Citations for
1E2F1, ELL
ELL inhibits E2F1 transcriptional activity by enhancing E2F1 deacetylation via recruitment of histone deacetylase 1.
Zhang W, Ji W, Liu X, Ouyang G, Xiao W.
Mol Cell Biol 34(4):765-75. doi: 10.1128/MCB.00878-13. Epub 2013 Dec 16. 2014
2CDK7, ELL, GTF2H2
ELL, a novel TFIIH partner, is involved in transcription restart after DNA repair.
Mourgues S, Gautier V, Lagarou A, Bordier C, Mourcet A, Slingerland J, Kaddoum L, Coin F, Vermeulen W, Gonzales de Peredo A, Monsarrat B, Mari PO, Giglia-Mari G.
Proc Natl Acad Sci U S A 110(44):17927-32. doi: 10.1073/pnas.1305009110. Epub 2013 Oct 14. 2013
3ELL, ELL2, ELL3
The RNA Pol II elongation factor Ell3 marks enhancers in ES cells and primes future gene activation.
Lin C, Garruss AS, Luo Z, Guo F, Shilatifard A.
Cell 152(1-2):144-56. doi: 10.1016/j.cell.2012.12.015. Epub 2012 Dec 27. 2013
4CCNT1, ELL, KMT2A
The super elongation complex (SEC) family in transcriptional control.
Luo Z, Lin C, Shilatifard A.
Nat Rev Mol Cell Biol 13(9):543-7. doi: 10.1038/nrm3417. Epub 2012 Aug 16. Review. 2012
5ELL
ELL facilitates RNA polymerase II pause site entry and release.
Byun JS, Fufa TD, Wakano C, Fernandez A, Haggerty CM, Sung MH, Gardner K.
Nat Commun 3:633. doi: 10.1038/ncomms1652. 2012
6CCNT1, ELL, MED26
Human mediator subunit MED26 functions as a docking site for transcription elongation factors.
Takahashi H, Parmely TJ, Sato S, Tomomori-Sato C, Banks CA, Kong SE, Szutorisz H, Swanson SK, Martin-Brown S, Washburn MP, Florens L, Seidel CW, Lin C, Smith ER, Shilatifard A, Conaway RC, Conaway JW.
Cell 146(1):92-104. doi: 10.1016/j.cell.2011.06.005. 2011
7ELL, HIF1A
ELL is an HIF-1alpha partner that regulates and responds to hypoxia response in PC3 cells.
Liu L, Ai J, Xiao W, Liu J, Wang Y, Xin D, He Z, Guo Y, Wang Z.
Prostate 70(7):797-805. doi: 10.1002/pros.21113. 2010
8ELL, THBS1
Elongation factor ELL (Eleven-Nineteen Lysine-rich Leukemia) acts as a transcription factor for direct thrombospondin-1 regulation.
Zhou J, Feng X, Ban B, Liu J, Wang Z, Xiao W.
J Biol Chem 284(28):19142-52. Epub 2009 May 15. 2009
9ELL, MCM2, SNF8
The interaction between EAP30 and ELL is modulated by MCM2.
Mathews A, Holland L, Yankulov K.
FEBS Lett 583(21):3431-6. doi: 10.1016/j.febslet.2009.10.009. Epub 2009 Oct 9. 2009
10EAF1, EAF2, ELL, TFPT
FB1, an E2A fusion partner in childhood leukemia, interacts with U19/EAF2 and inhibits its transcriptional activity.
Jiang F, Ai J, Xiao W, Wang Z.
Cancer Lett 253(2):265-72. Epub 2007 Mar 28. 2007
11EAF2, ELL
Apoptosis induction and growth suppression by U19/Eaf2 is mediated through its ELL-binding domain.
Hahn J, Xiao W, Jiang F, Simone F, Thirman MJ, Wang Z.
Prostate 67(2):146-53.PMID: 17044034 2007
12EAF1, EAF2, ELL
ELL-associated factors 1 and 2 are positive regulators of RNA polymerase II elongation factor ELL.
Kong SE, Banks CA, Shilatifard A, Conaway JW, Conaway RC.
Proc Natl Acad Sci U S A 102(29):10094-8. Epub 2005 Jul 8. 2005
13EAF1,ELL
ELL and EAF1 are Cajal body components that are disrupted in MLL-ELL leukemia.
Polak PE, Simone F, Kaberlein JJ, Luo RT, Thirman MJ.
Mol Biol Cell 14(4):1517-28. Erratum in: Mol Biol Cell.2003 May;14(5):following table of contents. 2003
14ELL, EAF1, EAF2
EAF1, a novel ELL-associated factor that is delocalized by expression of the MLL-ELL fusion protein.
Simone F, Polak PE, Kaberlein JJ, Luo RT, Levitan DA, Thirman MJ.
Blood 98(1):201-9. 2001
15ELL, ELL2, ELL3
Functional analysis of the leukemia protein ELL: evidence for a role in the regulation of cell growth and survival.
Johnstone RW, Gerber M, Landewe T, Tollefson A, Wold WS, Shilatifard A.
Mol Cell Biol 21(5):1672-81. 2001
16SNF8, ELL
Cloning and characterization of the EAP30 subunit of the ELL complex that confers derepression of transcription by RNA polymerase II.
Schmidt AE, Miller T, Schmidt SL, Shiekhattar R, Shilatifard A.
J Biol Chem 274(31):21981-5. 1999
17ELL
Structure and function of RNA polymerase II elongation factor ELL. Identification of two overlapping ELL functional domains that govern its interaction with polymerase and the ternary elongation complex.
Shilatifard A, Haque D, Conaway RC, Conaway JW.
J Biol Chem 272(35):22355-63. 1997
18ELL, KMT2A
Cloning of ELL, a gene that fuses to MLL in a t(11;19)(q23;p13.1) in acute myeloid leukemia.
Thirman MJ, et al.
Proc Natl Acad Sci U S A 91 : 12110-12114. 1994