| 1 | EPCAM, HRAS, ZEB1
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| Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1
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| Omar FA, Brown TC, Gillanders WE, Fleming TP, Smith MA, Bremner RM, Sankpal NV.
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| PLoS One. May 16;18(5):e0285707. doi: 10.1371/journal.pone.0285707. 2023
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| 2 | CLDN7, EPCAM, TACSTD2
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| EPCAM and TROP2 share a role in claudin stabilization and development of intestinal and extraintestinal epithelia in mice.
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| Szabo R, Ward JM, Artunc F, Bugge TH.
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| Biol Open. ul 15;11(7):bio059403. doi: 10.1242/bio.059403. Epub 2022 Jul 11. 2022
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| 3 | EPCAM
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| Functional Implications of the Dynamic Regulation of EpCAM during Epithelial-to-Mesenchymal Transition.
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| Brown TC, Sankpal NV, Gillanders WE.
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| Biomolecules. Jun 29;11(7):956. doi: 10.3390/biom11070956. 2021
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| 4 | EPCAM
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| EpCAM is essential for maintenance of the small intestinal epithelium architecture via regulation of the expression and localization of proteins that compose adherens junctions
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| Chen G, Yang Y, Liu W, Huang L, Yang L, Lei Y, Wu H, Lei Z, Guo J.
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| Int J Mol Med. Feb;47(2):621-632. doi: 10.3892/ijmm.2020.4815. Epub 2020 Dec 10. 2021
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| 5 | EPCAM
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| EpCAM as Modulator of Tissue Plasticity
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| Fagotto F.
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| Cells. Sep 19;9(9):2128. doi: 10.3390/cells9092128. 2020
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| 6 | EPCAM
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| Revisiting the Roles of Pro-Metastatic EpCAM in Cancer
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| Mohtar MA, Syafruddin SE, Nasir SN, Low TY.
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| Biomolecules. Feb 7;10(2):255. doi: 10.3390/biom10020255. 2020
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| 7 | EPCAM
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| EpCAM cellular functions in adhesion and migration, and potential impact on invasion: A critical review.
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| Fagotto F, Aslemarz A.
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| Biochim Biophys Acta Rev Cancer. Dec;1874(2):188436. doi: 10.1016/j.bbcan.2020.188436. Epub 2020 Sep 22. 2020
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| 8 | EPCAM
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| The EpCAM overexpression is associated with clinicopathological significance and prognosis in hepatocellular carcinoma patients: A systematic review and meta-analysis.
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| Zhou L, Zhu Y.
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| Int J Surg. Aug;56:274-280. doi: 10.1016/j.ijsu.2018.06.025. Epub 2018 Jun 21 2018
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| 9 | EPCAM
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| EpCAM homo-oligomerization is not the basis for its role in cell-cell adhesion
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| Gaber A, Kim SJ, Kaake RM, Benčina M, Krogan N, Šali A, Pavšič M, Lenarčič B.
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| Sci Rep. Sep 5;8(1):13269. doi: 10.1038/s41598-018-31482-7. 2018
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| 10 | DIAR5, EPCAM
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| Novel Mutations in EPCAM Cause Congenital Tufting Enteropathy.
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| Tang W, Huang T, Xu Z, Huang Y.
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| J Clin Gastroenterol. Jan;52(1):e1-e6. doi: 10.1097/MCG.0000000000000739. 2018
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| 11 | EPCAM
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| The role of EpCAM in physiology and pathology of the epithelium.
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| Martowicz A, Seeber A, Untergasser G.
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| Histol Histopathol. Apr;31(4):349-55. doi: 10.14670/HH-11-678. Epub 2015 Oct 23. 2016
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| 12 | EPCAM
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| Expression of EpCAM(MF) and EpCAM(MT) variants in human carcinomas.
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| Fong D, Seeber A, Terracciano L, Kasal A, Mazzoleni G, Lehne F, Gastl G, Spizzo G.
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| J Clin Pathol 67(5):408-14. doi: 10.1136/jclinpath-2013-201932. Epub 2014 Jan 24.
