| 1 | EGFR, ZDHHC20
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| Regulation of EGFR signalling by palmitoylation and its role in tumorigenesis
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| Kadry YA, Lee JY, Witze ES.
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| Open Biol. Oct;11(10):210033. doi: 10.1098/rsob.210033. Epub 2021 Oct 6. 2021
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| 2 | EGFR, MITF, NFE2L2, TGFA
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| NRF2 Enables EGFR Signaling in Melanoma Cells.
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| Kreß JKC, Jessen C, Marquardt A, Hufnagel A, Meierjohann S.
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| Int J Mol Sci. Apr 7;22(8):3803. doi: 10.3390/ijms22083803. 2021
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| 3 | EGFR, RNF144A
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| RNF144A sustains EGFR signaling to promote EGF-dependent cell proliferation
|
| Ho SR, Lin WC.
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| J Biol Chem. Oct 19;293(42):16307-16323. doi: 10.1074/jbc.RA118.002887. Epub 2018 Aug 31. 2018
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| 4 | CHRM3, EGFR, MAPK14, TNF
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| Activation of muscarinic receptors prevents TNF-α-mediated intestinal epithelial barrier disruption through p38 MAPK.
|
| Uwada J, Yazawa T, Islam MT, Khan MRI, Krug SM, Fromm M, Karaki SI, Suzuki Y, Kuwahara A, Yoshiki H, Sada K, Muramatsu I, Taniguchi T.
|
| Cell Signal 35:188-196. doi: 10.1016/j.cellsig.2017.04.007. Epub 2017 Apr 12.
2017
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| 5 | EGFR, TFRC
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| EGFR regulates iron homeostasis to promote cancer growth through redistribution of transferrin receptor 1.
|
| Wang B, Zhang J, Song F, Tian M, Shi B, Jiang H, Xu W, Wang H, Zhou M, Pan X, Gu J, Yang S, Jiang L, Li Z.
|
| Cancer Lett 381(2):331-40. doi: 10.1016/j.canlet.2016.08.006. Epub 2016 Aug 11.
2016
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| 6 | DPYD, EGFR
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| Epidermal growth factor signals regulate dihydropyrimidine dehydrogenase expression in EGFR-mutated non-small-cell lung cancer.
|
| Tominaga T, Tsuchiya T, Mochinaga K, Arai J, Yamasaki N, Matsumoto K, Miyazaki T, Nagasaki T, Nanashima A, Tsukamoto K, Nagayasu T.
|
| BMC Cancer 16:354. doi: 10.1186/s12885-016-2392-0.
2016
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| 7 | EGFR, TMPRSS11E
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| DESC1, a novel tumor suppressor, sensitizes cells to apoptosis by downregulating the EGFR/AKT pathway in esophageal squamous cell carcinoma.
|
| Ng HY, Ko JM, Yu VZ, Ip JC, Dai W, Cal S, Lung ML.
|
| Int J Cancer 138(12):2940-51. doi: 10.1002/ijc.30034. Epub 2016 Feb 26.
2016
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| 8 | AVPR2, EGFR, ERBB2
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| Therapeutic targets for polycystic kidney disease
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| Wilson PD.
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| Expert Opin Ther Targets. 2016;20(1):35-45. doi: 10.1517/14728222.2015.1083979. Epub 2015 Aug 31. 2016
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| 9 | ARHGEF6, CBL, EGFR
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| αPIX Is a Trafficking Regulator that Balances Recycling and Degradation of the Epidermal Growth Factor Receptor.
|
| Kortüm F, Harms FL, Hennighausen N, Rosenberger G.
|
| PLoS One 10(7):e0132737. doi: 10.1371/journal.pone.0132737.
2015
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| 10 | EGFR, SULF1, SULF2
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| Sulf1 and Sulf2 expression in the nervous system and its role in limiting neurite outgrowth in vitro.
|
| Joy MT, Vrbova G, Dhoot GK, Anderson PN.
|
| Exp Neurol 263:150-60. doi: 10.1016/j.expneurol.2014.10.011. Epub 2014 Oct 23.
