| 1 | ARHGEF16, ELMO1
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| Arhgef16, a novel Elmo1 binding partner, promotes clearance of apoptotic cells via RhoG-dependent Rac1 activation.
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| Lee J, Park B, Kim G, Kim K, Pak J, Kim K, Ye MB, Park SG, Park D.
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| Biochim Biophys Acta 1843(11):2438-2447. doi: 10.1016/j.bbamcr.2014.07.006. [Epub ahead of print]
2014
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| 2 | ELMO1, NCK1, RAC1
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| A novel interaction between SH2 domain of signaling adaptor protein Nck-1 and the upstream regulator of the Rho family GTPase Rac1-engulfment and cell motility 1 (ELMO1) promotes Rac1 activation and cell motility.
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| Zhang G, Chen X, Qiu F, Zhu F, Lei W, Nie J.
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| J Biol Chem Biol Chem. 2014 Jun 13. pii: jbc.M114.549550. [Epub ahead of print]
2014
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| 3 | DOCK2, ELMO1
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| Essential role of Elmo1 in Dock2-dependent lymphocyte migration.
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| Stevenson C, de la Rosa G, Anderson CS, Murphy PS, Capece T, Kim M, Elliott MR.
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| J Immunol 192(12):6062-70. doi: 10.4049/jimmunol.1303348. Epub 2014 May 12.
2014
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| 4 | DOCK1, ELMO1, ELMO2, ELMO3, MACF1
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| ELMO recruits actin cross-linking family 7 (ACF7) at the cell membrane for microtubule capture and stabilization of cellular protrusions.
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| Margaron Y, Fradet N, Côté JF.
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| J Biol Chem 288(2):1184-99. doi: 10.1074/jbc.M112.431825. Epub 2012 Nov 26. 2013
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| 5 | ELMO1, MED31
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| A link between the cytoplasmic engulfment protein Elmo1 and the Mediator complex subunit Med31.
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| Mauldin JP, Lu M, Das S, Park D, Ernst PB, Ravichandran KS.
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| Curr Biol 23(2):162-7. doi: 10.1016/j.cub.2012.11.049. Epub 2012 Dec 27.
2013
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| 6 | DOCK2, ELMO1
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| Structural basis for mutual relief of the Rac guanine nucleotide exchange factor DOCK2 and its partner ELMO1 from their autoinhibited forms.
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| Hanawa-Suetsugu K, Kukimoto-Niino M, Mishima-Tsumagari C, Akasaka R, Ohsawa N, Sekine S, Ito T, Tochio N, Koshiba S, Kigawa T, Terada T, Shirouzu M, Nishikimi A, Uruno T, Katakai T, Kinashi T, Kohda D, Fukui Y, Yokoyama S.
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| Proc Natl Acad Sci U S A 109(9):3305-10. doi: 10.1073/pnas.1113512109. Epub 2012 Feb 13.
2012
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| 7 | DOCK1, ELMO1, RHOG
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| The RhoG/ELMO1/Dock180 signaling module is required for spine morphogenesis in hippocampal neurons.
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| Kim JY, Oh MH, Bernard LP, Macara IG, Zhang H.
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| J Biol Chem 286(43):37615-24. doi: 10.1074/jbc.M111.268029. Epub 2011 Sep 7.
2011
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| 8 | ADGRB1, DOCK1, ELMO1
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| Unexpected requirement for ELMO1 in clearance of apoptotic germ cells in vivo.
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| Elliott MR, Zheng S, Park D, Woodson RI, Reardon MA, Juncadella IJ, Kinchen JM, Zhang J, Lysiak JJ, Ravichandran KS.
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| Nature 467(7313):333-7.PMID: 20844538 2010
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| 9 | ELMO1
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| ELMO1 variants and susceptibility to diabetic nephropathy in American Indians.
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| Hanson RL, Millis MP, Young NJ, Kobes S, Nelson RG, Knowler WC, DiStefano JK.
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| Mol Genet Metab 101(4):383-90. Epub 2010 Aug 19.
