1 | EIF2S2
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| eIF2β, a subunit of translation-initiation factor EIF2, is a potential therapeutic target for non-small cell lung cancer.
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| Tanaka I, Sato M, Kato T, Goto D, Kakumu T, Miyazawa A, Yogo N, Hase T, Morise M, Sekido Y, Girard L, Minna JD, Byers LA, Heymach JV, Coombes KR, Kondo M, Hasegawa Y.
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| Cancer Sci 109(6):1843-1852. doi: 10.1111/cas.13602. Epub 2018 May 25.
2018
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2 | EIF2S2, EIF5
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| Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
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| Llácer JL, Hussain T, Saini AK, Nanda JS, Kaur S, Gordiyenko Y, Kumar R, Hinnebusch AG, Lorsch JR, Ramakrishnan V.
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| Elife 7. pii: e39273. doi: 10.7554/eLife.39273.
2018
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3 | CXCL12, CXCR4, EIF2S2
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| Association of eukaryotic translation initiation factor eIF2B with fully solubilized CXCR4.
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| Palmesino E, Apuzzo T, Thelen S, Mueller B, Langen H, Thelen M.
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| J Leukoc Biol 99(6):971-8. doi: 10.1189/jlb.2MA0915-415R. Epub 2015 Nov 25.
2016
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4 | EIF2S2, EIF2S3, EIF5
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| eIF2β is critical for eIF5-mediated GDP-dissociation inhibitor activity and translational control.
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| Jennings MD, Kershaw CJ, White C, Hoyle D, Richardson JP, Costello JL, Donaldson IJ, Zhou Y, Pavitt GD.
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| Nucleic Acids Res 44(20):9698-9709. Epub 2016 Jul 25.
2016
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5 | CDC123, EIF2S1, EIF2S2, EIF2S3
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| Translation initiation requires cell division cycle 123 (Cdc123) to facilitate biogenesis of the eukaryotic initiation factor 2 (eIF2)
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| Perzlmaier AF, Richter F, Seufert W.
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| J Biol Chem. Jul 26;288(30):21537-46. doi: 10.1074/jbc.M113.472290. Epub 2013 Jun 17. 2013
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6 | EIF1, EIF2S2, EIF5
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| The C-terminal domain of eukaryotic initiation factor 5 promotes start codon recognition by its dynamic interplay with eIF1 and eIF2β.
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| Luna RE, Arthanari H, Hiraishi H, Nanda J, Martin-Marcos P, Markus MA, Akabayov B, Milbradt AG, Luna LE, Seo HC, Hyberts SG, Fahmy A, Reibarkh M, Miles D, Hagner PR, O'Day EM, Yi T, Marintchev A, Hinnebusch AG, Lorsch JR, Asano K, Wagner G.
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| Cell Rep 1(6):689-702. doi: 10.1016/j.celrep.2012.04.007. Epub 2012 May 24.
2012
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7 | EIF2S2
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| Deletion of eIF2beta suppresses testicular cancer incidence and causes recessive lethality in agouti-yellow mice.
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| Heaney JD, Michelson MV, Youngren KK, Lam MY, Nadeau JH.
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| Hum Mol Genet 18(8):1395-404. doi: 10.1093/hmg/ddp045. Epub 2009 Jan 23.
2009
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8 | EIF2S1, EIF2S2
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| Intersubunit and interprotein interactions of alpha- and beta-subunits of human eIF2: Effect of phosphorylation.
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| Rajesh K, Iyer A, Suragani RN, Ramaiah KV.
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| Biochem Biophys Res Commun 374(2):336-40. doi: 10.1016/j.bbrc.2008.07.022. Epub 2008 Jul 17.
2008
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9 | EIF1, EIF2S2, EIF3C, EIF5
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| The crystal structure of the carboxy-terminal domain of human translation initiation factor eIF5.
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| Bieniossek C, Schütz P, Bumann M, Limacher A, Uson I, Baumann U.
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| J Mol Biol 360(2):457-65. Epub 2006 May 24.
2006
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10 | EIF2S1, EIF2S2, EIF2S3
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| Interaction of recombinant human eIF2 subunits with eIF2B and eIF2alpha kinases.
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| Suragani RN, Kamindla R, Ehtesham NZ, Ramaiah KV.
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| Biochem Biophys Res Commun 338(4):1766-72. Epub 2005 Nov 2. 2005
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11 | EIF2S2
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| Genomic cloning and characterization of the human eukaryotic initiation factor-2beta promoter.
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| Chiorini JA, Miyamoto S, Harkin SJ, Safer B.
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| J Biol Chem 274(7):4195-201. 1999
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12 | EIF2S2, EIF2S3P
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| Characterization of genes encoding translation initiation factor eIF-2gamma in mouse and human: sex chromosome localization, escape from X-inactivation and evolution.
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| Ehrmann IE, et al.
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| Hum Mol Genet 7(11):1725-37 1998
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13 | EIF2S2, EIF2S3
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| Translation initiation factor eIF-2. Cloning and expression of the human cDNA encoding the gamma-subunit.
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| Gaspar NJ, Kinzy TG, Scherer BJ, Humbelin M, Hershey JW, Merrick WC.
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| J Biol Chem 269 : 3415-3422. 1994
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14 | EIF2S2
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| Structure of the beta subunit of translational initiation factor eIF-2.
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| Pathak VK, Nielsen PJ, Trachsel H, Hershey JW.
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| Cell 54(5):633-9. 1988
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