2015
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| 11 | EGFR, RASGRP1, SOS1
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| RasGRP1 opposes proliferative EGFR-SOS1-Ras signals and restricts intestinal epithelial cell growth.
|
| Depeille P, Henricks LM, van de Ven RA, Lemmens E, Wang CY, Matli M, Werb Z, Haigis KM, Donner D, Warren R, Roose JP.
|
| Nat Cell Biol 17(6):804-15. doi: 10.1038/ncb3175. Epub 2015 May 25.
2015
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| 12 | DSC3, EGFR
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| Desmocollin 3 mediates follicle stimulating hormone-induced ovarian epithelial cancer cell proliferation by activating the EGFR/Akt signaling pathway.
|
| Yang X, Wang J, Li WP, Jin ZJ, Liu XJ.
|
| Int J Clin Exp Pathol 8(6):6716-23. eCollection 2015. 2015
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| 13 | CALM3, EGFR, SMARCD1
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| Comprehensive analysis of the association of EGFR, CALM3 and SMARCD1 gene polymorphisms with BMD in Caucasian women.
|
| Zhou QH, Zhao LJ, Wang P, Badr R, Xu XJ, Bu FX, Lappe J, Recker R, Zhou Y, Ye A, Zhou BT.
|
| PLoS One 9(11):e112358. doi: 10.1371/journal.pone.0112358. eCollection 2014.
2014
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| 14 | EGFR
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| Sustained activation of EGFR triggers renal fibrogenesis after acute kidney injury.
|
| Tang J, Liu N, Tolbert E, Ponnusamy M, Ma L, Gong R, Bayliss G, Yan H, Zhuang S.
|
| Am J Pathol 183(1):160-72. doi: 10.1016/j.ajpath.2013.04.005. Epub 2013 May 15.
2013
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| 15 | EGFR
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| A pathophysiologic role for epidermal growth factor receptor in pemphigus acantholysis.
|
| Bektas M, Jolly PS, Berkowitz P, Amagai M, Rubenstein DS.
|
| J Biol Chem 288(13):9447-56. doi: 10.1074/jbc.M112.438010. Epub 2013 Feb 12.
2013
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| 16 | AREG, EGFR
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| Amphiregulin enhances regulatory T cell-suppressive function via the epidermal growth factor receptor.
|
| Zaiss DM, van Loosdregt J, Gorlani A, Bekker CP, Gröne A, Sibilia M, van Bergen en Henegouwen PM, Roovers RC, Coffer PJ, Sijts AJ.
|
| Immunity 38(2):275-84. doi: 10.1016/j.immuni.2012.09.023. Epub 2013 Jan 17.
2013
|
| 17 | ADAM17, EGFR
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| ADAM17 transactivates EGFR signaling during embryonic eyelid closure.
|
| Hassemer EL, Endres B, Toonen JA, Ronchetti A, Dubielzig R, Sidjanin DJ.
|
| Invest Ophthalmol Vis Sci 54(1):132-40. doi: 10.1167/iovs.12-11130.
2013
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| 18 | EGFR, IL6, SOCS3, STAT3
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| STAT3 activation in response to IL-6 is prolonged by the binding of IL-6 receptor to EGF receptor.
|
| Wang Y, van Boxel-Dezaire AH, Cheon H, Yang J, Stark GR.
|
| Proc Natl Acad Sci U S A 110(42):16975-80. doi: 10.1073/pnas.1315862110. Epub 2013 Sep 30.
2013
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| 19 | EGFR, LIMA1
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| Epidermal growth factor promotes protein degradation of epithelial protein lost in neoplasm (EPLIN), a putative metastasis suppressor, during epithelial-mesenchymal transition.
|
| Zhang S, Wang X, Iqbal S, Wang Y, Osunkoya AO, Chen Z, Chen Z, Shin DM, Yuan H, Wang YA, Zhau HE, Chung LW, Ritenour C, Kucuk O, Wu D.
|
| J Biol Chem 288(3):1469-79. doi: 10.1074/jbc.M112.438341. Epub 2012 Nov 27.
2013
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| 20 | BECN1, EGFR
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| EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance.
|
| Wei Y, Zou Z, Becker N, Anderson M, Sumpter R, Xiao G, Kinch L, Koduru P, Christudass CS, Veltri RW, Grishin NV, Peyton M, Minna J, Bhagat G, Levine B.
|
| Cell 154(6):1269-84. doi: 10.1016/j.cell.2013.08.015.
