| 1 | EDEM1, EDEM2, TXNDC11
|
| Mannosidase activity of EDEM1 and EDEM2 depends on an unfolded state of their glycoprotein substrates.
|
| Shenkman M, Ron E, Yehuda R, Benyair R, Khalaila I, Lederkremer GZ.
|
| Commun Biol. Oct 18;1:172. doi: 10.1038/s42003-018-0174-8. 2018
|
| 2 | EDEM1, EDEM2
|
| The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol.
|
| Słomińska-Wojewódzka M, Pawlik A, Sokołowska I, Antoniewicz J, Węgrzyn G, Sandvig K.
|
| Biochem J 457(3):485-96. doi: 10.1042/BJ20130155.
2014
|
| 3 | EDEM1
|
| A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins.
|
| Shenkman M, Groisman B, Ron E, Avezov E, Hendershot LM, Lederkremer GZ.
|
| J Biol Chem 288(4):2167-78. doi: 10.1074/jbc.M112.438275. Epub 2012 Dec 11.
2013
|
| 4 | EDEM1
|
| Tyrosinase degradation is prevented when EDEM1 lacks the intrinsically disordered region.
|
| Marin MB, Ghenea S, Spiridon LN, Chiritoiu GN, Petrescu AJ, Petrescu SM.
|
| PLoS One 7(8):e42998. doi: 10.1371/journal.pone.0042998. Epub 2012 Aug 8.
2012
|
| 5 | EDEM1, ERLEC1
|
| Mannose trimming is required for delivery of a glycoprotein from EDEM1 to XTP3-B and to late endoplasmic reticulum-associated degradation steps.
|
| Groisman B, Shenkman M, Ron E, Lederkremer GZ.
|
| J Biol Chem 286(2):1292-300. Epub 2010 Nov 9.
2011
|
| 6 | EDEM1
|
| Characterization of early EDEM1 protein maturation events and their functional implications.
|
| Tamura T, Cormier JH, Hebert DN.
|
| J Biol Chem 286(28):24906-15. Epub 2011 Jun 1.
2011
|
| 7 | DNAJC10, EDEM1
|
| Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.
|
| Hagiwara M, Maegawa K, Suzuki M, Ushioda R, Araki K, Matsumoto Y, Hoseki J, Nagata K, Inaba K.
|
| Mol Cell 41(4):432-44. doi: 10.1016/j.molcel.2011.01.021.
2011
|
| 8 | EDEM1
|
| EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans.
|
| Hosokawa N, Tremblay LO, Sleno B, Kamiya Y, Wada I, Nagata K, Kato K, Herscovics A.
|
| Glycobiology 20(5):567-75. Epub 2010 Jan 11.
2010
|
| 9 | EDEM1
|
| A dual role for EDEM1 in the processing of rod opsin.
|
| Kosmaoglou M, Kanuga N, Aguilą M, Garriga P, Cheetham ME.
|
| J Cell Sci 122(Pt 24):4465-72. Epub 2009 Nov 24.
2009
|
| 10 | EDEM1
|
| EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex.
|
| Cormier JH, Tamura T, Sunryd JC, Hebert DN.
|
| Mol Cell 34(5):627-33.
2009
|
| 11 | DNAJC10, EDEM1, HSPA5
|
| ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.
|
| Ushioda R, Hoseki J, Araki K, Jansen G, Thomas DY, Nagata K.
|
| Science 321(5888):569-72.
2008
|
| 12 | EDEM1
|
| EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sites.
|
| Zuber C, Cormier JH, Guhl B, Santimaria R, Hebert DN, Roth J.
|
| Proc Natl Acad Sci U S A 104(11):4407-12. Epub 2007 Mar 6. 2007
|
| 13 | EDEM1, EDEM2, EDEM3
|
| Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins.
|
| Olivari S, Molinari M.
|
| FEBS Lett 581(19):3658-64. Epub 2007 May 4. Review. 2007
|
| 14 | EDEM1
|
| EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.
|
| Olivari S, Cali T, Salo KE, Paganetti P, Ruddock LW, Molinari M.
|
| Biochem Biophys Res Commun 349(4):1278-84. Epub 2006 Sep 12. 2006
|
| 15 | DERL2, DERL3, EDEM1
|
| Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.
|
| Oda Y, Okada T, Yoshida H, Kaufman RJ, Nagata K, Mori K.
|
| J Cell Biol 172(3):383-93.
2006
|
| 16 | EDEM2, EDEM1, EDEM3
|
| A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation.
|
| Olivari S, Galli C, Alanen H, Ruddock L, Molinari M.
|
| J Biol Chem 280(4):2424-8. Epub 2004 Dec 3. 2005
|
| 17 | EDEM1
|
| Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle.
|
| Molinari M, Calanca V, Galli C, Lucca P, Paganetti P.
|
| Science 299(5611):1397-400. 2003
|
| 18 | EDEM1
|
| A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation.
|
| Hosokawa N, Wada I, Hasegawa K, Yorihuzi T, Tremblay LO, Herscovics A, Nagata K.
|
| EMBO Rep 2(5):415-22. 2001
|
| 19 | ANKS1A, BCL2L2, DCUN1D4, DHX38, DHX38, DVL3, EDEM1, FAM38A, FIG4, GCN1L1, HSPH1, IHPK1, KIAA0232, KIAA0240, KIAA0247, LARP4B, LPGAT1, LRRC8B, MFN2, MRPS27, NCSTN, NUP205, PHF15, PHF16, PHYHIP, PIEZO1, PUM2, RAPGEF5, RGP1, RIMS3, RNF10, RTF1, RUBCN, SNX19, SPOCK2, STAB1, TATDN2, TBC1D5, TIAF1, TM9SF4, TOPBP1, WAPL, WASF1, ZNF516, ZNF516, ZNF592
|
| Prediction of the coding sequences of unidentified human genes. VI. the coding sequences of 80 new genes (KIAA0201-KIAA0280) deduced by analysis of cDNA clones from cell line KG-1 and brain.
|
| Nagase T, et al.
|
| DNA Res 3 : 321-329,341-54. 1996
|