| 1 | EGR2, PMP22, SOX10, TEAD1
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| Tead1 regulates the expression of Peripheral Myelin Protein 22 during Schwann cell development.
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| Lopez-Anido C, Poitelon Y, Gopinath C, Moran JJ, Ma KH, Law WD, Antonellis A, Feltri ML, Svaren J.
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| Hum Mol Genet 25(14):3055-3069. Epub 2016 Jun 10.
2016
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| 2 | EGR1, EGR2
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| Elevated and sustained expression of the transcription factors Egr1 and Egr2 controls NKT lineage differentiation in response to TCR signaling.
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| Seiler MP, Mathew R, Liszewski MK, Spooner C, Barr K, Meng F, Singh H, Bendelac A.
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| Nat Immunol at Immunol. 2012 Feb 5. doi: 10.1038/ni.2230. [Epub ahead of print]
2012
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| 3 | EGR1, EGR2
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| Early growth response genes signaling supports strong paracrine capability of mesenchymal stem cells.
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| Tamama K, Barbeau DJ.
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| Stem Cells Int 2012:428403. doi: 10.1155/2012/428403. Epub 2012 Dec 6.
2012
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| 4 | EGR2
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| Egr2-neurons control the adult respiratory response to hypercapnia.
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| Ray RS, Corcoran AE, Brust RD, Soriano LP, Nattie EE, Dymecki SM.
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| Brain Res rain Res. 2012 Dec 19. doi:pii: S0006-8993(12)01907-5. 10.1016/j.brainres.2012.12.017. [Epub ahead of print]
2012
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| 5 | EGR2
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| Transcriptional regulator early growth response gene 2 (Egr2) is required for T cell anergy in vitro and in vivo.
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| Zheng Y, Zha Y, Driessens G, Locke F, Gajewski TF.
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| J Exp Med 209(12):2157-63. doi: 10.1084/jem.20120342. Epub 2012 Nov 5.
2012
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| 6 | EGR2, EGR3
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| The transcription factors Egr2 and Egr3 are essential for the control of inflammation and antigen-induced proliferation of B and T cells.
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| Li S, Miao T, Sebastian M, Bhullar P, Ghaffari E, Liu M, Symonds AL, Wang P.
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| Immunity 37(4):685-96. doi: 10.1016/j.immuni.2012.08.001. Epub 2012 Sep 27.
2012
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| 7 | EGR2, TNFSF11
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| Early growth response 2 negatively modulates osteoclast differentiation through upregulation of Id helix-loop-helix proteins.
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| Kim HJ, Hong JM, Yoon KA, Kim N, Cho DW, Choi JY, Lee IK, Kim SY.
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| Bone 51(4):643-50. doi: 10.1016/j.bone.2012.07.015. Epub 2012 Jul 26.
2012
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| 8 | CMT4E, EGR2
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| Homozygous deletion of an EGR2 enhancer in congenital amyelinating neuropathy.
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| Funalot B, Topilko P, Arroyo MA, Sefiani A, Hedley-Whyte ET, Yoldi ME, Richard L, Touraille E, Laurichesse M, Khalifa E, Chauzeix J, Ouedraogo A, Cros D, Magdelaine C, Sturtz FG, Urtizberea JA, Charnay P, Bragado FG, Vallat JM.
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| Ann Neurol 71(5):719-23. doi: 10.1002/ana.23527.
2012
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| 9 | EGR2, TARDBP
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| Common variants near TARDBP and EGR2 are associated with susceptibility to Ewing sarcoma.
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| Postel-Vinay S, Véron AS, Tirode F, Pierron G, Reynaud S, Kovar H, Oberlin O, Lapouble E, Ballet S, Lucchesi C, Kontny U, González-Neira A, Picci P, Alonso J, Patino-Garcia A, de Paillerets BB, Laud K, Dina C, Froguel P, Clavel-Chapelon F, Doz F, Michon J, Chanock SJ, Thomas G, Cox DG, Delattre O.
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| Nat Genet 44(3):323-7. doi: 10.1038/ng.1085.
