| 1 | EPO, EPOR
|
| Alternative Erythropoietin Receptors in the Nervous System.
|
| Ostrowski D, Heinrich R.
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| J Clin Med 7(2). pii: E24. doi: 10.3390/jcm7020024. Review.
2018
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| 2 | CSFR2B, EPO
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| EPO does not promote interaction between the erythropoietin and beta-common receptors.
|
| Cheung Tung Shing KS, Broughton SE, Nero TL, Gillinder K, Ilsley MD, Ramshaw H, Lopez AF, Griffin MDW, Parker MW, Perkins AC, Dhagat U.
|
| Sci Rep 8(1):12457. doi: 10.1038/s41598-018-29865-x. Erratum in: Sci Rep. 2019 May 21;9(1):7851.
2018
|
| 3 | CRLF3, EPO
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| The Insect Ortholog of the Human Orphan Cytokine Receptor CRLF3 Is a Neuroprotective Erythropoietin Receptor.
|
| Hahn N, Knorr DY, Liebig J, Wüstefeld L, Peters K, Büscher M, Bucher G, Ehrenreich H, Heinrich R.
|
| Front Mol Neurosci 10:223. doi: 10.3389/fnmol.2017.00223. eCollection 2017.
2017
|
| 4 | EPO, EPOR
|
| Three Tyrosine Residues in the Erythropoietin Receptor Are Essential for Janus Kinase 2 V617F Mutant-induced Tumorigenesis.
|
| Ueda F, Tago K, Tamura H, Funakoshi-Tago M.
|
| J Biol Chem 292(5):1826-1846. doi: 10.1074/jbc.M116.749465. Epub 2016 Dec 20.
2017
|
| 5 | EPO, EPOR, FLT1
|
| Erythropoietin accelerates tumor growth through increase of erythropoietin receptor (EpoR) as well as by the stimulation of angiogenesis in DLD-1 and Ht-29 xenografts.
|
| Tankiewicz-Kwedlo A, Hermanowicz J, Surażynski A, Rożkiewicz D, Pryczynicz A, Domaniewski T, Pawlak K, Kemona A, Pawlak D.
|
| Mol Cell Biochem 421(1-2):1-18. doi: 10.1007/s11010-016-2779-x. Epub 2016 Aug 20.
2016
|
| 6 | EPO, EPOR
|
| Erythropoietin increases macrophage-mediated T cell suppression.
|
| Wood MA, Goldman N, DePierri K, Somerville J, Riggs JE.
|
| Cell Immunol 306-307:17-24. doi: 10.1016/j.cellimm.2016.05.004. Epub 2016 May 27.
2016
|
| 7 | EPO, EPOR
|
| Role of erythropoietin in the angiogenic activity of bone marrow endothelial cells of MGUS and multiple myeloma patients.
|
| Lamanuzzi A, Saltarella I, Ferrucci A, Ria R, Ruggieri S, Racanelli V, Rao L, Annese T, Nico B, Vacca A, Ribatti D.
|
| Oncotarget 7(12):14510-21. doi: 10.18632/oncotarget.7587.
2016
|
| 8 | EPO, EPOR
|
| Erythropoeitin Signaling in Macrophages Promotes Dying Cell Clearance and Immune Tolerance.
|
| Luo B, Gan W, Liu Z, Shen Z, Wang J, Shi R, Liu Y, Liu Y, Jiang M, Zhang Z, Wu Y.
|
| Immunity 44(2):287-302. doi: 10.1016/j.immuni.2016.01.002. Epub 2016 Feb 9.
2016
|
| 9 | EPO, EPOR
|
| In vivo regulation of erythropoiesis by chemically inducible dimerization of the erythropoietin receptor intracellular domain.
|
| Suzuki N, Mukai HY, Yamamoto M.
|
| PLoS One 10(3):e0119442. doi: 10.1371/journal.pone.0119442. eCollection 2015.
2015
|
| 10 | CCL3, EPO
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| Erythropoietin and CCL3 antagonise their functional properties during neuroinflammation.
|
| Hattermann K, Knerlich-Lukoschus F, Lucius R, Mehdorn M, Held-Feindt J.
|
| Neurol Res 37(11):1025-8. doi: 10.1179/1743132815Y.0000000070. Epub 2015 Jul 16.
2015
|
| 11 | EPO, EPOR
|
| The erythropoietin receptor is not required for the development, function, and aging of rods and cells in the retinal periphery.
|
| Caprara C, Britschgi C, Samardzija M, Grimm C.
|
| Mol Vis 20:307-24. eCollection 2014.
