.
Kidney Int 55(3):808-20. 1999
40EPOR, EPO
Identification of the erythropoietin receptor domain required for calcium channel activation.
Miller BA, et al.
J Biol Chem 274(29):20465-72 1999
41ECYT1, EPOR
Erythrocytosis due to a mutation in the erythropoietin receptor gene.
Percy MJ, McMullin MF, Roques AW, Westwood NB, Acharya J, Hughes AE, Lappin TR, Pearson TC.
Br J Haematol 100(2):407-10. 1998
42ECYT1, EPOR
Absence of polycythemia in a child with a unique erythropoietin receptor mutation in a family with autosomal dominant primary polycythemia.
Kralovics R, et al.
J Clin Invest 102 : 124-129. 1998
43ECYT1, EPOR
Familial erythrocytosis associated with a short deletion in the erythropoietin receptor gene.
Arcasoy MO, Degar BA, Harris KW, Forget BG.
Blood 89(12):4628-35. 1997
44ECYT1, EPOR
Two new EPO receptor mutations: truncated EPO receptors are most frequently associated with primary familial and congenital polycythemias.
Kralovics R, Indrak K, Stopka T, Berman BW, Prchal JF, Prchal JT.
Blood 90(5):2057-61. 1997
45ECYT1, EPOR
Primary familial polycythaemia associated with a novel point mutation in the erythropoietin receptor.
Furukawa T, et al.
Br J Haematol 99 : 222-227. 1997
46CYP2B, CYP2B6, CYP2B7P1, CYP2F1, EPOR, HERVK10T, JAK3, RRAS, ZNF134, ZNF14, ZNF44, ZNF91, ZNF97
Positioning of 72 potentially full size LTRs of human endogenous retroviruses HERV-K on the human chromosome 19 map. Occurrences of the LTRs in human gene sites.
Vinogradova T, Volik S, Lebedev Y, Shevchenko Y, Lavrentyeva I, Khil P, Grzeschik KH, Ashworth LK, Sverdlov E.
Gene 199(1-2):255-64. 1997
47EPOR
Mutations in the erythropoietin receptor gene are not a common cause of Diamond-Blackfan anemia.
Dianzani I, et al.
Blood 87 : 2568-2572. 1996
48ECYT1, EPOR
Primary familial polycythemia : a frameshift mutation in the erythropoietin receptor gene and increased sensitivity of erythroid progenitors to erythropoietin.
Sikol L, et al.
Blood 86 : 15-22. 1995
49EPOR
Two microsatellite repeat polymorphisms in the EPO gene.
Sokol L, et al.
Hum Mol Genet 3 : 219. 1994
50EPOR
Dinucleotide repeat polymorphism at the human erythropoietin receptor locus (EPOR) at 19p13.
McDonald MT, et al.
Hum Mol Genet 2 : 619. 1993
51ECYT1, EPOR
Truncated erythropoietin receptor causes dominantly inherited benign human erythrocytosis.
de la Chapelle A, et al.
Proc Natl Acad Sci U S A 90 : 4495-4499. 1993
52EPOR
Genetic mapping of the erythropoietin receptor gene.
Sistonen P, et al.
Hum Genet 92 : 299-301. 1993
53ECYT1, EPOR
Familial erythrocytosis genetically linked to erythropoietin receptor gene.
de La Chapelle A, et al.
Lancet 341 : 82-84. 1993
54EPOR
Autosomal dominant erythrocytosis caused by increased sensitivity to erythropoietin.
Juvonen E, et al.
Blood 78 : 3066-3069. 1991
55EPOR
Human erythropoietin receptor : cloning, expression, and biologic characterization.
Jones SS, et al.
Blood 76 : 31-35. 1990
56EPOR
The gene for the human erythropoietin receptor: analysis of the coding sequence and assignment to chromosome 19p.
Winkelmann JC, et al.
Blood 76 : 24-30. 1990
57EPOR
Point mutation in the exoplasmic domain of the erythropoietin receptor resulting in hormone-independent activation and tumorigenicity.
Yoshimura A, et al.
Nature 348 : 647-649. 1990