2012
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| 10 | EGR2, UBE2I
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| The transcription factor Krox20 is an E3 ligase that sumoylates its Nab coregulators.
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| García-Gutiérrez P, Juárez-Vicente F, Gallardo-Chamizo F, Charnay P, García-Domínguez M.
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| EMBO Rep 12(10):1018-23. doi: 10.1038/embor.2011.152.
2011
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| 11 | EGR2
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| Early growth response gene-2 (Egr-2) regulates the development of B and T cells.
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| Li S, Symonds AL, Zhu B, Liu M, Raymond MV, Miao T, Wang P.
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| PLoS One 6(4):e18498. doi: 10.1371/journal.pone.0018498.
2011
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| 12 | EGR1, EGR2
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| EGR1 and EGR2 involvement in vertebrate tendon differentiation.
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| Lejard V, Blais F, Guerquin MJ, Bonnet A, Bonnin MA, Havis E, Malbouyres M, Bidaud CB, Maro G, Gilardi-Hebenstreit P, Rossert J, Ruggiero F, Duprez D.
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| J Biol Chem 286(7):5855-67. doi: 10.1074/jbc.M110.153106. Epub 2010 Dec 20.
2011
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| 13 | EGR2, SOX10
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| Locus-wide identification of Egr2/Krox20 regulatory targets in myelin genes.
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| Jang SW, Srinivasan R, Jones EA, Sun G, Keles S, Krueger C, Chang LW, Nagarajan R, Svaren J.
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| J Neurochem 115(6):1409-20. doi: 10.1111/j.1471-4159.2010.07045.x. Epub 2010 Nov 4.
2010
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| 14 | EGR2, YY1
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| Yy1 as a molecular link between neuregulin and transcriptional modulation of peripheral myelination.
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| He Y, Kim JY, Dupree J, Tewari A, Melendez-Vasquez C, Svaren J, Casaccia P.
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| Nat Neurosci 13(12):1472-80. doi: 10.1038/nn.2686. Epub 2010 Nov 7.
2010
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| 15 | EGR2
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| Identification and characterization of early growth response 2, a zinc-finger transcription factor, as a p53-regulated proapoptotic gene.
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| Yokota I, Sasaki Y, Kashima L, Idogawa M, Tokino T.
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| Int J Oncol 37(6):1407-16.
2010
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| 16 | EGR1, EGR2, EGR3
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| EGR1, EGR2, and EGR3 activate the expression of their coregulator NAB2 establishing a negative feedback loop in cells of neuroectodermal and epithelial origin.
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| Kumbrink J, Kirsch KH, Johnson JP.
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| J Cell Biochem 111(1):207-17. doi: 10.1002/jcb.22690.
2010
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| 17 | EGR2, MECP2, RTT
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| Reciprocal co-regulation of EGR2 and MECP2 is disrupted in Rett syndrome and autism.
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| Swanberg SE, Nagarajan RP, Peddada S, Yasui DH, LaSalle JM.
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| Hum Mol Genet 18(3):525-34. Epub 2008 Nov 10.
2009
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| 18 | EGR1, EGR2
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| The transcription factors Egr1 and Egr2 have opposing influences on adipocyte differentiation.
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| Boyle KB, Hadaschik D, Virtue S, Cawthorn WP, Ridley SH, O'Rahilly S, Siddle K.
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| Cell Death Differ 16(5):782-9. Epub 2009 Feb 20.
2009
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| 19 | ADAM19, EGR2
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| Roles of meltrin-beta/ADAM19 in progression of Schwann cell differentiation and myelination during sciatic nerve regeneration.
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| Wakatsuki S, Yumoto N, Komatsu K, Araki T, Sehara-Fujisawa A.
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| J Biol Chem 284(5):2957-66. Epub 2008 Dec 2.
2009
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| 20 | EGR1, EGR2, EGR3
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| Epidermal-growth-factor-induced proliferation of astrocytes requires Egr transcription factors.
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| Mayer SI, Rössler OG, Endo T, Charnay P, Thiel G.
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| J Cell Sci 122(Pt 18):3340-50. doi: 10.1242/jcs.048272. Epub 2009 Aug 25.