2010
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| 10 | ELMO1
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| Molecular cloning of t(2;7)(p24.3;p14.2), a novel chromosomal translocation in myelodysplastic syndrome-derived acute myeloid leukemia.
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| Fujita K, Sanada M, Harada H, Mori H, Niikura H, Omine M, Inazawa J, Imoto I.
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| J Hum Genet 54(6):355-9. Epub 2009 May 1.
2009
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| 11 | DOCK1, ELMO1
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| An alpha-helical extension of the ELMO1 pleckstrin homology domain mediates direct interaction to DOCK180 and is critical in Rac signaling.
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| Komander D, Patel M, Laurin M, Fradet N, Pelletier A, Barford D, Côté JF.
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| Mol Biol Cell 19(11):4837-51. Epub 2008 Sep 3.
2008
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| 12 | ELMO1
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| Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.
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| Handa Y, Suzuki M, Ohya K, Iwai H, Ishijima N, Koleske AJ, Fukui Y, Sasakawa C.
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| Nat Cell Biol 9(1):121-8. Epub 2006 Dec 17. 2007
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| 13 | ADGRB1, DOCK1, ELMO1
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| BAI1 is an engulfment receptor for apoptotic cells upstream of the ELMO/Dock180/Rac module.
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| Park D, Tosello-Trampont AC, Elliott MR, Lu M, Haney LB, Ma Z, Klibanov AL, Mandell JW, Ravichandran KS.
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| Nature 450(7168):430-4. 2007
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| 14 | ELMO1, HCK
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| Identification of tyrosine residues on ELMO1 that are phosphorylated by the Src-family kinase Hck.
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| Yokoyama N, deBakker CD, Zappacosta F, Huddleston MJ, Annan RS, Ravichandran KS, Miller WT.
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| Biochemistry 44(24):8841-9. 2005
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| 15 | ELMO1
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| Genetic variations in the gene encoding ELMO1 are associated with susceptibility to diabetic nephropathy.
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| Shimazaki A, Kawamura Y, Kanazawa A, Sekine A, Saito S, Tsunoda T, Koya D, Babazono T, Tanaka Y, Matsuda M, Kawai K, Iiizumi T, Imanishi M, Shinosaki T, Yanagimoto T, Ikeda M, Omachi S, Kashiwagi A, Kaku K, Iwamoto Y, Kawamori R, Kikkawa R, Nakajima M, Nakamura Y, Maeda S.
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| Diabetes 54(4):1171-8. 2005
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| 16 | DOCK2, ELMO1
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| DOCK2 regulates Rac activation and cytoskeletal reorganization through interaction with ELMO1.
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| Sanui T, Inayoshi A, Noda M, Iwata E, Stein JV, Sasazuki T, Fukui Y.
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| Blood 102(8):2948-50. Epub 2003 Jun 26. 2003
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| 17 | DOCK1,ELMO1,ELMO2,RHOG
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| RhoG activates Rac1 by direct interaction with the Dock180-binding protein Elmo.
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| Katoh H, Negishi M.
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| Nature 424(6947):461-4. 2003
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| 18 | ELMO1, ELMO2, ELMO3, JMJD6
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| Cell corpse engulfment mediated by C. elegans phosphatidylserine receptor through CED-5 and CED-12.
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| Wang X, Wu YC, Fadok VA, Lee MC, Gengyo-Ando K, Cheng LC, Ledwich D, Hsu PK, Chen JY, Chou BK, Henson P, Mitani S, Xue D.
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| Science 302(5650):1563-6.
2003
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| 19 | CRK, DOCK1, ELMO1, ELMO2, ELMO3, RAC1
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| CED-12/ELMO, a novel member of the CrkII/Dock180/Rac pathway, is required for phagocytosis and cell migration.
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| Gumienny TL, Brugnera E, Tosello-Trampont AC, Kinchen JM, Haney LB, Nishiwaki K, Walk SF, Nemergut ME, Macara IG, Francis R, Schedl T, Qin Y, Van Aelst L, Hengartner MO, Ravichandran KS.
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| Cell 107(1):27-41. 2001
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