Citations for
1EPHB2, SPSB4
Ubiquitin ligase SPSB4 diminishes cell repulsive responses mediated by EphB2.
Okumura F, Joo-Okumura A, Obara K, Petersen A, Nishikimi A, Fukui Y, Nakatsukasa K, Kamura T.
Mol Biol Cell. Nov 15;28(24):3532-3541. doi: 10.1091/mbc.E17-07-0450. Epub 2017 Sep 20 2017
2CDC42, EPHB2, PAK3
Regulation of AMPA receptor subunit GluA1 surface expression by PAK3 phosphorylation.
Hussain NK, Thomas GM, Luo J, Huganir RL.
Proc Natl Acad Sci U S A 112(43):E5883-90. doi: 10.1073/pnas.1518382112. Epub 2015 Oct 12. 2015
3EPHB2, EPHB4
The differential expression of EphB2 and EphB4 receptor kinases in normal bladder and in transitional cell carcinoma of the bladder.
Li X, Choi WW, Yan R, Yu H, Krasnoperov V, Kumar SR, Schuckman A, Klumpp DJ, Pan CX, Quinn D, Gill IS, Gill PS, Liu R.
PLoS One 9(8):e105326. doi: 10.1371/journal.pone.0105326. eCollection 2014. 2014
4EPHB2, EPHB4
Ephrin B2 and EphB4 selectively mark arterial and venous vessels in cerebral arteriovenous malformation.
Bai J, Wang YJ, Liu L, Zhao YL.
J Int Med Res 42(2):405-15. doi: 10.1177/0300060513478091. Epub 2014 Feb 11. 2014
5EPHB1, EPHB2, RELN
Reelin induces EphB activation.
Bouché E, Romero-Ortega MI, Henkemeyer M, Catchpole T, Leemhuis J, Frotscher M, May P, Herz J, Bock HH.
Cell Res 23(4):473-90. doi: 10.1038/cr.2013.7. Epub 2013 Jan 15. 2013
6EPHB2, KLK8
Neuropsin cleaves EphB2 in the amygdala to control anxiety.
Attwood BK, Bourgognon JM, Patel S, Mucha M, Schiavon E, Skrzypiec AE, Young KW, Shiosaka S, Korostynski M, Piechota M, Przewlocki R, Pawlak R.
Nature 473(7347):372-5. Epub 2011 Apr 20. 2011
7EPHB1, EPHB2
EphB-ephrin-B2 interactions are required for thymus migration during organogenesis.
Foster KE, Gordon J, Cardenas K, Veiga-Fernandes H, Makinen T, Grigorieva E, Wilkinson DG, Blackburn CC, Richie E, Manley NR, Adams RH, Kioussis D, Coles MC.
Proc Natl Acad Sci U S A 107(30):13414-9. Epub 2010 Jul 8.PMID: 20616004 2010
8EPHB2, EPHB3
Trans-synaptic EphB2-ephrin-B3 interaction regulates excitatory synapse density by inhibition of postsynaptic MAPK signaling.
McClelland AC, Hruska M, Coenen AJ, Henkemeyer M, Dalva MB.
Proc Natl Acad Sci U S A 107(19):8830-5. Epub 2010 Apr 21. 2010
9EPHB2, EPHB3
Ephrinb3 induces mesostriatal dopaminergic projection to the striatum.
Sun JH, Gao Q, Zhang J, Bao LH, Dong HM, Liang N, Li GB, Li ZH, Gao YM.
Biochem Biophys Res Commun 400(2):194-9. Epub 2010 Aug 16. 2010
10EPHB2
Dissociation of EphB2 signaling pathways mediating progenitor cell proliferation and tumor suppression.
Genander M, Halford MM, Xu NJ, Eriksson M, Yu Z, Qiu Z, Martling A, Greicius G, Thakar S, Catchpole T, Chumley MJ, Zdunek S, Wang C, Holm T, Goff SP, Pettersson S, Pestell RG, Henkemeyer M, Frisén J.
Cell 139(4):679-92.PMID: 19914164 2009
11EPHB2, EPHB3
Cell-autonomous role of EphB2 and EphB3 receptors in the thymic epithelial cell organization.
García-Ceca J, Jiménez E, Alfaro D, Cejalvo T, Muñoz JJ, Zapata AG.
Eur J Immunol 39(10):2916-24. 2009
12EPHB2, EPHB3
On the role of Eph signalling in thymus histogenesis; EphB2/B3 and the organizing of the thymic epithelial network.
García-Ceca J, Jiménez E, Alfaro D, Cejalvo T, Chumley MJ, Henkemeyer M, Muñoz JJ, Zapata AG.
Int J Dev Biol 53(7):971-82. 2009
13EFNB2, EPHB2
Ephrin-B2-induced cleavage of EphB2 receptor is mediated by matrix metalloproteinases to trigger cell repulsion.
Lin KT, Sloniowski S, Ethell DW, Ethell IM.