2013
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| 21 | EGFR, PTPN2, STAT3
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| TCPTP regulates SFK and STAT3 signaling and is lost in triple-negative breast cancers.
|
| Shields BJ, Wiede F, Gurzov EN, Wee K, Hauser C, Zhu HJ, Molloy TJ, O'Toole SA, Daly RJ, Sutherland RL, Mitchell CA, McLean CA, Tiganis T.
|
| Mol Cell Biol 33(3):557-70. doi: 10.1128/MCB.01016-12. Epub 2012 Nov 19.
2013
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| 22 | EGFR, LYN, MCM7
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| Epidermal growth factor receptor potentiates MCM7-mediated DNA replication through tyrosine phosphorylation of Lyn kinase in human cancers.
|
| Huang TH, Huo L, Wang YN, Xia W, Wei Y, Chang SS, Chang WC, Fang YF, Chen CT, Lang JY, Tu C, Wang Y, Hsu MC, Kuo HP, Ko HW, Shen J, Lee HH, Lee PC, Wu Y, Chen CH, Hung MC.
|
| Cancer Cell 23(6):796-810. doi: 10.1016/j.ccr.2013.04.027.
2013
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| 23 | AP1B1, EGFR
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| Basolateral EGF receptor sorting regulated by functionally distinct mechanisms in renal epithelial cells.
|
| Cotton CU, Hobert ME, Ryan S, Carlin CR.
|
| Traffic 14(3):337-54. doi: 10.1111/tra.12032. Epub 2012 Dec 28.
2013
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| 24 | EGFR, LYN, YES1
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| Yes and Lyn play a role in nuclear translocation of the epidermal growth factor receptor.
|
| Iida M, Brand TM, Campbell DA, Li C, Wheeler DL.
|
| Oncogene 32(6):759-67. doi: 10.1038/onc.2012.90. Epub 2012 Mar 19. Erratum in: Oncogene. 2019 Mar;38(13):2435.
2013
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| 25 | EGF, EGFR, PTGES
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| EGFR signaling upregulates expression of microsomal prostaglandin E synthase-1 in cancer cells leading to enhanced tumorigenicity.
|
| Donnini S, Finetti F, Terzuoli E, Giachetti A, Ińiguez MA, Hanaka H, Fresno M, Rĺdmark O, Ziche M.
|
| Oncogene 31(29):3457-66. doi: 10.1038/onc.2011.503. Epub 2011 Nov 14.
2012
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| 26 | CHKA, EGFR
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| Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation.
|
| Miyake T, Parsons SJ.
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| Oncogene 31(11):1431-41. doi: 10.1038/onc.2011.332. Epub 2011 Aug 8.
2012
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| 27 | EGFR, GJA1, GJB1, GJB2
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| Epidermal growth factor regulates connexin 43 in the human epididymis: role of gap junctions in azoospermia.
|
| Dubé E, Dufresne J, Chan PT, Cyr DG.
|
| Hum Reprod 27(8):2285-96. doi: 10.1093/humrep/des164. Epub 2012 May 17. 2012
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| 28 | EGFR, HDAC6
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| HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.
|
| Liu W, Fan LX, Zhou X, Sweeney WE Jr, Avner ED, Li X.
|
| PLoS One 7(11):e49418. doi: 10.1371/journal.pone.0049418. Epub 2012 Nov 13.
2012
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| 29 | EGFR
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| EGF receptor is required for KRAS-induced pancreatic tumorigenesis.
|
| Ardito CM, Grüner BM, Takeuchi KK, Lubeseder-Martellato C, Teichmann N, Mazur PK, Delgiorno KE, Carpenter ES, Halbrook CJ, Hall JC, Pal D, Briel T, Herner A, Trajkovic-Arsic M, Sipos B, Liou GY, Storz P, Murray NR, Threadgill DW, Sibilia M, Washington MK, Wilson CL, Schmid RM, Raines EW, Crawford HC, Siveke JT.
|
| Cancer Cell 22(3):304-17. doi: 10.1016/j.ccr.2012.07.024.