2009
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| 21 | CMT1D, EGR2
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| Functional, histopathologic and natural history study of neuropathy associated with EGR2 mutations.
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| Szigeti K, Wiszniewski W, Saifi GM, Sherman DL, Sule N, Adesina AM, Mancias P, Papasozomenos SCh, Miller G, Keppen L, Daentl D, Brophy PJ, Lupski JR.
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| Neurogenetics 8(4):257-62. Epub 2007 Aug 24.
2007
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| 22 | CMT1D, EGR2
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| Mutation frequency for Charcot-Marie-Tooth disease type 1 in the Chinese population is similar to that in the global ethnic patients.
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| Song S, Zhang Y, Chen B, Zhang Y, Wang M, Wang Y, Yan M, Zou J, Huang Y, Zhong N.
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| Genet Med 8(8):532-5.
2006
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| 23 | EGR2
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| Krox20 stimulates adipogenesis via C/EBP beta-dependent and -independent mechanisms
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| Chen Z, et al
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| Cell metabolism 1(2):93-105. 2005
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| 24 | CMT1D, EGR2
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| Novel EGR2 mutation R359Q is associated with CMT type 1 and progressive scoliosis.
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| Mikesová E, Hühne K, Rautenstrauss B, Mazanec R, Baránková L, Vyhnálek M, Horácek O, Seeman P.
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| Neuromuscul Disord 15(11):764-7. Epub 2005 Sep 29.
2005
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| 25 | EGR2
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| Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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| Unoki M, Nakamura Y.
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| FEBS Lett 554(1-2):67-72. 2003
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| 26 | ABTB1, DUSP1, EGR2, HCLS1, NFIL3, PINK1
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| Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.
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| Unoki M, Nakamura Y.
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| Oncogene 20(33):4457-65. 2001
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| 27 | EGR2, HMSNR
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| A novel locus for autosomal recessive peripheral neuropathy in the EGR2 region on 10q23.
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| Rogers T, Chandler D, Angelicheva D, Thomas PK, Youl B, Tournev I, Gergelcheva V, Kalaydjieva L.
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| Am J Hum Genet 67(3):664-71. 2000
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| 28 | EGR2, CMT1D
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| Functional consequences of mutations in the early growth response 2 gene (EGR2) correlate with severity of human myelinopathies.
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| Warner LE, et al.
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| Hum Mol Genet 8(7):1245-1251. 1999
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| 29 | EGR2, CMT1D
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| Novel missense mutation in the early growth response 2 gene associated with Dejerine-Sottas syndrome phenotype.
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| Timmerman V, et al.
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| Neurology 52(9):1827-32. 1999
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| 30 | CMT1D, EGR2, CMT4E
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| Mutations in the early growth response 2 (EGR2) gene are associated with hereditary myelinopathies.
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| Warner LE, Mancias P, Butler IJ, McDonald CM, Keppen L, Koob KG, Lupski JR.
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| Nat Genet 18(4):382-4. 1998
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| 31 | EGR2
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| The segment-specific gene Krox-20 encodes a transcription factor with binding sites in the promoter region of the Hox-1.4 gene.
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| Chavrier P, et al.
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| EMBO J 9 : 1209-1218. 1990
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| 32 | EGR2
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| Structure, chromosome localisation and expression of the mouse zinc finger gene Krox-20 : multiple gene products and coregulation with the protooncogene c-fos.
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| Chavrier P, Janssen-Timmen U, Mattei MG, Zerial M, Bravo R, Charnay P.
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| Mol Cell Biol 9 : 787-797. 1989
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| 33 | EGR2
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| A HindIII polymorphism identified by the human early growth response gene 2 (EGR2) on chromosome 10.
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| Wu J, Joseph L, Sukhatme VP, Kidd KK.
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| Nucleic Acids Res 16 : 11855. 1988
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| 34 | EGR2
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| Molecular cloning, sequencing, and mapping of EGR2, a human early growth response gene encoding a protein with zinc-binding finger structure.
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| Joseph LJ, et al.
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| Proc Natl Acad Sci U S A 85 : 7164-7168. 1988
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