2014
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| 13 | DIAR5, EPCAM
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| Tufting enteropathy revisited: the utility of MOC31 (EpCAM) immunohistochemistry in diagnosis.
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| Ranganathan S, Schmitt LA, Sindhi R.
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| Am J Surg Pathol 38(2):265-72. doi: 10.1097/PAS.0000000000000106.
2014
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| 14 | CSODS, DIAR5, EPCAM, SPINT2
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| Genetic characterization of congenital tufting enteropathy: epcam associated phenotype and involvement of SPINT2 in the syndromic form.
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| Salomon J, Goulet O, Canioni D, Brousse N, Lemale J, Tounian P, Coulomb A, Marinier E, Hugot JP, Ruemmele F, Dufier JL, Roche O, Bodemer C, Colomb V, Talbotec C, Lacaille F, Campeotto F, Cerf-Bensussan N, Janecke AR, Mueller T, Koletzko S, Bonnefont JP, Lyonnet S, Munnich A, Poirier F, Smahi A.
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| Hum Genet 133(3):299-310. doi: 10.1007/s00439-013-1380-6. Epub 2013 Oct 19.
2014
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| 15 | EPCAM, ERAP2
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| EpCAM associates with endoplasmic reticulum aminopeptidase 2 (ERAP2) in breast cancer cells.
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| Gadalla SE, Öjemalm K, Vasquez PL, Nilsson I, Ericsson C, Zhao J, Nistér M.
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| Biochem Biophys Res Commun 439(2):203-8. doi: 10.1016/j.bbrc.2013.08.059. Epub 2013 Aug 26.
2013
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| 16 | EPCAM
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| EpCAM overexpression prolongs proliferative capacity of primary human breast epithelial cells and supports hyperplastic growth.
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| Martowicz A, Rainer J, Lelong J, Spizzo G, Gastl G, Untergasser G.
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| Mol Cancer 12:56. doi: 10.1186/1476-4598-12-56.
2013
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| 17 | CLDN7, EPCAM
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| Epithelial cell adhesion molecule (EpCAM) regulates claudin dynamics and tight junctions.
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| Wu CJ, Mannan P, Lu M, Udey MC.
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| J Biol Chem 288(17):12253-68. doi: 10.1074/jbc.M113.457499. Epub 2013 Mar 13.
2013
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| 18 | DIAR5, EPCAM
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| Absence of cell-surface EpCAM in congenital tufting enteropathy.
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| Schnell U, Kuipers J, Mueller JL, Veenstra-Algra A, Sivagnanam M, Giepmans BN.
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| Hum Mol Genet 22(13):2566-71. doi: 10.1093/hmg/ddt105. Epub 2013 Mar 5.
2013
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| 19 | EPCAM
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| EpCAM regulates cell cycle progression via control of cyclin D1 expression.
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| Chaves-Pérez A, Mack B, Maetzel D, Kremling H, Eggert C, Harréus U, Gires O.
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| Oncogene 32(5):641-50. doi: 10.1038/onc.2012.75. Epub 2012 Mar 5.
2013
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| 20 | EPCAM, MMP7
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| MMP7 is a target of the tumour-associated antigen EpCAM.
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| Denzel S, Mack B, Eggert C, Massoner P, Stöcklein N, Kemming D, Harréus U, Gires O.
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| Int J Exp Pathol 93(5):341-53. doi: 10.1111/j.1365-2613.2012.00826.x.
2012
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| 21 | EPCAM
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| EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins.
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| Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, Yashiro K, Tsukita S, Hamada H.
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| Dev Biol 371(2):136-45. doi: 10.1016/j.ydbio.2012.07.005. Epub 2012 Jul 20.
2012
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| 22 | EPCAM
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| Cancer-associated epithelial cell adhesion molecule (EpCAM; CD326) enables epidermal Langerhans cell motility and migration in vivo.
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| Gaiser MR, Lämmermann T, Feng X, Igyarto BZ, Kaplan DH, Tessarollo L, Germain RN, Udey MC.
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| Proc Natl Acad Sci U S A 109(15):E889-97. doi: 10.1073/pnas.1117674109. Epub 2012 Mar 12.