2012
|
| 30 | EGFR, LGALS3
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| Galectin-3 regulates intracellular trafficking of EGFR through Alix and promotes keratinocyte migration.
|
| Liu W, Hsu DK, Chen HY, Yang RY, Carraway KL 3rd, Isseroff RR, Liu FT.
|
| J Invest Dermatol 132(12):2828-37. doi: 10.1038/jid.2012.211. Epub 2012 Jul 12.
2012
|
| 31 | ADAM17, EGFR
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| Epidermal ADAM17 maintains the skin barrier by regulating EGFR ligand-dependent terminal keratinocyte differentiation.
|
| Franzke CW, Cobzaru C, Triantafyllopoulou A, Löffek S, Horiuchi K, Threadgill DW, Kurz T, van Rooijen N, Bruckner-Tuderman L, Blobel CP.
|
| J Exp Med 209(6):1105-19. doi: 10.1084/jem.20112258. Epub 2012 May 7. Erratum in: J Exp Med. 2012 Dec 17;209(13):2517.
2012
|
| 32 | EGFR
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| Suppression of EGFR endocytosis by dynamin depletion reveals that EGFR signaling occurs primarily at the plasma membrane.
|
| Sousa LP, Lax I, Shen H, Ferguson SM, De Camilli P, Schlessinger J.
|
| Proc Natl Acad Sci U S A 109(12):4419-24. doi: 10.1073/pnas.1200164109. Epub 2012 Feb 27.
2012
|
| 33 | EGFR
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| EGFR signaling is required for regenerative proliferation in the cochlea: conservation in birds and mammals.
|
| White PM, Stone JS, Groves AK, Segil N.
|
| Dev Biol 363(1):191-200. doi: 10.1016/j.ydbio.2011.12.035. Epub 2012 Jan 2.
2012
|
| 34 | CDCP1, EGFR
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| The cell surface glycoprotein CUB domain-containing protein 1 (CDCP1) contributes to epidermal growth factor receptor-mediated cell migration.
|
| Dong Y, He Y, de Boer L, Stack MS, Lumley JW, Clements JA, Hooper JD.
|
| J Biol Chem 287(13):9792-803. doi: 10.1074/jbc.M111.335448. Epub 2012 Feb 7.
2012
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| 35 | EGFR
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| Endosomal accumulation of the activated epidermal growth factor receptor (EGFR) induces apoptosis.
|
| Rush JS, Quinalty LM, Engelman L, Sherry DM, Ceresa BP.
|
| J Biol Chem 287(1):712-22. doi: 10.1074/jbc.M111.294470. Epub 2011 Nov 18.
2012
|
| 36 | EGFR, GRB2, TNK2
|
| The activation mechanism of ACK1 (activated Cdc42-associated tyrosine kinase 1).
|
| Lin Q, Wang J, Childress C, Yang W.
|
| Biochem J 445(2):255-64. doi: 10.1042/BJ20111575.
2012
|
| 37 | EGFR, OPRM1
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| OPRM1 and EGFR contribute to skin pigmentation differences between Indigenous Americans and Europeans.
|
| Quillen EE, Bauchet M, Bigham AW, Delgado-Burbano ME, Faust FX, Klimentidis YC, Mao X, Stoneking M, Shriver MD.
|
| Hum Genet 131(7):1073-80. doi: 10.1007/s00439-011-1135-1. Epub 2011 Dec 24.
2012
|
| 38 | EGFR, STYK1
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| NOK/STYK1 has a strong tendency towards forming aggregates and colocalises with epidermal growth factor receptor in endosomes.
|
| Ding X, Jiang QB, Li R, Chen S, Zhang S.
|
| Biochem Biophys Res Commun 421(3):468-73. doi: 10.1016/j.bbrc.2012.04.016. Epub 2012 Apr 9.
2012
|
| 39 | EGFR, RAB21
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| Rab21 attenuates EGF-mediated MAPK signaling through enhancing EGFR internalization and degradation.
|
| Yang X, Zhang Y, Li S, Liu C, Jin Z, Wang Y, Ren F, Chang Z.
|
| Biochem Biophys Res Commun 421(4):651-7. doi: 10.1016/j.bbrc.2012.04.049. Epub 2012 Apr 14.
