Citations for
1DYRK2
Engagement of DYRK2 in proper control for cell division.
Nihira NT, Yoshida K.
Cell Cycle ell Cycle. 2015 Jan 20:0. [Epub ahead of print] 2015
2DYRK2, NR1I2, UBR5
Stability of the human pregnane X receptor is regulated by E3 ligase UBR5 and serine/threonine kinase DYRK2.
Ong SS, Goktug AN, Elias A, Wu J, Saunders D, Chen T.
Biochem J 459(1):193-203. doi: 10.1042/BJ20130558. 2014
3DYRK2
Downregulation of DYRK2 can be a predictor of recurrence in early stage breast cancer.
Enomoto Y, Yamashita S, Yoshinaga Y, Fukami Y, Miyahara S, Nabeshima K, Iwasaki A.
Tumour Biol 35(11):11021-5. doi: 10.1007/s13277-014-2413-z. Epub 2014 Aug 6. 2014
4DDB1, DYRK2, TERT, UBR5, VPRBP
Dyrk2-associated EDD-DDB1-VprBP E3 ligase inhibits telomerase by TERT degradation.
Jung HY, Wang X, Jun S, Park JI.
J Biol Chem 288(10):7252-62. doi: 10.1074/jbc.M112.416792. Epub 2013 Jan 28. 2013
5DYRK2
Drosophila Dyrk2 plays a role in the development of the visual system.
Luebbering N, Charlton-Perkins M, Kumar JP, Lochead PA, Rollmann SM, Cook T, Cleghon V.
PLoS One 8(10):e76775. doi: 10.1371/journal.pone.0076775. eCollection 2013. Erratum in: PLoS One. 2014;9(3):e92344. Lochead, Pamela A [ad 2013
6DYRK2, SNAI1
DYRK2 controls the epithelial-mesenchymal transition in breast cancer by degrading Snail.
Mimoto R, Taira N, Takahashi H, Yamaguchi T, Okabe M, Uchida K, Miki Y, Yoshida K.
Cancer Lett 339(2):214-25. doi: 10.1016/j.canlet.2013.06.005. Epub 2013 Jun 18. 2013
7DYRK2, SIAH2
Mutual regulation between SIAH2 and DYRK2 controls hypoxic and genotoxic signaling pathways.
Pérez M, García-Limones C, Zapico I, Marina A, Schmitz ML, Muñoz E, Calzado MA.
J Mol Cell Biol 4(5):316-30. doi: 10.1093/jmcb/mjs047. Epub 2012 Aug 9. 2012
8DYRK2, JUN, MYC
DYRK2 priming phosphorylation of c-Jun and c-Myc modulates cell cycle progression in human cancer cells.
Taira N, Mimoto R, Kurata M, Yamaguchi T, Kitagawa M, Miki Y, Yoshida K.
J Clin Invest 122(3):859-72. doi: 10.1172/JCI60818. Epub 2012 Feb 6. 2012
9DYRK1A, DYRK2, DYRK3, DYRK4
Splice variants of the dual specificity tyrosine phosphorylation-regulated kinase 4 (DYRK4) differ in their subcellular localization and catalytic activity.
Papadopoulos C, Arato K, Lilienthal E, Zerweck J, Schutkowski M, Chatain N, Müller-Newen G, Becker W, de la Luna S.
J Biol Chem 286(7):5494-505. Epub 2010 Dec 2. 2011
10ATM, DYRK2, MDM2
ATM augments nuclear stabilization of DYRK2 by inhibiting MDM2 in the apoptotic response to DNA damage.
Taira N, Yamamoto H, Yamaguchi T, Miki Y, Yoshida K.
J Biol Chem 285(7):4909-19. Epub 2009 Dec 4. 2010
11DYRK2
Protein kinase DYRK2 is a scaffold that facilitates assembly of an E3 ligase.
Maddika S, Chen J.
Nat Cell Biol 11(4):409-19. Epub 2009 Mar 15. 2009
12DYRK2
DYRK2 expression may be a predictive marker for chemotherapy in non-small cell lung cancer.
Yamashita S, Chujo M, Moroga T, Anami K, Tokuishi K, Miyawaki M, Kawano Y, Takeno S, Yamamoto S, Kawahara K.
Anticancer Res 29(7):2753-7.PMID: 19596956 2009
13DYRK2, ABL1, PRKCD, PRKDC
Nuclear trafficking of pro-apoptotic kinases in response to DNA damage.
Yoshida K.
Trends Mol Med 14(7):305-13. Epub 2008 Jun 6. 2008
14DYRK2
Role for DYRK family kinases on regulation of apoptosis.
Yoshida K.
Biochem Pharmacol 76(11):1389-94. Epub 2008 Jul 2.PMID: 18599021 2008
15DYRK2
DYRK2 is targeted to the nucleus and controls p53 via Ser46 phosphorylation in the apoptotic response to DNA damage.
Taira N, Nihira K, Yamaguchi T, Miki Y, Yoshida K.
Mol Cell 25(5):725-38. 2007
16DYRK2, GRB7, SVIL, CCNC
Identification of genes with correlated patterns of variations in DNA copy number and gene expression level in gastric cancer.
Yang S, Jeung HC, Jeong HJ, Choi YH, Kim JE, Jung JJ, Rha SY, Yang WI, Chung HC.
Genomics 89(4):451-9. Epub 2007 Jan 16. 2007
17DYRK1A, DYRK1B, DYRK2, DYRK3, DYRK4
DYRK gene structure and erythroid-restricted features of DYRK3 gene expression.
Zhang D, Li K, Erickson-Miller CL, Weiss M, Wojchowski DM.
Genomics 85(1):117-30. 2005
18DYRK1A, DYRK2, DYRK3, DYRK4
Sequence characteristics, subcellular localization, and substrate specificity of DYRK-related kinases, a novel family of dual specificity protein kinases.
Becker W, et al.
J Biol Chem 273 : 25893-25902. 1998