2014
|
| 12 | EPO, EPOR, VEGFA
|
| VEGFA activates erythropoietin receptor and enhances VEGFR2-mediated pathological angiogenesis.
|
| Yang Z, Wang H, Jiang Y, Hartnett ME.
|
| Am J Pathol 184(4):1230-1239. doi: 10.1016/j.ajpath.2013.12.023. Epub 2014 Mar 12.
2014
|
| 13 | CBL, EPO, EPOR, PIK3R1
|
| Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.
|
| Bulut GB, Sulahian R, Yao H, Huang LJ.
|
| Blood 122(24):3964-72. doi: 10.1182/blood-2013-05-506212. Epub 2013 Oct 10.
2013
|
| 14 | EPO, EPOR
|
| Erythropoietin (EPO) increases myelin gene expression in CG4 oligodendrocyte cells through the classical EPO receptor.
|
| Cervellini I, Annenkov A, Brenton T, Chernajovsky Y, Ghezzi P, Mengozzi M.
|
| Mol Med 19:223-9. doi: 10.2119/molmed.2013.00013.
2013
|
| 15 | EPO
|
| Erythropoietin improves memory function with reducing endothelial dysfunction and amyloid-beta burden in Alzheimer's disease models.
|
| Lee ST, Chu K, Park JE, Jung KH, Jeon D, Lim JY, Lee SK, Kim M, Roh JK.
|
| J Neurochem 120(1):115-24. doi: 10.1111/j.1471-4159.2011.07534.x. Epub 2011 Nov 11.
2012
|
| 16 | EPO, FN1
|
| The association between RhEPO and FN expression in glomerular mesangial cells.
|
| Zhou SQ, Wen P, Fang L, Jiang L, Xiong M, Zhang FF, Yang JW.
|
| Panminerva Med 54(3):205-9.
2012
|
| 17 | EPO, EPOR, JAK2, SH2B1
|
| The SH2B1 adaptor protein associates with a proximal region of the erythropoietin receptor.
|
| Javadi M, Hofstätter E, Stickle N, Beattie BK, Jaster R, Carter-Su C, Barber DL.
|
| J Biol Chem 287(31):26223-34. doi: 10.1074/jbc.M112.382721. Epub 2012 Jun 5.
2012
|
| 18 | EPO, GATA4, SIRT1, TAL1
|
| GATA-binding protein 4 (GATA-4) and T-cell acute leukemia 1 (TAL1) regulate myogenic differentiation and erythropoietin response via cross-talk with Sirtuin1 (Sirt1).
|
| Wang L, Jia Y, Rogers H, Wu YP, Huang S, Noguchi CT.
|
| J Biol Chem 287(36):30157-69. doi: 10.1074/jbc.M112.376640. Epub 2012 Jul 7.
2012
|
| 19 | EPO
|
| Nonviral gene delivery of erythropoietin by mesenchymal stromal cells.
|
| Scheibe F, Gladow N, Mergenthaler P, Tucker AH, Meisel A, Prockop DJ, Priller J.
|
| Gene Ther ene Ther. 2011 Sep 29. doi: 10.1038/gt.2011.139. [Epub ahead of print]
2011
|
| 20 | EPO, EPOR
|
| Emergence of the Erythropoietin/Erythropoietin Receptor System as a Novel Cardiovascular Therapeutic Target.
|
| Satoh K, Fukumoto Y, Nakano M, Kagaya Y, Shimokawa H.
|
| J Cardiovasc Pharmacol Cardiovasc Pharmacol. 2011 Sep 20. [Epub ahead of print]
2011
|
| 21 | EPO
|
| Polymorphism of the erythropoietin gene promotor and the development of myelodysplastic syndromes subsequent to multiple myeloma.
|
| Landgren O, Ma W, Kyle RA, Rajkumar SV, Korde N, Albitar M.
|
| Leukemia eukemia. 2011 Sep 16. doi: 10.1038/leu.2011.262. [Epub ahead of print] No abstract available.
2011
|
| 22 | EPO, MTOR
|
| Erythropoietin mediated bone formation is regulated by mTOR signaling.
|
| Kim J, Jung Y, Sun H, Joseph J, Mishra A, Shiozawa Y, Wang J, Krebsbach PH, Taichman RS.
|
| J Cell Biochem Cell Biochem. 2011 Sep 6. doi: 10.1002/jcb.23347. [Epub ahead of print]
2011
|
| 23 | EPO, EPOR
|
| Erythropoietin receptor contributes to melanoma cell survival in vivo.
|
| Kumar SM, Zhang G, Bastian BC, Arcasoy MO, Karande P, Pushparajan A, Acs G, Xu X.
|
| Oncogene ncogene. 2011 Aug 22. doi: 10.1038/onc.2011.366. [Epub ahead of print]
2011
|
| 24 | EPO, EPOR
|
| The role of erythropoietin and erythropoiesis-stimulating agents in tumor progression.
|
| Hedley BD, Allan AL, Xenocostas A.
|
| Clin Cancer Res 17(20):6373-80. Epub 2011 Jul 12.