2012
|
| 40 | BIN1, EGFR, RIN1
|
| RIN1 orchestrates the activation of RAB5 GTPases and ABL tyrosine kinases to determine the fate of EGFR.
|
| Balaji K, Mooser C, Janson CM, Bliss JM, Hojjat H, Colicelli J.
|
| J Cell Sci 125(Pt 23):5887-96. doi: 10.1242/jcs.113688. Epub 2012 Sep 12.
2012
|
| 41 | EGFR, NFKB1
|
| FAS and NF-κB signalling modulate dependence of lung cancers on mutant EGFR.
|
| Bivona TG, Hieronymus H, Parker J, Chang K, Taron M, Rosell R, Moonsamy P, Dahlman K, Miller VA, Costa C, Hannon G, Sawyers CL.
|
| Nature 471(7339):523-6.
2011
|
| 42 | EGFR, IQGAP1
|
| MAPK scaffold IQGAP1 binds the EGF receptor and modulates its activation.
|
| McNulty DE, Li Z, White CD, Sacks DB, Annan RS.
|
| J Biol Chem 286(17):15010-21. Epub 2011 Feb 24.
2011
|
| 43 | EGFR
|
| Regulation of human EGF receptor by lipids.
|
| Coskun Ü, Grzybek M, Drechsel D, Simons K.
|
| Proc Natl Acad Sci U S A 108(22):9044-8. Epub 2011 May 13.
2011
|
| 44 | EGFR, MET
|
| Dual blockade of EGFR and c-Met abrogates redundant signaling and proliferation in head and neck carcinoma cells.
|
| Xu H, Stabile LP, Gubish CT, Gooding WE, Grandis JR, Siegfried JM.
|
| Clin Cancer Res 17(13):4425-38. Epub 2011 May 27.
2011
|
| 45 | EGFR, LGALS3, MUC1
|
| Galectin-3 regulates MUC1 and EGFR cellular distribution and EGFR downstream pathways in pancreatic cancer cells.
|
| Merlin J, Stechly L, de Beaucé S, Monté D, Leteurtre E, van Seuningen I, Huet G, Pigny P.
|
| Oncogene 30(22):2514-25. doi: 10.1038/onc.2010.631. Epub 2011 Jan 24.
2011
|
| 46 | EGFR
|
| Epidermal growth factor receptors destined for the nucleus are internalized via a clathrin-dependent pathway.
|
| De Angelis Campos AC, Rodrigues MA, de Andrade C, de Goes AM, Nathanson MH, Gomes DA.
|
| Biochem Biophys Res Commun 412(2):341-6. Epub 2011 Jul 29.
2011
|
| 47 | APPL1, EGFR
|
| Adaptor protein containing PH domain, PTB domain and leucine zipper (APPL1) regulates the protein level of EGFR by modulating its trafficking.
|
| Lee JR, Hahn HS, Kim YH, Nguyen HH, Yang JM, Kang JS, Hahn MJ.
|
| Biochem Biophys Res Commun 415(1):206-11. doi: 10.1016/j.bbrc.2011.10.064. Epub 2011 Oct 19. 2011
|
| 48 | EGFr, USP18
|
| Usp18 regulates epidermal growth factor (EGF) receptor expression and cancer cell survival via microRNA-7.
|
| Duex JE, Comeau L, Sorkin A, Purow B, Kefas B.
|
| J Biol Chem 286(28):25377-86. doi: 10.1074/jbc.M111.222760. Epub 2011 May 18.
2011
|
| 49 | EGFR, FKBP1A
|
| Suppression of EGFR autophosphorylation by FKBP12.
|
| Mathea S, Li S, Schierhorn A, Jahreis G, Schiene-Fischer C.
|
| Biochemistry 50(50):10844-50. doi: 10.1021/bi2013855. Epub 2011 Nov 28.
2011
|
| 50 | BCL2L11, EGFR, NOTCH3
|
| Notch3 cooperates with the EGFR pathway to modulate apoptosis through the induction of bim.
|
| Konishi J, Yi F, Chen X, Vo H, Carbone DP, Dang TP.
|
| Oncogene 29(4):589-96. Epub 2009 Nov 2.