2012
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| 23 | EPCAM, HNPCC1
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| Recurrence and variability of germline EPCAM deletions in Lynch syndrome.
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| Kuiper RP, Vissers LE, Venkatachalam R, Bodmer D, Hoenselaar E, Goossens M, Haufe A, Kamping E, Niessen RC, Hogervorst FB, Gille JJ, Redeker B, Tops CM, van Gijn ME, van den Ouweland AM, Rahner N, Steinke V, Kahl P, Holinski-Feder E, Morak M, Kloor M, Stemmler S, Betz B, Hutter P, Bunyan DJ, Syngal S, Culver JO, Graham T, Chan TL, Nagtegaal ID, van Krieken JH, Schackert HK, Hoogerbrugge N, van Kessel AG, Ligtenberg MJ.
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| Hum Mutat 32(4):407-14. doi: 10.1002/humu.21446. Epub 2011 Mar 1. 2011
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| 24 | EPCAM
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| Ep-CAM is a significant prognostic factor in pancreatic cancer patients by suppressing cell activity.
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| Akita H, Nagano H, Takeda Y, Eguchi H, Wada H, Kobayashi S, Marubashi S, Tanemura M, Takahashi H, Ohigashi H, Tomita Y, Ishikawa O, Mori M, Doki Y.
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| Oncogene 30(31):3468-76. doi: 10.1038/onc.2011.59. Epub 2011 Mar 14.
2011
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| 25 | CLDN7, EPCAM
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| Epithelial cell adhesion molecule (EpCAM) complex proteins promote transcription factor-mediated pluripotency reprogramming.
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| Huang HP, Chen PH, Yu CY, Chuang CY, Stone L, Hsiao WC, Li CL, Tsai SC, Chen KY, Chen HF, Ho HN, Kuo HC.
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| J Biol Chem 286(38):33520-32. Epub 2011 Jul 28.
2011
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| 26 | EPCAM
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| The tumor-associated EpCAM regulates morphogenetic movements through intracellular signaling.
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| Maghzal N, Vogt E, Reintsch W, Fraser JS, Fagotto F.
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| J Cell Biol 191(3):645-59. doi: 10.1083/jcb.201004074. Epub 2010 Oct 25.
2010
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| 27 | EPCAM, HNPCC1
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| Deletions removing the last exon of TACSTD1 constitute a distinct class of mutations predisposing to Lynch syndrome.
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| Kovacs ME, Papp J, Szentirmay Z, Otto S, Olah E.
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| Hum Mutat 30(2):197-203. 2009
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| 28 | EPCAM, HNPCC
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| Heritable somatic methylation and inactivation of MSH2 in families with Lynch syndrome due to deletion of the 3' exons of TACSTD1.
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| Ligtenberg MJ, Kuiper RP, Chan TL, Goossens M, Hebeda KM, Voorendt M, Lee TY, Bodmer D, Hoenselaar E, Hendriks-Cornelissen SJ, Tsui WY, Kong CK, Brunner HG, van Kessel AG, Yuen ST, van Krieken JH, Leung SY, Hoogerbrugge N.
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| Nat Genet 41(1):112-7. Epub 2008 Dec 21. 2009
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| 29 | DIAR5, EPCAM
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| Tufting enteropathy and chronic arthritis: a newly recognized association with a novel EpCAM gene mutation.
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| Al-Mayouf SM, Alswaied N, Alkuraya FS, Almehaidib A, Faqih M.
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| J Pediatr Gastroenterol Nutr 49(5):642-4. No abstract available. PMID: 19820410 2009
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| 30 | EPCAM
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| The emerging role of EpCAM in cancer and stem cell signaling.
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| Munz M, Baeuerle PA, Gires O.
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| Cancer Res 69(14):5627-9. Epub 2009 Jul 7. Review.PMID: 19584271 2009
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| 31 | EPCAM, MLH1
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| Germline hypermethylation of MLH1 and EPCAM deletions are a frequent cause of Lynch syndrome.