J Biol Chem 283(43):28969-79. Epub 2008 Aug 19. 2008
14EPHB2
Genetic and epigenetic analysis of the EPHB2 gene in gastric cancers.
Song JH, Kim CJ, Cho YG, Kwak HJ, Nam SW, Yoo NJ, Lee JY, Park WS.
APMIS 115(2):164-8. 2007
15RYK, EPHB2, EPHB3
A mutation in RYK is a genetic factor for nonsyndromic cleft lip and palate.
Watanabe A, Akita S, Tin NT, Natsume N, Nakano Y, Niikawa N, Uchiyama T, Yoshiura K.
Cleft Palate Craniofac J 43(3):310-6. 2006
16EPHB2, MAPK1, TSC1, TSC2
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.
Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP.
Cell 121(2):179-93. 2005
17EPHB2, CXCL16
CXCL16 is a novel angiogenic factor for human umbilical vein endothelial cells.
Zhuge X, Murayama T, Arai H, Yamauchi R, Tanaka M, Shimaoka T, Yonehara S, Kume N, Yokode M, Kita T.
Biochem Biophys Res Commun 331(4):1295-300. 2005
18EPHB1, EPHB2, EPHB3, GRIP1
GRIP1 controls dendrite morphogenesis by regulating EphB receptor trafficking.
Hoogenraad CC, Milstein AD, Ethell IM, Henkemeyer M, Sheng M.
Nat Neurosci 8(7):906-15. 2005
19EPHB2
EphB2 expression across 138 human tumor types in a tissue microarray: high levels of expression in gastrointestinal cancers.
Lugli A, Spichtin H, Maurer R, Mirlacher M, Kiefer J, Huusko P, Azorsa D, Terracciano L, Sauter G, Kallioniemi OP, Mousses S, Tornillo L.
Clin Cancer Res 11(18):6450-8. 2005
20EFNB2, EPHB2, EPHB4
Altered expression patterns of EphrinB2 and EphB2 in human umbilical vessels and congenital venous malformations.
Diehl S, Bruno R, Wilkinson GA, Loose DA, Wilting J, Schweigerer L, Klein R.
Pediatr Res 57(4):537-44. Epub 2005 Feb 17. 2005
21EPHB2
Nonsense-mediated decay microarray analysis identifies mutations of EPHB2 in human prostate cancer.
Huusko P, Ponciano-Jackson D, Wolf M, Kiefer JA, Azorsa DO, Tuzmen S, Weaver D, Robbins C, Moses T, Allinen M, Hautaniemi S, Chen Y, Elkahloun A, Basik M, Bova GS, Bubendorf L, Lugli A, Sauter G, Schleutker J, Ozcelik H, Elowe S, Pawson T, Trent JM, Carpten JD, Kallioniemi OP, Mousses S.
Nat Genet 36(9):979-83. Epub 2004 Aug 08. 2004
22AFDN, EPHB2, EPHB3, RYK
RYK, a catalytically inactive receptor tyrosine kinase, associates with EphB2 and EphB3 but does not interact with AF-6.
Trivier E, Ganesan TS.
J Biol Chem 277(25):23037-43. Epub 2002 Apr 15. 2002
23EPHB2
Genomic structure and loss of heterozygosity of EPHB2 in colorectal cancer.
Oba SM, Wang YJ, Song JP, Li ZY, Kobayashi K, Tsugane S, Hamada GS, Tanaka M, Sugimura H.
Cancer Lett 164(1):97-104. 2001
24EPHB2, RRAS
An Eph receptor regulates integrin activity through R-Ras.
Zou JX, Wang B, Kalo MS, Zisch AH, Pasquale EB, Ruoslahti E.
Proc Natl Acad Sci U S A 96(24):13813-8 1999
25EPHB2
Monomeric structure of the human EphB2 sterile alpha motif domain.
Thanos CD, Faham S, Goodwill KE, Cascio D, Phillips M, Bowie JU.
J Biol Chem 274(52):37301-6. 1999
26EPHB2
Molecular characterization and chromosomal localization of DRT (EPHT3) : a developmentally regulated human protein-tyrosine kinase gene of the EPH family.
Ikegaki N, et al.
Hum Mol Genet 4 : 2033-2045. 1995
27EPHB2
Identification of the human ERK gene as a putative receptor tyrosine kinase and its chromosomal localization to 1p36.1 : a comparative mapping of human, mouse, and rat chromosomes.
Saito T, et al.
Genomics 26 : 382-384. 1995
28EPHB2
Overexpression of ERK, an EPH family receptor protein tyrosine kinase, in various human tumors.
Kiyokawa E, et al.
Cancer Res 54 : 3645-3650. 1994
29EPHA8, EPHB2, MAPK1
eek and erk, new members of the eph subclass of receptor protein-tyrosine kinases.
Chan J, Watt VM.
Oncogene 6(6):1057-61. 1991
30EPHB1, EPHB2
A novel putative tyrosine kinase receptor encoded by the eph gene.
Hirai H, Maru Y, Hagiwara K, Nishida J, Takaku F.
Science 238 : 1717-1720. 1987