1 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| Structural insights into the function of Elongator.
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| Dalwadi U, Yip CK.
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| Cell Mol Life Sci 75(9):1613-1622. doi: 10.1007/s00018-018-2747-6. Epub 2018 Jan 13. Review.
2018
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2 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| Molecular architecture of the yeast Elongator complex reveals an unexpected asymmetric subunit arrangement.
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| Setiaputra DT, Cheng DT, Lu S, Hansen JM, Dalwadi U, Lam CH, To JL, Dong MQ, Yip CK.
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| EMBO Rep 18(2):280-291. doi: 10.15252/embr.201642548. 2017
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3 | ELP4
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| Microdeletions of ELP4 Are Associated with Language Impairment, Autism Spectrum Disorder, and Mental Retardation.
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| Addis L, Ahn JW, Dobson R, Dixit A, Ogilvie CM, Pinto D, Vaags AK, Coon H, Chaste P, Wilson S, Parr JR, Andrieux J, Lenne B, Tumer Z, Leuzzi V, Aubell K, Koillinen H, Curran S, Marshall CR, Scherer SW, Strug LJ, Collier DA, Pal DK.
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| Hum Mutat 36(9):842-50. doi: 10.1002/humu.22816.
2015
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4 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| Dimerization of elongator protein 1 is essential for Elongator complex assembly.
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| Xu H, Lin Z, Li F, Diao W, Dong C, Zhou H, Xie X, Wang Z, Shen Y, Long J.
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| Proc Natl Acad Sci U S A 112(34):10697-702. doi: 10.1073/pnas.1502597112. Epub 2015 Aug 10.
2015
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5 | BDNF, ELP4
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| Association of brain-derived neurotrophic factor (BDNF) and elongator protein complex 4 (ELP4) polymorphisms with benign epilepsy with centrotemporal spikes in a Greek population.
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| Gkampeta A, Fidani L, Clarimón J, Kalinderi K, Katopodi T, Zafeiriou D, Pavlou E.
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| Epilepsy Res 108(10):1734-9. doi: 10.1016/j.eplepsyres.2014.09.005.
2014
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6 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| Structural insights into Elongator function.
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| Glatt S, Müller CW.
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| Curr Opin Struct Biol 23(2):235-42. doi: 10.1016/j.sbi.2013.02.009. Review. 2013
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7 | ELP3, ELP4, ELP5, ELP6
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| DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator.
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| Close P, Gillard M, Ladang A, Jiang Z, Papuga J, Hawkes N, Nguyen L, Chapelle JP, Bouillenne F, Svejstrup J, Fillet M, Chariot A.
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| J Biol Chem 287(39):32535-45.
2012
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8 | ELP4, ELP5, ELP6
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| Crystal structure of elongator subcomplex Elp4-6.
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| Lin Z, Zhao W, Diao W, Xie X, Wang Z, Zhang J, Shen Y, Long J.
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| J Biol Chem 287(25):21501-8. doi: 10.1074/jbc.M112.341560.
2012
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9 | ELP4, ELP5, ELP6
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| The Elongator subcomplex Elp456 is a hexameric RecA-like ATPase.
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| Glatt S, Létoquart J, Faux C, Taylor NM, Séraphin B, Müller CW.
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| Nat Struct Mol Biol 19(3):314-20. doi: 10.1038/nsmb.2234.
2012
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10 | ELP4
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| Centrotemporal sharp wave EEG trait in rolandic epilepsy maps to Elongator Protein Complex 4 (ELP4).
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| Strug LJ, Clarke T, Chiang T, Chien M, Baskurt Z, Li W, Dorfman R, Bali B, Wirrell E, Kugler SL, Mandelbaum DE, Wolf SM, McGoldrick P, Hardison H, Novotny EJ, Ju J, Greenberg DA, Russo JJ, Pal DK.
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| Eur J Hum Genet 17(9):1171-81. Epub 2009 Jan 28.PMID: 19172991 2009
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11 | ELP4
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| Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells.
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| Gu J, Sun D, Zheng Q, Wang X, Yang H, Miao J, Jiang J, Wei W.
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| Acta Biochim Biophys Sin (Shanghai) 41(10):831-8.PMID: 19779648 2009
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12 | ELP4
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| From rolandic epilepsy to continuous spike-and-waves during sleep and Landau-Kleffner syndromes: insights into possible genetic factors.
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| Rudolf G, Valenti MP, Hirsch E, Szepetowski P.
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| Epilepsia 50 Suppl 7:25-8.PMID: 19682046 2009
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13 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| Human Elongator complex is involved in cell cycle and suppresses cell growth in 293T human embryonic kidney cells.
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| Gu J, Sun D, Zheng Q, Wang X, Yang H, Miao J, Jiang J, Wei W.
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| Acta Biochim Biophys Sin (Shanghai) 41(10):831-8. 2009
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14 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| ELP3 localises to mitochondria and actin-rich domains at edges of HeLa cells.
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| Barton D, Braet F, Marc J, Overall R, Gardiner J.
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| Neurosci Lett 455(1):60-4. doi: 10.1016/j.neulet.2009.03.006. 2009
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15 | ELP1, ELP2, ELP3, ELP4, ELP5, ELP6
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| An early step in wobble uridine tRNA modification requires the Elongator complex.
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| Huang B, Johansson MJ, Byström AS.
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| RNA 11(4):424-36. 2005
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16 | MRPS22, FOXL2, COPB2, ELP4, BPES
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| FOXL2 inactivation by a translocation 171 kb away: analysis of 500 kb of chromosome 3 for candidate long-range regulatory sequences.
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| Crisponi L, Uda M, Deiana M, Loi A, Nagaraja R, Chiappe F, Schlessinger D, Cao A, Pilia G.
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| Genomics 83(5):757-64. 2004
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17 | ELP4, PAX6
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| PAX6 in sensory development.
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| Van Heyningen V, Williamson KA.
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| Hum Mol Genet 11(10):1161-7. 2002
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18 | ELP4
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| Characterization of a novel gene adjacent to PAX6, revealing synteny conservation with functional significance.
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| Kleinjan DA, Seawright A, Elgar G, van Heyningen V.
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| Mamm Genome 13(2):102-7. 2002
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19 | ELP4
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| Human Elongator facilitates RNA polymerase II transcription through chromatin.
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| Kim JH, Lane WS, Reinberg D.
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| Proc Natl Acad Sci U S A 99(3):1241-6. Epub 2002 Jan 29.PMID: 11818576 2002
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20 | ELP4, ELP5, ELP6
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| Elongator is a histone H3 and H4 acetyltransferase important for normal histone acetylation levels in vivo.
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| Winkler GS, Kristjuhan A, Erdjument-Bromage H, Tempst P, Svejstrup JQ.
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| Proc Natl Acad Sci U S A 99(6):3517-22.
2002
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