Citations for
1E2F1, E2F2, E2F3, E2F5, E2F6
Roles of E2F family members in the diagnosis and prognosis of head and neck squamous cell carcinoma
Li Y, Huang Y, Li B, Yang K.
BMC Med Genomics. Feb 28;16(1):38. doi: 10.1186/s12920-023-01470-6 2023
2E2F6
E2F6 initiates stable epigenetic silencing of germline genes during embryonic development. 2021 PMID:
Dahlet T, Truss M, Frede U, Al Adhami H, Bardet AF, Dumas M, Vallet J, Chicher J, Hammann P, Kottnik S, Hansen P, Luz U, Alvarez G, Auclair G, Hecht J, Robinson PN, Hagemeier C, Weber M.
Nat Commun. Jun 11;12(1):3582. doi: 10.1038/s41467-021-23596-w. 2021
3DUSP1, E2F6, USP22
Deubiquitination of the repressor E2F6 by USP22 facilitates AKT activation and tumor growth in hepatocellular carcinoma
Jing T, Wang B, Yang Z, Liu Y, Xu G, Xu X, Jiao K, Chen Z, Xiang L, Zhang L, Liu Y.
Cancer Lett. Oct 10;518:266-277. doi: 10.1016/j.canlet.2021.07.044. Epub 2021 Jul 30. 2021
4E2F6
E2F-dependent transcription determines replication capacity and S phase length.
Pennycook BR, Vesela E, Peripolli S, Singh T, Barr AR, Bertoli C, de Bruin RAM.
Nat Commun. Jul 14;11(1):3503. doi: 10.1038/s41467-020-17146-z 2020
5E2F6, NR2E1
Nuclear receptor TLX regulates islet beta cell proliferation via E2F6.
Shi X, Ma D, Li M, Zeng L, Chen J, Yang Y.
Biochem Biophys Res Commun. Jun 4;513(3):560-566. doi: 10.1016/j.bbrc.2019.04.033. Epub 2019 Apr 10. 2019
6E2F6
E2F6 functions as a competing endogenous RNA, and transcriptional repressor, to promote ovarian cancer stemness.
Cheng FHC, Lin HY, Hwang TW, Chen YC, Huang RL, Chang CB, Yang W, Lin RI, Lin CW, Chen GCW, Mai SY, Lin JMJ, Chuang YM, Chou JL, Kuo LW, Li C, Cheng ASL, Lai HC, Wu SF, Tsai JC, Chan MWY.
Cancer Sci. Mar;110(3):1085-1095. doi: 10.1111/cas.13920. Epub 2019 Jan 25. 2019
7E2F6
E2F6 protein levels modulate drug induced apoptosis in cardiomyocytes.
Major JL, Salih M, Tuana BS.
Cell Signal. Dec;40:230-238. doi: 10.1016/j.cellsig.2017.09.022. Epub 2017 Sep 28. 2017
8CHEK1, E2F6
Chk1 inhibits E2F6 repressor function in response to replication stress to maintain cell-cycle transcription
Bertoli C, Klier S, McGowan C, Wittenberg C, de Bruin RA.
Curr Biol. Sep 9;23(17):1629-37. doi: 10.1016/j.cub.2013.06.063. Epub 2013 Aug 15. 2013
9E2F6, SMARCA4
E2F6 associates with BRG1 in transcriptional regulation
Leung JY, Nevins JR.
PLoS One. 7(10):e47967. doi: 10.1371/journal.pone.0047967. Epub 2012 Oct 17 2012
10E2F6
The E2F6 repressor activates gene expression in myocardium resulting in dilated cardiomyopathy
Westendorp B, Major JL, Nader M, Salih M, Leenen FH, Tuana BS.
FASEB J. Jun;26(6):2569-79. doi: 10.1096/fj.11-203174. Epub 2012 Mar 7. 2012
11E2F1, E2F6
E2F6 inhibits cobalt chloride-mimetic hypoxia-induced apoptosis through E2F1.
Yang WW, Shu B, Zhu Y, Yang HT.
Mol Biol Cell 19(9):3691-700. Epub 2008 Jun 18.PMID: 18562691 2008
12E2F1, E2F2, E2F3, E2F4, E2F5, E2F6
Comparative analysis of E2F family member oncogenic activity.
Chen C, Wells AD.
PLoS ONE 2(9):e912. 2007
13E2F1, E2F2, E2F4, E2F6
E2F-6 suppresses growth-associated apoptosis of human hematopoietic progenitor cells by counteracting proapoptotic activity of E2F-1.
Kikuchi J, Shimizu R, Wada T, Ando H, Nakamura M, Ozawa K, Furukawa Y.
Stem Cells 25(10):2439-47. Epub 2007 Jun 28.PMID: 17600109 2007
14E2F6
A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner.
Attwooll C, Oddi S, Cartwright P, Prosperini E, Agger K, Steensgaard P, Wagener C, Sardet C, Moroni MC, Helin K.
J Biol Chem 280(2):1199-208. Epub 2004 Nov 8. 2005
15E2F6, EPC1, EZH2
A novel repressive E2F6 complex containing the polycomb group protein, EPC1, that interacts with EZH2 in a proliferation-specific manner.
Attwooll C, Oddi S, Cartwright P, Prosperini E, Agger K, Steensgaard P, Wagener C, Sardet C, Moroni MC, Helin K.
J Biol Chem 280(2):1199-208. Epub 2004 Nov 8.PMID: 15536069 2005
16E2F6, E2F6P
Human E2F6 is alternatively spliced to generate multiple protein isoforms.
Kherrouche Z, De Launoit Y, Monte D.
Biochem Biophys Res Commun 317(3):749-60. 2004
17E2F6
E2F-6: a novel member of the E2F family is an inhibitor of E2F-dependent transcription.
Cartwright P, Muller H, Wagener C, Holm K, Helin K.
Oncogene 17(5):611-23. 1998
18E2F6
Unusual proliferation arrest and transcriptional control properties of a newly discovered E2F family member, E2F-6.
Gaubatz S, Wood JG, Livingston DM.
Proc Natl Acad Sci U S A 95(16):9190-5. 1998
19E2F6
E2F-6, a member of the E2F family that can behave as a transcriptional repressor.
Trimarchi JM, Fairchild B, Verona R, Moberg K, Andon N, Lees JA.
Proc Natl Acad Sci U S A 95(6):2850-5. 1998