2011
|
| 25 | EPO
|
| The extra-hematopoietic role of erythropoietin in diabetes mellitus.
|
| Choi D, Retnakaran R, Woo M.
|
| Curr Diabetes Rev 7(4):284-90.
2011
|
| 26 | EPO, EPOR
|
| Erythropoietin: a hormone with multiple functions.
|
| Lombardero M, Kovacs K, Scheithauer BW.
|
| Pathobiology 78(1):41-53. Epub 2011 Apr 5. Review.
2011
|
| 27 | EPO
|
| The erythropoietin receptor: molecular structure and hematopoietic signaling pathways.
|
| Watowich SS.
|
| J Investig Med 59(7):1067-72.
2011
|
| 28 | CSF3, EPO
|
| Erythropoietin combined with granulocyte colony‑stimulating factor enhances MMP-2 expression in mesenchymal stem cells and promotes cell migration.
|
| Yu Q, Chen L, You Y, Zou C, Zhang Y, Liu Q, Cheng F.
|
| Mol Med Rep 4(1):31-6. doi: 10.3892/mmr.2010.387.
2011
|
| 29 | CSF2RB, EPO
|
| β Common receptor integrates the erythropoietin signaling in activation of endothelial nitric oxide synthase.
|
| Su KH, Shyue SK, Kou YR, Ching LC, Chiang AN, Yu YB, Chen CY, Pan CC, Lee TS.
|
| J Cell Physiol 226(12):3330-9. doi: 10.1002/jcp.22678.
2011
|
| 30 | EPO, EPOR, GDF15, TFR2
|
| Transferrin receptor 2 is a component of the erythropoietin receptor complex and is required for efficient erythropoiesis.
|
| Forejtnikovà H, Vieillevoye M, Zermati Y, Lambert M, Pellegrino RM, Guihard S, Gaudry M, Camaschella C, Lacombe C, Roetto A, Mayeux P, Verdier F.
|
| Blood 116(24):5357-67. Epub 2010 Sep 8.
2010
|
| 31 | EPO
|
| Erythropoietin protects against diabetes through direct effects on pancreatic beta cells.
|
| Choi D, Schroer SA, Lu SY, Wang L, Wu X, Liu Y, Zhang Y, Gaisano HY, Wagner KU, Wu H, Retnakaran R, Woo M.
|
| J Exp Med 207(13):2831-42. Epub 2010 Dec 13.
2010
|
| 32 | EPO
|
| Cardiovascular effects of erythropoietin an update.
|
| Santhanam AV, d'Uscio LV, Katusic ZS.
|
| Adv Pharmacol 60:257-85. Review.
2010
|
| 33 | EPO, EPOR
|
| Up-regulation of erythropoietin receptor by nitric oxide mediates hypoxia preconditioning.
|
| Chen ZY, Wang L, Asavaritkrai P, Noguchi CT.
|
| J Neurosci Res 88(14):3180-8.
2010
|
| 34 | EPO, EPOR
|
| Erythropoietin Receptor Signaling Through STAT3 Is Required For Glioma Stem Cell Maintenance.
|
| Cao Y, Lathia JD, Eyler CE, Wu Q, Li Z, Wang H, McLendon RE, Hjelmeland AB, Rich JN.
|
| Genes Cancer 1(1):50-61.
2010
|
| 35 | EPO
|
| Macrophages as novel target cells for erythropoietin.
|
| Lifshitz L, Tabak G, Gassmann M, Mittelman M, Neumann D.
|
| Haematologica 95(11):1823-31. Epub 2010 Jun 30.
2010
|
| 36 | EPO
|
| Erythropoietin couples hematopoiesis with bone formation.
|
| Shiozawa Y, Jung Y, Ziegler AM, Pedersen EA, Wang J, Wang Z, Song J, Wang J, Lee CH, Sud S, Pienta KJ, Krebsbach PH, Taichman RS.
|
| PLoS One 5(5):e10853.
2010
|
| 37 | EPO, EPOR
|
| Soluble erythropoietin receptor contributes to erythropoietin resistance in end-stage renal disease.
|
| Khankin EV, Mutter WP, Tamez H, Yuan HT, Karumanchi SA, Thadhani R.
|
| PLoS One 5(2):e9246.