2010
|
| 51 | EGFR, VAV2
|
| VAV2 regulates epidermal growth factor receptor endocytosis and degradation.
|
| Thalappilly S, Soubeyran P, Iovanna JL, Dusetti NJ.
|
| Oncogene 29(17):2528-39. Epub 2010 Feb 8.
2010
|
| 52 | EGFR, ERBB2, PTPN9
|
| Protein-tyrosine phosphatase PTPN9 negatively regulates ErbB2 and epidermal growth factor receptor signaling in breast cancer cells.
|
| Yuan T, Wang Y, Zhao ZJ, Gu H.
|
| J Biol Chem 285(20):14861-70. Epub 2010 Mar 24.PMID: 20335174 2010
|
| 53 | EGFR, ERRFI1, STX8
|
| Mig-6 controls EGFR trafficking and suppresses gliomagenesis.
|
| Ying H, Zheng H, Scott K, Wiedemeyer R, Yan H, Lim C, Huang J, Dhakal S, Ivanova E, Xiao Y, Zhang H, Hu J, Stommel JM, Lee MA, Chen AJ, Paik JH, Segatto O, Brennan C, Elferink LA, Wang YA, Chin L, DePinho RA.
|
| Proc Natl Acad Sci U S A. 107(15):6912-7. 2010
|
| 54 | EGFR, HDAC6
|
| The microtubule-associated histone deacetylase 6 (HDAC6) regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation.
|
| Gao YS, Hubbert CC, Yao TP.
|
| J Biol Chem 285(15):11219-26. Epub 2010 Feb 4.
2010
|
| 55 | CD44, EGFR, MMP9
|
| Role of matrix metalloproteinase-9 dimers in cell migration: design of inhibitory peptides.
|
| Dufour A, Zucker S, Sampson NS, Kuscu C, Cao J.
|
| J Biol Chem 285(46):35944-56. Epub 2010 Sep 13.
2010
|
| 56 | CPEB3, EGFR
|
| A novel role of CPEB3 in regulating EGFR gene transcription via association with Stat5b in neurons.
|
| Peng SC, Lai YT, Huang HY, Huang HD, Huang YS.
|
| Nucleic Acids Res 38(21):7446-57. Epub 2010 Jul 17.
2010
|
| 57 | EGFR, IQGAP1, KSR1, MAPK1, MAPK3, PLA2G4A
|
| Ras subcellular localization defines extracellular signal-regulated kinase 1 and 2 substrate specificity through distinct utilization of scaffold proteins.
|
| Casar B, Arozarena I, Sanz-Moreno V, Pinto A, Agudo-Ibáńez L, Marais R, Lewis RE, Berciano MT, Crespo P.
|
| Mol Cell Biol 29(5):1338-53. Epub 2008 Dec 29.
2009
|
| 58 | EGFR
|
| A comparison of EGFR and KRAS status in primary lung carcinoma and matched metastases.
|
| Monaco SE, Nikiforova MN, Cieply K, Teot LA, Khalbuss WE, Dacic S.
|
| Hum Pathol um Pathol. 2009 Sep 7. [Epub ahead of print]
2009
|
| 59 | EGFR
|
| Epidermal growth factor receptor mutations and the clinical outcome in male smokers with squamous cell carcinoma of lung.
|
| Park SH, Ha SY, Lee JI, Lee H, Sim H, Kim YS, Hong J, Park J, Cho EK, Shin DB, Lee JH.
|
| J Korean Med Sci 24(3):448-52. Epub 2009 Jun 12.
2009
|
| 60 | EGFR, ZGPAT
|
| ZIP: a novel transcription repressor, represses EGFR oncogene and suppresses breast carcinogenesis.
|
| Li R, Zhang H, Yu W, Chen Y, Gui B, Liang J, Wang Y, Sun L, Yang X, Zhang Y, Shi L, Li Y, Shang Y.
|
| EMBO J 28(18):2763-76. Epub 2009 Jul 30.