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| Niessen RC, Hofstra RM, Westers H, Ligtenberg MJ, Kooi K, Jager PO, de Groote ML, Dijkhuizen T, Olderode-Berends MJ, Hollema H, Kleibeuker JH, Sijmons RH.
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| Genes Chromosomes Cancer 48(8):737-44.PMID: 19455606 2009
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| 32 | EPCAM
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| EpCAM is overexpressed in gastric cancer and its downregulation suppresses proliferation of gastric cancer.
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| Wenqi D, Li W, Shanshan C, Bei C, Yafei Z, Feihu B, Jie L, Daiming F.
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| J Cancer Res Clin Oncol 135(9):1277-85. Epub 2009 Mar 18.PMID: 19294417 2009
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| 33 | DIAR5, EPCAM
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| Identification of EpCAM as the gene for congenital tufting enteropathy.
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| Sivagnanam M, Mueller JL, Lee H, Chen Z, Nelson SF, Turner D, Zlotkin SH, Pencharz PB, Ngan BY, Libiger O, Schork NJ, Lavine JE, Taylor S, Newbury RO, Kolodner RD, Hoffman HM.
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| Gastroenterology 135(2):429-37. Epub 2008 May 15.PMID: 18572020 [PubMed 2008
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| 34 | EPCAM
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| Prognostic significance of EpCAM expression in human esophageal cancer.
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| Kimura H, Kato H, Faried A, Sohda M, Nakajima M, Fukai Y, Miyazaki T, Masuda N, Fukuchi M, Kuwano H.
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| Int J Oncol 30(1):171-9. 2007
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| 35 | EPCAM, GDLD, TACSTD2
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| Phenotypic investigation of cell junction-related proteins in gelatinous drop-like corneal dystrophy.
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| Takaoka M, Nakamura T, Ban Y, Kinoshita S.
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| Invest Ophthalmol Vis Sci 48(3):1095-101. 2007
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| 36 | EPCAM
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| The cell-cell adhesion molecule EpCAM interacts directly with the tight junction protein claudin-7.
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| Ladwein M, Pape UF, Schmidt DS, Schnolzer M, Fiedler S, Langbein L, Franke WW, Moldenhauer G, Zoller M.
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| Exp Cell Res 309(2):345-57. 2005
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| 37 | EPCAM
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| EpCAM expression in retinoblastoma: a novel molecular target for therapy.
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| Krishnakumar S, Mohan A, Mallikarjuna K, Venkatesan N, Biswas J, Shanmugam MP, Ren-Heidenreich L.
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| Invest Ophthalmol Vis Sci 45(12):4247-50. 2004
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| 38 | EPCAM
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| The carcinoma-associated antigen EpCAM upregulates c-myc and induces cell proliferation.
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| Munz M, Kieu C, Mack B, Schmitt B, Zeidler R, Gires O.
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| Oncogene 23(34):5748-58. 2004
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| 39 | EPCAM
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| Cloning and characterisation of a 1.1 kb fragment of the carcinoma-associated epithelial cell adhesion molecule promoter.
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| Gires O, Eskofier S, Lang S, Zeidler R, Munz M.
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| Anticancer Res 23(4):3255-61. 2003
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| 40 | EPCAM, TACSTD2
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| Retroposition in a family of carcinoma-associated antigen genes.
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| Linnenbach AJ, et al.
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| Mol Cell Biol 13 : 1507-1515. 1993
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| 41 | EPCAM
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| Molecular cloning of cDNA for the carcinoma-associated antigen GA733-2.
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| Szala S, et al.
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| Proc Natl Acad Sci U S A 87 : 3542-3546. 1990
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| 42 | EPCAM, TACSTD2
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| Sequence investigation of the major gastrointestinal tumor-associated antigen gene family, GA733.
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| Linnenbach AJ, et al.
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| Proc Natl Acad Sci U S A 86(1):27-31. 1989
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| 43 | EPCAM
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| Characterization and chromosomal assignment of a human cell surface antigen defined by the monoclonal antiboby AUAI.
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| Spurr NK, et al.
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| Int J Cancer 38 : 631-636. 1986
|