2010
|
| 38 | EPO
|
| Erythropoietin concentration in serum and cerebrospinal fluid of patients with amyotrophic lateral sclerosis.
|
| Janik P, Kwiecinski H, Sokolowska B, Niebroj-Dobosz I.
|
| J Neural Transm 117(3):343-7. Epub 2009 Dec 12.
2010
|
| 39 | EPO, EPOR
|
| Erythropoietin receptor signaling regulates both erythropoiesis and megakaryopoiesis in vivo.
|
| Huang X, Pierce LJ, Chen GL, Chang KT, Spangrude GJ, Prchal JT.
|
| Blood Cells Mol Dis 44(1):1-6. Epub 2009 Oct 17.
2010
|
| 40 | EPO, EPOR
|
| Molecular basis of cardioprotection by erythropoietin.
|
| Burger D, Xenocostas A, Feng QP.
|
| Curr Mol Pharmacol 2(1):56-69. Review.
2009
|
| 41 | EPO
|
| Erythropoietin in amyotrophic lateral sclerosis: a pilot, randomized, double-blind, placebo-controlled study of safety and tolerability.
|
| Lauria G, Campanella A, Filippini G, Martini A, Penza P, Maggi L, Antozzi C, Ciano C, Beretta P, Caldiroli D, Ghelma F, Ferrara G, Ghezzi P, Mantegazza R.
|
| Amyotroph Lateral Scler 10(5-6):410-5.
2009
|
| 42 | EPO, EPOR, VEGFA
|
| Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear.
|
| Monge Naldi A, Gassmann M, Bodmer D.
|
| Cell Mol Life Sci 66(22):3595-9. Epub 2009 Sep 10. Review.
2009
|
| 43 | EPO
|
| Neuroprotection of photoreceptors by direct delivery of erythropoietin to the retina of the retinal degeneration slow mouse.
|
| Rex TS, Wong Y, Kodali K, Merry S.
|
| Exp Eye Res 89(5):735-40. Epub 2009 Jul 8.
2009
|
| 44 | EPO, VEGFA, NGF, ANG
|
| Neurovascular signalling defects in neurodegeneration.
|
| Zacchigna S, Lambrechts D, Carmeliet P.
|
| Nat Rev Neurosci 9(3):169-81. 2008
|
| 45 | EPO
|
| Promoter polymorphism of the erythropoietin gene in severe diabetic eye and kidney complications.
|
| Tong Z, Yang Z, Patel S, Chen H, Gibbs D, Yang X, Hau VS, Kaminoh Y, Harmon J, Pearson E, Buehler J, Chen Y, Yu B, Tinkham NH, Zabriskie NA, Zeng J, Luo L, Sun JK, Prakash M, Hamam RN, Tonna S, Constantine R, Ronquillo CC, Sadda S, Avery RL, Brand JM, London N, Anduze AL, King GL, Bernstein PS, Watkins S; Genetics of Diabetes and Diabetic Complication Study Group, Jorde LB, Li DY, Aiello LP, Pollak MR, Zhang K.
|
| Proc Natl Acad Sci U S A 105(19):6998-7003. Epub 2008 May 5. 2008
|
| 46 | EPO, TRPC3
|
| TRPC3 is the erythropoietin-regulated calcium channel in human erythroid cells.
|
| Tong Q, Hirschler-Laszkiewicz I, Zhang W, Conrad K, Neagley DW, Barber DL, Cheung JY, Miller BA.
|
| J Biol Chem 283(16):10385-95. Epub 2008 Feb 14.
2008
|
| 47 | EPO
|
| Erythropoietin enhances hippocampal response during memory retrieval in humans.
|
| Miskowiak K, O'Sullivan U, Harmer CJ.
|
| J Neurosci 27(11):2788-92. 2007
|
| 48 | EPO, IL3, KITLG
|
| Synergistic effect of cytokines EPO, IL-3 and SCF on the proliferation, differentiation and apoptosis of erythroid progenitor cells.
|
| Wang J, Tang ZY, Ka W, Sun D, Yao W, Wen Z, Chien S.
|
| Clin Hemorheol Microcirc 37(4):291-9.