2009
|
| 61 | EGFR, TOM1L1
|
| Participation of Tom1L1 in EGF-stimulated endocytosis of EGF receptor.
|
| Liu NS, Loo LS, Loh E, Seet LF, Hong W.
|
| EMBO J 28(22):3485-99. Epub 2009 Oct 1.PMID: 19798056 2009
|
| 62 | EGFR, MT-CO2
|
| Epidermal growth factor receptor translocation to the mitochondria: regulation and effect.
|
| Demory ML, Boerner JL, Davidson R, Faust W, Miyake T, Lee I, Hüttemann M, Douglas R, Haddad G, Parsons SJ.
|
| J Biol Chem 284(52):36592-604. Epub 2009 Oct 19. 2009
|
| 63 | EGFR, USP18
|
| RNA interference screen identifies Usp18 as a regulator of epidermal growth factor receptor synthesis.
|
| Duex JE, Sorkin A.
|
| Mol Biol Cell 20(6):1833-44. doi: 10.1091/mbc.E08-08-0880. Epub 2009 Jan 21.
2009
|
| 64 | EGFR
|
| The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP.
|
| Yun CH, Mengwasser KE, Toms AV, Woo MS, Greulich H, Wong KK, Meyerson M, Eck MJ.
|
| Proc Natl Acad Sci U S A 105(6):2070-5. Epub 2008 Jan 28. 2008
|
| 65 | RIPK1, EGFR
|
| RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR.
|
| Ramnarain DB, Paulmurugan R, Park S, Mickey BE, Asaithamby A, Saha D, Kelliher MA, Mukhopadhyay P, Banani F, Madden CJ, Wright PS, Chakravarty S, Habib AA.
|
| Cell Death Differ 15(2):344-53. Epub 2007 Nov 16. 2008
|
| 66 | EGFR, NOTCH1
|
| EGFR signalling as a negative regulator of Notch1 gene transcription and function in proliferating keratinocytes and cancer.
|
| Kolev V, Mandinova A, Guinea-Viniegra J, Hu B, Lefort K, Lambertini C, Neel V, Dummer R, Wagner EF, Dotto GP.
|
| Nat Cell Biol 10(8):902-11. Epub 2008 Jul 6.
2008
|
| 67 | EGFR, SLC12A2
|
| Induction of Na+/K+/2Cl- cotransporter expression mediates chronic potentiation of intestinal epithelial Cl- secretion by EGF.
|
| O'Mahony F, Toumi F, Mroz MS, Ferguson G, Keely SJ.
|
| Am J Physiol Cell Physiol 294(6):C1362-70. Epub 2008 Apr 9.
2008
|
| 68 | EGFR, RIPK1
|
| RIP1 links inflammatory and growth factor signaling pathways by regulating expression of the EGFR.
|
| Ramnarain DB, Paulmurugan R, Park S, Mickey BE, Asaithamby A, Saha D, Kelliher MA, Mukhopadhyay P, Banani F, Madden CJ, Wright PS, Chakravarty S, Habib AA.
|
| Cell Death Differ 15(2):344-53. Epub 2007 Nov 16.PMID: 18007664 2008
|
| 69 | EGFR, ERBB2, ERBB3, ERBB4
|
| N-glycan of ErbB family plays a crucial role in dimer formation and tumor promotion.
|
| Takahashi M, Yokoe S, Asahi M, Lee SH, Li W, Osumi D, Miyoshi E, Taniguchi N.
|
| Biochim Biophys Acta 1780(3):520-4. Epub 2007 Nov 6.PMID: 18036567 2008
|
| 70 | EGFR, ERBB2, ERBB3, ERBB4
|
| Characterization of a novel tripartite nuclear localization sequence in the EGFR family.
|
| Hsu SC, Hung MC.
|
| J Biol Chem 282(14):10432-40. Epub 2007 Feb 5. 2007
|
| 71 | EGFR
|
| The EGF receptor is required for efficient liver regeneration.
|
| Natarajan A, Wagner B, Sibilia M.
|
| Proc Natl Acad Sci U S A 104(43):17081-6. Epub 2007 Oct 16. 2007
|
| 72 | EGFR, EPHA2
|
| Activation of the EGFR gene target EphA2 inhibits epidermal growth factor-induced cancer cell motility.
|
| Larsen AB, Pedersen MW, Stockhausen MT, Grandal MV, van Deurs B, Poulsen HS.
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