2007
|
| 49 | VEGFA, EPO
|
| VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis.
|
| Tam BY, Wei K, Rudge JS, Hoffman J, Holash J, Park SK, Yuan J, Hefner C, Chartier C, Lee JS, Jiang S, Niyak NR, Kuypers FA, Ma L, Sundram U, Wu G, Garcia JA, Schrier SL, Maher JJ, Johnson RS, Yancopoulos GD, Mulligan RC, Kuo CJ.
|
| Nat Med 12(7):793-800. Epub 2006 Jun 25. 2006
|
| 50 | EPO,IL1A
|
| Erythropoietin production: Molecular mechanisms of the antagonistic actions of cyclic adenosine monophosphate and interleukin-1.
|
| Batmunkh C, Krajewski J, Jelkmann W, Hellwig-Burgel T.
|
| FEBS Lett 580(13):3153-60. Epub 2006 May 2. 2006
|
| 51 | THPO, EPO
|
| A hematopoietic growth factor, thrombopoietin, has a proapoptotic role in the brain.
|
| Ehrenreich H, Hasselblatt M, Knerlich F, von Ahsen N, Jacob S, Sperling S, Woldt H, Vehmeyer K, Nave KA, Siren AL.
|
| Proc Natl Acad Sci U S A 102(3):862-7. Epub 2005 Jan 10. 2005
|
| 52 | EPO
|
| Erythropoietin gene expression in different areas of the developing human central nervous system.
|
| Dame C, Bartmann P, Wolber E, Fahnenstich H, Hofmann D, Fandrey J.
|
| Brain Res Dev Brain Res 125(1-2):69-74. 2000
|
| 53 | EPO, EPOR
|
| Human, rat, and mouse kidney cells express functional erythropoietin receptors.
|
| Westenfelder C, et al.
|
| Kidney Int 55(3):808-20. 1999
|
| 54 | EPOR, EPO
|
| Identification of the erythropoietin receptor domain required for calcium channel activation.
|
| Miller BA, et al.
|
| J Biol Chem 274(29):20465-72 1999
|
| 55 | ACTL6B, AGFG2, CUX1, EPO, GIGYF1, GNB2, IRS3L, LRCH4, PCOLCE, RELN, SH2B2, TFR2
|
| Large-scale sequencing of two regions in human chromosome 7q22 : analysis of 650kb of genomic sequence around the EPO and CUTL1 loci reveals 17 genes.
|
| Glockner G, Scherer S, Schattevoy R, Boright A, Weber J, Tsui LC, Rosenthal A.
|
| Genome Res 8 : 1060-1073. 1998
|
| 56 | EPO
|
| Sequence analysis of the 3' hypoxia-responsive element of the human erythropoietin gene in patients with erythrocytosis.
|
| Percy MJ, McMullin MF, Lappin TR.
|
| Biochem Mol Med 62(1):132-4. 1997
|
| 57 | EPO, LPO, MPO
|
| Molecular cloning and characterization of the chromosomal gene for human lactoperoxidase.
|
| Ueda T, Sakamaki K, Kuroki T, Yano I, Nagata S.
|
| Eur J Biochem 243(1-2):32-41. 1997
|
| 58 | COL1A2, EPO, GNB2
|
| Construction of human chromosome 7 YAC contigs around the COL1A2 and EPO genes and mapping of the GNB2 gene.
|
| Kere J, et al.
|
| (HGM11) Cytogenet Cell Genet 58 : 1922-1923. 1991
|
| 59 | EPO
|
| BgIII polymorphism at the human erythropoietin gene.
|
| Beru N, et al.
|
| Nucleic Acids Res 19 : 1717. 1991
|
| 60 | EPO, LAMB1, PDGFA
|
| Mapping PDGFA, EPO, and LAMB1 to specific sites on chromosome 7q.
|
| Fukushima Y, et al.
|
| (HGM9) Cytogenet Cell Genet 46 : 616. 1987
|
| 61 | EPO
|
| An Xba I polymorphism 3' to the human erythropoietin (EPO) gene.
|
| Semenza GL, et al.
|
| Nucleic Acids Res 15 : 6768. 1987
|
| 62 | EPO
|
| Chromosomal assignment of the human erythropoietin gene and its DNA polymorphism.
|
| Law ML, et al.
|
| Proc Natl Acad Sci U S A 83 : 6920-6924. 1986
|
| 63 | EPO
|
| Regional assignment of the erythropoietin gene to human chromosome region 7pter-q22.
|
| Watkins PC, et al.
|
| Cytogenet Cell Genet 42 : 214-218. 1986
|
| 64 | EPO
|
| Chromosomal sublocalization of the human erythropoietin gene.
|
| Le Beau MM, et al.
|
| Blood 66 :155A. 1985
|
| 65 | EPO
|
| Chromosome localization of the gen for human erythropoietin and high level expression of cloned genomic sequences in permanent mammalian cell lines.
|
| Powell JS, et al.
|
| Blood 66 : 159A. 1985
|